Click here to switch to the map view.

The map label for this gene is ribBA [H]

Identifier: 209694493

GI number: 209694493

Start: 1022450

End: 1023559

Strand: Direct

Name: ribBA [H]

Synonym: VSAL_I0924

Alternate gene names: 209694493

Gene position: 1022450-1023559 (Clockwise)

Preceding gene: 209694492

Following gene: 209694494

Centisome position: 30.75

GC content: 41.8

Gene sequence:

>1110_bases
ATGGCAATTAGCTCAGCAAAAGACATTATTGAAGATATTCGCTTAGGTAAGATGGTTATTCTGATGGATGATGAAGATCG
TGAAAATGAAGGCGATTTAATCATTGCAGCAGAAAAAATTACACCAGAAGCAATCAATTTCATGGCAACACATGGCCGTG
GTTTAATTTGTTTAACAATGACAAAAGATCGCTGTGAAAAGTTAGGTCTGCCACCAATGGTGCAAGACAATAACGCACAA
TTTACAACTAACTTTACGGTTTCTATTGAAGCCGCTGAAGGGGTGACTACGGGTATTTCAGCAGCAGACCGTTCTCGTAC
TGTTGAAGCTGCAGTTGCTAAAAATGCCGTTGCTGCTGATCTTGTTCAGCCAGGCCACATTTTCCCTCTTGCTGCACAAG
AAGGCGGTGTGTTAACTCGTGCTGGACACACTGAAGCGGGTTGTGATTTAGCTCGTTTAGCCGGTTTTGAACCTGCAGGT
GTTATCGTTGAAATCCTAAATGATGATGGCTCTATGGCTCGTCGTCCTGACTTGGAAATTTTTGCTGAAAAACACGATGT
TAAATTGGGTACGATTGCTGACTTAATTGAATACCGTAATAATAACGAAACAACGATTGAACGTGTTGCTGAGTGTAAAT
TACCAACAGAGTTTGGTGATTTTGATCTAGTGACGTACCGTGACACGATTGATAATCAGCTTCATTATGCAATGAAAAAA
GAAAATACATCAGGCATTGCGCCATTAGTACGAGTTCACCTTCAAGACACCTTCACTGATATTCTTTATTCAGATCGTTG
TGCAGAACGTAGCTGGACATTACCAATGGCAATGCAACGTATAGCGGCCGAAGGTGGTGTACTTATTATTCTTGGTAATG
AAGAATCAACGGACAGCATTGTTCATAAAATCAAAGCATTAGAGCGTCAGGATAATGGTGAGTCGCCTACAATGGCGAAG
AAGCAAGGTACGTCGCGTCGCGTTGGTGTAGGCTCACAAATCTTAGCGGATATGGGTATCTCAGACATGCGTCTGCTGTC
ATCTTCTTCAAAGCGCTATCATTCATTGTCAGGCTTTGGTCTGAATGTAGTAGAATACGTCTCAAAATAA

Upstream 100 bases:

>100_bases
AGAAGAGCAACCTCAGTCTTCTGTTACGATGGATCTTTTGGCAAAATCAGGTTTTTTAAATTAACCATTTAACCTAACTA
ATATATTAAAGGTATTTCAC

Downstream 100 bases:

>100_bases
GTGTATTGATGGGCTCTATTGTGTAAATAGAGCCCAAATAATTAGATATTTGTCACAAAGCTGTGATAGAATTCGCCGAT
TCTCACTATGATATGTAGTT

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MAISSAKDIIEDIRLGKMVILMDDEDRENEGDLIIAAEKITPEAINFMATHGRGLICLTMTKDRCEKLGLPPMVQDNNAQ
FTTNFTVSIEAAEGVTTGISAADRSRTVEAAVAKNAVAADLVQPGHIFPLAAQEGGVLTRAGHTEAGCDLARLAGFEPAG
VIVEILNDDGSMARRPDLEIFAEKHDVKLGTIADLIEYRNNNETTIERVAECKLPTEFGDFDLVTYRDTIDNQLHYAMKK
ENTSGIAPLVRVHLQDTFTDILYSDRCAERSWTLPMAMQRIAAEGGVLIILGNEESTDSIVHKIKALERQDNGESPTMAK
KQGTSRRVGVGSQILADMGISDMRLLSSSSKRYHSLSGFGLNVVEYVSK

Sequences:

>Translated_369_residues
MAISSAKDIIEDIRLGKMVILMDDEDRENEGDLIIAAEKITPEAINFMATHGRGLICLTMTKDRCEKLGLPPMVQDNNAQ
FTTNFTVSIEAAEGVTTGISAADRSRTVEAAVAKNAVAADLVQPGHIFPLAAQEGGVLTRAGHTEAGCDLARLAGFEPAG
VIVEILNDDGSMARRPDLEIFAEKHDVKLGTIADLIEYRNNNETTIERVAECKLPTEFGDFDLVTYRDTIDNQLHYAMKK
ENTSGIAPLVRVHLQDTFTDILYSDRCAERSWTLPMAMQRIAAEGGVLIILGNEESTDSIVHKIKALERQDNGESPTMAK
KQGTSRRVGVGSQILADMGISDMRLLSSSSKRYHSLSGFGLNVVEYVSK
>Mature_368_residues
AISSAKDIIEDIRLGKMVILMDDEDRENEGDLIIAAEKITPEAINFMATHGRGLICLTMTKDRCEKLGLPPMVQDNNAQF
TTNFTVSIEAAEGVTTGISAADRSRTVEAAVAKNAVAADLVQPGHIFPLAAQEGGVLTRAGHTEAGCDLARLAGFEPAGV
IVEILNDDGSMARRPDLEIFAEKHDVKLGTIADLIEYRNNNETTIERVAECKLPTEFGDFDLVTYRDTIDNQLHYAMKKE
NTSGIAPLVRVHLQDTFTDILYSDRCAERSWTLPMAMQRIAAEGGVLIILGNEESTDSIVHKIKALERQDNGESPTMAKK
QGTSRRVGVGSQILADMGISDMRLLSSSSKRYHSLSGFGLNVVEYVSK

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=191, Percent_Identity=57.0680628272251, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1787533, Length=168, Percent_Identity=32.7380952380952, Blast_Score=80, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320695, Length=197, Percent_Identity=43.1472081218274, Blast_Score=164, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 40242; Mature: 40111

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAISSAKDIIEDIRLGKMVILMDDEDRENEGDLIIAAEKITPEAINFMATHGRGLICLTM
CCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHEECCCCEEEEEE
TKDRCEKLGLPPMVQDNNAQFTTNFTVSIEAAEGVTTGISAADRSRTVEAAVAKNAVAAD
CHHHHHHCCCCCEEECCCCEEEEEEEEEEECCCCCCCCCCHHCCCHHHHHHHHHHHHHHH
LVQPGHIFPLAAQEGGVLTRAGHTEAGCDLARLAGFEPAGVIVEILNDDGSMARRPDLEI
HCCCCCEEEEECCCCCEEEECCCCCCCCCHHHHCCCCCCCEEEEEECCCCCCCCCCCCEE
FAEKHDVKLGTIADLIEYRNNNETTIERVAECKLPTEFGDFDLVTYRDTIDNQLHYAMKK
EECCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEEEECCHHCCHHHHHHHC
ENTSGIAPLVRVHLQDTFTDILYSDRCAERSWTLPMAMQRIAAEGGVLIILGNEESTDSI
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCHHHH
VHKIKALERQDNGESPTMAKKQGTSRRVGVGSQILADMGISDMRLLSSSSKRYHSLSGFG
HHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCHHHHHHCCCHHHHHHHCCCHHHCCCCCCC
LNVVEYVSK
CHHHHHHCC
>Mature Secondary Structure 
AISSAKDIIEDIRLGKMVILMDDEDRENEGDLIIAAEKITPEAINFMATHGRGLICLTM
CCCHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHEECCCCEEEEEE
TKDRCEKLGLPPMVQDNNAQFTTNFTVSIEAAEGVTTGISAADRSRTVEAAVAKNAVAAD
CHHHHHHCCCCCEEECCCCEEEEEEEEEEECCCCCCCCCCHHCCCHHHHHHHHHHHHHHH
LVQPGHIFPLAAQEGGVLTRAGHTEAGCDLARLAGFEPAGVIVEILNDDGSMARRPDLEI
HCCCCCEEEEECCCCCEEEECCCCCCCCCHHHHCCCCCCCEEEEEECCCCCCCCCCCCEE
FAEKHDVKLGTIADLIEYRNNNETTIERVAECKLPTEFGDFDLVTYRDTIDNQLHYAMKK
EECCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEEEECCHHCCHHHHHHHC
ENTSGIAPLVRVHLQDTFTDILYSDRCAERSWTLPMAMQRIAAEGGVLIILGNEESTDSI
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCHHHH
VHKIKALERQDNGESPTMAKKQGTSRRVGVGSQILADMGISDMRLLSSSSKRYHSLSGFG
HHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCHHHHHHCCCHHHHHHHCCCHHHCCCCCCC
LNVVEYVSK
CHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339274 [H]