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The map label for this gene is nrdR

Identifier: 209694490

GI number: 209694490

Start: 1020181

End: 1020630

Strand: Direct

Name: nrdR

Synonym: VSAL_I0921

Alternate gene names: 209694490

Gene position: 1020181-1020630 (Clockwise)

Preceding gene: 209694486

Following gene: 209694491

Centisome position: 30.68

GC content: 39.11

Gene sequence:

>450_bases
ATGCATTGTCCATTTTGTAGTGCTACAGACACAAAAGTTATCGATTCTCGATTGGTTTCTGATGGTCATCAAGTTCGTCG
TCGTCGCCAATGTTTGGCGTGCAGTGAACGATTTACTACGTTTGAATCCGCTGAACTTGTTATGCCTAAAGTGATTAAGT
CTAATGGCAATCGTGAACCGTTTGATGAAGATAAATTATCGGGTGGTTTGTATCGTTCATTAGAAAAACGTCCCGTAAGT
GCTGATTTAGTTGAGCTTGCTTTGAATACAATTAAATCAAAGCTAAGAGCTACTGGTGAACGTGAAGTACCTTCGGAGAT
GATCGGCAATTTCGTTATGGATCAACTAAAGGAACTCGATAAAGTGGCGTATATTCGATTTGCATCCGTATATCGTAGCT
TTGAAGACATTAAAGAGTTCGGCGAAGAAATTGCAAAACTAGAGAAATAA

Upstream 100 bases:

>100_bases
AATAAGTAAAAACTTTGTATTAGTTACGTCTTCTTAGTCTCGGTGATAGGCACCGATCCGCTTTTCTTGTACACTAAACA
AAAAATAATAGGAGGCAAGA

Downstream 100 bases:

>100_bases
AATGAAATTTACTCCTCAAGATCACTTGATGATGCAGCGCGCTATTCAATTAGCTAAACGTGGTATTTATACGACGGCAC
CGAATCCAAATGTGGGCTGC

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MHCPFCSATDTKVIDSRLVSDGHQVRRRRQCLACSERFTTFESAELVMPKVIKSNGNREPFDEDKLSGGLYRSLEKRPVS
ADLVELALNTIKSKLRATGEREVPSEMIGNFVMDQLKELDKVAYIRFASVYRSFEDIKEFGEEIAKLEK

Sequences:

>Translated_149_residues
MHCPFCSATDTKVIDSRLVSDGHQVRRRRQCLACSERFTTFESAELVMPKVIKSNGNREPFDEDKLSGGLYRSLEKRPVS
ADLVELALNTIKSKLRATGEREVPSEMIGNFVMDQLKELDKVAYIRFASVYRSFEDIKEFGEEIAKLEK
>Mature_149_residues
MHCPFCSATDTKVIDSRLVSDGHQVRRRRQCLACSERFTTFESAELVMPKVIKSNGNREPFDEDKLSGGLYRSLEKRPVS
ADLVELALNTIKSKLRATGEREVPSEMIGNFVMDQLKELDKVAYIRFASVYRSFEDIKEFGEEIAKLEK

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=148, Percent_Identity=79.0540540540541, Blast_Score=246, Evalue=6e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_ALISL (B6EI95)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002262418.1
- GeneID:   6986734
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I0921
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- ProtClustDB:   PRK00464
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17025; Mature: 17025

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHCPFCSATDTKVIDSRLVSDGHQVRRRRQCLACSERFTTFESAELVMPKVIKSNGNREP
CCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
FDEDKLSGGLYRSLEKRPVSADLVELALNTIKSKLRATGEREVPSEMIGNFVMDQLKELD
CCHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
KVAYIRFASVYRSFEDIKEFGEEIAKLEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHCPFCSATDTKVIDSRLVSDGHQVRRRRQCLACSERFTTFESAELVMPKVIKSNGNREP
CCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
FDEDKLSGGLYRSLEKRPVSADLVELALNTIKSKLRATGEREVPSEMIGNFVMDQLKELD
CCHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
KVAYIRFASVYRSFEDIKEFGEEIAKLEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA