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The map label for this gene is ppiD [H]

Identifier: 209694402

GI number: 209694402

Start: 915001

End: 916857

Strand: Direct

Name: ppiD [H]

Synonym: VSAL_I0823

Alternate gene names: 209694402

Gene position: 915001-916857 (Clockwise)

Preceding gene: 209694401

Following gene: 209694403

Centisome position: 27.52

GC content: 38.45

Gene sequence:

>1857_bases
ATGATGGATCGAATTCGCGAAGGTTCAACTGGCCTCGTTGTTAAGATCATTCTCGGTCTAATTATTTTCTCATTTGTGTT
TGCAGGTGTAGGTAGTTATTTAGTCGGTGGTAGTCAACCTCTAGCGGCTAAAGTCGGTGAGCGTGAAATAACACGAAATG
ATTTTGAACAAGTTTATCAAAATGAACGCAACCGTATGCAATCTCAACTGGGCGAATATTTTTCGACTCTACTTGGTGAC
CCTGCGTATGTAGAGCAATTCCGAAAGTCAGTTTTAGATCGTATGGTCAATGATGCTTTACTCGATAACCAAGCTCAAGA
ACTTGGTTTACGTGTAAGTGATGAACAAATACGCCAAGCAATTTTATCTATGCCTCAGTTCCAAAAAGATGGAAAGTTTG
ACGAAGAAATCTTTAATGTCTCATTACGCCGCGCTGGTTTCACTTCAGACAGCTTCGCTGAGTATTTACGTGGTGATCTT
GTTCGTAATCAATTAGTGTCAGCGTTAGAATCAACGGAATTTACGCTAAGTAATGAAGTTAAAGCGCAAGGTGAACTTGA
AGGTCAGCAACGTGAAATTCGTACCATTACTTTAGATACAGCAACATTTGCTAAAAATGCAAAAGTGACTGAAGAAGAAG
TAAAAGAATACTATGATGCGAATAAACAACAATTTGTTCGTCCAGAACAAGTTAAAGTTTCTTATATTGAATTATCTGGT
GAATCATTGAAGGCACAAGCGCCAATTACTGATGAAGAAATTCAAACGTATTACAATGAGAATCAAGATAAGTACTCAAC
GCAAGAAAAACGTGAAGTAAGCCATATTCTTATCAAAGGTGACGAAGCTGACGCTCAAGCGGTTCTTGCTCGTTTAGATG
CAGGTGAAGATTTCGCTACTGTAGCGAAAGAAGACTCGCAAGATATTCCAACAGCAAAAGAAGGTGGTTCTTTAGGTTGG
ATTGAACGCGGTGTGATTGATCCTGAATTTGAAGATGCCGCTTTCCAACTTGTTAATGTAGGCGATCATTCAGGCTTAGT
TAAATCTGCATTTGGTTATCATATTATTCAATTAGATGCGATTGAAGCACCAAAAACTAAGCCTTTGGCTAAAGTAAGTG
CGGACATTAAAGCGTTTTTAGTTGATGAGCACGCTGCAGATGCTTTTTATAGCATGCAGACAGAATTAGCAGAAAAAGCA
TTTGAATCTCCTGATTCACTAGATGATGCTGCTGAAGCCGTAAATGCAAAAGTAATTACTTCTGATTTCTTCTCTCAAGC
GGATGCACCAGCATTGCTAGCAAATAGTGATGTGCTTCAAGCTATTTATAGCGCAGAAGTAAAAGAAGATGGCTTAAATT
CTGATGTTATTGAGATTGCTCCTGAACACGTAGTTGTTGTTCGTGTTGAAGAGTCTCGTGATGAAATGGTATTACCGTTA
GAAGAGGTTAAAGCGTCTGTTATTACTCGCTTATCTCAAGCTAAAGGTGAGCAAAAAGCATTAGAGTTAGCGAAGAATAT
AATTACGGCGTTAAATAAAGACGATGATGCATATTTATCAGAGCAAGGCTTAGTATTTACAGAAGCACGAATGATTACTC
GTGCAGATGAACTTGCTAACGATGTTTACCGTTTACAAAAACCGACTGCTGATAAGCCTACATACGCTCAAGTAATGGAT
CGACAAGGTAATAATGTCATTGTTGCTTTGGATGACGTACTAGAACTTGATAATAGCGCAATGGCTGAACAAGTAAGTAC
TCGTCTGCTTAGAACTCAGACACAACAAGATTTAACGGCGACACTTGATACGCTTAAATCTAATACTGAAATTAGTTATC
CATTATTAGAGCAATAA

Upstream 100 bases:

>100_bases
TTTCTTTTGTTGAACTATTTTTAATTTTCACTATCAATAGAAATTAACGTTTTCTTAGGGATTATCATCCCAATTCAGTG
ATTAGGAGCTAAAACATATT

Downstream 100 bases:

>100_bases
TTTAGTTCAATGTAATTGATAAGTAAATCAGACGGGCTCCTTATTGGAGCCCGTCGTGTTTTTAAAGAAGGCAAAGTTTT
CTTCATTGGGCTAATTCATC

Product: peptidyl-prolyl cis-trans isomerase D

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 618; Mature: 618

Protein sequence:

>618_residues
MMDRIREGSTGLVVKIILGLIIFSFVFAGVGSYLVGGSQPLAAKVGEREITRNDFEQVYQNERNRMQSQLGEYFSTLLGD
PAYVEQFRKSVLDRMVNDALLDNQAQELGLRVSDEQIRQAILSMPQFQKDGKFDEEIFNVSLRRAGFTSDSFAEYLRGDL
VRNQLVSALESTEFTLSNEVKAQGELEGQQREIRTITLDTATFAKNAKVTEEEVKEYYDANKQQFVRPEQVKVSYIELSG
ESLKAQAPITDEEIQTYYNENQDKYSTQEKREVSHILIKGDEADAQAVLARLDAGEDFATVAKEDSQDIPTAKEGGSLGW
IERGVIDPEFEDAAFQLVNVGDHSGLVKSAFGYHIIQLDAIEAPKTKPLAKVSADIKAFLVDEHAADAFYSMQTELAEKA
FESPDSLDDAAEAVNAKVITSDFFSQADAPALLANSDVLQAIYSAEVKEDGLNSDVIEIAPEHVVVVRVEESRDEMVLPL
EEVKASVITRLSQAKGEQKALELAKNIITALNKDDDAYLSEQGLVFTEARMITRADELANDVYRLQKPTADKPTYAQVMD
RQGNNVIVALDDVLELDNSAMAEQVSTRLLRTQTQQDLTATLDTLKSNTEISYPLLEQ

Sequences:

>Translated_618_residues
MMDRIREGSTGLVVKIILGLIIFSFVFAGVGSYLVGGSQPLAAKVGEREITRNDFEQVYQNERNRMQSQLGEYFSTLLGD
PAYVEQFRKSVLDRMVNDALLDNQAQELGLRVSDEQIRQAILSMPQFQKDGKFDEEIFNVSLRRAGFTSDSFAEYLRGDL
VRNQLVSALESTEFTLSNEVKAQGELEGQQREIRTITLDTATFAKNAKVTEEEVKEYYDANKQQFVRPEQVKVSYIELSG
ESLKAQAPITDEEIQTYYNENQDKYSTQEKREVSHILIKGDEADAQAVLARLDAGEDFATVAKEDSQDIPTAKEGGSLGW
IERGVIDPEFEDAAFQLVNVGDHSGLVKSAFGYHIIQLDAIEAPKTKPLAKVSADIKAFLVDEHAADAFYSMQTELAEKA
FESPDSLDDAAEAVNAKVITSDFFSQADAPALLANSDVLQAIYSAEVKEDGLNSDVIEIAPEHVVVVRVEESRDEMVLPL
EEVKASVITRLSQAKGEQKALELAKNIITALNKDDDAYLSEQGLVFTEARMITRADELANDVYRLQKPTADKPTYAQVMD
RQGNNVIVALDDVLELDNSAMAEQVSTRLLRTQTQQDLTATLDTLKSNTEISYPLLEQ
>Mature_618_residues
MMDRIREGSTGLVVKIILGLIIFSFVFAGVGSYLVGGSQPLAAKVGEREITRNDFEQVYQNERNRMQSQLGEYFSTLLGD
PAYVEQFRKSVLDRMVNDALLDNQAQELGLRVSDEQIRQAILSMPQFQKDGKFDEEIFNVSLRRAGFTSDSFAEYLRGDL
VRNQLVSALESTEFTLSNEVKAQGELEGQQREIRTITLDTATFAKNAKVTEEEVKEYYDANKQQFVRPEQVKVSYIELSG
ESLKAQAPITDEEIQTYYNENQDKYSTQEKREVSHILIKGDEADAQAVLARLDAGEDFATVAKEDSQDIPTAKEGGSLGW
IERGVIDPEFEDAAFQLVNVGDHSGLVKSAFGYHIIQLDAIEAPKTKPLAKVSADIKAFLVDEHAADAFYSMQTELAEKA
FESPDSLDDAAEAVNAKVITSDFFSQADAPALLANSDVLQAIYSAEVKEDGLNSDVIEIAPEHVVVVRVEESRDEMVLPL
EEVKASVITRLSQAKGEQKALELAKNIITALNKDDDAYLSEQGLVFTEARMITRADELANDVYRLQKPTADKPTYAQVMD
RQGNNVIVALDDVLELDNSAMAEQVSTRLLRTQTQQDLTATLDTLKSNTEISYPLLEQ

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=615, Percent_Identity=37.8861788617886, Blast_Score=410, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 68712; Mature: 68712

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDRIREGSTGLVVKIILGLIIFSFVFAGVGSYLVGGSQPLAAKVGEREITRNDFEQVYQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHH
NERNRMQSQLGEYFSTLLGDPAYVEQFRKSVLDRMVNDALLDNQAQELGLRVSDEQIRQA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHH
ILSMPQFQKDGKFDEEIFNVSLRRAGFTSDSFAEYLRGDLVRNQLVSALESTEFTLSNEV
HHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCC
KAQGELEGQQREIRTITLDTATFAKNAKVTEEEVKEYYDANKQQFVRPEQVKVSYIELSG
CCCCCCCCCCCEEEEEEEEHHHHHCCCCCCHHHHHHHHCCCHHHCCCCCCEEEEEEEECC
ESLKAQAPITDEEIQTYYNENQDKYSTQEKREVSHILIKGDEADAQAVLARLDAGEDFAT
CCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHEEEEECCCHHHHHHHHHHCCCCCHHH
VAKEDSQDIPTAKEGGSLGWIERGVIDPEFEDAAFQLVNVGDHSGLVKSAFGYHIIQLDA
HHCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCEEEEECCCCCCHHHHHCCEEEEEEEC
IEAPKTKPLAKVSADIKAFLVDEHAADAFYSMQTELAEKAFESPDSLDDAAEAVNAKVIT
CCCCCCCCHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHH
SDFFSQADAPALLANSDVLQAIYSAEVKEDGLNSDVIEIAPEHVVVVRVEESRDEMVLPL
HHHHHCCCCCEEECCHHHHHHHHHHHHHCCCCCCCHHHCCCCEEEEEEEECCCCCEECCH
EEVKASVITRLSQAKGEQKALELAKNIITALNKDDDAYLSEQGLVFTEARMITRADELAN
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHCCCCCEEHHHHHHHHHHHHHH
DVYRLQKPTADKPTYAQVMDRQGNNVIVALDDVLELDNSAMAEQVSTRLLRTQTQQDLTA
HHHHHCCCCCCCCHHHHHHHCCCCEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
TLDTLKSNTEISYPLLEQ
HHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MMDRIREGSTGLVVKIILGLIIFSFVFAGVGSYLVGGSQPLAAKVGEREITRNDFEQVYQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHH
NERNRMQSQLGEYFSTLLGDPAYVEQFRKSVLDRMVNDALLDNQAQELGLRVSDEQIRQA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHH
ILSMPQFQKDGKFDEEIFNVSLRRAGFTSDSFAEYLRGDLVRNQLVSALESTEFTLSNEV
HHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCC
KAQGELEGQQREIRTITLDTATFAKNAKVTEEEVKEYYDANKQQFVRPEQVKVSYIELSG
CCCCCCCCCCCEEEEEEEEHHHHHCCCCCCHHHHHHHHCCCHHHCCCCCCEEEEEEEECC
ESLKAQAPITDEEIQTYYNENQDKYSTQEKREVSHILIKGDEADAQAVLARLDAGEDFAT
CCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHEEEEECCCHHHHHHHHHHCCCCCHHH
VAKEDSQDIPTAKEGGSLGWIERGVIDPEFEDAAFQLVNVGDHSGLVKSAFGYHIIQLDA
HHCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCEEEEECCCCCCHHHHHCCEEEEEEEC
IEAPKTKPLAKVSADIKAFLVDEHAADAFYSMQTELAEKAFESPDSLDDAAEAVNAKVIT
CCCCCCCCHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHH
SDFFSQADAPALLANSDVLQAIYSAEVKEDGLNSDVIEIAPEHVVVVRVEESRDEMVLPL
HHHHHCCCCCEEECCHHHHHHHHHHHHHCCCCCCCHHHCCCCEEEEEEEECCCCCEECCH
EEVKASVITRLSQAKGEQKALELAKNIITALNKDDDAYLSEQGLVFTEARMITRADELAN
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHCCCCCEEHHHHHHHHHHHHHH
DVYRLQKPTADKPTYAQVMDRQGNNVIVALDDVLELDNSAMAEQVSTRLLRTQTQQDLTA
HHHHHCCCCCCCCHHHHHHHCCCCEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
TLDTLKSNTEISYPLLEQ
HHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]