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The map label for this gene is recQ [H]

Identifier: 209693836

GI number: 209693836

Start: 268514

End: 270349

Strand: Direct

Name: recQ [H]

Synonym: VSAL_I0224

Alternate gene names: 209693836

Gene position: 268514-270349 (Clockwise)

Preceding gene: 209693834

Following gene: 209693837

Centisome position: 8.08

GC content: 41.56

Gene sequence:

>1836_bases
ATGTCCAGCATTACAGTCGAGCAGCCAATGGAACAGGTATCACAGAGCCAAACTGTTTTAAGAGATGTTTTTGGTTATCA
GGAATTTCGTGTTGGACAGGAAGAAGTCATTAATGCCGTTCTTGAAGGTAAAGACAGCTTAGTTATTATGCCGACGGGTG
GCGGTAAATCACTGTGTTATCAAATTCCGGCTTTAGTGTTTGAAGGATTAACTTTAGTCATCTCGCCATTGATTTCTTTA
ATGAAAGATCAAGTGGATCAATTAAAGGCGGATGGGGTGCAAGCGGAGTGTTTAAATTCGACTATTGATCGTGACGCTCA
AGTCTCTATTTGGAACCGAGTTAATTCGGGTCAAATTAAGATGCTGTATGTGTCACCTGAGCGTGTGATGATGCGAGATT
TTATGGATCGATTAGCATCCCTAAATCTATGTATGATCGCCGTGGATGAAGCGCATTGTATTTCTCAATGGGGCCATGAT
TTCCGCCCTGAATACGCATCTCTTGGTCAAATCAAACAGCGTTTTCCTAATGTTCCGATTATGGCGCTAACGGCAACGGC
TGATGAAGCAACACGTAAAGATATATTAAGTCGTCTTTCTTTACCAAATCCCCATGAATATTTGGGCAGTTTTGATCGCC
CTAATATTCGCTATACCGTGTTAGAAAAACACAAACCAGTCAGTCAAATTGTTCGATATCTTGCAACGCAGAAAAATCAA
TGTGGTGTGATTTATTGTGGTAGCCGTAAGAAAGTCGAAATGCTGACAGAAAAACTCTGCAATAACCACATTCGAGCGGC
GTCTTATCATGCGGGTTTGGATCTTGATGAGCGAAATTATGTGCAAGAAGCATTTCAGCGAGACGATATTCAAATAGTGG
TTGCAACGGTTGCTTTTGGCATGGGGATTAATAAATCCAACGTGCGTTTTGTTGCTCATTTTGATATCCCAAAGAACATT
GAATCGTATTATCAAGAAACCGGTCGAGCAGGGCGTGATGGTTTACCTGCAGAAGCGGTGATGCTTTACGATCCTGCGGA
TATTGTTTGGTTAAGAAAATTAGTGGAAGAAAAGCCAGAAGGTCCACAAAAATTAGTTGAAAGCCATAAGTTGAATGCGA
TGACGGCTTTTGCTGAAGCGCAGACATGTCGTCGCCAAGTCCTATTAAATTATTTTGGCGAATACAATCCAAAACCTTGT
GGTAACTGTGATGTTTGTTTAGATCCCCCAAAACAATTTGATGGCACTGAAGCCGCACAAAAAGCGCTCTCTTGTGTTTA
TCGCGTAAACCAAAGCTTTGGTGTTGGTTACGTGGTGGAAGTTCTACGTGGTTTAAAGATTGCTCGTATTCGTGAGCATG
GCCATGACAAGTTATCTACTTACGGTATTGGTAAAGATAATAGCCACGAGTATTGGGTGAGCATTATTCGTCAATTGATC
CACAAAGGGCTATTAACGCAAAATATTACCCGAAACTCGACATTACAGTTAACCGAAGAGGCACGTCCGATCTTAAAAGG
TCAGGAGCCCCTAGAATTAGCGGTTCCACGTTTAGATACGGCGGCTAAAACGGCGAAATCTGAAAAATTGAATAATCGTC
AATACGATAAGCAATTGTTTGCCAAATTACGTAAGTTACGTAAATCCATTGCTGATCGTGATGATCTCCCGCCTTATGTC
GTTTTTAGTGATGCAACGTTAATGGATATGGCTGACATTACTCCGACGTCTTATGGTGAGATGCTTGCTGTTAATGGCGT
AGGGCAGAAGAAACTAGAAAAATACGCCGATCCTTTTTTAGATTTGATCGAGATGCACATTACAGGACAAGGATAA

Upstream 100 bases:

>100_bases
TAAGGATGGATGTCGAATGTGCCTAGTTTTTTCCTATTGTTCTTTTCCTCACCAATAACGATAGGTAGAATGGCCCTCCC
GCATTATTAATGAGTTTTTT

Downstream 100 bases:

>100_bases
GTCGTGAGTTTATTTTCTGTTATTGAGTTTGATAATAATGAAGGTCGTATTATTTTCGGTATCCCGCCGTTTGATTTTGA
TTCGTTTGACGTTATTGGTC

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 611; Mature: 610

Protein sequence:

>611_residues
MSSITVEQPMEQVSQSQTVLRDVFGYQEFRVGQEEVINAVLEGKDSLVIMPTGGGKSLCYQIPALVFEGLTLVISPLISL
MKDQVDQLKADGVQAECLNSTIDRDAQVSIWNRVNSGQIKMLYVSPERVMMRDFMDRLASLNLCMIAVDEAHCISQWGHD
FRPEYASLGQIKQRFPNVPIMALTATADEATRKDILSRLSLPNPHEYLGSFDRPNIRYTVLEKHKPVSQIVRYLATQKNQ
CGVIYCGSRKKVEMLTEKLCNNHIRAASYHAGLDLDERNYVQEAFQRDDIQIVVATVAFGMGINKSNVRFVAHFDIPKNI
ESYYQETGRAGRDGLPAEAVMLYDPADIVWLRKLVEEKPEGPQKLVESHKLNAMTAFAEAQTCRRQVLLNYFGEYNPKPC
GNCDVCLDPPKQFDGTEAAQKALSCVYRVNQSFGVGYVVEVLRGLKIARIREHGHDKLSTYGIGKDNSHEYWVSIIRQLI
HKGLLTQNITRNSTLQLTEEARPILKGQEPLELAVPRLDTAAKTAKSEKLNNRQYDKQLFAKLRKLRKSIADRDDLPPYV
VFSDATLMDMADITPTSYGEMLAVNGVGQKKLEKYADPFLDLIEMHITGQG

Sequences:

>Translated_611_residues
MSSITVEQPMEQVSQSQTVLRDVFGYQEFRVGQEEVINAVLEGKDSLVIMPTGGGKSLCYQIPALVFEGLTLVISPLISL
MKDQVDQLKADGVQAECLNSTIDRDAQVSIWNRVNSGQIKMLYVSPERVMMRDFMDRLASLNLCMIAVDEAHCISQWGHD
FRPEYASLGQIKQRFPNVPIMALTATADEATRKDILSRLSLPNPHEYLGSFDRPNIRYTVLEKHKPVSQIVRYLATQKNQ
CGVIYCGSRKKVEMLTEKLCNNHIRAASYHAGLDLDERNYVQEAFQRDDIQIVVATVAFGMGINKSNVRFVAHFDIPKNI
ESYYQETGRAGRDGLPAEAVMLYDPADIVWLRKLVEEKPEGPQKLVESHKLNAMTAFAEAQTCRRQVLLNYFGEYNPKPC
GNCDVCLDPPKQFDGTEAAQKALSCVYRVNQSFGVGYVVEVLRGLKIARIREHGHDKLSTYGIGKDNSHEYWVSIIRQLI
HKGLLTQNITRNSTLQLTEEARPILKGQEPLELAVPRLDTAAKTAKSEKLNNRQYDKQLFAKLRKLRKSIADRDDLPPYV
VFSDATLMDMADITPTSYGEMLAVNGVGQKKLEKYADPFLDLIEMHITGQG
>Mature_610_residues
SSITVEQPMEQVSQSQTVLRDVFGYQEFRVGQEEVINAVLEGKDSLVIMPTGGGKSLCYQIPALVFEGLTLVISPLISLM
KDQVDQLKADGVQAECLNSTIDRDAQVSIWNRVNSGQIKMLYVSPERVMMRDFMDRLASLNLCMIAVDEAHCISQWGHDF
RPEYASLGQIKQRFPNVPIMALTATADEATRKDILSRLSLPNPHEYLGSFDRPNIRYTVLEKHKPVSQIVRYLATQKNQC
GVIYCGSRKKVEMLTEKLCNNHIRAASYHAGLDLDERNYVQEAFQRDDIQIVVATVAFGMGINKSNVRFVAHFDIPKNIE
SYYQETGRAGRDGLPAEAVMLYDPADIVWLRKLVEEKPEGPQKLVESHKLNAMTAFAEAQTCRRQVLLNYFGEYNPKPCG
NCDVCLDPPKQFDGTEAAQKALSCVYRVNQSFGVGYVVEVLRGLKIARIREHGHDKLSTYGIGKDNSHEYWVSIIRQLIH
KGLLTQNITRNSTLQLTEEARPILKGQEPLELAVPRLDTAAKTAKSEKLNNRQYDKQLFAKLRKLRKSIADRDDLPPYVV
FSDATLMDMADITPTSYGEMLAVNGVGQKKLEKYADPFLDLIEMHITGQG

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=635, Percent_Identity=32.9133858267717, Blast_Score=325, Evalue=8e-89,
Organism=Homo sapiens, GI110735439, Length=560, Percent_Identity=35.8928571428571, Blast_Score=321, Evalue=1e-87,
Organism=Homo sapiens, GI169218196, Length=519, Percent_Identity=37.3795761078998, Blast_Score=320, Evalue=2e-87,
Organism=Homo sapiens, GI14591902, Length=407, Percent_Identity=41.031941031941, Blast_Score=305, Evalue=1e-82,
Organism=Homo sapiens, GI14591904, Length=407, Percent_Identity=41.031941031941, Blast_Score=305, Evalue=1e-82,
Organism=Homo sapiens, GI148612816, Length=476, Percent_Identity=35.9243697478992, Blast_Score=281, Evalue=2e-75,
Organism=Homo sapiens, GI51242943, Length=368, Percent_Identity=39.945652173913, Blast_Score=264, Evalue=2e-70,
Organism=Homo sapiens, GI51242947, Length=368, Percent_Identity=39.945652173913, Blast_Score=264, Evalue=2e-70,
Organism=Homo sapiens, GI284005309, Length=358, Percent_Identity=35.7541899441341, Blast_Score=209, Evalue=5e-54,
Organism=Homo sapiens, GI13514831, Length=369, Percent_Identity=24.390243902439, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI222352149, Length=333, Percent_Identity=24.6246246246246, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI148613856, Length=346, Percent_Identity=23.121387283237, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI38201710, Length=346, Percent_Identity=23.121387283237, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI4758138, Length=346, Percent_Identity=23.121387283237, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI48994977, Length=596, Percent_Identity=63.5906040268456, Blast_Score=818, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25145561, Length=645, Percent_Identity=32.2480620155039, Blast_Score=335, Evalue=4e-92,
Organism=Caenorhabditis elegans, GI71987993, Length=420, Percent_Identity=38.5714285714286, Blast_Score=302, Evalue=4e-82,
Organism=Caenorhabditis elegans, GI71987997, Length=420, Percent_Identity=38.5714285714286, Blast_Score=302, Evalue=4e-82,
Organism=Caenorhabditis elegans, GI32564293, Length=665, Percent_Identity=31.4285714285714, Blast_Score=296, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI17552866, Length=450, Percent_Identity=36.2222222222222, Blast_Score=266, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI17552114, Length=343, Percent_Identity=24.198250728863, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71987143, Length=384, Percent_Identity=24.7395833333333, Blast_Score=79, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI115533224, Length=357, Percent_Identity=24.6498599439776, Blast_Score=79, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17537549, Length=348, Percent_Identity=23.8505747126437, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71995724, Length=351, Percent_Identity=21.3675213675214, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17507121, Length=351, Percent_Identity=21.0826210826211, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI32565321, Length=372, Percent_Identity=23.6559139784946, Blast_Score=73, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17553716, Length=371, Percent_Identity=23.1805929919137, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508543, Length=344, Percent_Identity=22.9651162790698, Blast_Score=66, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323844, Length=467, Percent_Identity=41.3276231263383, Blast_Score=348, Evalue=1e-96,
Organism=Saccharomyces cerevisiae, GI6320224, Length=401, Percent_Identity=24.1895261845387, Blast_Score=85, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6320041, Length=348, Percent_Identity=24.4252873563218, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324217, Length=327, Percent_Identity=22.6299694189602, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322912, Length=337, Percent_Identity=24.6290801186944, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322323, Length=337, Percent_Identity=24.6290801186944, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24646066, Length=626, Percent_Identity=34.8242811501597, Blast_Score=364, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24664226, Length=459, Percent_Identity=37.037037037037, Blast_Score=289, Evalue=4e-78,
Organism=Drosophila melanogaster, GI62472181, Length=459, Percent_Identity=37.037037037037, Blast_Score=286, Evalue=3e-77,
Organism=Drosophila melanogaster, GI24664230, Length=459, Percent_Identity=37.037037037037, Blast_Score=286, Evalue=3e-77,
Organism=Drosophila melanogaster, GI21358123, Length=356, Percent_Identity=36.5168539325843, Blast_Score=216, Evalue=3e-56,
Organism=Drosophila melanogaster, GI28574962, Length=334, Percent_Identity=23.9520958083832, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24583281, Length=368, Percent_Identity=23.9130434782609, Blast_Score=77, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24583279, Length=368, Percent_Identity=23.9130434782609, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24645031, Length=355, Percent_Identity=21.4084507042254, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355075, Length=358, Percent_Identity=20.391061452514, Blast_Score=71, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 68844; Mature: 68713

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSITVEQPMEQVSQSQTVLRDVFGYQEFRVGQEEVINAVLEGKDSLVIMPTGGGKSLCY
CCCCCHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHCCCCCEEEEECCCCCHHHH
QIPALVFEGLTLVISPLISLMKDQVDQLKADGVQAECLNSTIDRDAQVSIWNRVNSGQIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEHHHCCCCCCEE
MLYVSPERVMMRDFMDRLASLNLCMIAVDEAHCISQWGHDFRPEYASLGQIKQRFPNVPI
EEEECHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCE
MALTATADEATRKDILSRLSLPNPHEYLGSFDRPNIRYTVLEKHKPVSQIVRYLATQKNQ
EEEEECCHHHHHHHHHHHCCCCCCHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCC
CGVIYCGSRKKVEMLTEKLCNNHIRAASYHAGLDLDERNYVQEAFQRDDIQIVVATVAFG
CCEEEECCCCHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHCCCCCEEEHHHHHHH
MGINKSNVRFVAHFDIPKNIESYYQETGRAGRDGLPAEAVMLYDPADIVWLRKLVEEKPE
CCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCC
GPQKLVESHKLNAMTAFAEAQTCRRQVLLNYFGEYNPKPCGNCDVCLDPPKQFDGTEAAQ
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCHHHHH
KALSCVYRVNQSFGVGYVVEVLRGLKIARIREHGHDKLSTYGIGKDNSHEYWVSIIRQLI
HHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHH
HKGLLTQNITRNSTLQLTEEARPILKGQEPLELAVPRLDTAAKTAKSEKLNNRQYDKQLF
HHHHHHCCCCCCCCEEEHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHCCHHHHHHHH
AKLRKLRKSIADRDDLPPYVVFSDATLMDMADITPTSYGEMLAVNGVGQKKLEKYADPFL
HHHHHHHHHHCCCCCCCCEEEECCCHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHH
DLIEMHITGQG
HHHHHHHCCCC
>Mature Secondary Structure 
SSITVEQPMEQVSQSQTVLRDVFGYQEFRVGQEEVINAVLEGKDSLVIMPTGGGKSLCY
CCCCHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHCCCCCEEEEECCCCCHHHH
QIPALVFEGLTLVISPLISLMKDQVDQLKADGVQAECLNSTIDRDAQVSIWNRVNSGQIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEHHHCCCCCCEE
MLYVSPERVMMRDFMDRLASLNLCMIAVDEAHCISQWGHDFRPEYASLGQIKQRFPNVPI
EEEECHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCE
MALTATADEATRKDILSRLSLPNPHEYLGSFDRPNIRYTVLEKHKPVSQIVRYLATQKNQ
EEEEECCHHHHHHHHHHHCCCCCCHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCC
CGVIYCGSRKKVEMLTEKLCNNHIRAASYHAGLDLDERNYVQEAFQRDDIQIVVATVAFG
CCEEEECCCCHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHCCCCCEEEHHHHHHH
MGINKSNVRFVAHFDIPKNIESYYQETGRAGRDGLPAEAVMLYDPADIVWLRKLVEEKPE
CCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCC
GPQKLVESHKLNAMTAFAEAQTCRRQVLLNYFGEYNPKPCGNCDVCLDPPKQFDGTEAAQ
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCHHHHH
KALSCVYRVNQSFGVGYVVEVLRGLKIARIREHGHDKLSTYGIGKDNSHEYWVSIIRQLI
HHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHH
HKGLLTQNITRNSTLQLTEEARPILKGQEPLELAVPRLDTAAKTAKSEKLNNRQYDKQLF
HHHHHHCCCCCCCCEEEHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHCCHHHHHHHH
AKLRKLRKSIADRDDLPPYVVFSDATLMDMADITPTSYGEMLAVNGVGQKKLEKYADPFL
HHHHHHHHHHCCCCCCCCEEEECCCHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHH
DLIEMHITGQG
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]