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The map label for this gene is comM [H]

Identifier: 209693672

GI number: 209693672

Start: 44867

End: 46393

Strand: Direct

Name: comM [H]

Synonym: VSAL_I0042

Alternate gene names: 209693672

Gene position: 44867-46393 (Clockwise)

Preceding gene: 209693671

Following gene: 209693673

Centisome position: 1.35

GC content: 43.75

Gene sequence:

>1527_bases
ATGGGATTAGCAATAATACACAGTCGAGCATGCGTTGGTGTTGAAGCGCCAGAGGTTACCGTTGAGGTTCATATTAGTAA
TGGAATGCCGGGTTTTAATTTAGTTGGGTTACCAGAAACAACAGTAAAAGAAGCCAAAGACAGAGTAAGAAGCGCGATAA
TAAATTCAAACTTTGAATTTCCATCAAAAAAGATCACCGTAAACTTAGCGCCTGCTGATTTACCAAAAGAAGGTGGGCGA
TTCGATCTCCCGATAGCCTTAGGTATTTTGGCTGCCTCAGATCAAATCCCAAATCATAAATTAAAAGATCATGAGTTTGT
GGGTGAGCTCGCTTTGTCTGGTGAATTACGACGAGTGAAAGGCGTGCTACCTGCGGCTCTCGCGTCATTAAAAGCCAATC
GAAGTTTAATTGTTCCTGATGAAAATGGAGATCAAGCGGCTTTGGTTGGTGCGAATGTACATAAGTCTGCGCCTCACCTT
CTATCGGTTTGTGGCTTTTTATGTGGGCAACAGCAACTGGGTTTATTTACGTCTCCGGTTATTGAGCACATTGATTTGCC
TTTAGAACGTGATCTCCAAGATATCATTGGACAGCAACAAGGTAAGCGAGCGTTAGAAATCGCAGCGGCGGGGGGACATA
ATTTATTGTATTTAGGCCCTCCAGGAACGGGGAAAACAATGTTGGCATCACGCATGAGCGACTTACTGCCTGAAATGACA
AACGATGAAGCGTTAGAGACTGCCGCAGTCGCGTCACTGACTCATCAGCATATTAATGAATCAAACTGGCGTACTCGCCC
TTTCCGTTCACCACACCATTCGAGTTCAATGGCGGCTTTGGTTGGTGGTGGTTCGATTCCCAGACCGGGTGAAATATCAT
TGGCTCACAATGGCATCTTATTTTTAGATGAAATGCCAGAGTTTGAAAGGAAAGTGTTAGATTCTTTGCGAGAGCCATTA
GAGTCGGGTGAAATTATTATTTCTCGTGTCGCTAGCAAAATGCGGTTCCCTGCCCGATTTCAATTGGTTGGTGCATTAAA
CCCGAGTCCGACTGGATACTATGAGGGGAACAATACGAGAACAAACCCTCAATTGATTTTACGTTATCTGAATCGAATAT
CCGGTCCCTTGCTTGATCGTTTTGATATGTCATTGGAGATCCCTCTTTTGCCTAAAGGGACGTTAACAGAAGGGGGGGAT
AGAGGCGAATCAAGTCTCCAAGTTAAAGAAAGGGTTAGGCTTGCTCGTGTGAAAATGCTAGAGAGAAGTGGGAAAATTAA
TGCATTATTGAGTAGCCGAGAGGTTGAAACTTATTGCCCACTAGAAAAGGAAGATGCGGTTTTTCTAGAAGATACACTAT
ATCGATTGGGGCTTTCTATTCGTGCGTATCATCGAATCATTAAAGTGGCCAGAACCATTGCTGATTTATCTGGATCAGAG
AACATTCAGCGTATCCATTTGGGTGAGGCCGTTGGTTACCGTGCTATGGATAGATTATTGAAACAATTAAGTGCTCAAGC
GGTGTAG

Upstream 100 bases:

>100_bases
ACTCTCATTTTATTCACAATTCTCGTTCATTTAGCGCTTATATATAACAAATCAATGAAAGACGTTGAGATTATTGGGTT
ATAAATAATTGGGAATAAGA

Downstream 100 bases:

>100_bases
TGTCTTTTTCTTAAGATGAGAGAAAATAGGGATAACAAAAAAAAGTCAGTCTTGGTATTATTAGCGCAATTTTTATCCCG
CTAATCAATGAAGATTTTTA

Product: competence protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 508; Mature: 507

Protein sequence:

>508_residues
MGLAIIHSRACVGVEAPEVTVEVHISNGMPGFNLVGLPETTVKEAKDRVRSAIINSNFEFPSKKITVNLAPADLPKEGGR
FDLPIALGILAASDQIPNHKLKDHEFVGELALSGELRRVKGVLPAALASLKANRSLIVPDENGDQAALVGANVHKSAPHL
LSVCGFLCGQQQLGLFTSPVIEHIDLPLERDLQDIIGQQQGKRALEIAAAGGHNLLYLGPPGTGKTMLASRMSDLLPEMT
NDEALETAAVASLTHQHINESNWRTRPFRSPHHSSSMAALVGGGSIPRPGEISLAHNGILFLDEMPEFERKVLDSLREPL
ESGEIIISRVASKMRFPARFQLVGALNPSPTGYYEGNNTRTNPQLILRYLNRISGPLLDRFDMSLEIPLLPKGTLTEGGD
RGESSLQVKERVRLARVKMLERSGKINALLSSREVETYCPLEKEDAVFLEDTLYRLGLSIRAYHRIIKVARTIADLSGSE
NIQRIHLGEAVGYRAMDRLLKQLSAQAV

Sequences:

>Translated_508_residues
MGLAIIHSRACVGVEAPEVTVEVHISNGMPGFNLVGLPETTVKEAKDRVRSAIINSNFEFPSKKITVNLAPADLPKEGGR
FDLPIALGILAASDQIPNHKLKDHEFVGELALSGELRRVKGVLPAALASLKANRSLIVPDENGDQAALVGANVHKSAPHL
LSVCGFLCGQQQLGLFTSPVIEHIDLPLERDLQDIIGQQQGKRALEIAAAGGHNLLYLGPPGTGKTMLASRMSDLLPEMT
NDEALETAAVASLTHQHINESNWRTRPFRSPHHSSSMAALVGGGSIPRPGEISLAHNGILFLDEMPEFERKVLDSLREPL
ESGEIIISRVASKMRFPARFQLVGALNPSPTGYYEGNNTRTNPQLILRYLNRISGPLLDRFDMSLEIPLLPKGTLTEGGD
RGESSLQVKERVRLARVKMLERSGKINALLSSREVETYCPLEKEDAVFLEDTLYRLGLSIRAYHRIIKVARTIADLSGSE
NIQRIHLGEAVGYRAMDRLLKQLSAQAV
>Mature_507_residues
GLAIIHSRACVGVEAPEVTVEVHISNGMPGFNLVGLPETTVKEAKDRVRSAIINSNFEFPSKKITVNLAPADLPKEGGRF
DLPIALGILAASDQIPNHKLKDHEFVGELALSGELRRVKGVLPAALASLKANRSLIVPDENGDQAALVGANVHKSAPHLL
SVCGFLCGQQQLGLFTSPVIEHIDLPLERDLQDIIGQQQGKRALEIAAAGGHNLLYLGPPGTGKTMLASRMSDLLPEMTN
DEALETAAVASLTHQHINESNWRTRPFRSPHHSSSMAALVGGGSIPRPGEISLAHNGILFLDEMPEFERKVLDSLREPLE
SGEIIISRVASKMRFPARFQLVGALNPSPTGYYEGNNTRTNPQLILRYLNRISGPLLDRFDMSLEIPLLPKGTLTEGGDR
GESSLQVKERVRLARVKMLERSGKINALLSSREVETYCPLEKEDAVFLEDTLYRLGLSIRAYHRIIKVARTIADLSGSEN
IQRIHLGEAVGYRAMDRLLKQLSAQAV

Specific function: Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step [H]

COG id: COG0606

COG function: function code O; Predicted ATPase with chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693202, Length=503, Percent_Identity=59.8409542743539, Blast_Score=619, Evalue=1e-178,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR004482
- InterPro:   IPR000523
- InterPro:   IPR020568 [H]

Pfam domain/function: PF01078 Mg_chelatase [H]

EC number: NA

Molecular weight: Translated: 55412; Mature: 55280

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00676 SIGMA54_INTERACT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLAIIHSRACVGVEAPEVTVEVHISNGMPGFNLVGLPETTVKEAKDRVRSAIINSNFEF
CCEEEEECCCEECCCCCCEEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCC
PSKKITVNLAPADLPKEGGRFDLPIALGILAASDQIPNHKLKDHEFVGELALSGELRRVK
CCCEEEEEECCCCCCCCCCCCCCHHHHEEEECCCCCCCCCCCCHHHHHHHHHCCHHHHHH
GVLPAALASLKANRSLIVPDENGDQAALVGANVHKSAPHLLSVCGFLCGQQQLGLFTSPV
HHHHHHHHHHHCCCEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCHHCCCHHHHH
IEHIDLPLERDLQDIIGQQQGKRALEIAAAGGHNLLYLGPPGTGKTMLASRMSDLLPEMT
HHHCCCCHHHHHHHHHCHHCCCCEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHCCCCC
NDEALETAAVASLTHQHINESNWRTRPFRSPHHSSSMAALVGGGSIPRPGEISLAHNGIL
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEECCCEE
FLDEMPEFERKVLDSLREPLESGEIIISRVASKMRFPARFQLVGALNPSPTGYYEGNNTR
EECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCEECCCCCC
TNPQLILRYLNRISGPLLDRFDMSLEIPLLPKGTLTEGGDRGESSLQVKERVRLARVKML
CCHHHHHHHHHHHCCHHHHHCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ERSGKINALLSSREVETYCPLEKEDAVFLEDTLYRLGLSIRAYHRIIKVARTIADLSGSE
HHCCCEEEECCCCCCHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCC
NIQRIHLGEAVGYRAMDRLLKQLSAQAV
CCEEEECCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GLAIIHSRACVGVEAPEVTVEVHISNGMPGFNLVGLPETTVKEAKDRVRSAIINSNFEF
CEEEEECCCEECCCCCCEEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCC
PSKKITVNLAPADLPKEGGRFDLPIALGILAASDQIPNHKLKDHEFVGELALSGELRRVK
CCCEEEEEECCCCCCCCCCCCCCHHHHEEEECCCCCCCCCCCCHHHHHHHHHCCHHHHHH
GVLPAALASLKANRSLIVPDENGDQAALVGANVHKSAPHLLSVCGFLCGQQQLGLFTSPV
HHHHHHHHHHHCCCEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCHHCCCHHHHH
IEHIDLPLERDLQDIIGQQQGKRALEIAAAGGHNLLYLGPPGTGKTMLASRMSDLLPEMT
HHHCCCCHHHHHHHHHCHHCCCCEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHCCCCC
NDEALETAAVASLTHQHINESNWRTRPFRSPHHSSSMAALVGGGSIPRPGEISLAHNGIL
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEECCCEE
FLDEMPEFERKVLDSLREPLESGEIIISRVASKMRFPARFQLVGALNPSPTGYYEGNNTR
EECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCEECCCCCC
TNPQLILRYLNRISGPLLDRFDMSLEIPLLPKGTLTEGGDRGESSLQVKERVRLARVKML
CCHHHHHHHHHHHCCHHHHHCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ERSGKINALLSSREVETYCPLEKEDAVFLEDTLYRLGLSIRAYHRIIKVARTIADLSGSE
HHCCCEEEECCCCCCHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCC
NIQRIHLGEAVGYRAMDRLLKQLSAQAV
CCEEEECCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9457884 [H]