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The map label for this gene is trmD [H]

Identifier: 209554633

GI number: 209554633

Start: 795953

End: 796639

Strand: Reverse

Name: trmD [H]

Synonym: UUR10_0664

Alternate gene names: 209554633

Gene position: 796639-795953 (Counterclockwise)

Preceding gene: 209554491

Following gene: 209554487

Centisome position: 91.1

GC content: 28.24

Gene sequence:

>687_bases
ATGAAAATATCAATTTTATCTTTATTTCCTGAATTATATGAAACATGGATAAACCATTCTATTATTAGTAATGCTATTAA
AAATAATCAAGTTACGATAGAAATTATTAATTTTCGTTTATACACAAATGATAAACACAAAAAAGTTGATGATTATCAAT
ATGGTGGTGGAGCTGGTATGGTTTTAATGATCGAACCAATTGTATCTGCCATTCGTGCGATTCGTACACCTAATTCATAT
GTGATTTTAACAACACCAAAAGGTCAAGTTTTTAATCAAGAATTAGCTAACGAATTTGTTAGTAAATATGATCATATTAT
TATCATTGCTGGTCATTATGAAGGTTTTGATGAACGTATTAATTATTACGTTGATGCCCAATATAGTATTGGTGATTTTG
TTTTAACAGGAGGAGAATTACCTAGTATGGTAATTTCTGATGCTGTTATTCGATTATTAGATGGTGTTATTTCTTCATCT
AGTTTAGAAAGTGAATCATTTAATAACTATTTATTAGATTATCCTGTTTATACACGTCCTGTTGTTTTTGAAGGACATCA
AGTACCAGATGTACTTTTATCTGGTCATCACAAAAACATTGCTGATTTTCGTAAACAGCAACAAGAGATGATTACTAAAA
AGAATCGTCCTGATTTATATCAAAAATATTTAAATAGCAAAAAGTAG

Upstream 100 bases:

>100_bases
CTTATCACAAGAAGGTATTTGAAAAGAATTCATTGCTTTAAAAGATGCAAACAAAAAACGTAAAGCAGCTTTAGCTAAGG
CTAAATAATTCATAACATAG

Downstream 100 bases:

>100_bases
GTGTAAAAAAATGGCTTTATTTAAAATTAACAAAGGCGAAATTATGAATTTTGTTAATTCGACACAATTAAAAACAGATA
TTCCTAGTTTTGATTCTGGT

Product: tRNA (guanine-N(1)-)-methyltransferase

Products: NA

Alternate protein names: M1G-methyltransferase; tRNA [GM37] methyltransferase [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MKISILSLFPELYETWINHSIISNAIKNNQVTIEIINFRLYTNDKHKKVDDYQYGGGAGMVLMIEPIVSAIRAIRTPNSY
VILTTPKGQVFNQELANEFVSKYDHIIIIAGHYEGFDERINYYVDAQYSIGDFVLTGGELPSMVISDAVIRLLDGVISSS
SLESESFNNYLLDYPVYTRPVVFEGHQVPDVLLSGHHKNIADFRKQQQEMITKKNRPDLYQKYLNSKK

Sequences:

>Translated_228_residues
MKISILSLFPELYETWINHSIISNAIKNNQVTIEIINFRLYTNDKHKKVDDYQYGGGAGMVLMIEPIVSAIRAIRTPNSY
VILTTPKGQVFNQELANEFVSKYDHIIIIAGHYEGFDERINYYVDAQYSIGDFVLTGGELPSMVISDAVIRLLDGVISSS
SLESESFNNYLLDYPVYTRPVVFEGHQVPDVLLSGHHKNIADFRKQQQEMITKKNRPDLYQKYLNSKK
>Mature_228_residues
MKISILSLFPELYETWINHSIISNAIKNNQVTIEIINFRLYTNDKHKKVDDYQYGGGAGMVLMIEPIVSAIRAIRTPNSY
VILTTPKGQVFNQELANEFVSKYDHIIIIAGHYEGFDERINYYVDAQYSIGDFVLTGGELPSMVISDAVIRLLDGVISSS
SLESESFNNYLLDYPVYTRPVVFEGHQVPDVLLSGHHKNIADFRKQQQEMITKKNRPDLYQKYLNSKK

Specific function: Specifically methylates guanosine-37 in various tRNAs [H]

COG id: COG0336

COG function: function code J; tRNA-(guanine-N1)-methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase trmD family [H]

Homologues:

Organism=Escherichia coli, GI1788959, Length=226, Percent_Identity=40.2654867256637, Blast_Score=171, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016009
- InterPro:   IPR002649
- InterPro:   IPR023148 [H]

Pfam domain/function: PF01746 tRNA_m1G_MT [H]

EC number: =2.1.1.31 [H]

Molecular weight: Translated: 26088; Mature: 26088

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISILSLFPELYETWINHSIISNAIKNNQVTIEIINFRLYTNDKHKKVDDYQYGGGAGM
CEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCCCCEEECCCCCE
VLMIEPIVSAIRAIRTPNSYVILTTPKGQVFNQELANEFVSKYDHIIIIAGHYEGFDERI
EEEHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCEEEEEEECCCCHHHHE
NYYVDAQYSIGDFVLTGGELPSMVISDAVIRLLDGVISSSSLESESFNNYLLDYPVYTRP
EEEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCC
VVFEGHQVPDVLLSGHHKNIADFRKQQQEMITKKNRPDLYQKYLNSKK
EEECCCCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCC
>Mature Secondary Structure
MKISILSLFPELYETWINHSIISNAIKNNQVTIEIINFRLYTNDKHKKVDDYQYGGGAGM
CEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCCCCEEECCCCCE
VLMIEPIVSAIRAIRTPNSYVILTTPKGQVFNQELANEFVSKYDHIIIIAGHYEGFDERI
EEEHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCEEEEEEECCCCHHHHE
NYYVDAQYSIGDFVLTGGELPSMVISDAVIRLLDGVISSSSLESESFNNYLLDYPVYTRP
EEEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCC
VVFEGHQVPDVLLSGHHKNIADFRKQQQEMITKKNRPDLYQKYLNSKK
EEECCCCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA