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The map label for this gene is ung [H]

Identifier: 209554544

GI number: 209554544

Start: 765404

End: 766042

Strand: Reverse

Name: ung [H]

Synonym: UUR10_0639

Alternate gene names: 209554544

Gene position: 766042-765404 (Counterclockwise)

Preceding gene: 209554079

Following gene: 209554446

Centisome position: 87.6

GC content: 27.7

Gene sequence:

>639_bases
ATGAAATGAAAAGAATTTATAATTAATCAAACCAAACAAGATTATTTAAGAAATATTATTCAAAAAGTTAATACAATCGA
AAATCATCAAGTTGTTTATCCTTTAAAAAAACAACGATTTCGATGTTTTAACTTTTTTGATATTGAACAAACTAAAGTTG
TTATTTTAGGTCAAGACCCATACCACACCCCAAAAATGGCTAATGGTTTATGTTTTAGTGTTGATTTAGGTAATAATTTA
CCTGGATCATTAGTTAATATTTTCAAAGCCTTAGAGTATGATTTGCAAATAAAAAGAACAAATCCTGATTTATCTGATTG
AGCAAAACAAGGCGTTTTATTGTTAAATACTGTTTTAACTGTTAATGCTCATCAAGCTAATTCACATAAGGATTTTGGGT
ATGATCAACTAATTAAAAATGCGTTTATTGAACTAAAAAAACAAAAACATGTTGTTTATTTGTTGTGAGGAAAACAAGCG
ATGAGCTATATTGATTTAATTGATAAAGATCACAATTTAATTTTATGTGCTCCCCATCCTTCACCACTAAGCGCGCATCG
TGGTTTTTTAACTTGCAAGCATTTTAGTGCATGTAATGATTATTTAATTAAACATTTTCGCACTCCAATAAAATGGTAA

Upstream 100 bases:

>100_bases
ATATTCATGATTTAAGTAGTTTTGAATCTGCTAAAAATAATTTAAAGAAATATCTTTTTGATCTTAATGATATTAAAAGT
GTAAACGTTAACTATAGTAA

Downstream 100 bases:

>100_bases
AATTAAATAATTAGTGAGGTGAATCTGTGACAAACATAACAAGCGTATTGCATGCAACAAATACTTCACAAGGTAATGGA
ATTAATTCATGACAATCAAT

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MKWKEFIINQTKQDYLRNIIQKVNTIENHQVVYPLKKQRFRCFNFFDIEQTKVVILGQDPYHTPKMANGLCFSVDLGNNL
PGSLVNIFKALEYDLQIKRTNPDLSDWAKQGVLLLNTVLTVNAHQANSHKDFGYDQLIKNAFIELKKQKHVVYLLWGKQA
MSYIDLIDKDHNLILCAPHPSPLSAHRGFLTCKHFSACNDYLIKHFRTPIKW

Sequences:

>Translated_212_residues
MK*KEFIINQTKQDYLRNIIQKVNTIENHQVVYPLKKQRFRCFNFFDIEQTKVVILGQDPYHTPKMANGLCFSVDLGNNL
PGSLVNIFKALEYDLQIKRTNPDLSD*AKQGVLLLNTVLTVNAHQANSHKDFGYDQLIKNAFIELKKQKHVVYLL*GKQA
MSYIDLIDKDHNLILCAPHPSPLSAHRGFLTCKHFSACNDYLIKHFRTPIKW
>Mature_212_residues
MK*KEFIINQTKQDYLRNIIQKVNTIENHQVVYPLKKQRFRCFNFFDIEQTKVVILGQDPYHTPKMANGLCFSVDLGNNL
PGSLVNIFKALEYDLQIKRTNPDLSD*AKQGVLLLNTVLTVNAHQANSHKDFGYDQLIKNAFIELKKQKHVVYLL*GKQA
MSYIDLIDKDHNLILCAPHPSPLSAHRGFLTCKHFSACNDYLIKHFRTPIKW

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI19718751, Length=212, Percent_Identity=42.9245283018868, Blast_Score=155, Evalue=2e-38,
Organism=Homo sapiens, GI6224979, Length=212, Percent_Identity=42.9245283018868, Blast_Score=155, Evalue=2e-38,
Organism=Escherichia coli, GI1788934, Length=212, Percent_Identity=42.9245283018868, Blast_Score=161, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17556304, Length=214, Percent_Identity=40.1869158878505, Blast_Score=135, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6323620, Length=221, Percent_Identity=33.9366515837104, Blast_Score=108, Evalue=6e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 24128; Mature: 24128

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEFIINQTKQDYLRNIIQKVNTIENHQVVYPLKKQRFRCFNFFDIEQTKVVILGQDPY
CCCCCEECCCHHHHHHHHHHHHHCCCCCEEEECHHHCCEEECEEEECCCEEEEEECCCCC
HTPKMANGLCFSVDLGNNLPGSLVNIFKALEYDLQIKRTNPDLSDAKQGVLLLNTVLTVN
CCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCEEEEECCCCHHHHHCCEEEEEEEEEEE
AHQANSHKDFGYDQLIKNAFIELKKQKHVVYLLGKQAMSYIDLIDKDHNLILCAPHPSPL
CCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHCCCCCEEEECCCCCCC
SAHRGFLTCKHFSACNDYLIKHFRTPIKW
CCCCCEEEEHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKKEFIINQTKQDYLRNIIQKVNTIENHQVVYPLKKQRFRCFNFFDIEQTKVVILGQDPY
CCCCCEECCCHHHHHHHHHHHHHCCCCCEEEECHHHCCEEECEEEECCCEEEEEECCCCC
HTPKMANGLCFSVDLGNNLPGSLVNIFKALEYDLQIKRTNPDLSDAKQGVLLLNTVLTVN
CCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCEEEEECCCCHHHHHCCEEEEEEEEEEE
AHQANSHKDFGYDQLIKNAFIELKKQKHVVYLLGKQAMSYIDLIDKDHNLILCAPHPSPL
CCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHCCCCCEEEECCCCCCC
SAHRGFLTCKHFSACNDYLIKHFRTPIKW
CCCCCEEEEHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA