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The map label for this gene is csd [H]

Identifier: 209554308

GI number: 209554308

Start: 538600

End: 539808

Strand: Reverse

Name: csd [H]

Synonym: UUR10_0489

Alternate gene names: 209554308

Gene position: 539808-538600 (Counterclockwise)

Preceding gene: 209554008

Following gene: 209554191

Centisome position: 61.73

GC content: 29.03

Gene sequence:

>1209_bases
ATGGATAATTACAAACAATTTTTTCCTTGATTTAAAAATAATAAAGATGTTGTTTATTTAGATTCAAGCGCAACTTCACT
AAAACCACAAGTAGTAGTTGATGCAATTGTTGATTATTATACAAAATATTCAACTAACCCCCATAATAGTGATTCAAATT
TTGCTTTTCATCCACATAAAATCATGTATGAAACTAGGGCTAATGTAGCTAAATTTATTAACGCTGACTTTGAAGAAATT
GTTTTTACAAGTGGGGCGACAGAGTCTTTGAATTTAATTGCTAATGGCCTAAGACCATATTTAAAAAAAGATGATGAAAT
TGTTTTAACTTACGTTGAACACGCTTCTAATTTATTGCCGTGATATAAACTTCGTGATGATCTTGGTATTAAAATTGTTT
TTGCTAATCAAAAAAACCAATTTCCTCAACTTAGTGATTTTTTAAATGCAATTTCACCAAAAACTAAAATTGTCTCTTTT
GCATCAGGCGGCAATTTAATTGGCAATATTTTAGATGAAAATGTCATTATTAAACATATCAAACAATTAAACCCTAACAT
TTTAGTATGTGTTGATGCAACGCAAAGTGTTCAACATCGTATGTTTGATGTTGAAAAATGTCAAAGTGATTTTATGGTTT
TTTCAGCTCATAAACTACTTGGTCCAACAGGGATTGGTGTAGCTTATATTAAAAATGAGTGGATTAAAAAATTACAACCA
CTAAAATATGGTGGCGGCATGAATTTTAGTATTGATTTAGATAGTTATCAACTATATGATGATTATATGAAATTTGAAGG
TGGCACTCCCCATGTAGCTGGTTTTTATGGTTTTAATGCAGCTTTAAAATTCTTAATGGATATTGGTTATGAGAAAATCC
ATGATCATGAACTAAAAATTACTCAATACGCACGCGAACAATTAGCTCTAATTCCCCAAATTAAAACATATGTTCAAGAT
CCAACATCGAGTACAATAACTTTTAGTTATGAAGGTGTTTTTTGTCAAGATTTTGCTAGTTATTTAGGAACAAAAAATAT
TATTGTTCGAAGTGGATTATCATGTGCAAAAATTATTAATAACATCATTCAAACAGAATGTGCTATTCGTGCTTCGTTTT
ATATATATAATGATTTTAGTGATGTTGATAAACTAGTTCAAGCAATTAAAGAGTATCAAAAAGGAGATGAATTAAATGGC
ATCTTATAA

Upstream 100 bases:

>100_bases
AAGCTTTAAAAAATATTGAGGGTATTGTTTTTTGCGAATTAAGTCATTACTAATGTCGTGAATAATTAATGCTATTTTTA
AAAATATGTAGGGGTGTGTT

Downstream 100 bases:

>100_bases
TATCAATGACAATCTAACATTGCGTAGTATTATTATGGAACATTACGAACGGCCTAAAAATAAAGTTTGCTTTGTACAAA
ATGAAACTGATTATTTATCA

Product: probable cysteine desulfurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MDNYKQFFPWFKNNKDVVYLDSSATSLKPQVVVDAIVDYYTKYSTNPHNSDSNFAFHPHKIMYETRANVAKFINADFEEI
VFTSGATESLNLIANGLRPYLKKDDEIVLTYVEHASNLLPWYKLRDDLGIKIVFANQKNQFPQLSDFLNAISPKTKIVSF
ASGGNLIGNILDENVIIKHIKQLNPNILVCVDATQSVQHRMFDVEKCQSDFMVFSAHKLLGPTGIGVAYIKNEWIKKLQP
LKYGGGMNFSIDLDSYQLYDDYMKFEGGTPHVAGFYGFNAALKFLMDIGYEKIHDHELKITQYAREQLALIPQIKTYVQD
PTSSTITFSYEGVFCQDFASYLGTKNIIVRSGLSCAKIINNIIQTECAIRASFYIYNDFSDVDKLVQAIKEYQKGDELNG
IL

Sequences:

>Translated_402_residues
MDNYKQFFP*FKNNKDVVYLDSSATSLKPQVVVDAIVDYYTKYSTNPHNSDSNFAFHPHKIMYETRANVAKFINADFEEI
VFTSGATESLNLIANGLRPYLKKDDEIVLTYVEHASNLLP*YKLRDDLGIKIVFANQKNQFPQLSDFLNAISPKTKIVSF
ASGGNLIGNILDENVIIKHIKQLNPNILVCVDATQSVQHRMFDVEKCQSDFMVFSAHKLLGPTGIGVAYIKNEWIKKLQP
LKYGGGMNFSIDLDSYQLYDDYMKFEGGTPHVAGFYGFNAALKFLMDIGYEKIHDHELKITQYAREQLALIPQIKTYVQD
PTSSTITFSYEGVFCQDFASYLGTKNIIVRSGLSCAKIINNIIQTECAIRASFYIYNDFSDVDKLVQAIKEYQKGDELNG
IL
>Mature_402_residues
MDNYKQFFP*FKNNKDVVYLDSSATSLKPQVVVDAIVDYYTKYSTNPHNSDSNFAFHPHKIMYETRANVAKFINADFEEI
VFTSGATESLNLIANGLRPYLKKDDEIVLTYVEHASNLLP*YKLRDDLGIKIVFANQKNQFPQLSDFLNAISPKTKIVSF
ASGGNLIGNILDENVIIKHIKQLNPNILVCVDATQSVQHRMFDVEKCQSDFMVFSAHKLLGPTGIGVAYIKNEWIKKLQP
LKYGGGMNFSIDLDSYQLYDDYMKFEGGTPHVAGFYGFNAALKFLMDIGYEKIHDHELKITQYAREQLALIPQIKTYVQD
PTSSTITFSYEGVFCQDFASYLGTKNIIVRSGLSCAKIINNIIQTECAIRASFYIYNDFSDVDKLVQAIKEYQKGDELNG
IL

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=239, Percent_Identity=31.3807531380753, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI156713448, Length=259, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=7e-16,
Organism=Escherichia coli, GI1789175, Length=392, Percent_Identity=33.4183673469388, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1787970, Length=404, Percent_Identity=29.7029702970297, Blast_Score=191, Evalue=6e-50,
Organism=Escherichia coli, GI48994898, Length=232, Percent_Identity=32.3275862068966, Blast_Score=105, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI25143064, Length=233, Percent_Identity=29.6137339055794, Blast_Score=97, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6319831, Length=235, Percent_Identity=34.0425531914894, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI20129463, Length=233, Percent_Identity=32.1888412017167, Blast_Score=112, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 45296; Mature: 45296

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNYKQFFPFKNNKDVVYLDSSATSLKPQVVVDAIVDYYTKYSTNPHNSDSNFAFHPHKI
CCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCHHH
MYETRANVAKFINADFEEIVFTSGATESLNLIANGLRPYLKKDDEIVLTYVEHASNLLPY
HHHHHHHHHHHHCCCHHHHEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEEHHHCCCCCE
KLRDDLGIKIVFANQKNQFPQLSDFLNAISPKTKIVSFASGGNLIGNILDENVIIKHIKQ
EECCCCCEEEEEECCCCCCCCHHHHHHHCCCCCEEEEEECCCCHHHHHHCCHHHHHHHHH
LNPNILVCVDATQSVQHRMFDVEKCQSDFMVFSAHKLLGPTGIGVAYIKNEWIKKLQPLK
CCCCEEEEECCHHHHHHHHHHHHHHHCCCEEEEHHHHCCCCCCCHHHHHHHHHHHCCCCC
YGGGMNFSIDLDSYQLYDDYMKFEGGTPHVAGFYGFNAALKFLMDIGYEKIHDHELKITQ
CCCCCEEEEECCCHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHCCHHHHCCCCHHHHH
YAREQLALIPQIKTYVQDPTSSTITFSYEGVFCQDFASYLGTKNIIVRSGLSCAKIINNI
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEHHHHHHHCCCCCEEEECCCHHHHHHHHH
IQTECAIRASFYIYNDFSDVDKLVQAIKEYQKGDELNGIL
HHHHHHEEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MDNYKQFFPFKNNKDVVYLDSSATSLKPQVVVDAIVDYYTKYSTNPHNSDSNFAFHPHKI
CCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCHHH
MYETRANVAKFINADFEEIVFTSGATESLNLIANGLRPYLKKDDEIVLTYVEHASNLLPY
HHHHHHHHHHHHCCCHHHHEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEEHHHCCCCCE
KLRDDLGIKIVFANQKNQFPQLSDFLNAISPKTKIVSFASGGNLIGNILDENVIIKHIKQ
EECCCCCEEEEEECCCCCCCCHHHHHHHCCCCCEEEEEECCCCHHHHHHCCHHHHHHHHH
LNPNILVCVDATQSVQHRMFDVEKCQSDFMVFSAHKLLGPTGIGVAYIKNEWIKKLQPLK
CCCCEEEEECCHHHHHHHHHHHHHHHCCCEEEEHHHHCCCCCCCHHHHHHHHHHHCCCCC
YGGGMNFSIDLDSYQLYDDYMKFEGGTPHVAGFYGFNAALKFLMDIGYEKIHDHELKITQ
CCCCCEEEEECCCHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHCCHHHHCCCCHHHHH
YAREQLALIPQIKTYVQDPTSSTITFSYEGVFCQDFASYLGTKNIIVRSGLSCAKIINNI
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEHHHHHHHCCCCCEEEECCCHHHHHHHHH
IQTECAIRASFYIYNDFSDVDKLVQAIKEYQKGDELNGIL
HHHHHHEEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11048724 [H]