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The map label for this gene is cdsA [H]

Identifier: 209554263

GI number: 209554263

Start: 713768

End: 714913

Strand: Reverse

Name: cdsA [H]

Synonym: UUR10_0593

Alternate gene names: 209554263

Gene position: 714913-713768 (Counterclockwise)

Preceding gene: 209554340

Following gene: 209554147

Centisome position: 81.75

GC content: 24.0

Gene sequence:

>1146_bases
ATGATTAGTGTTAATAAAATCAATGAAAAAACAAAAACCACTTTTTTTAAGCGGTTTTATTCATCGATTTTTATTTTTTT
GTATTTATTAATTTATTTTGTTTTAGCATTATTATCAGATCGTAATTATAGTTGAACACCTTTAATTGATCATTTATATA
TTCAACAAGCAATCGCAATTGTTTTATTAGTATGATTATTACCATTAGTATGGATTGCCTCGTATGAAATGAACAAAGTT
ATTTTTGATAATCATAAAATAACAAGAATAACCTTAACAATTATTTTCAATATTTGTGTTTATGCACCAACAATTTCTTA
TTTTATTTATCAGTATGAATTTTTAGATGTTAATTATTTAATGACTATAAATTATCATTACATGATTAAATTGTTTGGTA
CATGTTTGGGTTGTTCGTATTTTGTTGCTTTAGTTATTTTGTTTTTCCTTTTAGCATTTTTAAAAAAAGTTAATTTTAAA
AACTGCTTATATACTATTTTAATTTTCACTTTCTTAATTGGTTTTTTTATAGGGTTACTTTACTTTACGTTCATTAGAAG
TTGAATTACTTCATTACTGCTAATGTTGATTGTTTTTTTAAGTGATACATTTGCTTATGTTGGTGGTGTTTTATTTGGCA
AAACTAAATTAGCACCAAAAACAAGTCCTAACAAAACAGTTGAAGGTTTAATTTTTGGTTTAGTGATTGCAACAATTGTT
ATTATGTTAATAATTTTTGGTTTATCATATGTGCCAATCAAACCAAAAAATGACATGATATTAAAATCACAAAACGTGCT
ATATAATATTTTCGGTTTAGATTTTTCTAATTCAAATAAAACAAATTTAACACTTCATAAACAAGTATTATGATGAATAT
GTACAACAGTTGCTTTTTTATTTTTAAGTTTAATAAGCACTATTGGTGATCTAGTATTTAGTGCGACAAAACGTAATTAT
GATACCAAAGATTATAGTAATTTAATTCCAGGTCATGGTGGATTATTAGATCGAATTGATTCGCATTCTTTTGTAATAAC
AATTATGTTCATTTTCACACTAGTTATTACAGGTAGTTTACAAGATGAAAACTTATTTCCAAGCATTCAAAAAGTTTTCG
TTGAGATTAGTAGTTCTATAGTTTAA

Upstream 100 bases:

>100_bases
CAAACAGAATTAGATAATCTAACAAAAGAATTAAATAAGGAAATTGAAGCAGTTGTAAGTCATAAAGAAAAAGACATAAT
GACTGTTTAATTATTTAAAA

Downstream 100 bases:

>100_bases
AATTATTAATTATTGATTTGATTAATGGTTGTGTGTTAGTGTATATACTAATACCAATCATTTTTTCATTTGTTTTTAAA
TTAAGAAAAATTTTAATTAC

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MISVNKINEKTKTTFFKRFYSSIFIFLYLLIYFVLALLSDRNYSWTPLIDHLYIQQAIAIVLLVWLLPLVWIASYEMNKV
IFDNHKITRITLTIIFNICVYAPTISYFIYQYEFLDVNYLMTINYHYMIKLFGTCLGCSYFVALVILFFLLAFLKKVNFK
NCLYTILIFTFLIGFFIGLLYFTFIRSWITSLLLMLIVFLSDTFAYVGGVLFGKTKLAPKTSPNKTVEGLIFGLVIATIV
IMLIIFGLSYVPIKPKNDMILKSQNVLYNIFGLDFSNSNKTNLTLHKQVLWWICTTVAFLFLSLISTIGDLVFSATKRNY
DTKDYSNLIPGHGGLLDRIDSHSFVITIMFIFTLVITGSLQDENLFPSIQKVFVEISSSIV

Sequences:

>Translated_381_residues
MISVNKINEKTKTTFFKRFYSSIFIFLYLLIYFVLALLSDRNYS*TPLIDHLYIQQAIAIVLLV*LLPLVWIASYEMNKV
IFDNHKITRITLTIIFNICVYAPTISYFIYQYEFLDVNYLMTINYHYMIKLFGTCLGCSYFVALVILFFLLAFLKKVNFK
NCLYTILIFTFLIGFFIGLLYFTFIRS*ITSLLLMLIVFLSDTFAYVGGVLFGKTKLAPKTSPNKTVEGLIFGLVIATIV
IMLIIFGLSYVPIKPKNDMILKSQNVLYNIFGLDFSNSNKTNLTLHKQVL**ICTTVAFLFLSLISTIGDLVFSATKRNY
DTKDYSNLIPGHGGLLDRIDSHSFVITIMFIFTLVITGSLQDENLFPSIQKVFVEISSSIV
>Mature_381_residues
MISVNKINEKTKTTFFKRFYSSIFIFLYLLIYFVLALLSDRNYS*TPLIDHLYIQQAIAIVLLV*LLPLVWIASYEMNKV
IFDNHKITRITLTIIFNICVYAPTISYFIYQYEFLDVNYLMTINYHYMIKLFGTCLGCSYFVALVILFFLLAFLKKVNFK
NCLYTILIFTFLIGFFIGLLYFTFIRS*ITSLLLMLIVFLSDTFAYVGGVLFGKTKLAPKTSPNKTVEGLIFGLVIATIV
IMLIIFGLSYVPIKPKNDMILKSQNVLYNIFGLDFSNSNKTNLTLHKQVL**ICTTVAFLFLSLISTIGDLVFSATKRNY
DTKDYSNLIPGHGGLLDRIDSHSFVITIMFIFTLVITGSLQDENLFPSIQKVFVEISSSIV

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Homo sapiens, GI20143480, Length=174, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 42950; Mature: 42950

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVNKINEKTKTTFFKRFYSSIFIFLYLLIYFVLALLSDRNYSTPLIDHLYIQQAIAIV
CCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LLVLLPLVWIASYEMNKVIFDNHKITRITLTIIFNICVYAPTISYFIYQYEFLDVNYLMT
HHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEE
INYHYMIKLFGTCLGCSYFVALVILFFLLAFLKKVNFKNCLYTILIFTFLIGFFIGLLYF
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
TFIRSITSLLLMLIVFLSDTFAYVGGVLFGKTKLAPKTSPNKTVEGLIFGLVIATIVIML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
IIFGLSYVPIKPKNDMILKSQNVLYNIFGLDFSNSNKTNLTLHKQVLICTTVAFLFLSLI
HHHCCCCCCCCCCCCCEEECCCCEEEEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHH
STIGDLVFSATKRNYDTKDYSNLIPGHGGLLDRIDSHSFVITIMFIFTLVITGSLQDENL
HHHHHHHHHHHHCCCCCCHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCC
FPSIQKVFVEISSSIV
CHHHHHHHHHHHHCCC
>Mature Secondary Structure
MISVNKINEKTKTTFFKRFYSSIFIFLYLLIYFVLALLSDRNYSTPLIDHLYIQQAIAIV
CCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LLVLLPLVWIASYEMNKVIFDNHKITRITLTIIFNICVYAPTISYFIYQYEFLDVNYLMT
HHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEE
INYHYMIKLFGTCLGCSYFVALVILFFLLAFLKKVNFKNCLYTILIFTFLIGFFIGLLYF
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
TFIRSITSLLLMLIVFLSDTFAYVGGVLFGKTKLAPKTSPNKTVEGLIFGLVIATIVIML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
IIFGLSYVPIKPKNDMILKSQNVLYNIFGLDFSNSNKTNLTLHKQVLICTTVAFLFLSLI
HHHCCCCCCCCCCCCCEEECCCCEEEEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHH
STIGDLVFSATKRNYDTKDYSNLIPGHGGLLDRIDSHSFVITIMFIFTLVITGSLQDENL
HHHHHHHHHHHHCCCCCCHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCC
FPSIQKVFVEISSSIV
CHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]