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The map label for this gene is lspA [H]

Identifier: 209554246

GI number: 209554246

Start: 355920

End: 356711

Strand: Reverse

Name: lspA [H]

Synonym: UUR10_0319

Alternate gene names: 209554246

Gene position: 356711-355920 (Counterclockwise)

Preceding gene: 209554209

Following gene: 209554367

Centisome position: 40.79

GC content: 22.47

Gene sequence:

>792_bases
ATGTTTGAAAAAATTACAAATTCAAATTTTTATATCACAATTAAAAAATTTAATGAATCACTTAGAAAAATTAATTTTTT
TAAAAAAATTATTTTAAAAATAGATAATAAAGGCGTTCGTGATTACTTTTTATCGATAACAACATTAGATGTTATTTTTT
ATAAAATAATTAATTTTATTATTATTGCTTTAATTGTGTTATTGTCTGGTTTTTTAGTTCGTGAATGAGCTATTAATCTA
GTTATTAATACTAAAGAAATCTATCATGGTCCTATTTTTCATTTTACATTAAACAATGGGATTGCTCTTGGAAGAATTAA
TAACAATAGTGGAATTGTTTATGCTTTACAATCAATTCCTATTATATTAGGATTTTTATCATTTATTTTTTTAAAAAAAT
CTTATCATTACGCTCCATTACTTTTCTTATTATTTGGCGGTTTAGGAAATATTATTGATCGTTCAATTCCAGAATTAGAA
TTATACAAAGCACTACCAGATATTTTTCATAATAGCTTTATTAATCCTAATAGTGTTGGTGGAGGCAATGACGTTATTAA
TGGTGTTGTTGATTATTGAAAATTTGTCAATAGTATAATTAATCTTTTTGATGTTTATATTGTAGTTGGTGTTTGTGTAT
TAGTTGTTATTTTAATTATTGGTTTTATTATCAAATGAAAAAGTGATAACGACACTAAAGATACTACAAAAAAAGCAGCT
GATGAAAATGATTTAGAAATTAATGAAGTATCTAATAAACCATTTGGATATGATGATTTAGAAAAACCATAA

Upstream 100 bases:

>100_bases
ATGAAGAATGTGTTGCTTTAATGCAAGAGCATGGTCATCTTAAAAAAGATGAATTTGTATCAAAAATGATGAAACAACGT
CCAGAAAAGTATAGCCAATA

Downstream 100 bases:

>100_bases
AAATGAAAATATTATATTCTTTAACATCACCGAAACGGATTGATAAATTTTTAGTAGAAGTTACTGATTATTCGCGAACA
TCAATTAAAAAAATGTTAGA

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MFEKITNSNFYITIKKFNESLRKINFFKKIILKIDNKGVRDYFLSITTLDVIFYKIINFIIIALIVLLSGFLVREWAINL
VINTKEIYHGPIFHFTLNNGIALGRINNNSGIVYALQSIPIILGFLSFIFLKKSYHYAPLLFLLFGGLGNIIDRSIPELE
LYKALPDIFHNSFINPNSVGGGNDVINGVVDYWKFVNSIINLFDVYIVVGVCVLVVILIIGFIIKWKSDNDTKDTTKKAA
DENDLEINEVSNKPFGYDDLEKP

Sequences:

>Translated_263_residues
MFEKITNSNFYITIKKFNESLRKINFFKKIILKIDNKGVRDYFLSITTLDVIFYKIINFIIIALIVLLSGFLVRE*AINL
VINTKEIYHGPIFHFTLNNGIALGRINNNSGIVYALQSIPIILGFLSFIFLKKSYHYAPLLFLLFGGLGNIIDRSIPELE
LYKALPDIFHNSFINPNSVGGGNDVINGVVDY*KFVNSIINLFDVYIVVGVCVLVVILIIGFIIK*KSDNDTKDTTKKAA
DENDLEINEVSNKPFGYDDLEKP
>Mature_263_residues
MFEKITNSNFYITIKKFNESLRKINFFKKIILKIDNKGVRDYFLSITTLDVIFYKIINFIIIALIVLLSGFLVRE*AINL
VINTKEIYHGPIFHFTLNNGIALGRINNNSGIVYALQSIPIILGFLSFIFLKKSYHYAPLLFLLFGGLGNIIDRSIPELE
LYKALPDIFHNSFINPNSVGGGNDVINGVVDY*KFVNSIINLFDVYIVVGVCVLVVILIIGFIIK*KSDNDTKDTTKKAA
DENDLEINEVSNKPFGYDDLEKP

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 29387; Mature: 29387

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEKITNSNFYITIKKFNESLRKINFFKKIILKIDNKGVRDYFLSITTLDVIFYKIINFI
CCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
IIALIVLLSGFLVREAINLVINTKEIYHGPIFHFTLNNGIALGRINNNSGIVYALQSIPI
HHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEEECCCEEEEEEECCCCEEEEHHHHHH
ILGFLSFIFLKKSYHYAPLLFLLFGGLGNIIDRSIPELELYKALPDIFHNSFINPNSVGG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCC
GNDVINGVVDYKFVNSIINLFDVYIVVGVCVLVVILIIGFIIKKSDNDTKDTTKKAADEN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCC
DLEINEVSNKPFGYDDLEKP
CCEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MFEKITNSNFYITIKKFNESLRKINFFKKIILKIDNKGVRDYFLSITTLDVIFYKIINFI
CCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
IIALIVLLSGFLVREAINLVINTKEIYHGPIFHFTLNNGIALGRINNNSGIVYALQSIPI
HHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEEECCCEEEEEEECCCCEEEEHHHHHH
ILGFLSFIFLKKSYHYAPLLFLLFGGLGNIIDRSIPELELYKALPDIFHNSFINPNSVGG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCC
GNDVINGVVDYKFVNSIINLFDVYIVVGVCVLVVILIIGFIIKKSDNDTKDTTKKAADEN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCC
DLEINEVSNKPFGYDDLEKP
CCEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12466555 [H]