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The map label for this gene is asnC [H]

Identifier: 209554140

GI number: 209554140

Start: 416911

End: 418275

Strand: Reverse

Name: asnC [H]

Synonym: UUR10_0374

Alternate gene names: 209554140

Gene position: 418275-416911 (Counterclockwise)

Preceding gene: 209554247

Following gene: 209554536

Centisome position: 47.83

GC content: 29.01

Gene sequence:

>1365_bases
ATGCAATTAAAAATTAAAGAGATTTTTGATCAAGATTATACAAAACTTGAAGGTCAAAAAGTACAAATTAAAGCTTGAGT
TCGTTCAAATCGTGATTCAAAAAAAATTGGTTTTTTAGTTTTAAATGATGGAAGTTCTCTAACAAATTTACAAGCTGTAT
ATCGTGTTGATAAAATTAGTAATTATGAAGAAATAACTGCGGCACGAATGTGAGCAGCAGTTGCTATTGAAGGTGTAATT
AAATTAACTCCAACAGCTAAACAACCATTAGAACTAGAAGTATTAAATGCTCAAATTTTAAAACAAAGTGATGAAGATTT
TTTATTATCAAATAATGATTTAAGTTTAGAAACATTGCGTTTAAATGCCCATTTAAGACCAAGAACAAATTTATTTCATG
CCATTATGAAAGTGCGAGCAACACTTGCTTTTGCAGTTCATGAATTTATGAATCAAAACGAATATAGTTGATTAGCTGCA
CCATTGTTTACAGGAAATGATGCTGAAGGAGCAGGGGAAACTTTTAGTATTCAAAAATTTGATAATGAAGAATTCTTTGG
TAAACAAACTCATTTATCGGTAACAGGGCAATTACAAGCTGAAGCATACGCACAAGCTTTTGGTAATGTATATACATTTG
GCCCTACTTTTAGAGCTGAAAAATCGCACACAAATCGTCATTTAGCTGAATTTTGAATGATTGAACCAGAAATGGCTTTT
GTTGATTTAAAAGGTATGCAAGATATTGTTGAAAATTTAATTAAACATGTTATTAAGGCTGTTTTAGAAAAAAATCAACA
AGAATTAGAATTTTTAGCACAAAGAAACGATGAAAATTTAATTAAAAAACTTCAAAAAGTTGTTGATTCTAAGTTTGAAC
GTATTGAATATAAAGATGCAGTTAAAATTCTAGCTAATGCTGTTAAAAGTGGTCATCAATTCGAAGATAATGAAATCTTT
TTTGGAATGGATTTAGGTTCAGAACATGAAAGATATATGTGCGAAACTTATCATCAAGGACCTGTTTTCTTACAAAATTA
TCCAAAAGATATTAAAGCATTTTATATGAAATTAAATGATGATCAACAAACTGTAGCTTCAACAGATTTACTAATTCCAG
GTGTTGGTGAATTAGTAGGTGGTTCACAACGTGAAGATAATTATGAAAAATTATTGAAACGATGTCAAGAATTAAAAATG
CCAATTGAAAGTTTACAATGATATTTAGATTTACGTCGTTTTGGATATTATATGTCATCAGGTTTTGGAATTGGTTTTGA
ACGTTTAGTGATGTATGTAACAGGAGTTAATAATATTAAAGATACAATTCCATTTCCACGAAGTCATGGCCAAATTGAAT
TTTAA

Upstream 100 bases:

>100_bases
GCAATAAAAACTAATTTAAAGCAAAACTTATTAACTAATGATGTTTTGCTTTTTTATTTATATATTATTTAAAAAAGAAA
AAAAGGTAATGATTTTATAT

Downstream 100 bases:

>100_bases
AAAAAACATCTTAACATCTCCTTTTTTTAGAAACATTCCTAATATCATCACTATCTTTAGAATTTTTTTAGCACTTATTT
GTATTATCTTATTATTGGTT

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MQLKIKEIFDQDYTKLEGQKVQIKAWVRSNRDSKKIGFLVLNDGSSLTNLQAVYRVDKISNYEEITAARMWAAVAIEGVI
KLTPTAKQPLELEVLNAQILKQSDEDFLLSNNDLSLETLRLNAHLRPRTNLFHAIMKVRATLAFAVHEFMNQNEYSWLAA
PLFTGNDAEGAGETFSIQKFDNEEFFGKQTHLSVTGQLQAEAYAQAFGNVYTFGPTFRAEKSHTNRHLAEFWMIEPEMAF
VDLKGMQDIVENLIKHVIKAVLEKNQQELEFLAQRNDENLIKKLQKVVDSKFERIEYKDAVKILANAVKSGHQFEDNEIF
FGMDLGSEHERYMCETYHQGPVFLQNYPKDIKAFYMKLNDDQQTVASTDLLIPGVGELVGGSQREDNYEKLLKRCQELKM
PIESLQWYLDLRRFGYYMSSGFGIGFERLVMYVTGVNNIKDTIPFPRSHGQIEF

Sequences:

>Translated_454_residues
MQLKIKEIFDQDYTKLEGQKVQIKA*VRSNRDSKKIGFLVLNDGSSLTNLQAVYRVDKISNYEEITAARM*AAVAIEGVI
KLTPTAKQPLELEVLNAQILKQSDEDFLLSNNDLSLETLRLNAHLRPRTNLFHAIMKVRATLAFAVHEFMNQNEYS*LAA
PLFTGNDAEGAGETFSIQKFDNEEFFGKQTHLSVTGQLQAEAYAQAFGNVYTFGPTFRAEKSHTNRHLAEF*MIEPEMAF
VDLKGMQDIVENLIKHVIKAVLEKNQQELEFLAQRNDENLIKKLQKVVDSKFERIEYKDAVKILANAVKSGHQFEDNEIF
FGMDLGSEHERYMCETYHQGPVFLQNYPKDIKAFYMKLNDDQQTVASTDLLIPGVGELVGGSQREDNYEKLLKRCQELKM
PIESLQ*YLDLRRFGYYMSSGFGIGFERLVMYVTGVNNIKDTIPFPRSHGQIEF
>Mature_454_residues
MQLKIKEIFDQDYTKLEGQKVQIKA*VRSNRDSKKIGFLVLNDGSSLTNLQAVYRVDKISNYEEITAARM*AAVAIEGVI
KLTPTAKQPLELEVLNAQILKQSDEDFLLSNNDLSLETLRLNAHLRPRTNLFHAIMKVRATLAFAVHEFMNQNEYS*LAA
PLFTGNDAEGAGETFSIQKFDNEEFFGKQTHLSVTGQLQAEAYAQAFGNVYTFGPTFRAEKSHTNRHLAEF*MIEPEMAF
VDLKGMQDIVENLIKHVIKAVLEKNQQELEFLAQRNDENLIKKLQKVVDSKFERIEYKDAVKILANAVKSGHQFEDNEIF
FGMDLGSEHERYMCETYHQGPVFLQNYPKDIKAFYMKLNDDQQTVASTDLLIPGVGELVGGSQREDNYEKLLKRCQELKM
PIESLQ*YLDLRRFGYYMSSGFGIGFERLVMYVTGVNNIKDTIPFPRSHGQIEF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=441, Percent_Identity=39.0022675736961, Blast_Score=282, Evalue=5e-76,
Organism=Homo sapiens, GI4758762, Length=441, Percent_Identity=28.7981859410431, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI45439306, Length=457, Percent_Identity=24.945295404814, Blast_Score=104, Evalue=2e-22,
Organism=Escherichia coli, GI1787161, Length=446, Percent_Identity=43.4977578475336, Blast_Score=374, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI71984122, Length=445, Percent_Identity=29.6629213483146, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17556372, Length=372, Percent_Identity=34.4086021505376, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17551876, Length=481, Percent_Identity=24.5322245322245, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319872, Length=459, Percent_Identity=34.4226579520697, Blast_Score=249, Evalue=6e-67,
Organism=Saccharomyces cerevisiae, GI6321807, Length=458, Percent_Identity=30.7860262008734, Blast_Score=176, Evalue=7e-45,
Organism=Saccharomyces cerevisiae, GI6323011, Length=328, Percent_Identity=25.3048780487805, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI19922416, Length=459, Percent_Identity=31.1546840958606, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI19921528, Length=436, Percent_Identity=30.045871559633, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI17136276, Length=453, Percent_Identity=25.60706401766, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 51228; Mature: 51228

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLKIKEIFDQDYTKLEGQKVQIKAVRSNRDSKKIGFLVLNDGSSLTNLQAVYRVDKISN
CCEEHHHHHCCHHHHCCCCEEEEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCC
YEEITAARMAAVAIEGVIKLTPTAKQPLELEVLNAQILKQSDEDFLLSNNDLSLETLRLN
HHHHHHHHHHHHHHHHHEEECCCCCCCCEEEEHHHHHHHCCCCCEEEECCCCEEEEEEEE
AHLRPRTNLFHAIMKVRATLAFAVHEFMNQNEYSLAAPLFTGNDAEGAGETFSIQKFDNE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECEEECCCCCCCCCEEEEEECCCH
EFFGKQTHLSVTGQLQAEAYAQAFGNVYTFGPTFRAEKSHTNRHLAEFMIEPEMAFVDLK
HHCCCCEEEEEEECHHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEHH
GMQDIVENLIKHVIKAVLEKNQQELEFLAQRNDENLIKKLQKVVDSKFERIEYKDAVKIL
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANAVKSGHQFEDNEIFFGMDLGSEHERYMCETYHQGPVFLQNYPKDIKAFYMKLNDDQQT
HHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHCCCCCEEECCCCHHHHHHHEEECCCHHH
VASTDLLIPGVGELVGGSQREDNYEKLLKRCQELKMPIESLQYLDLRRFGYYMSSGFGIG
HHHCCEECCCCHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCC
FERLVMYVTGVNNIKDTIPFPRSHGQIEF
HHHHHHHHHCCCCHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MQLKIKEIFDQDYTKLEGQKVQIKAVRSNRDSKKIGFLVLNDGSSLTNLQAVYRVDKISN
CCEEHHHHHCCHHHHCCCCEEEEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCC
YEEITAARMAAVAIEGVIKLTPTAKQPLELEVLNAQILKQSDEDFLLSNNDLSLETLRLN
HHHHHHHHHHHHHHHHHEEECCCCCCCCEEEEHHHHHHHCCCCCEEEECCCCEEEEEEEE
AHLRPRTNLFHAIMKVRATLAFAVHEFMNQNEYSLAAPLFTGNDAEGAGETFSIQKFDNE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECEEECCCCCCCCCEEEEEECCCH
EFFGKQTHLSVTGQLQAEAYAQAFGNVYTFGPTFRAEKSHTNRHLAEFMIEPEMAFVDLK
HHCCCCEEEEEEECHHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEHH
GMQDIVENLIKHVIKAVLEKNQQELEFLAQRNDENLIKKLQKVVDSKFERIEYKDAVKIL
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANAVKSGHQFEDNEIFFGMDLGSEHERYMCETYHQGPVFLQNYPKDIKAFYMKLNDDQQT
HHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHCCCCCEEECCCCHHHHHHHEEECCCHHH
VASTDLLIPGVGELVGGSQREDNYEKLLKRCQELKMPIESLQYLDLRRFGYYMSSGFGIG
HHHCCEECCCCHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCC
FERLVMYVTGVNNIKDTIPFPRSHGQIEF
HHHHHHHHHCCCCHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA