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The map label for this gene is engA [H]

Identifier: 209554037

GI number: 209554037

Start: 472969

End: 474297

Strand: Reverse

Name: engA [H]

Synonym: UUR10_0426

Alternate gene names: 209554037

Gene position: 474297-472969 (Counterclockwise)

Preceding gene: 209554166

Following gene: 209554471

Centisome position: 54.24

GC content: 29.35

Gene sequence:

>1329_bases
ATGAGAACTATTGCTATTGTTGGAAAGCCAAATGTTGGTAAATCATCACTATTTAATCGTATTTTAATGCGACGAAAATC
GATTGTGGATGATCAACCTGGAGTAACAAGAGATCGAATTTATGATGTTGGAAATTGACTAACAAGAGACTTTATGTTAA
TTGACACTGGTGGAATAATTAGTTCTGAAGATACTTATCAAGATAACATTAACGAACAAGTTTTATTTGCCATTAATGAA
GCAAATACAATTATTTTTTTAGTTTCAGCAAAAGATGGCATTAATAATGATGATAAAAAAATCGCTAAAATGTTAAAAGA
AAAAGCAAAAGATAAAAAAGTTATTTTGGTCGTAAATAAGGTTGAATCTGAAAAATATTATTTTAATGAGGGCGAATTAT
ATTCATTTGGATTTGGTAAATTTTTTAAAATTTCAGCTGAACATGGAATTGGAATGGGTGATCTTTTAGATGAATTAGTA
AAAGATATGCCAATTCAAAATGCTTTAGACCAACAAGAACGTTTTAAATTTTGCATTATTGGAAGGCCTAATGTTGGTAA
AAGTTCATTAACTAATACTATTTTAGGTGAACAAAGAATGATTGTTAACGCTGAAGCTGGTTCAACACGTGATTCAATTG
ATAATGACTTTAGTTATCATAATAAAAAATATACAATCATTGATACAGCAGGAGTACGACGAAAAGGCAAAATTGTTGAA
GCAGTAGAAAAATATGCTGTTTTACGAACACAAAAAGCGATTGAAAGATCACAATTAATTTTATTAGTACTTGATGGATC
AGAGCCATTTAAAGAACAAGATGAAGTTGTAGGTGGTTTAGCATATGATGCTAATATTCCTACCATTATTGTTGTGAATA
AGTGAGATAATATCGTTAATAAAAATAGTCATACAATGGAAATGGTCAAAAAACAAATTCGTTCACAATTTAAATACTTA
TCATGAGCACCAATTGTTTTTATTAGTGCTTTAGATAATAAAAGAATTCACACTATTTTTGAAACTATTGAACTTGTGCG
TGAGCAAGCAATGCGCAAGGTTGCTACTTCTTTATTAAATGATGTAGTTATTAAAGCGAACGCCTTTCAAGAACCGCCTC
CTTTTAAAGGTGGAAGAATTAGTATTTCATACGTTGTTCAAGTCCAATCACAAATTCCTACTTTTGTTTTAAAATGTAAT
AATCCAAAATTTTTACATTTTAGTTATGCTCGTTACATTGAAAATGAAATTCGTAAAGCGTTTGGATTTGATAGTGTACC
AATAACATTGTATTGACAAGATAAAAACAAAAAATTACGAGGGGAGTAA

Upstream 100 bases:

>100_bases
GTTTATATTAAAAATATAAATATAAATTGCTTAATCAAGCATTATTAAATGGTTTTTATTATAATTACATATAATGTTTG
TAACTAAAAAGGAAGAATTT

Downstream 100 bases:

>100_bases
TTATTAATTATGAGTAAAATTTTAATTATTGGAAGTGGTGCTTTTGGAAGTGCTTTAACACAAGTTTTAGTTTCAAACCA
TCACGCAGTTGATGTTTATG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MRTIAIVGKPNVGKSSLFNRILMRRKSIVDDQPGVTRDRIYDVGNWLTRDFMLIDTGGIISSEDTYQDNINEQVLFAINE
ANTIIFLVSAKDGINNDDKKIAKMLKEKAKDKKVILVVNKVESEKYYFNEGELYSFGFGKFFKISAEHGIGMGDLLDELV
KDMPIQNALDQQERFKFCIIGRPNVGKSSLTNTILGEQRMIVNAEAGSTRDSIDNDFSYHNKKYTIIDTAGVRRKGKIVE
AVEKYAVLRTQKAIERSQLILLVLDGSEPFKEQDEVVGGLAYDANIPTIIVVNKWDNIVNKNSHTMEMVKKQIRSQFKYL
SWAPIVFISALDNKRIHTIFETIELVREQAMRKVATSLLNDVVIKANAFQEPPPFKGGRISISYVVQVQSQIPTFVLKCN
NPKFLHFSYARYIENEIRKAFGFDSVPITLYWQDKNKKLRGE

Sequences:

>Translated_442_residues
MRTIAIVGKPNVGKSSLFNRILMRRKSIVDDQPGVTRDRIYDVGN*LTRDFMLIDTGGIISSEDTYQDNINEQVLFAINE
ANTIIFLVSAKDGINNDDKKIAKMLKEKAKDKKVILVVNKVESEKYYFNEGELYSFGFGKFFKISAEHGIGMGDLLDELV
KDMPIQNALDQQERFKFCIIGRPNVGKSSLTNTILGEQRMIVNAEAGSTRDSIDNDFSYHNKKYTIIDTAGVRRKGKIVE
AVEKYAVLRTQKAIERSQLILLVLDGSEPFKEQDEVVGGLAYDANIPTIIVVNK*DNIVNKNSHTMEMVKKQIRSQFKYL
S*APIVFISALDNKRIHTIFETIELVREQAMRKVATSLLNDVVIKANAFQEPPPFKGGRISISYVVQVQSQIPTFVLKCN
NPKFLHFSYARYIENEIRKAFGFDSVPITLY*QDKNKKLRGE
>Mature_442_residues
MRTIAIVGKPNVGKSSLFNRILMRRKSIVDDQPGVTRDRIYDVGN*LTRDFMLIDTGGIISSEDTYQDNINEQVLFAINE
ANTIIFLVSAKDGINNDDKKIAKMLKEKAKDKKVILVVNKVESEKYYFNEGELYSFGFGKFFKISAEHGIGMGDLLDELV
KDMPIQNALDQQERFKFCIIGRPNVGKSSLTNTILGEQRMIVNAEAGSTRDSIDNDFSYHNKKYTIIDTAGVRRKGKIVE
AVEKYAVLRTQKAIERSQLILLVLDGSEPFKEQDEVVGGLAYDANIPTIIVVNK*DNIVNKNSHTMEMVKKQIRSQFKYL
S*APIVFISALDNKRIHTIFETIELVREQAMRKVATSLLNDVVIKANAFQEPPPFKGGRISISYVVQVQSQIPTFVLKCN
NPKFLHFSYARYIENEIRKAFGFDSVPITLY*QDKNKKLRGE

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=455, Percent_Identity=35.3846153846154, Blast_Score=270, Evalue=1e-73,
Organism=Escherichia coli, GI2367268, Length=135, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323665, Length=191, Percent_Identity=31.9371727748691, Blast_Score=78, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49585; Mature: 49585

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTIAIVGKPNVGKSSLFNRILMRRKSIVDDQPGVTRDRIYDVGNLTRDFMLIDTGGIIS
CCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHEECCCCCCEEEEEEECCCEEC
SEDTYQDNINEQVLFAINEANTIIFLVSAKDGINNDDKKIAKMLKEKAKDKKVILVVNKV
CCCCHHCCCCCEEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEE
ESEKYYFNEGELYSFGFGKFFKISAEHGIGMGDLLDELVKDMPIQNALDQQERFKFCIIG
CCCEEEECCCCEEEECCCEEEEEECCCCCCHHHHHHHHHHCCCCHHHCCHHHCCEEEEEE
RPNVGKSSLTNTILGEQRMIVNAEAGSTRDSIDNDFSYHNKKYTIIDTAGVRRKGKIVEA
CCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHH
VEKYAVLRTQKAIERSQLILLVLDGSEPFKEQDEVVGGLAYDANIPTIIVVNKDNIVNKN
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHEEEEECCCCCEEEEECCCCCCCCC
SHTMEMVKKQIRSQFKYLSAPIVFISALDNKRIHTIFETIELVREQAMRKVATSLLNDVV
CHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
IKANAFQEPPPFKGGRISISYVVQVQSQIPTFVLKCNNPKFLHFSYARYIENEIRKAFGF
EEECCCCCCCCCCCCEEEEEEEEEECCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHCC
DSVPITLYQDKNKKLRGE
CCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MRTIAIVGKPNVGKSSLFNRILMRRKSIVDDQPGVTRDRIYDVGNLTRDFMLIDTGGIIS
CCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHEECCCCCCEEEEEEECCCEEC
SEDTYQDNINEQVLFAINEANTIIFLVSAKDGINNDDKKIAKMLKEKAKDKKVILVVNKV
CCCCHHCCCCCEEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEE
ESEKYYFNEGELYSFGFGKFFKISAEHGIGMGDLLDELVKDMPIQNALDQQERFKFCIIG
CCCEEEECCCCEEEECCCEEEEEECCCCCCHHHHHHHHHHCCCCHHHCCHHHCCEEEEEE
RPNVGKSSLTNTILGEQRMIVNAEAGSTRDSIDNDFSYHNKKYTIIDTAGVRRKGKIVEA
CCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHH
VEKYAVLRTQKAIERSQLILLVLDGSEPFKEQDEVVGGLAYDANIPTIIVVNKDNIVNKN
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHEEEEECCCCCEEEEECCCCCCCCC
SHTMEMVKKQIRSQFKYLSAPIVFISALDNKRIHTIFETIELVREQAMRKVATSLLNDVV
CHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
IKANAFQEPPPFKGGRISISYVVQVQSQIPTFVLKCNNPKFLHFSYARYIENEIRKAFGF
EEECCCCCCCCCCCCEEEEEEEEEECCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHCC
DSVPITLYQDKNKKLRGE
CCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA