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The map label for this gene is rhtB [C]

Identifier: 209551908

GI number: 209551908

Start: 4507241

End: 4507858

Strand: Reverse

Name: rhtB [C]

Synonym: Rleg2_4341

Alternate gene names: 209551908

Gene position: 4507858-4507241 (Counterclockwise)

Preceding gene: 209551910

Following gene: 209551907

Centisome position: 99.34

GC content: 62.78

Gene sequence:

>618_bases
ATGAGCCTTACCGCCCTGATCGCCTATGCCGGAGCGCTGTTCATCGCCGCTGCCATTCCCGGACCGGGGATTACCGCGAT
CGTCGCCCGCGCGCTCGGCTCGAATTTCCGCGAGACCTTCTTCATGGGTCTCGGACTGGTGCTCGGCGACATGACCTATC
TCACCGCGGTCATTCTCGGCCTCGCCTTCGTGGCGCAGACCTTCACCGAGGTGTTCATCGCGATCAAAATCGCCGGCGCC
CTCTATCTCGGCTATATCGCCTGGAAACTCTGGACGGCGGGACTGCTGCCGCAAGATATCGCGGCGAAGAAATCCAGCAA
TATCGGCCTGTCCTTCCTCTCCGGCCTGCTGGTGACGCTCGGCAATCCGAAAACCATGCTGTTTTATGTCGCGCTGGCGC
CGACGCTGATCGATATCGGCAATATCAGCCTCCGCGACTACGCGATGCTGCTCGCCGTCACCTTCGTGGTGCTGATCGTG
GTGCTGGTGCCCTATATGCTGCTGGCTTCGCGAGCCCGGACGATGCTGAAAAAGCCGCATGCCTTGAAGGCGCTGAACCG
GGTTGCGGCCGGCATCCTCGCCGGCACGGCGGCCTTCATCGCCACGCGGGCGGCCTGA

Upstream 100 bases:

>100_bases
AGACCTATTCCTTATGATGATGGACCGATCAGCGCCGAAGCATTGATGAAGCCGCGACGCGCGCCTATGGAGAGGCTGCC
CAATCTCGTGGATATCAAAG

Downstream 100 bases:

>100_bases
AATAAACATCCGGCAAGAAACGGTTTTCAAAGCTTTTTTTCTCCGCGTCCCGCTCTCCCTATACGAACGCGGTCTGGTCT
CTTCAGCCCTTTGACCCTAT

Product: lysine exporter protein LysE/YggA

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MSLTALIAYAGALFIAAAIPGPGITAIVARALGSNFRETFFMGLGLVLGDMTYLTAVILGLAFVAQTFTEVFIAIKIAGA
LYLGYIAWKLWTAGLLPQDIAAKKSSNIGLSFLSGLLVTLGNPKTMLFYVALAPTLIDIGNISLRDYAMLLAVTFVVLIV
VLVPYMLLASRARTMLKKPHALKALNRVAAGILAGTAAFIATRAA

Sequences:

>Translated_205_residues
MSLTALIAYAGALFIAAAIPGPGITAIVARALGSNFRETFFMGLGLVLGDMTYLTAVILGLAFVAQTFTEVFIAIKIAGA
LYLGYIAWKLWTAGLLPQDIAAKKSSNIGLSFLSGLLVTLGNPKTMLFYVALAPTLIDIGNISLRDYAMLLAVTFVVLIV
VLVPYMLLASRARTMLKKPHALKALNRVAAGILAGTAAFIATRAA
>Mature_204_residues
SLTALIAYAGALFIAAAIPGPGITAIVARALGSNFRETFFMGLGLVLGDMTYLTAVILGLAFVAQTFTEVFIAIKIAGAL
YLGYIAWKLWTAGLLPQDIAAKKSSNIGLSFLSGLLVTLGNPKTMLFYVALAPTLIDIGNISLRDYAMLLAVTFVVLIVV
LVPYMLLASRARTMLKKPHALKALNRVAAGILAGTAAFIATRAA

Specific function: Conducts The Efflux Of Homoserine And Homoserine Lactone. [C]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994979, Length=189, Percent_Identity=30.6878306878307, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 21565; Mature: 21434

Theoretical pI: Translated: 10.54; Mature: 10.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTALIAYAGALFIAAAIPGPGITAIVARALGSNFRETFFMGLGLVLGDMTYLTAVILG
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LAFVAQTFTEVFIAIKIAGALYLGYIAWKLWTAGLLPQDIAAKKSSNIGLSFLSGLLVTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHC
GNPKTMLFYVALAPTLIDIGNISLRDYAMLLAVTFVVLIVVLVPYMLLASRARTMLKKPH
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
ALKALNRVAAGILAGTAAFIATRAA
HHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLTALIAYAGALFIAAAIPGPGITAIVARALGSNFRETFFMGLGLVLGDMTYLTAVILG
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LAFVAQTFTEVFIAIKIAGALYLGYIAWKLWTAGLLPQDIAAKKSSNIGLSFLSGLLVTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHC
GNPKTMLFYVALAPTLIDIGNISLRDYAMLLAVTFVVLIVVLVPYMLLASRARTMLKKPH
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
ALKALNRVAAGILAGTAAFIATRAA
HHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]