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The map label for this gene is pyrF [H]

Identifier: 209551892

GI number: 209551892

Start: 4491070

End: 4491777

Strand: Reverse

Name: pyrF [H]

Synonym: Rleg2_4325

Alternate gene names: 209551892

Gene position: 4491777-4491070 (Counterclockwise)

Preceding gene: 209551893

Following gene: 209551891

Centisome position: 98.98

GC content: 65.68

Gene sequence:

>708_bases
ATGGACGCACGCGAGCGGCTGATCGTCGGCCTGGATGTTCCAACGATCGGCGAGGCGGAAAAACTGGTTTCCACGCTCGG
CGACGACATTCTCTTCTATAAGATCGGTTATCAACTGGTCTTTGCCGGCGGCCTGGAATTCGCCCGTGATCTCGCCGCAA
GCGGCAAGAAGATCTTTCTCGACATGAAGCTGCTCGACATCGACAACACCGTTGCCTCGGGTGTCGAGAACATCGCCAAG
ATGGGCATGTCGATGCTGACGCTGCATGCCTATCCCAAGGCGATGAAGGCGGCGGTCGAGGCGGCGGCCGGCTCCGGCCT
CTGCCTGCTCGGCGTCACCGTGCTGACCTCCATGGATGCCGAAGACCTTGCAGACGCCGGCTACAGCCAGGATCCGCACA
GCCTGGTGCTGCGCCGCGCCGGACAGGCGCGCGCCGCCGGCATGGGCGGCATCGTCTGCTCGGCAGCCGAGGCGGCCGAA
GTGCGCGAGATCGTCGGACCCGACATGGCGATCGTCACCCCCGGCATTCGACCGACGGGCAGCGACCATGGCGACCAGAA
GCGGGTGATGACGCCGTTCGACGCGCTGAAGGCGGGGGCGACGCATCTTGTCGTTGCCCGGCCGATCGTCAAGGCGCCCG
ATCCGAGAGATGCCGCCCGCGCGGTGCTCAACGAAATGGTCGGCGCCCTCTGGCCGGCAAACCGCTGA

Upstream 100 bases:

>100_bases
CCAGCCGGCCGGCGGCGGCAATCTCTATGCTTTCGGCCTTGCGGATCAGGCCCTGACATGCGACTGGACACCCATCGAAG
ACTGGCGGGGGTGACTTGAA

Downstream 100 bases:

>100_bases
CAGAAACCAAGACAAAAGGGAGAAGATCATGGCCAAGGGATACTGGATCGCCCGCGTCGACGTTCGCGATGCCGAGCGCT
ACAAGGATTACGTGGCGGCG

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MDARERLIVGLDVPTIGEAEKLVSTLGDDILFYKIGYQLVFAGGLEFARDLAASGKKIFLDMKLLDIDNTVASGVENIAK
MGMSMLTLHAYPKAMKAAVEAAAGSGLCLLGVTVLTSMDAEDLADAGYSQDPHSLVLRRAGQARAAGMGGIVCSAAEAAE
VREIVGPDMAIVTPGIRPTGSDHGDQKRVMTPFDALKAGATHLVVARPIVKAPDPRDAARAVLNEMVGALWPANR

Sequences:

>Translated_235_residues
MDARERLIVGLDVPTIGEAEKLVSTLGDDILFYKIGYQLVFAGGLEFARDLAASGKKIFLDMKLLDIDNTVASGVENIAK
MGMSMLTLHAYPKAMKAAVEAAAGSGLCLLGVTVLTSMDAEDLADAGYSQDPHSLVLRRAGQARAAGMGGIVCSAAEAAE
VREIVGPDMAIVTPGIRPTGSDHGDQKRVMTPFDALKAGATHLVVARPIVKAPDPRDAARAVLNEMVGALWPANR
>Mature_235_residues
MDARERLIVGLDVPTIGEAEKLVSTLGDDILFYKIGYQLVFAGGLEFARDLAASGKKIFLDMKLLDIDNTVASGVENIAK
MGMSMLTLHAYPKAMKAAVEAAAGSGLCLLGVTVLTSMDAEDLADAGYSQDPHSLVLRRAGQARAAGMGGIVCSAAEAAE
VREIVGPDMAIVTPGIRPTGSDHGDQKRVMTPFDALKAGATHLVVARPIVKAPDPRDAARAVLNEMVGALWPANR

Specific function: Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) [H]

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787537, Length=221, Percent_Identity=38.4615384615385, Blast_Score=144, Evalue=5e-36,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR014732
- InterPro:   IPR018089
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.23 [H]

Molecular weight: Translated: 24641; Mature: 24641

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00156 OMPDECASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDARERLIVGLDVPTIGEAEKLVSTLGDDILFYKIGYQLVFAGGLEFARDLAASGKKIFL
CCCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEHHHHHEECCCHHHHHHHHCCCCEEEE
DMKLLDIDNTVASGVENIAKMGMSMLTLHAYPKAMKAAVEAAAGSGLCLLGVTVLTSMDA
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCH
EDLADAGYSQDPHSLVLRRAGQARAAGMGGIVCSAAEAAEVREIVGPDMAIVTPGIRPTG
HHHHHCCCCCCHHHHHHHHCCCHHHCCCCCHHCCHHHHHHHHHHHCCCEEEEECCCCCCC
SDHGDQKRVMTPFDALKAGATHLVVARPIVKAPDPRDAARAVLNEMVGALWPANR
CCCCCCCCCCCHHHHHHCCCCEEEEECCHHCCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDARERLIVGLDVPTIGEAEKLVSTLGDDILFYKIGYQLVFAGGLEFARDLAASGKKIFL
CCCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEHHHHHEECCCHHHHHHHHCCCCEEEE
DMKLLDIDNTVASGVENIAKMGMSMLTLHAYPKAMKAAVEAAAGSGLCLLGVTVLTSMDA
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCH
EDLADAGYSQDPHSLVLRRAGQARAAGMGGIVCSAAEAAEVREIVGPDMAIVTPGIRPTG
HHHHHCCCCCCHHHHHHHHCCCHHHCCCCCHHCCHHHHHHHHHHHCCCEEEEECCCCCCC
SDHGDQKRVMTPFDALKAGATHLVVARPIVKAPDPRDAARAVLNEMVGALWPANR
CCCCCCCCCCCHHHHHHCCCCEEEEECCHHCCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA