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The map label for this gene is yajO [H]

Identifier: 209551846

GI number: 209551846

Start: 4448935

End: 4449882

Strand: Reverse

Name: yajO [H]

Synonym: Rleg2_4278

Alternate gene names: 209551846

Gene position: 4449882-4448935 (Counterclockwise)

Preceding gene: 209551848

Following gene: 209551845

Centisome position: 98.06

GC content: 61.18

Gene sequence:

>948_bases
ATGGAAATGCGCCGGCTTGGAAAAACAGGTCTTTCGGTCGCGCCGATCGTCATCGGCGGCAATGTCTTCGGCTGGACGGC
CCACGAGAAAACATCCTTCGCCATTCTCGACGCCTTCTTCGATGCGGGCCTCAACACAATCGATACGGCGGATGTCTATT
CCGCCTGGGTTCCCGGCAACAAGGGCGGCGATTCCGAGGAGATCATTGGGCGCTGGCTGAAGCAGGCCAAGGTTTCCCGC
GACAAGGCCGTGATCGTCACCAAGGTCGGCTCGGACATGGGACAGGGAAAAACGCTCAAGGAGCGCTATATCCTGAAGGC
GGTCGAGGATTCGCTCAGCCGGCTGCAAACCGATTATATCGATCTCTATCTCTCGCATTGGCCGGACGCCGATACGCCCC
ACGAGGAAACGCTCGGCGCCTTTGCCAAGCTGAAGCAGCAGGGCAAGATCCGCGCCATCGGCTGCTCGAATTATGATGCG
GCGCTGCTGGAGGCGTCCTTCGACGCTGCCGAAAAGGCCGGCCTGCCGCGCTACGATGTGGTGCAGCCGGAATATAACCT
CTATGAGCGCTCGAGCTTCGAGGGGCCGCTGGCCGATCTCTGCGTCAAAGAGGATATCGGCGTCATCACCTATTTCAGCC
TCGCCGCCGGCTTCCTCACCGGCAAGTACCGCAGCAAGGCGGATACGCAAGGCCGTGCCCGCGAGGGCCGGGTTTCGACC
TATTTCGACGACAAGGGCCTGCGCATTCTTGCTGCCCTCGACAGGGTGTCCAACGAAACCGGTGCCAAGCCCGCGGAAAT
TTCGCTCGCCTGGCTTTTGCGCAAGAAGGGCGTGACGGCGCCGATCGCCAGCGCCACCAGTCTTTCGCAGCTTGAAAGCC
TGGCGAAATCAGCGACACTTCAGCTTTCCGATGACGCGATGGCGCTGCTCGACGAAGCCGGCCGCTGA

Upstream 100 bases:

>100_bases
TTCTCTCAGATCGTCAGAGAATGATGTTTCGGCATCATGCTCCGGGACGGCGTTCTGCCGTATCCGCGATTTCAATTACA
TCACCATATTGGAGAGCGTC

Downstream 100 bases:

>100_bases
AAGAGAAGAGACGATGACCGTGACGATCCGCGATGCCCGCCCGGAAGACGAAACCCGCTGGCGCGAGCTCTGGGCTGATT
ATCTCGCCTTCTACGAGGTC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MEMRRLGKTGLSVAPIVIGGNVFGWTAHEKTSFAILDAFFDAGLNTIDTADVYSAWVPGNKGGDSEEIIGRWLKQAKVSR
DKAVIVTKVGSDMGQGKTLKERYILKAVEDSLSRLQTDYIDLYLSHWPDADTPHEETLGAFAKLKQQGKIRAIGCSNYDA
ALLEASFDAAEKAGLPRYDVVQPEYNLYERSSFEGPLADLCVKEDIGVITYFSLAAGFLTGKYRSKADTQGRAREGRVST
YFDDKGLRILAALDRVSNETGAKPAEISLAWLLRKKGVTAPIASATSLSQLESLAKSATLQLSDDAMALLDEAGR

Sequences:

>Translated_315_residues
MEMRRLGKTGLSVAPIVIGGNVFGWTAHEKTSFAILDAFFDAGLNTIDTADVYSAWVPGNKGGDSEEIIGRWLKQAKVSR
DKAVIVTKVGSDMGQGKTLKERYILKAVEDSLSRLQTDYIDLYLSHWPDADTPHEETLGAFAKLKQQGKIRAIGCSNYDA
ALLEASFDAAEKAGLPRYDVVQPEYNLYERSSFEGPLADLCVKEDIGVITYFSLAAGFLTGKYRSKADTQGRAREGRVST
YFDDKGLRILAALDRVSNETGAKPAEISLAWLLRKKGVTAPIASATSLSQLESLAKSATLQLSDDAMALLDEAGR
>Mature_315_residues
MEMRRLGKTGLSVAPIVIGGNVFGWTAHEKTSFAILDAFFDAGLNTIDTADVYSAWVPGNKGGDSEEIIGRWLKQAKVSR
DKAVIVTKVGSDMGQGKTLKERYILKAVEDSLSRLQTDYIDLYLSHWPDADTPHEETLGAFAKLKQQGKIRAIGCSNYDA
ALLEASFDAAEKAGLPRYDVVQPEYNLYERSSFEGPLADLCVKEDIGVITYFSLAAGFLTGKYRSKADTQGRAREGRVST
YFDDKGLRILAALDRVSNETGAKPAEISLAWLLRKKGVTAPIASATSLSQLESLAKSATLQLSDDAMALLDEAGR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=301, Percent_Identity=28.9036544850498, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI27436964, Length=301, Percent_Identity=28.2392026578073, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI4504825, Length=298, Percent_Identity=28.8590604026846, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI27436966, Length=301, Percent_Identity=28.2392026578073, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI27436962, Length=301, Percent_Identity=28.2392026578073, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI27436971, Length=301, Percent_Identity=29.2358803986711, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI41152114, Length=227, Percent_Identity=33.920704845815, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI223718702, Length=227, Percent_Identity=33.0396475770925, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI41327764, Length=205, Percent_Identity=34.1463414634146, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI223718708, Length=181, Percent_Identity=33.1491712707182, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI87081735, Length=324, Percent_Identity=33.641975308642, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1789199, Length=338, Percent_Identity=32.8402366863905, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1789375, Length=326, Percent_Identity=30.6748466257669, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1788070, Length=334, Percent_Identity=29.6407185628743, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788081, Length=289, Percent_Identity=30.4498269896194, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1786400, Length=277, Percent_Identity=26.3537906137184, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI48994888, Length=144, Percent_Identity=32.6388888888889, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87082198, Length=264, Percent_Identity=26.8939393939394, Blast_Score=71, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6325169, Length=338, Percent_Identity=28.698224852071, Blast_Score=115, Evalue=9e-27,
Organism=Saccharomyces cerevisiae, GI6323998, Length=338, Percent_Identity=27.810650887574, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6319958, Length=307, Percent_Identity=27.3615635179153, Blast_Score=102, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6319951, Length=338, Percent_Identity=26.6272189349112, Blast_Score=93, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6321052, Length=171, Percent_Identity=34.5029239766082, Blast_Score=83, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6322615, Length=253, Percent_Identity=26.4822134387352, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24640980, Length=345, Percent_Identity=26.6666666666667, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI45549126, Length=345, Percent_Identity=26.6666666666667, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24644950, Length=309, Percent_Identity=27.5080906148867, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24646155, Length=324, Percent_Identity=28.0864197530864, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24646159, Length=195, Percent_Identity=32.3076923076923, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34255; Mature: 34255

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMRRLGKTGLSVAPIVIGGNVFGWTAHEKTSFAILDAFFDAGLNTIDTADVYSAWVPGN
CCCHHHCCCCCEEEEEEECCCEEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHEECCCC
KGGDSEEIIGRWLKQAKVSRDKAVIVTKVGSDMGQGKTLKERYILKAVEDSLSRLQTDYI
CCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DLYLSHWPDADTPHEETLGAFAKLKQQGKIRAIGCSNYDAALLEASFDAAEKAGLPRYDV
HHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCC
VQPEYNLYERSSFEGPLADLCVKEDIGVITYFSLAAGFLTGKYRSKADTQGRAREGRVST
CCCCCCHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEE
YFDDKGLRILAALDRVSNETGAKPAEISLAWLLRKKGVTAPIASATSLSQLESLAKSATL
EECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCEE
QLSDDAMALLDEAGR
EECCHHHHHHHHCCC
>Mature Secondary Structure
MEMRRLGKTGLSVAPIVIGGNVFGWTAHEKTSFAILDAFFDAGLNTIDTADVYSAWVPGN
CCCHHHCCCCCEEEEEEECCCEEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHEECCCC
KGGDSEEIIGRWLKQAKVSRDKAVIVTKVGSDMGQGKTLKERYILKAVEDSLSRLQTDYI
CCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DLYLSHWPDADTPHEETLGAFAKLKQQGKIRAIGCSNYDAALLEASFDAAEKAGLPRYDV
HHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCC
VQPEYNLYERSSFEGPLADLCVKEDIGVITYFSLAAGFLTGKYRSKADTQGRAREGRVST
CCCCCCHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEE
YFDDKGLRILAALDRVSNETGAKPAEISLAWLLRKKGVTAPIASATSLSQLESLAKSATL
EECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCEE
QLSDDAMALLDEAGR
EECCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]