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The map label for this gene is yccK [H]

Identifier: 209551841

GI number: 209551841

Start: 4445081

End: 4446073

Strand: Reverse

Name: yccK [H]

Synonym: Rleg2_4273

Alternate gene names: 209551841

Gene position: 4446073-4445081 (Counterclockwise)

Preceding gene: 209551843

Following gene: 209551840

Centisome position: 97.98

GC content: 65.46

Gene sequence:

>993_bases
ATGAAAACCCGGAAACTCGGAAACGATCTGGCCGTCTCTGCCGTCGGCCTCGGCTGCATGGGCATGAGTTTCGCCTATGG
CGCCAGCGACGATGCGGAATCGGTGAGGACGCTCCATCGCGCCGTCGAACTCGGCGTCACGTTTTTCGACACTGCCGAAG
TCTATGGCCCCTTTACCAACGAAGCCCTTGTCGGAAAGGTGCTGAAACCATTCCGCGACCGCGTGGTGATCGCCACCAAG
TTCGGCTTCAAGATCGATACCAGCCAGCAAGGTGCCGCCGCCATCGCCGGCGTCGACGGCCGCCCCGAGCATGTGCGGGC
GGTCGCCGAGGCCTCATTGAAACGGCTCGGCATCGAAACCATCGACCTCTTCTACCAGCACCGCGTCGATCCCAACGTGC
CGATCGAGGAGACGGTCGGCGTCATGGGCGAGCTGGTGAGGGAAGGCAAGGTCCGCGCCCTCGGCCTCTCCGAAGCCGGC
AGCGCCACCATCCGCCGCGCCCATGCGGTCCATCCGATCGCAGCGCTGCAGAGCGAATATTCGCTCTGGACGCGCGATCC
GGAGGAAGACGTGCTTGCCACCTGCCGCGAACTCGGCATCGGCTTCGTGCCCTACAGCCCGCTCGGCCGGGGTTTTCTGA
CAGGGGCGATCAAGACCGAAGATCTTGCCGCGGATGATTTCCGCCGGCAGGTGCCGCGCTTCCAGGCGGAGAATTTCGAC
GCCAACGCCGCCCTCGTCGCGACGCTCGAACAGCTGGCTGCCGAGAAGGGCGTGACCGCCGCACAGCTGGCGCTCGCCTG
GGTGCTGGGCCAGGGAGACGACATCGTGCCGATCCCCGGCGCCCGCAAGCTTCACCATCTCGAACAGAACGCCGCTGCCG
CCGATATCGTGCTCAGCGCGGCCGAACTCGATCAGCTCGGCGCGGCGATCCCGGCCGCACAGGTGGCGGGAAAGCGCTAT
TCGGACGCCTCGCTTGCGATGACGAACCTTTAA

Upstream 100 bases:

>100_bases
CAACCCGTTAGAAACCACATGTATTTTCTGACTGGTGCGGCAAGGATATGGTCTGCCCGTACCGCATAGAGCGGTCGCCA
GCTCAGAAAAGGAGCGCAAC

Downstream 100 bases:

>100_bases
GCGACAAAAGCCCGGCATAGAGCCTTTCCTGGTTAGATTGAAGCATTCTGTTGGCTCAAACGGAGTCGGATGGTCGACCG
GCCGGCGCGCGTCGTAGCCC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MKTRKLGNDLAVSAVGLGCMGMSFAYGASDDAESVRTLHRAVELGVTFFDTAEVYGPFTNEALVGKVLKPFRDRVVIATK
FGFKIDTSQQGAAAIAGVDGRPEHVRAVAEASLKRLGIETIDLFYQHRVDPNVPIEETVGVMGELVREGKVRALGLSEAG
SATIRRAHAVHPIAALQSEYSLWTRDPEEDVLATCRELGIGFVPYSPLGRGFLTGAIKTEDLAADDFRRQVPRFQAENFD
ANAALVATLEQLAAEKGVTAAQLALAWVLGQGDDIVPIPGARKLHHLEQNAAAADIVLSAAELDQLGAAIPAAQVAGKRY
SDASLAMTNL

Sequences:

>Translated_330_residues
MKTRKLGNDLAVSAVGLGCMGMSFAYGASDDAESVRTLHRAVELGVTFFDTAEVYGPFTNEALVGKVLKPFRDRVVIATK
FGFKIDTSQQGAAAIAGVDGRPEHVRAVAEASLKRLGIETIDLFYQHRVDPNVPIEETVGVMGELVREGKVRALGLSEAG
SATIRRAHAVHPIAALQSEYSLWTRDPEEDVLATCRELGIGFVPYSPLGRGFLTGAIKTEDLAADDFRRQVPRFQAENFD
ANAALVATLEQLAAEKGVTAAQLALAWVLGQGDDIVPIPGARKLHHLEQNAAAADIVLSAAELDQLGAAIPAAQVAGKRY
SDASLAMTNL
>Mature_330_residues
MKTRKLGNDLAVSAVGLGCMGMSFAYGASDDAESVRTLHRAVELGVTFFDTAEVYGPFTNEALVGKVLKPFRDRVVIATK
FGFKIDTSQQGAAAIAGVDGRPEHVRAVAEASLKRLGIETIDLFYQHRVDPNVPIEETVGVMGELVREGKVRALGLSEAG
SATIRRAHAVHPIAALQSEYSLWTRDPEEDVLATCRELGIGFVPYSPLGRGFLTGAIKTEDLAADDFRRQVPRFQAENFD
ANAALVATLEQLAAEKGVTAAQLALAWVLGQGDDIVPIPGARKLHHLEQNAAAADIVLSAAELDQLGAAIPAAQVAGKRY
SDASLAMTNL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=337, Percent_Identity=29.3768545994065, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI4504825, Length=334, Percent_Identity=29.3413173652695, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI27436971, Length=290, Percent_Identity=32.7586206896552, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI27436964, Length=349, Percent_Identity=28.080229226361, Blast_Score=101, Evalue=9e-22,
Organism=Homo sapiens, GI27436962, Length=349, Percent_Identity=27.7936962750716, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI27436966, Length=349, Percent_Identity=27.7936962750716, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI223718702, Length=316, Percent_Identity=30.6962025316456, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI41327764, Length=284, Percent_Identity=30.2816901408451, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI41152114, Length=315, Percent_Identity=30.4761904761905, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI87081735, Length=337, Percent_Identity=31.4540059347181, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1788070, Length=317, Percent_Identity=34.7003154574132, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1789375, Length=313, Percent_Identity=29.073482428115, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788081, Length=316, Percent_Identity=28.7974683544304, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787674, Length=306, Percent_Identity=27.4509803921569, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789199, Length=334, Percent_Identity=26.3473053892216, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17564128, Length=310, Percent_Identity=22.9032258064516, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6325384, Length=356, Percent_Identity=28.0898876404494, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6319958, Length=295, Percent_Identity=26.7796610169492, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6325169, Length=349, Percent_Identity=25.7879656160458, Blast_Score=109, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6323998, Length=297, Percent_Identity=26.2626262626263, Blast_Score=106, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6322615, Length=253, Percent_Identity=27.6679841897233, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6319951, Length=310, Percent_Identity=26.1290322580645, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24640980, Length=331, Percent_Identity=26.8882175226586, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI45549126, Length=331, Percent_Identity=26.8882175226586, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24646155, Length=164, Percent_Identity=33.5365853658537, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35146; Mature: 35146

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTRKLGNDLAVSAVGLGCMGMSFAYGASDDAESVRTLHRAVELGVTFFDTAEVYGPFTN
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEHHHHCCCCCC
EALVGKVLKPFRDRVVIATKFGFKIDTSQQGAAAIAGVDGRPEHVRAVAEASLKRLGIET
HHHHHHHHHHHHCCEEEEEECCEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCHHH
IDLFYQHRVDPNVPIEETVGVMGELVREGKVRALGLSEAGSATIRRAHAVHPIAALQSEY
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
SLWTRDPEEDVLATCRELGIGFVPYSPLGRGFLTGAIKTEDLAADDFRRQVPRFQAENFD
HHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHCCCCCCCCCC
ANAALVATLEQLAAEKGVTAAQLALAWVLGQGDDIVPIPGARKLHHLEQNAAAADIVLSA
CCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHH
AELDQLGAAIPAAQVAGKRYSDASLAMTNL
HHHHHHHHHCCHHHHCCCCCCCCCEEECCC
>Mature Secondary Structure
MKTRKLGNDLAVSAVGLGCMGMSFAYGASDDAESVRTLHRAVELGVTFFDTAEVYGPFTN
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEHHHHCCCCCC
EALVGKVLKPFRDRVVIATKFGFKIDTSQQGAAAIAGVDGRPEHVRAVAEASLKRLGIET
HHHHHHHHHHHHCCEEEEEECCEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCHHH
IDLFYQHRVDPNVPIEETVGVMGELVREGKVRALGLSEAGSATIRRAHAVHPIAALQSEY
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
SLWTRDPEEDVLATCRELGIGFVPYSPLGRGFLTGAIKTEDLAADDFRRQVPRFQAENFD
HHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHCCCCCCCCCC
ANAALVATLEQLAAEKGVTAAQLALAWVLGQGDDIVPIPGARKLHHLEQNAAAADIVLSA
CCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHH
AELDQLGAAIPAAQVAGKRYSDASLAMTNL
HHHHHHHHHCCHHHHCCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]