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The map label for this gene is pncB

Identifier: 209551709

GI number: 209551709

Start: 4319608

End: 4320912

Strand: Direct

Name: pncB

Synonym: Rleg2_4138

Alternate gene names: 209551709

Gene position: 4319608-4320912 (Clockwise)

Preceding gene: 209551708

Following gene: 209551712

Centisome position: 95.19

GC content: 60.23

Gene sequence:

>1305_bases
ATGGCCAGGACCGATATTGCAAGACGCGTCTACAATCATGCCTGGAAGCTCGATCCGATCATCCGCAGCCTGATCGATAC
CGACTTCTATAAACTCCTGATGCTGCAGATGATCTGGAAGCTCTATCCGGACGTGAACGCATCCTTCACGCTCATCAACC
GCACCAAGCGCGTGCGGCTCGCCGATGAGATCGACGAAGGCGAATTGCGCGAACAGCTCGATCATGCCCGCACGCTGAAA
CTCTCCAAGAAGGAGATGATCTGGCTGGCGGGTAACAGTTTTTACGGCCGCGCGCAGATCTTCGAGCCGGAATTCCTTGC
CTGGCTTTCCAACTTCCAGCTCCCCGAATATGAGCTGTCGAAGAAAGACGGACAGTATGTCCTGGATTTCCACGGGTCGT
GGAAAGAAACCACCATGTGGGAGATCCCAGCACTCGCCATCGTCAACGAGCTGCGGTCGCGTTCGGCGATGAGAGCGCTC
GGTCCCTTCACCCTCGATGTGCTCTATGCCCGCGCCAAGGCGAAGATGTGGTCGAAGGTCGAGCGGCTGAAGGAATTGCC
GGGCTTGCGCATCTCCGATTTCGGCACCCGCCGCCGTCACAGTTTCCTCTGGCAGCGCTGGTGCGTCGAGGCACTGAAGG
AAGGCATCGGCCCGGCCTTTACCGGCACCAGCAATGTCTTGCTGGCGATGGATTCCGATCTCGAGGCCGTCGGCACCAAT
GCGCACGAACTGCCGATGGTGGCTGCCGCCCTTGCGCAAACCGACGAGCAGTTGCGCAACGCGCCCTACAAGATCCTGCG
CGACTGGAACAAGCTCTATGGCGGCAATCTTCTGATCGTCCTGCCGGATGCTTTCGGCACTGCCGCTTTCCTGCGCGACG
CGCCGGAATGGGTCGCTGACTGGACCGGCTTCCGCCCCGACAGCGCCCCGCCGATCGAAGGCGGAGAAAAGATCATCGAC
TGGTGGAAGAAGATGGGCCGCGATCCGCGCCAGAAGCTGCTGATCTTCTCCGACGGTCTTGATGTCGACGCCATCATCGA
CACTTACCGACATTTCGAAGGCCGCGTGCGCATGAGCTTCGGCTGGGGCACCAACCTGACGAATGATTTTTCCGGCTGCG
CGCCGACCGAGATCTCAGGTCTCAATCCGATCTCGGTCGTCTGCAAGGTCAGCGACGCCGACGGCCGCCCGGCGGTAAAA
CTCTCCGACAATCCGCAGAAGGCGACAGGCGACCCGGCAGAGGTCGAGCGCTACCTGAAATTCTTCGGCGCCGAGGACCG
GATCGATCAGACCGTTCTGGTGTAG

Upstream 100 bases:

>100_bases
GATAACAAGGCGCACGAGCCGGTTCGTGCGCCGGCCCGGAACTCGCAAACACCCGGGAATTTGGCAGCACCTGACCGGAG
TGGACAGGGGCAGGGATTTT

Downstream 100 bases:

>100_bases
GCAAGCGACACTGCGCCGCCATCCCGCGGCGCATTGTTATGCCCGGCCATCGCATCCTCGATCGACCAGCCGAAGCGCCA
GGCGTCGAACATCGAGTACC

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MARTDIARRVYNHAWKLDPIIRSLIDTDFYKLLMLQMIWKLYPDVNASFTLINRTKRVRLADEIDEGELREQLDHARTLK
LSKKEMIWLAGNSFYGRAQIFEPEFLAWLSNFQLPEYELSKKDGQYVLDFHGSWKETTMWEIPALAIVNELRSRSAMRAL
GPFTLDVLYARAKAKMWSKVERLKELPGLRISDFGTRRRHSFLWQRWCVEALKEGIGPAFTGTSNVLLAMDSDLEAVGTN
AHELPMVAAALAQTDEQLRNAPYKILRDWNKLYGGNLLIVLPDAFGTAAFLRDAPEWVADWTGFRPDSAPPIEGGEKIID
WWKKMGRDPRQKLLIFSDGLDVDAIIDTYRHFEGRVRMSFGWGTNLTNDFSGCAPTEISGLNPISVVCKVSDADGRPAVK
LSDNPQKATGDPAEVERYLKFFGAEDRIDQTVLV

Sequences:

>Translated_434_residues
MARTDIARRVYNHAWKLDPIIRSLIDTDFYKLLMLQMIWKLYPDVNASFTLINRTKRVRLADEIDEGELREQLDHARTLK
LSKKEMIWLAGNSFYGRAQIFEPEFLAWLSNFQLPEYELSKKDGQYVLDFHGSWKETTMWEIPALAIVNELRSRSAMRAL
GPFTLDVLYARAKAKMWSKVERLKELPGLRISDFGTRRRHSFLWQRWCVEALKEGIGPAFTGTSNVLLAMDSDLEAVGTN
AHELPMVAAALAQTDEQLRNAPYKILRDWNKLYGGNLLIVLPDAFGTAAFLRDAPEWVADWTGFRPDSAPPIEGGEKIID
WWKKMGRDPRQKLLIFSDGLDVDAIIDTYRHFEGRVRMSFGWGTNLTNDFSGCAPTEISGLNPISVVCKVSDADGRPAVK
LSDNPQKATGDPAEVERYLKFFGAEDRIDQTVLV
>Mature_433_residues
ARTDIARRVYNHAWKLDPIIRSLIDTDFYKLLMLQMIWKLYPDVNASFTLINRTKRVRLADEIDEGELREQLDHARTLKL
SKKEMIWLAGNSFYGRAQIFEPEFLAWLSNFQLPEYELSKKDGQYVLDFHGSWKETTMWEIPALAIVNELRSRSAMRALG
PFTLDVLYARAKAKMWSKVERLKELPGLRISDFGTRRRHSFLWQRWCVEALKEGIGPAFTGTSNVLLAMDSDLEAVGTNA
HELPMVAAALAQTDEQLRNAPYKILRDWNKLYGGNLLIVLPDAFGTAAFLRDAPEWVADWTGFRPDSAPPIEGGEKIIDW
WKKMGRDPRQKLLIFSDGLDVDAIIDTYRHFEGRVRMSFGWGTNLTNDFSGCAPTEISGLNPISVVCKVSDADGRPAVKL
SDNPQKATGDPAEVERYLKFFGAEDRIDQTVLV

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family

Homologues:

Organism=Escherichia coli, GI1787162, Length=409, Percent_Identity=34.9633251833741, Blast_Score=199, Evalue=3e-52,
Organism=Saccharomyces cerevisiae, GI6324783, Length=435, Percent_Identity=30.3448275862069, Blast_Score=172, Evalue=8e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PNCB_RHILW (B5ZWU4)

Other databases:

- EMBL:   CP001191
- RefSeq:   YP_002283626.1
- ProteinModelPortal:   B5ZWU4
- SMR:   B5ZWU4
- GeneID:   6982910
- GenomeReviews:   CP001191_GR
- KEGG:   rlt:Rleg2_4138
- HOGENOM:   HBG325503
- OMA:   GNTFYGK
- ProtClustDB:   PRK05321
- GO:   GO:0005737
- HAMAP:   MF_00570
- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638
- PANTHER:   PTHR11098:SF1
- PIRSF:   PIRSF000484
- TIGRFAMs:   TIGR01514

Pfam domain/function: PF04095 NAPRTase; SSF51690 Q_phspho_trans

EC number: =2.4.2.11

Molecular weight: Translated: 49509; Mature: 49378

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARTDIARRVYNHAWKLDPIIRSLIDTDFYKLLMLQMIWKLYPDVNASFTLINRTKRVRL
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHEEE
ADEIDEGELREQLDHARTLKLSKKEMIWLAGNSFYGRAQIFEPEFLAWLSNFQLPEYELS
HHCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEECCHHHHHHHHCCCCCCHHHC
KKDGQYVLDFHGSWKETTMWEIPALAIVNELRSRSAMRALGPFTLDVLYARAKAKMWSKV
CCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
ERLKELPGLRISDFGTRRRHSFLWQRWCVEALKEGIGPAFTGTSNVLLAMDSDLEAVGTN
HHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHCCC
AHELPMVAAALAQTDEQLRNAPYKILRDWNKLYGGNLLIVLPDAFGTAAFLRDAPEWVAD
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCHHHHHH
WTGFRPDSAPPIEGGEKIIDWWKKMGRDPRQKLLIFSDGLDVDAIIDTYRHFEGRVRMSF
CCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHEEEEEECCCCHHHHHHHHHHCCCEEEEEE
GWGTNLTNDFSGCAPTEISGLNPISVVCKVSDADGRPAVKLSDNPQKATGDPAEVERYLK
CCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEECCCCCCCCCCHHHHHHHHH
FFGAEDRIDQTVLV
HHCCCCCCCCCCCC
>Mature Secondary Structure 
ARTDIARRVYNHAWKLDPIIRSLIDTDFYKLLMLQMIWKLYPDVNASFTLINRTKRVRL
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHEEE
ADEIDEGELREQLDHARTLKLSKKEMIWLAGNSFYGRAQIFEPEFLAWLSNFQLPEYELS
HHCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEECCHHHHHHHHCCCCCCHHHC
KKDGQYVLDFHGSWKETTMWEIPALAIVNELRSRSAMRALGPFTLDVLYARAKAKMWSKV
CCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
ERLKELPGLRISDFGTRRRHSFLWQRWCVEALKEGIGPAFTGTSNVLLAMDSDLEAVGTN
HHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHCCC
AHELPMVAAALAQTDEQLRNAPYKILRDWNKLYGGNLLIVLPDAFGTAAFLRDAPEWVAD
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCHHHHHH
WTGFRPDSAPPIEGGEKIIDWWKKMGRDPRQKLLIFSDGLDVDAIIDTYRHFEGRVRMSF
CCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHEEEEEECCCCHHHHHHHHHHCCCEEEEEE
GWGTNLTNDFSGCAPTEISGLNPISVVCKVSDADGRPAVKLSDNPQKATGDPAEVERYLK
CCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEECCCCCCCCCCHHHHHHHHH
FFGAEDRIDQTVLV
HHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA