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The map label for this gene is nudC [H]

Identifier: 209551650

GI number: 209551650

Start: 4255079

End: 4256038

Strand: Direct

Name: nudC [H]

Synonym: Rleg2_4079

Alternate gene names: 209551650

Gene position: 4255079-4256038 (Clockwise)

Preceding gene: 209551649

Following gene: 209551651

Centisome position: 93.77

GC content: 63.75

Gene sequence:

>960_bases
ATGAGTCATTCGCTTTTCGATTCGGATGTGCCGCATCCCGAACCCAGCAATCTCACGGCTTTTGCCGCCAACGACCTCAA
TCGTGATTCCGAGCATCGCGACGAACACTCCGTCGAAAAGGCGCTGGCAAGGGACGGCACCCATATCTTCGCCTTCGCTG
GGGATAAGCTGGTGCTGAAGCATGACGGCCAGGTGCTCGATCCGCTCTTTGCCCGCTACGAGCTGAAGGAATTGCAGCCG
GATTGGGACGAGACGGTGCTTCTCGGCTACCGCAAATCAGGCGAGCCGCGCCTTGCCGTCCCCGTCGGCATCGACGTAGG
GAACCTCGCCAGCCAGTATAAGCCCGCCGACGGCCGCACGCTGTTTCGCGAAATGCTGATCGACGAGGTGCTGCTCGGGG
AATTCGCCCAGGCCGCGAGCCTCATCCGTTGGAATGGCGACAACCGCTTCTGCGGTCGCTGCGGCTCGGCGATGGAGATC
CACATCGGCGGCTACAAGCGTGTCTGCGCCGCCTGCGAACACATGATCTTCCCGCGCACCGACCCCGTCGTCATCATGCT
GACCATCGACGAGAGCCGCGACCTCTGCCTGCTCGGCCGCAGCCCGCATTTCGCGCCCGGCATGTATTCCTGTCTTGCCG
GCTTCGTCGAACCCGGCGAGACCATCGAAAACGCCGTGCGCCGCGAAACGCTGGAGGAATCGGGCATCCGCACCGGCCGC
ATCCGCTACCACGCCTCGCAGCCCTGGCCGATGCCGCATTCGCTGATGATCGGCTGTTACGCCGAGGCCAAATCCACCGA
AATCACCCGCGACGAGACGGAGCTGGAGGATTGCCGCTGGTTCACCCGCGAGGAAACGATCGAGATGCTGGAACGCCCGA
GCGCGACAGGCAAGGCCTCGCCGCCGAAAGGGGCGATCGCCCACCGCTTGATGCGCGACTGGGTGGAGTGGAAGCGGTAA

Upstream 100 bases:

>100_bases
CCAACTGGCCAGGCCCCGTCTGGGGCTTCGGACAGGCGGACCCTTACGAGGACGGAAAGAGAGACGAATTCATAGCGAAG
CTGCGGGAAGCCCTTTCATC

Downstream 100 bases:

>100_bases
CGCCATGCCGGTGGCACGCTCGGAACGGCTGCTGACGCTGCTCCAGACGCTTCGGCGTTACAGGCGGCCGGTGACCGGTA
TGGTGCTGGCCGAGGAGACC

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MSHSLFDSDVPHPEPSNLTAFAANDLNRDSEHRDEHSVEKALARDGTHIFAFAGDKLVLKHDGQVLDPLFARYELKELQP
DWDETVLLGYRKSGEPRLAVPVGIDVGNLASQYKPADGRTLFREMLIDEVLLGEFAQAASLIRWNGDNRFCGRCGSAMEI
HIGGYKRVCAACEHMIFPRTDPVVIMLTIDESRDLCLLGRSPHFAPGMYSCLAGFVEPGETIENAVRRETLEESGIRTGR
IRYHASQPWPMPHSLMIGCYAEAKSTEITRDETELEDCRWFTREETIEMLERPSATGKASPPKGAIAHRLMRDWVEWKR

Sequences:

>Translated_319_residues
MSHSLFDSDVPHPEPSNLTAFAANDLNRDSEHRDEHSVEKALARDGTHIFAFAGDKLVLKHDGQVLDPLFARYELKELQP
DWDETVLLGYRKSGEPRLAVPVGIDVGNLASQYKPADGRTLFREMLIDEVLLGEFAQAASLIRWNGDNRFCGRCGSAMEI
HIGGYKRVCAACEHMIFPRTDPVVIMLTIDESRDLCLLGRSPHFAPGMYSCLAGFVEPGETIENAVRRETLEESGIRTGR
IRYHASQPWPMPHSLMIGCYAEAKSTEITRDETELEDCRWFTREETIEMLERPSATGKASPPKGAIAHRLMRDWVEWKR
>Mature_318_residues
SHSLFDSDVPHPEPSNLTAFAANDLNRDSEHRDEHSVEKALARDGTHIFAFAGDKLVLKHDGQVLDPLFARYELKELQPD
WDETVLLGYRKSGEPRLAVPVGIDVGNLASQYKPADGRTLFREMLIDEVLLGEFAQAASLIRWNGDNRFCGRCGSAMEIH
IGGYKRVCAACEHMIFPRTDPVVIMLTIDESRDLCLLGRSPHFAPGMYSCLAGFVEPGETIENAVRRETLEESGIRTGRI
RYHASQPWPMPHSLMIGCYAEAKSTEITRDETELEDCRWFTREETIEMLERPSATGKASPPKGAIAHRLMRDWVEWKR

Specific function: Unknown

COG id: COG2816

COG function: function code L; NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI13899267, Length=191, Percent_Identity=50.7853403141361, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI50593112, Length=258, Percent_Identity=36.046511627907, Blast_Score=150, Evalue=1e-36,
Organism=Escherichia coli, GI48994995, Length=185, Percent_Identity=36.2162162162162, Blast_Score=111, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI212645999, Length=202, Percent_Identity=35.6435643564356, Blast_Score=114, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI71986510, Length=202, Percent_Identity=35.6435643564356, Blast_Score=114, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6321371, Length=194, Percent_Identity=36.0824742268041, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015375
- InterPro:   IPR022925
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR015376 [H]

Pfam domain/function: PF00293 NUDIX; PF09296 NUDIX-like; PF09297 zf-NADH-PPase [H]

EC number: =3.6.1.22 [H]

Molecular weight: Translated: 36010; Mature: 35879

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHSLFDSDVPHPEPSNLTAFAANDLNRDSEHRDEHSVEKALARDGTHIFAFAGDKLVLK
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCEEEEE
HDGQVLDPLFARYELKELQPDWDETVLLGYRKSGEPRLAVPVGIDVGNLASQYKPADGRT
CCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEECCCHHHHHHHCCCCCHHH
LFREMLIDEVLLGEFAQAASLIRWNGDNRFCGRCGSAMEIHIGGYKRVCAACEHMIFPRT
HHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHCCCCEEEEEECCHHHHHHHHHHHCCCCC
DPVVIMLTIDESRDLCLLGRSPHFAPGMYSCLAGFVEPGETIENAVRRETLEESGIRTGR
CCEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCE
IRYHASQPWPMPHSLMIGCYAEAKSTEITRDETELEDCRWFTREETIEMLERPSATGKAS
EEEECCCCCCCCCHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PPKGAIAHRLMRDWVEWKR
CCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SHSLFDSDVPHPEPSNLTAFAANDLNRDSEHRDEHSVEKALARDGTHIFAFAGDKLVLK
CCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCEEEEE
HDGQVLDPLFARYELKELQPDWDETVLLGYRKSGEPRLAVPVGIDVGNLASQYKPADGRT
CCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEECCCHHHHHHHCCCCCHHH
LFREMLIDEVLLGEFAQAASLIRWNGDNRFCGRCGSAMEIHIGGYKRVCAACEHMIFPRT
HHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHCCCCEEEEEECCHHHHHHHHHHHCCCCC
DPVVIMLTIDESRDLCLLGRSPHFAPGMYSCLAGFVEPGETIENAVRRETLEESGIRTGR
CCEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCE
IRYHASQPWPMPHSLMIGCYAEAKSTEITRDETELEDCRWFTREETIEMLERPSATGKAS
EEEECCCCCCCCCHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PPKGAIAHRLMRDWVEWKR
CCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]