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The map label for this gene is exoB [H]

Identifier: 209551573

GI number: 209551573

Start: 4169478

End: 4170461

Strand: Direct

Name: exoB [H]

Synonym: Rleg2_4002

Alternate gene names: 209551573

Gene position: 4169478-4170461 (Clockwise)

Preceding gene: 209551572

Following gene: 209551574

Centisome position: 91.88

GC content: 63.52

Gene sequence:

>984_bases
ATGCCCCGCTACATTTTGGTTACCGGCGGCGCCGGTTTCATAGGCAGTCATATCTGCAAAACGTTGTCGCGTGCCGGCAT
GGTCCCGGTCACCTACGACAATCTCTCGACCGGGCATGCCGACAGTGTCCGCTGGGGACCGCTTATCCGGGCGGACCTCG
CCGATGCCGCCACGCTGCGCCGGACCCTTGCAGAGTTTTCGCCCGATTGCGTCATCCATTGCGGCGCCAATGCCTATGTC
GGCGAATCCGTCGAAATGCCCAGGAAATATTACCGCAACAACGTCGTCGGCAGCCTGACGCTGCTTGAGGCCTGTCTCGA
CCAGGATATCGACCGGATCGTCTTTTCGAGCAGCTGCGCCACCTATGGCGTCCCCGCCTCGTTGCCGATACGCGAGGAAA
CTCCACAGCACCCGGTCAATCCCTACGGCCGCACCAAGTTGATCTTCGAGATGGCGCTCGAGGATTTTGCCGCCGCCTAT
GGCATCCGCTTCGCCGCGCTGCGCTATTTCAACGCGGCCGGCGCCGATCCGGACGGCGAGCTTGCCGAGCGCCACCATCC
GGAAACCCATCTCATCCCCCGCGCCCTTCTCGCTGCCGCCGGCAGGCTGGAGCGGCTCGATGTCTTCGGCACCGATTATC
CCACAGAAGACGGAACCTGTGTGCGTGACTATATTCATGTCAGCGATCTCGCCCAGGCGCATCTTGCCGCCGTCAATCAC
CTGATGGCCGACGGCGATTCGCTCAGCGTCAATCTCGGCTCCGGCCGCGGCACCTCGGTGCGCCAGATCCTCGAAGCCAT
CTATCGTGCGACCGGTCGTGAGGTTCCCGTCCGGTATCGTCCCCGCCGGGCCGGCGATCCGCCGATCCTCTTTGCCGACA
CGGCAAAAGCCAGGGCGGAACTCGGCTTCGCGCCCGCTCTCTCGGATATCGATACGATCATCCGCACCGCCGGTCCCACC
TTCGGGCTGGAGGTGAAGGCATGA

Upstream 100 bases:

>100_bases
GGCTGGCAGCCCTGCATCGGGCTTGAAACCGGTCTGGCGCGCACCGTCGATTATTTCGACGGCTTGCTTGCCGGCGCCGA
GAAGGCGGAGGCCGTATGAG

Downstream 100 bases:

>100_bases
GCATCGGTTCGGAAATCGGTCAACGCGCCAGGACGGCGAAAGCTGCCTCCGCGAATGCTTTCGATGCTGTCTTCGCCGGC
TGGAGCCGCGTCGTTTACGG

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MPRYILVTGGAGFIGSHICKTLSRAGMVPVTYDNLSTGHADSVRWGPLIRADLADAATLRRTLAEFSPDCVIHCGANAYV
GESVEMPRKYYRNNVVGSLTLLEACLDQDIDRIVFSSSCATYGVPASLPIREETPQHPVNPYGRTKLIFEMALEDFAAAY
GIRFAALRYFNAAGADPDGELAERHHPETHLIPRALLAAAGRLERLDVFGTDYPTEDGTCVRDYIHVSDLAQAHLAAVNH
LMADGDSLSVNLGSGRGTSVRQILEAIYRATGREVPVRYRPRRAGDPPILFADTAKARAELGFAPALSDIDTIIRTAGPT
FGLEVKA

Sequences:

>Translated_327_residues
MPRYILVTGGAGFIGSHICKTLSRAGMVPVTYDNLSTGHADSVRWGPLIRADLADAATLRRTLAEFSPDCVIHCGANAYV
GESVEMPRKYYRNNVVGSLTLLEACLDQDIDRIVFSSSCATYGVPASLPIREETPQHPVNPYGRTKLIFEMALEDFAAAY
GIRFAALRYFNAAGADPDGELAERHHPETHLIPRALLAAAGRLERLDVFGTDYPTEDGTCVRDYIHVSDLAQAHLAAVNH
LMADGDSLSVNLGSGRGTSVRQILEAIYRATGREVPVRYRPRRAGDPPILFADTAKARAELGFAPALSDIDTIIRTAGPT
FGLEVKA
>Mature_326_residues
PRYILVTGGAGFIGSHICKTLSRAGMVPVTYDNLSTGHADSVRWGPLIRADLADAATLRRTLAEFSPDCVIHCGANAYVG
ESVEMPRKYYRNNVVGSLTLLEACLDQDIDRIVFSSSCATYGVPASLPIREETPQHPVNPYGRTKLIFEMALEDFAAAYG
IRFAALRYFNAAGADPDGELAERHHPETHLIPRALLAAAGRLERLDVFGTDYPTEDGTCVRDYIHVSDLAQAHLAAVNHL
MADGDSLSVNLGSGRGTSVRQILEAIYRATGREVPVRYRPRRAGDPPILFADTAKARAELGFAPALSDIDTIIRTAGPTF
GLEVKA

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=326, Percent_Identity=38.9570552147239, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI56118217, Length=326, Percent_Identity=38.9570552147239, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI189083684, Length=326, Percent_Identity=38.9570552147239, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI42516563, Length=311, Percent_Identity=25.4019292604502, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1786974, Length=312, Percent_Identity=39.4230769230769, Blast_Score=205, Evalue=4e-54,
Organism=Escherichia coli, GI1790049, Length=325, Percent_Identity=28.3076923076923, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI48994969, Length=252, Percent_Identity=31.3492063492063, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1788366, Length=347, Percent_Identity=24.4956772334294, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788353, Length=257, Percent_Identity=29.5719844357977, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71982035, Length=321, Percent_Identity=38.3177570093458, Blast_Score=204, Evalue=7e-53,
Organism=Caenorhabditis elegans, GI71982038, Length=323, Percent_Identity=37.7708978328173, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17568069, Length=336, Percent_Identity=26.4880952380952, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319493, Length=331, Percent_Identity=39.8791540785499, Blast_Score=218, Evalue=1e-57,
Organism=Drosophila melanogaster, GI19923002, Length=322, Percent_Identity=37.2670807453416, Blast_Score=198, Evalue=4e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35426; Mature: 35294

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRYILVTGGAGFIGSHICKTLSRAGMVPVTYDNLSTGHADSVRWGPLIRADLADAATLR
CCCEEEEECCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHH
RTLAEFSPDCVIHCGANAYVGESVEMPRKYYRNNVVGSLTLLEACLDQDIDRIVFSSSCA
HHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
TYGVPASLPIREETPQHPVNPYGRTKLIFEMALEDFAAAYGIRFAALRYFNAAGADPDGE
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
LAERHHPETHLIPRALLAAAGRLERLDVFGTDYPTEDGTCVRDYIHVSDLAQAHLAAVNH
HHHHCCCCHHHHHHHHHHHHCCHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LMADGDSLSVNLGSGRGTSVRQILEAIYRATGREVPVRYRPRRAGDPPILFADTAKARAE
HHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCEEEECCHHHHHH
LGFAPALSDIDTIIRTAGPTFGLEVKA
CCCCCCHHHHHHHHHHCCCCCCEEECC
>Mature Secondary Structure 
PRYILVTGGAGFIGSHICKTLSRAGMVPVTYDNLSTGHADSVRWGPLIRADLADAATLR
CCEEEEECCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHH
RTLAEFSPDCVIHCGANAYVGESVEMPRKYYRNNVVGSLTLLEACLDQDIDRIVFSSSCA
HHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
TYGVPASLPIREETPQHPVNPYGRTKLIFEMALEDFAAAYGIRFAALRYFNAAGADPDGE
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
LAERHHPETHLIPRALLAAAGRLERLDVFGTDYPTEDGTCVRDYIHVSDLAQAHLAAVNH
HHHHCCCCHHHHHHHHHHHHCCHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LMADGDSLSVNLGSGRGTSVRQILEAIYRATGREVPVRYRPRRAGDPPILFADTAKARAE
HHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCEEEECCHHHHHH
LGFAPALSDIDTIIRTAGPTFGLEVKA
CCCCCCHHHHHHHHHHCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9236769 [H]