Click here to switch to the map view.

The map label for this gene is chvG [H]

Identifier: 209551539

GI number: 209551539

Start: 4121956

End: 4123746

Strand: Reverse

Name: chvG [H]

Synonym: Rleg2_3968

Alternate gene names: 209551539

Gene position: 4123746-4121956 (Counterclockwise)

Preceding gene: 209551540

Following gene: 209551538

Centisome position: 90.87

GC content: 63.32

Gene sequence:

>1791_bases
TTGGCACAGTTGGTGCAGGAAAGGGATCTCGACGATGCGGAGGGCGTGAGCACCCGTCGCGTCCGAGGCCGCCGTTGGTC
GCATCCCTTCACGCTGATCCGCCGCATCTTCGGCAATGCCGTGTTTTCGAGCCTGACGCGACGCATCGTCTTCTTCAATC
TCGTCGCACTGCTGGTGCTCGTCGGCGGTATCCTCTACCTCAACCAGTTTCGCGAGGGGCTGATCGACGCCCGCGCCGAG
AGCCTTTTGACGCAAGGCGAGATCATCGCCGGCGCCATTTCGGCTTCCGCATCGGTCGATACGAACTCGATCACCATCGA
TCCGCAGAAGCTGCTCGAGCTGCAGGCCGGCCAGAGCATCACCCCGGTACCGAACGACGAAGACCTCGAATTCCCGATCG
ATCCCGAGAAGGTCGCGCCGGTGCTGCGCCGGCTGATCTCTCCGACGCGCACGCGCGCCCGCATCTTCGATGCCGATGCC
AATCTGCTGCTGGATTCCCGTCATCTTTATTCGCGCGGCCAGGTGCTGCGTTTCGACCTGCCGCCGGTCGAGGAGGAGAA
GCAGACCTGGAGCGAATGGTTCGCCACCCTGTTCAACAAGGCGCTGCAGCCGGGCAACCTGCCGCTCTACAAGGAAGCGC
CGGGCGGCGACGGCTCGATCTATCCGGAAGTGATGAACGCGCTTACCGGCGTGCGCGGCGCCGTCGTGCGCACGACCGAA
AAAGGCGAACTCATCGTTTCGGTCGCCGTGCCGATCCAGCGTTTCCGCGCCGTGCTCGGGGTGCTGCTGCTGTCGACACA
GGCTGGAGACATCGACAATATCGTTCATGCCGAGCGGCTTGCGATCATGCGCGTCTTCGGCGTCGCGACGCTCGTCAACG
TGCTGCTTTCGCTGGTGCTCTCGTCGACGATCGCCAATCCGCTGCGCCGCCTTTCGGCCGCCGCCATCCGGGTGCGCCGC
GGAGCCAAGACACGTGAGCAGATTCCTGACTTCTCCGCCCGCCAGGATGAAATCGGCAATCTTTCCATTGCATTGCGCGA
AATGACGACGGCGCTCTACGACCGCATCGATGCGATCGAGAGTTTCGCCGCCGATGTCAGCCACGAACTCAAGAATCCGC
TGACGTCGCTGCGTAGCGCCGTCGAAACGCTGCCGCTTGCCCGATCCGACGATTCCAAGAAACGGCTGATGGACGTCATC
CAGCACGATGTCCGCCGCCTCGACCGGCTGATCAGCGATATCTCCGACGCCTCGCGCCTCGATGCCGAGCTTGCTCGCGT
CGATGCCGGTTCCGTCGACATGGAGGTGCTGTTGCGCGACCTCATCGAGGTTTCGCGCCAGGTCAGGAGCACCAAGAAGC
AGGTGGAGATCGAATATGCGATCGACCGCAAGCCGAACGTCAAGACCCGCTTCGTCGTTACCGGCCACGACCTGCGCATC
GGCCAGATCATCGCCAACCTGATCGAGAACGCCCGCTCCTTCGTGCCGGAGAAGGGTGGCAAGATTACCGTGCGGCTGGT
TCGGACACGGTCGCGCTGCGTCACCACGATCGAAGACAACGGCCCCGGCATCCAGGCGGAAAATATCGACCGCATCTTCG
AGCGCTTCTATACCGACCGGCCGGAATCGGAAGGCTTCGGCCAGAATTCGGGCCTCGGCCTGTCGATCAGCCGCCAGATC
GCTGAGGCTCATGGCGGCTCGCTGCGAGCGGAGAACATCACCGACGCCGAAGGCGGGCAGGTGCTCGGTGCCCGCTTTAT
CCTCGCTTTACCAGTCGATGCCGCCGCATGA

Upstream 100 bases:

>100_bases
CGCTTCCGCGAAGCAGCCTGAGCCCAAACGGCGCAGCGCGAGACATTGTTGAGGGCTGCGGGCCGGTTTATCCGGCCCCG
CCCTTCGAAAGGGCCAGTCG

Downstream 100 bases:

>100_bases
CGGCGGCCCAGAACATCCATGCGACGGCGATCGTCGTCGGCAGGACGGGGCTCCTGTTCAGCGGTCCCTCCGGCTGGGGA
AAATCGATGCTCGCCTTCAC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 596; Mature: 595

Protein sequence:

>596_residues
MAQLVQERDLDDAEGVSTRRVRGRRWSHPFTLIRRIFGNAVFSSLTRRIVFFNLVALLVLVGGILYLNQFREGLIDARAE
SLLTQGEIIAGAISASASVDTNSITIDPQKLLELQAGQSITPVPNDEDLEFPIDPEKVAPVLRRLISPTRTRARIFDADA
NLLLDSRHLYSRGQVLRFDLPPVEEEKQTWSEWFATLFNKALQPGNLPLYKEAPGGDGSIYPEVMNALTGVRGAVVRTTE
KGELIVSVAVPIQRFRAVLGVLLLSTQAGDIDNIVHAERLAIMRVFGVATLVNVLLSLVLSSTIANPLRRLSAAAIRVRR
GAKTREQIPDFSARQDEIGNLSIALREMTTALYDRIDAIESFAADVSHELKNPLTSLRSAVETLPLARSDDSKKRLMDVI
QHDVRRLDRLISDISDASRLDAELARVDAGSVDMEVLLRDLIEVSRQVRSTKKQVEIEYAIDRKPNVKTRFVVTGHDLRI
GQIIANLIENARSFVPEKGGKITVRLVRTRSRCVTTIEDNGPGIQAENIDRIFERFYTDRPESEGFGQNSGLGLSISRQI
AEAHGGSLRAENITDAEGGQVLGARFILALPVDAAA

Sequences:

>Translated_596_residues
MAQLVQERDLDDAEGVSTRRVRGRRWSHPFTLIRRIFGNAVFSSLTRRIVFFNLVALLVLVGGILYLNQFREGLIDARAE
SLLTQGEIIAGAISASASVDTNSITIDPQKLLELQAGQSITPVPNDEDLEFPIDPEKVAPVLRRLISPTRTRARIFDADA
NLLLDSRHLYSRGQVLRFDLPPVEEEKQTWSEWFATLFNKALQPGNLPLYKEAPGGDGSIYPEVMNALTGVRGAVVRTTE
KGELIVSVAVPIQRFRAVLGVLLLSTQAGDIDNIVHAERLAIMRVFGVATLVNVLLSLVLSSTIANPLRRLSAAAIRVRR
GAKTREQIPDFSARQDEIGNLSIALREMTTALYDRIDAIESFAADVSHELKNPLTSLRSAVETLPLARSDDSKKRLMDVI
QHDVRRLDRLISDISDASRLDAELARVDAGSVDMEVLLRDLIEVSRQVRSTKKQVEIEYAIDRKPNVKTRFVVTGHDLRI
GQIIANLIENARSFVPEKGGKITVRLVRTRSRCVTTIEDNGPGIQAENIDRIFERFYTDRPESEGFGQNSGLGLSISRQI
AEAHGGSLRAENITDAEGGQVLGARFILALPVDAAA
>Mature_595_residues
AQLVQERDLDDAEGVSTRRVRGRRWSHPFTLIRRIFGNAVFSSLTRRIVFFNLVALLVLVGGILYLNQFREGLIDARAES
LLTQGEIIAGAISASASVDTNSITIDPQKLLELQAGQSITPVPNDEDLEFPIDPEKVAPVLRRLISPTRTRARIFDADAN
LLLDSRHLYSRGQVLRFDLPPVEEEKQTWSEWFATLFNKALQPGNLPLYKEAPGGDGSIYPEVMNALTGVRGAVVRTTEK
GELIVSVAVPIQRFRAVLGVLLLSTQAGDIDNIVHAERLAIMRVFGVATLVNVLLSLVLSSTIANPLRRLSAAAIRVRRG
AKTREQIPDFSARQDEIGNLSIALREMTTALYDRIDAIESFAADVSHELKNPLTSLRSAVETLPLARSDDSKKRLMDVIQ
HDVRRLDRLISDISDASRLDAELARVDAGSVDMEVLLRDLIEVSRQVRSTKKQVEIEYAIDRKPNVKTRFVVTGHDLRIG
QIIANLIENARSFVPEKGGKITVRLVRTRSRCVTTIEDNGPGIQAENIDRIFERFYTDRPESEGFGQNSGLGLSISRQIA
EAHGGSLRAENITDAEGGQVLGARFILALPVDAAA

Specific function: Member of a two-component regulatory system ChvG/ChvI. Activates ChvI by phosphorylation (Potential) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=246, Percent_Identity=31.3008130081301, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1786783, Length=260, Percent_Identity=28.4615384615385, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1790861, Length=374, Percent_Identity=26.2032085561497, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1788393, Length=269, Percent_Identity=26.3940520446097, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787894, Length=320, Percent_Identity=25.3125, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1790346, Length=306, Percent_Identity=27.4509803921569, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790436, Length=242, Percent_Identity=24.7933884297521, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1788279, Length=302, Percent_Identity=25.4966887417219, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1789403, Length=292, Percent_Identity=29.1095890410959, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI48994928, Length=238, Percent_Identity=25.2100840336134, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1788549, Length=266, Percent_Identity=24.812030075188, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081816, Length=278, Percent_Identity=27.6978417266187, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789808, Length=293, Percent_Identity=27.9863481228669, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI145693157, Length=252, Percent_Identity=25, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790551, Length=248, Percent_Identity=27.8225806451613, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 65850; Mature: 65719

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQLVQERDLDDAEGVSTRRVRGRRWSHPFTLIRRIFGNAVFSSLTRRIVFFNLVALLVL
CCCHHHHCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGGILYLNQFREGLIDARAESLLTQGEIIAGAISASASVDTNSITIDPQKLLELQAGQSI
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEECHHHHHHHHCCCCC
TPVPNDEDLEFPIDPEKVAPVLRRLISPTRTRARIFDADANLLLDSRHLYSRGQVLRFDL
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHEEEECCCCCEECCHHHHCCCCEEEECC
PPVEEEKQTWSEWFATLFNKALQPGNLPLYKEAPGGDGSIYPEVMNALTGVRGAVVRTTE
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCHHHHHHHHHCCCCCEEEECC
KGELIVSVAVPIQRFRAVLGVLLLSTQAGDIDNIVHAERLAIMRVFGVATLVNVLLSLVL
CCCEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSTIANPLRRLSAAAIRVRRGAKTREQIPDFSARQDEIGNLSIALREMTTALYDRIDAIE
HHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHH
SFAADVSHELKNPLTSLRSAVETLPLARSDDSKKRLMDVIQHDVRRLDRLISDISDASRL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAELARVDAGSVDMEVLLRDLIEVSRQVRSTKKQVEIEYAIDRKPNVKTRFVVTGHDLRI
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCEEEEEECCCCHH
GQIIANLIENARSFVPEKGGKITVRLVRTRSRCVTTIEDNGPGIQAENIDRIFERFYTDR
HHHHHHHHHHHHHHCCCCCCEEEEEEEECHHHHEEEEECCCCCCCHHHHHHHHHHHHCCC
PESEGFGQNSGLGLSISRQIAEAHGGSLRAENITDAEGGQVLGARFILALPVDAAA
CCCCCCCCCCCCCCHHHHHHHHHCCCCEECCCCCCCCCCCCHHHHEEEEECCCCCC
>Mature Secondary Structure 
AQLVQERDLDDAEGVSTRRVRGRRWSHPFTLIRRIFGNAVFSSLTRRIVFFNLVALLVL
CCHHHHCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGGILYLNQFREGLIDARAESLLTQGEIIAGAISASASVDTNSITIDPQKLLELQAGQSI
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEECHHHHHHHHCCCCC
TPVPNDEDLEFPIDPEKVAPVLRRLISPTRTRARIFDADANLLLDSRHLYSRGQVLRFDL
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHEEEECCCCCEECCHHHHCCCCEEEECC
PPVEEEKQTWSEWFATLFNKALQPGNLPLYKEAPGGDGSIYPEVMNALTGVRGAVVRTTE
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCHHHHHHHHHCCCCCEEEECC
KGELIVSVAVPIQRFRAVLGVLLLSTQAGDIDNIVHAERLAIMRVFGVATLVNVLLSLVL
CCCEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSTIANPLRRLSAAAIRVRRGAKTREQIPDFSARQDEIGNLSIALREMTTALYDRIDAIE
HHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHH
SFAADVSHELKNPLTSLRSAVETLPLARSDDSKKRLMDVIQHDVRRLDRLISDISDASRL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAELARVDAGSVDMEVLLRDLIEVSRQVRSTKKQVEIEYAIDRKPNVKTRFVVTGHDLRI
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCEEEEEECCCCHH
GQIIANLIENARSFVPEKGGKITVRLVRTRSRCVTTIEDNGPGIQAENIDRIFERFYTDR
HHHHHHHHHHHHHHCCCCCCEEEEEEEECHHHHEEEEECCCCCCCHHHHHHHHHHHHCCC
PESEGFGQNSGLGLSISRQIAEAHGGSLRAENITDAEGGQVLGARFILALPVDAAA
CCCCCCCCCCCCCCHHHHHHHHHCCCCEECCCCCCCCCCCCHHHHEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8407839; 11743193; 11743194 [H]