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The map label for this gene is aroE [H]

Identifier: 209551508

GI number: 209551508

Start: 4087732

End: 4088589

Strand: Direct

Name: aroE [H]

Synonym: Rleg2_3937

Alternate gene names: 209551508

Gene position: 4087732-4088589 (Clockwise)

Preceding gene: 209551507

Following gene: 209551509

Centisome position: 90.08

GC content: 62.82

Gene sequence:

>858_bases
ATGGGTGATTCACGTGAAACATTCGGGCCGAAAGCGTTTGTCACGGGCTTTCCGGTCAAGCATTCGCGCTCGCCGTTGAT
CCACGGATATTGGCTGAAGACGCTCGGCCTGCCAGGCAGCTATCGCGCCCATGAAGTGGCGCCCGAGGCCTTTGCCGATT
TCATCGCTTCGCTGAAGGATGGCAGTTCCGGCTTTACCGGCGGCAATGTCACCATTCCCCACAAGGAACTGGCTTTCCGT
CTCGCCGACAAGCCAGACGAACTATCGCACGAGCTCGGCGCCTCGAACACGCTTTGGCTGGACGATGGCCTGCTGCATGC
GACGAACACCGACGGCCGCGGCTTCACCGCCAATCTCGACGAACGCCATCCGGGCTGGGACCGCCAGGACACGGCGGTCG
TCTTTGGCGCCGGCGGCGCCAGCCGGGCGATCATCCAGGCGGTTCGTGATCGTGGTTTCAAGACGATCCACGTCGTCAAC
CGCACCGTCGAACGCGCCCGTGAACTGGCCGATCGCTTTGGCCCGAAAGTTCAGGCCCACCCGATCGGCGCCCTGGCCGA
AGTGATGAAAGGCGCCGGTCTGTTCATCAATACCACCTCGCTCGGCATGGATGGCGAGGCCGCACCCCAGCTCGATTTCA
CCCCTCTTGCGGCTGAGGCCGTCGTCACCGATATCGTCTATGTCCCCCTGAAGACGCCGATCCTGGCGCAGGCGCAAGAG
CAGGGATTTCCGATCGTCGATGGTCTCGGCATGCTGCTGCATCAGGCCGTGCCGGGATTCGAAAAATGGTTCGGCAAGCG
TCCTGCGGTCGACGCGGCGCTGCGCGCGCTGATCATCGCCGATATGGAAGCACACTGA

Upstream 100 bases:

>100_bases
GGCATCCAGCTGTTCGAGAAAATCGAAGGTGATTATTTCACCATTCTCGGCCTGCCGATGCTGACGCTTCTGGAAAAATT
ACGAGACCTCGGAGCGATCG

Downstream 100 bases:

>100_bases
ATGCTGAAGATCGGACTGACCGGCTCCATCGGTATGGGAAAATCGACGGCGGGCAAGCTCTTTGCCGAGGCGGGGATCCC
ACTGAACGATTCGGATGCCG

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MGDSRETFGPKAFVTGFPVKHSRSPLIHGYWLKTLGLPGSYRAHEVAPEAFADFIASLKDGSSGFTGGNVTIPHKELAFR
LADKPDELSHELGASNTLWLDDGLLHATNTDGRGFTANLDERHPGWDRQDTAVVFGAGGASRAIIQAVRDRGFKTIHVVN
RTVERARELADRFGPKVQAHPIGALAEVMKGAGLFINTTSLGMDGEAAPQLDFTPLAAEAVVTDIVYVPLKTPILAQAQE
QGFPIVDGLGMLLHQAVPGFEKWFGKRPAVDAALRALIIADMEAH

Sequences:

>Translated_285_residues
MGDSRETFGPKAFVTGFPVKHSRSPLIHGYWLKTLGLPGSYRAHEVAPEAFADFIASLKDGSSGFTGGNVTIPHKELAFR
LADKPDELSHELGASNTLWLDDGLLHATNTDGRGFTANLDERHPGWDRQDTAVVFGAGGASRAIIQAVRDRGFKTIHVVN
RTVERARELADRFGPKVQAHPIGALAEVMKGAGLFINTTSLGMDGEAAPQLDFTPLAAEAVVTDIVYVPLKTPILAQAQE
QGFPIVDGLGMLLHQAVPGFEKWFGKRPAVDAALRALIIADMEAH
>Mature_284_residues
GDSRETFGPKAFVTGFPVKHSRSPLIHGYWLKTLGLPGSYRAHEVAPEAFADFIASLKDGSSGFTGGNVTIPHKELAFRL
ADKPDELSHELGASNTLWLDDGLLHATNTDGRGFTANLDERHPGWDRQDTAVVFGAGGASRAIIQAVRDRGFKTIHVVNR
TVERARELADRFGPKVQAHPIGALAEVMKGAGLFINTTSLGMDGEAAPQLDFTPLAAEAVVTDIVYVPLKTPILAQAQEQ
GFPIVDGLGMLLHQAVPGFEKWFGKRPAVDAALRALIIADMEAH

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=266, Percent_Identity=34.5864661654135, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1789675, Length=273, Percent_Identity=36.2637362637363, Blast_Score=114, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6320332, Length=283, Percent_Identity=28.6219081272085, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 30650; Mature: 30519

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDSRETFGPKAFVTGFPVKHSRSPLIHGYWLKTLGLPGSYRAHEVAPEAFADFIASLKD
CCCCCCCCCCCEEEECCCCCCCCCCCEEHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHCC
GSSGFTGGNVTIPHKELAFRLADKPDELSHELGASNTLWLDDGLLHATNTDGRGFTANLD
CCCCCCCCCEEECHHHHHHHHCCCCHHHHHHHCCCCEEEECCCEEEEECCCCCCEECCCC
ERHPGWDRQDTAVVFGAGGASRAIIQAVRDRGFKTIHVVNRTVERARELADRFGPKVQAH
CCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHCCCEECC
PIGALAEVMKGAGLFINTTSLGMDGEAAPQLDFTPLAAEAVVTDIVYVPLKTPILAQAQE
CHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHEEECCCCCHHHHHHH
QGFPIVDGLGMLLHQAVPGFEKWFGKRPAVDAALRALIIADMEAH
CCCCHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GDSRETFGPKAFVTGFPVKHSRSPLIHGYWLKTLGLPGSYRAHEVAPEAFADFIASLKD
CCCCCCCCCCEEEECCCCCCCCCCCEEHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHCC
GSSGFTGGNVTIPHKELAFRLADKPDELSHELGASNTLWLDDGLLHATNTDGRGFTANLD
CCCCCCCCCEEECHHHHHHHHCCCCHHHHHHHCCCCEEEECCCEEEEECCCCCCEECCCC
ERHPGWDRQDTAVVFGAGGASRAIIQAVRDRGFKTIHVVNRTVERARELADRFGPKVQAH
CCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHCCCEECC
PIGALAEVMKGAGLFINTTSLGMDGEAAPQLDFTPLAAEAVVTDIVYVPLKTPILAQAQE
CHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHEEECCCCCHHHHHHH
QGFPIVDGLGMLLHQAVPGFEKWFGKRPAVDAALRALIIADMEAH
CCCCHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA