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The map label for this gene is rlmH [H]

Identifier: 209551454

GI number: 209551454

Start: 4023744

End: 4024226

Strand: Direct

Name: rlmH [H]

Synonym: Rleg2_3883

Alternate gene names: 209551454

Gene position: 4023744-4024226 (Clockwise)

Preceding gene: 209551453

Following gene: 209551455

Centisome position: 88.67

GC content: 62.94

Gene sequence:

>483_bases
ATGCGAATTGGTCTTTTTGCGGTGGGACGGCTGAAATCCGGCCCCGAAAAGGATCTTGCGGCCCGTTATTTCGACCGTTT
CGCCAAGGCCGGCCCTGCCGTCGGCCTCGAACTTGCCCGTGTTGCCGAAGTGGCAGAAAGCCGCGCCTCCAATGCGGAAA
CCCGCAAGCGCGAGGAAGCGGCGATGCTTCTGAAATCGCTTGCCGATGGCAGCATCCTCATTCTTCTCGACGAACGCGGC
AAGGCGCTCGACAGCGAAGCCTTCGCCAGCCTGCTCGGCTCCTATCGCGACCAGGGCAAACGTGACCTGACGATCGCCAT
CGGCGGTGCCGACGGCCTCGATCCTTCCCTCTACGACCGTGCCGACGCCACGCTTTGCCTGGGCAAGATGACCTGGCCGC
ATCAGCTCGTGCGCATACTGATCGCCGAACAGCTCTATCGCGCCGTGACCATCCTGTCCGGCCACCCCTATCACCGCGTC
TGA

Upstream 100 bases:

>100_bases
TCTGTCCGGCGCCTGAGCGTGGCATTGGCTGGCCGGAGACATGAAAACCGGCCGGCGGCGCCTTGTGCGCCCGATGTGCC
GCATCAGCGGGAGCGGATGA

Downstream 100 bases:

>100_bases
TGCCGCATCGCTCGCCAATTCGCATGGTCACGCAGCCGTGTTCCGCCTGCCGGCCGTTGGCCTTCAAACTTTCTGGCAAA
GCGCGCCAAATCAGCTTAGT

Product: rRNA large subunit methyltransferase

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase; rRNA (pseudouridine-N3-)-methyltransferase rlmH [H]

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MRIGLFAVGRLKSGPEKDLAARYFDRFAKAGPAVGLELARVAEVAESRASNAETRKREEAAMLLKSLADGSILILLDERG
KALDSEAFASLLGSYRDQGKRDLTIAIGGADGLDPSLYDRADATLCLGKMTWPHQLVRILIAEQLYRAVTILSGHPYHRV

Sequences:

>Translated_160_residues
MRIGLFAVGRLKSGPEKDLAARYFDRFAKAGPAVGLELARVAEVAESRASNAETRKREEAAMLLKSLADGSILILLDERG
KALDSEAFASLLGSYRDQGKRDLTIAIGGADGLDPSLYDRADATLCLGKMTWPHQLVRILIAEQLYRAVTILSGHPYHRV
>Mature_160_residues
MRIGLFAVGRLKSGPEKDLAARYFDRFAKAGPAVGLELARVAEVAESRASNAETRKREEAAMLLKSLADGSILILLDERG
KALDSEAFASLLGSYRDQGKRDLTIAIGGADGLDPSLYDRADATLCLGKMTWPHQLVRILIAEQLYRAVTILSGHPYHRV

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA [H]

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family [H]

Homologues:

Organism=Escherichia coli, GI1786855, Length=162, Percent_Identity=35.1851851851852, Blast_Score=84, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003742 [H]

Pfam domain/function: PF02590 SPOUT_MTase [H]

EC number: NA

Molecular weight: Translated: 17438; Mature: 17438

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIGLFAVGRLKSGPEKDLAARYFDRFAKAGPAVGLELARVAEVAESRASNAETRKREEA
CCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHH
AMLLKSLADGSILILLDERGKALDSEAFASLLGSYRDQGKRDLTIAIGGADGLDPSLYDR
HHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHH
ADATLCLGKMTWPHQLVRILIAEQLYRAVTILSGHPYHRV
CCHHEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRIGLFAVGRLKSGPEKDLAARYFDRFAKAGPAVGLELARVAEVAESRASNAETRKREEA
CCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHH
AMLLKSLADGSILILLDERGKALDSEAFASLLGSYRDQGKRDLTIAIGGADGLDPSLYDR
HHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHH
ADATLCLGKMTWPHQLVRILIAEQLYRAVTILSGHPYHRV
CCHHEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA