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The map label for this gene is exoB [H]

Identifier: 209551430

GI number: 209551430

Start: 4002788

End: 4003771

Strand: Reverse

Name: exoB [H]

Synonym: Rleg2_3859

Alternate gene names: 209551430

Gene position: 4003771-4002788 (Counterclockwise)

Preceding gene: 209551433

Following gene: 209551429

Centisome position: 88.23

GC content: 62.09

Gene sequence:

>984_bases
ATGGCAGGTGAAACGGTTCTTGTGGTCGGCGGCGCCGGTTATATCGGCTCGCATACGTGTCTCGACCTGGCGAACAAGGG
CTACAAGCCTGTCGTCTTCGATAATTTTTCGAACGGCCATCGCGAGTTCGTCAAATGGGGACCGGCCGAGGAAGGCGATA
TTCGCGACCGCGCCCGGCTGGACGAGGTGCTGGCCAAGCACAAGCCGGCGGCGATCCTGCATTTCGCGGCGCTGATCGAG
GTCGGCGAATCGGTCAAGGATCCGGTTTCCTTCTACGAGAACAACGTCATCGGCACGTTGACGCTGCTTTCGGCGGCGCA
GGCAGCCGGCATCAACGCCTTCGTCTTTTCCTCCACCTGCGCCACCTATGGCCTGCCACAGAGCGTGCCGCTCGACGAGA
CGCACCGGCAGGTGCCGATAAACCCCTACGGGCGGACGAAATATATCGTCGAACAGGCGCTCGCCGATTACGACCAGTAC
AGAAGCCTGCGCTCGGTCGTGCTGCGTTATTTCAATGCGGCGGGTGCTGATTTCGAAGGCCGGATCGGCGAATGGCACCA
GCCGGAGACGCATGCGATCCCGCTGGCGATCGACGCGGCACTCGGCCGCCGCCAGGGCTTCAAGGTGTTCGGCAGCGATT
ACGAGACCCGCGACGGCACCTGCGTGCGCGACTATATCCATGTGCTGGATCTTGCCGATGCGCATGTGCGCGCCGTCGAA
TATCTGTTGAAGGGCGGCGAGTCCGTCGCGCTCAACCTCGGCACCGGCACCGGCACGACGGTCAAGGAATTGCTCGGGGC
GATCGAGGATGTGTCGAACCGGCCTTTCCCGGTCGAGTATATTGGCCGGCGCGAAGGCGATTCGCATACGCTGGTCGCCA
ATAACGACAAGGCGCGCGATGTGCTCGGCTGGGTGCCGCAGTATGATCTCTCCCAGATCATCCGCTCCGCCTGGGACTGG
CATGCAAAATCCAACCAGCATTGA

Upstream 100 bases:

>100_bases
TTTGACGTATTGACCGTTCACGCCTATCGCAATTCCTTCTTTTTATTGACGTGTATCTCGTCTAGGTTTCTTTCATCTCT
CGCTAATAATAGGGTGGTGC

Downstream 100 bases:

>100_bases
GCCCAGAATTGAGAAGACGCGCCGGCCGAACATTCTGCTGATCACCGCCGATCAGTGGCGCGGCGACTGCCTGTCGGCCA
TCGGTCATGCTTGTGTGAAA

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MAGETVLVVGGAGYIGSHTCLDLANKGYKPVVFDNFSNGHREFVKWGPAEEGDIRDRARLDEVLAKHKPAAILHFAALIE
VGESVKDPVSFYENNVIGTLTLLSAAQAAGINAFVFSSTCATYGLPQSVPLDETHRQVPINPYGRTKYIVEQALADYDQY
RSLRSVVLRYFNAAGADFEGRIGEWHQPETHAIPLAIDAALGRRQGFKVFGSDYETRDGTCVRDYIHVLDLADAHVRAVE
YLLKGGESVALNLGTGTGTTVKELLGAIEDVSNRPFPVEYIGRREGDSHTLVANNDKARDVLGWVPQYDLSQIIRSAWDW
HAKSNQH

Sequences:

>Translated_327_residues
MAGETVLVVGGAGYIGSHTCLDLANKGYKPVVFDNFSNGHREFVKWGPAEEGDIRDRARLDEVLAKHKPAAILHFAALIE
VGESVKDPVSFYENNVIGTLTLLSAAQAAGINAFVFSSTCATYGLPQSVPLDETHRQVPINPYGRTKYIVEQALADYDQY
RSLRSVVLRYFNAAGADFEGRIGEWHQPETHAIPLAIDAALGRRQGFKVFGSDYETRDGTCVRDYIHVLDLADAHVRAVE
YLLKGGESVALNLGTGTGTTVKELLGAIEDVSNRPFPVEYIGRREGDSHTLVANNDKARDVLGWVPQYDLSQIIRSAWDW
HAKSNQH
>Mature_326_residues
AGETVLVVGGAGYIGSHTCLDLANKGYKPVVFDNFSNGHREFVKWGPAEEGDIRDRARLDEVLAKHKPAAILHFAALIEV
GESVKDPVSFYENNVIGTLTLLSAAQAAGINAFVFSSTCATYGLPQSVPLDETHRQVPINPYGRTKYIVEQALADYDQYR
SLRSVVLRYFNAAGADFEGRIGEWHQPETHAIPLAIDAALGRRQGFKVFGSDYETRDGTCVRDYIHVLDLADAHVRAVEY
LLKGGESVALNLGTGTGTTVKELLGAIEDVSNRPFPVEYIGRREGDSHTLVANNDKARDVLGWVPQYDLSQIIRSAWDWH
AKSNQH

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=344, Percent_Identity=40.9883720930233, Blast_Score=251, Evalue=7e-67,
Organism=Homo sapiens, GI56118217, Length=344, Percent_Identity=40.9883720930233, Blast_Score=251, Evalue=7e-67,
Organism=Homo sapiens, GI189083684, Length=344, Percent_Identity=40.9883720930233, Blast_Score=251, Evalue=7e-67,
Organism=Homo sapiens, GI7657641, Length=344, Percent_Identity=26.1627906976744, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI42516563, Length=324, Percent_Identity=24.6913580246914, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1786974, Length=332, Percent_Identity=39.7590361445783, Blast_Score=234, Evalue=6e-63,
Organism=Escherichia coli, GI1788353, Length=357, Percent_Identity=27.1708683473389, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI48994969, Length=342, Percent_Identity=27.7777777777778, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1790049, Length=304, Percent_Identity=26.3157894736842, Blast_Score=71, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71982035, Length=343, Percent_Identity=37.0262390670554, Blast_Score=216, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI71982038, Length=345, Percent_Identity=36.5217391304348, Blast_Score=216, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17568069, Length=347, Percent_Identity=25.3602305475504, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=342, Percent_Identity=39.1812865497076, Blast_Score=231, Evalue=2e-61,
Organism=Drosophila melanogaster, GI19923002, Length=343, Percent_Identity=39.067055393586, Blast_Score=229, Evalue=2e-60,
Organism=Drosophila melanogaster, GI21356223, Length=318, Percent_Identity=25.4716981132075, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35970; Mature: 35838

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGETVLVVGGAGYIGSHTCLDLANKGYKPVVFDNFSNGHREFVKWGPAEEGDIRDRARL
CCCCEEEEEECCCCCCCHHHHHHHCCCCCCEEECCCCCCHHHHHHCCCCCCCCCHHHHHH
DEVLAKHKPAAILHFAALIEVGESVKDPVSFYENNVIGTLTLLSAAQAAGINAFVFSSTC
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECHH
ATYGLPQSVPLDETHRQVPINPYGRTKYIVEQALADYDQYRSLRSVVLRYFNAAGADFEG
HHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
RIGEWHQPETHAIPLAIDAALGRRQGFKVFGSDYETRDGTCVRDYIHVLDLADAHVRAVE
CCCCCCCCCCCEEEEEEHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
YLLKGGESVALNLGTGTGTTVKELLGAIEDVSNRPFPVEYIGRREGDSHTLVANNDKARD
HHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCEEEECCCCHHH
VLGWVPQYDLSQIIRSAWDWHAKSNQH
HHHCCCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AGETVLVVGGAGYIGSHTCLDLANKGYKPVVFDNFSNGHREFVKWGPAEEGDIRDRARL
CCCEEEEEECCCCCCCHHHHHHHCCCCCCEEECCCCCCHHHHHHCCCCCCCCCHHHHHH
DEVLAKHKPAAILHFAALIEVGESVKDPVSFYENNVIGTLTLLSAAQAAGINAFVFSSTC
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECHH
ATYGLPQSVPLDETHRQVPINPYGRTKYIVEQALADYDQYRSLRSVVLRYFNAAGADFEG
HHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
RIGEWHQPETHAIPLAIDAALGRRQGFKVFGSDYETRDGTCVRDYIHVLDLADAHVRAVE
CCCCCCCCCCCEEEEEEHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
YLLKGGESVALNLGTGTGTTVKELLGAIEDVSNRPFPVEYIGRREGDSHTLVANNDKARD
HHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCEEEECCCCHHH
VLGWVPQYDLSQIIRSAWDWHAKSNQH
HHHCCCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9236769 [H]