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The map label for this gene is glpR [H]

Identifier: 209551404

GI number: 209551404

Start: 3965894

End: 3966670

Strand: Reverse

Name: glpR [H]

Synonym: Rleg2_3833

Alternate gene names: 209551404

Gene position: 3966670-3965894 (Counterclockwise)

Preceding gene: 209551409

Following gene: 209551403

Centisome position: 87.41

GC content: 62.29

Gene sequence:

>777_bases
ATGCAGGATTTTTTGTTGCGCGAGCGCCAGGGCGTGATTTCCGACAGGCTGCGGCTGAATGGCCGCGTTCTGGCGACGGA
ACTTGCGCTCGAATTCGGCGTCTCCGAAGATACGGTGCGGCGCGATCTGCGCGAAATGGCCGCGGCAGGGCTCTGCGAGC
GGGTCTATGGCGGCGCATTGCCGATCTCGCCGGCGCATGGAAGTCTGACGCAGCGGATCGGTTTTGCCGTTGACCGGAAA
CAGGCGCTGGCGCGCGCTGCAACACAGCAGATTGCCGCCGGTTCGACCGTATTCTTCGATGCCGGCAGCACCAATCTGGC
GATTGCCAATGCACTGCCGGATGAACTTGCGCTGACGGCTGCGACGAATGCGCCGGCGATCGCCGCAGCGCTGATCGACA
AGCCGTCCGTCAACGTCATCCTGATCGGCGGAATGGTGGACCGGCAGACGGGCGGCTCGCTCGGTGCCAAAGCCTTGCGG
GATATGGAGCAGATTTCGCCCGATCTTTGCATTCTCGGCGCCTGCGGCGTCGATCTTGAGGCCGGCATCACCGTATTCGG
TTTCGAAGATGCCGAGTTCAAGCGCTATGCGGCGTCGCGAAGCAAAAAGGTATTGGTGGCGGCAACCTCGGAGAAATTCG
GCACTGCAGCCCCCTATAGCATTCTGCCGGTTGCCCATTGCGAATGCCTGGTCGTCGAGCACGATGCGGATCCGGCCATT
CTCGCCGATTACCGCGCGCGCGGATGCAGGACTGTCGTCGCCGAGAAAACGAACTGA

Upstream 100 bases:

>100_bases
TTTCACAACGTCAGGAAATGTGTGTTTGTGCATATTGTGCGCCGGGTCTTAAGCGTTTATGCACGTTTCTAGTTTCAAAG
GTTTTCAATCCGGTAAAAAC

Downstream 100 bases:

>100_bases
GACTCTCGTCATCGAGTTTAGGGAAGCCGGGCGTGCAAGCCCGGCAATGAGGAAAGACCGAGAAATGGATAGTCATGTGA
ATGCGCCGCCGTCAGCTCGA

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MQDFLLRERQGVISDRLRLNGRVLATELALEFGVSEDTVRRDLREMAAAGLCERVYGGALPISPAHGSLTQRIGFAVDRK
QALARAATQQIAAGSTVFFDAGSTNLAIANALPDELALTAATNAPAIAAALIDKPSVNVILIGGMVDRQTGGSLGAKALR
DMEQISPDLCILGACGVDLEAGITVFGFEDAEFKRYAASRSKKVLVAATSEKFGTAAPYSILPVAHCECLVVEHDADPAI
LADYRARGCRTVVAEKTN

Sequences:

>Translated_258_residues
MQDFLLRERQGVISDRLRLNGRVLATELALEFGVSEDTVRRDLREMAAAGLCERVYGGALPISPAHGSLTQRIGFAVDRK
QALARAATQQIAAGSTVFFDAGSTNLAIANALPDELALTAATNAPAIAAALIDKPSVNVILIGGMVDRQTGGSLGAKALR
DMEQISPDLCILGACGVDLEAGITVFGFEDAEFKRYAASRSKKVLVAATSEKFGTAAPYSILPVAHCECLVVEHDADPAI
LADYRARGCRTVVAEKTN
>Mature_258_residues
MQDFLLRERQGVISDRLRLNGRVLATELALEFGVSEDTVRRDLREMAAAGLCERVYGGALPISPAHGSLTQRIGFAVDRK
QALARAATQQIAAGSTVFFDAGSTNLAIANALPDELALTAATNAPAIAAALIDKPSVNVILIGGMVDRQTGGSLGAKALR
DMEQISPDLCILGACGVDLEAGITVFGFEDAEFKRYAASRSKKVLVAATSEKFGTAAPYSILPVAHCECLVVEHDADPAI
LADYRARGCRTVVAEKTN

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=234, Percent_Identity=31.6239316239316, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1789519, Length=240, Percent_Identity=28.75, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1789059, Length=254, Percent_Identity=27.5590551181102, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787063, Length=214, Percent_Identity=27.5700934579439, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI226510968, Length=228, Percent_Identity=28.9473684210526, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI87082344, Length=208, Percent_Identity=27.4038461538462, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789170, Length=215, Percent_Identity=28.3720930232558, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787540, Length=220, Percent_Identity=27.7272727272727, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788069, Length=231, Percent_Identity=25.1082251082251, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1790753, Length=247, Percent_Identity=27.5303643724696, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27230; Mature: 27230

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDFLLRERQGVISDRLRLNGRVLATELALEFGVSEDTVRRDLREMAAAGLCERVYGGAL
CCCHHHHHHCCHHHHHHHCCCEEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
PISPAHGSLTQRIGFAVDRKQALARAATQQIAAGSTVFFDAGSTNLAIANALPDELALTA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEECCCCCHHEEEE
ATNAPAIAAALIDKPSVNVILIGGMVDRQTGGSLGAKALRDMEQISPDLCILGACGVDLE
CCCCCHHHHHHHCCCCCCEEEECCEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCHH
AGITVFGFEDAEFKRYAASRSKKVLVAATSEKFGTAAPYSILPVAHCECLVVEHDADPAI
CCEEEEECCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEECCEEEEEEECCCCCCE
LADYRARGCRTVVAEKTN
EHHHHCCCCEEEEEECCC
>Mature Secondary Structure
MQDFLLRERQGVISDRLRLNGRVLATELALEFGVSEDTVRRDLREMAAAGLCERVYGGAL
CCCHHHHHHCCHHHHHHHCCCEEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
PISPAHGSLTQRIGFAVDRKQALARAATQQIAAGSTVFFDAGSTNLAIANALPDELALTA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEECCCCCHHEEEE
ATNAPAIAAALIDKPSVNVILIGGMVDRQTGGSLGAKALRDMEQISPDLCILGACGVDLE
CCCCCHHHHHHHCCCCCCEEEECCEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCHH
AGITVFGFEDAEFKRYAASRSKKVLVAATSEKFGTAAPYSILPVAHCECLVVEHDADPAI
CCEEEEECCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEECCEEEEEEECCCCCCE
LADYRARGCRTVVAEKTN
EHHHHCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8955387; 3045764; 9278503 [H]