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The map label for this gene is hfaC [H]

Identifier: 209551379

GI number: 209551379

Start: 3940280

End: 3942100

Strand: Reverse

Name: hfaC [H]

Synonym: Rleg2_3808

Alternate gene names: 209551379

Gene position: 3942100-3940280 (Counterclockwise)

Preceding gene: 209551380

Following gene: 209551378

Centisome position: 86.87

GC content: 63.54

Gene sequence:

>1821_bases
TTGGCCCCTCCCATTCTGAAACTCGACGATATCTTTCTGAGCTTCGGCGGCGCGCCGCTTCTGGCTGGTGCCAGCCTGCA
GATCGAGCCCGGTGACAAAATCTGTCTCGTCGGGCGCAACGGCTCGGGAAAATCGACGCTTCTGAAGATCGCCGCCGGCC
TGGTCGAGGCGCAATCCGGCGAGGTCTTCCGTCATCCGTCCTCGACGGTGCGTTATCTCGAACAGGCGCCCGATTTTGCT
GGTTTCAACACTGTTCAGGCCTATGCCGAGGCCGGCCTCGGGCCGGGCGACGACCCGTATCGCGTCACCTATCTGCTGTC
CCATCTCGGGCTGACGGGCGAGGAAGATCCGAGCACCCTTTCCGGCGGCGAATCGCGCCGCGCAGCACTTGCCCGCGTGC
TGGCGCCGGAGCCCGACATTCTCCTGCTCGACGAGCCGACCAACCATCTCGACCTTCCCACAATCGAATGGCTGGAAGGC
GAGCTGCAGAAGACGCGCAGCGCCCTGGTGCTGATCTCGCACGACCGGCGCTTCCTGGAAAAGGTGTCGACGGCAACCGT
CTGGCTCGACCGCGGCACCTCGCGCCGGCTCGACAGGGGATTTTCGCATTTCGAGGCCTGGCGCGACCAGGTGCTCGAGG
CCGAAGAACTGGAGCAGCACAAACTCGGCAAGGCGATCGAGCGCGAGGAGCACTGGCTGCGTTACGGCGTCACGGCGCGG
CGCAAGCGCAACATGCGCCGTCTCGGCGAGTTGCAGACGATGCGCTCGCAATATCGCGGCCACAAGGGGCCGCAGGGCAC
GGTGCAGGCGACGGCTTCGGACGCGCAGGAATCCGGAAAGCTGGTGATCGAGGCCGACAAGATCACCAAGAGCTTCGGCG
ACCGGCCGATCGTCACGCCCTTCTCGATCCGCGTGCATCGCGGCGATTGCATCGGTCTGGTCGGGCCGAACGGCGCCGGC
AAGACGACGCTGCTGAAGATGCTGACCGGGCAGCTTTTACCGGATAGCGGCACGATAAAGCTCGGCACCAATCTGGAGAT
CGCGACGCTCGACCAGAAGCGCGAGGATCTCGATCCCGAAGATACGCTCGCCAATTACCTGACGGACGGGCGCGGCGAAA
ACCTGCTCGTCAACGGCGAGCAGCGTCATGTCACCGGCTATATGAAGGAGTTCCTGTTCCAGCCGGAGCAGGCACGAACG
CCGATCAGAAGCCTCTCCGGCGGCGAGCGCGCGAGGCTGATGCTGGCGCGTATTCTCTCGCGCCCGGCGAACCTCTTGAT
CCTCGACGAACCGACCAACGATCTCGATATCGAAACACTCGATTTGCTGCAGGAGATCGTCGCCGGTTTTCCCGGCACCG
TCATTCTCGTCAGCCACGACCGCGATTTCCTCGACCGCACCGTGACCTCGACGATTGCACCCGCCGTGCCGGACGCGCCT
GATGGCCGCTGGATCGAATATGCCGGCGGCTATTCCGACATGCTTGCGCAGCGCAAAGGCGCGATCGACGAGCGCAAGCG
GGCCGAGAAGGCTGCGGAGAAGCTGAAGATCCAGGAGGCGGCACCTTCCGGCGGAGGCTCGAAGAGCAAGCTCTCCTTCA
AGCAGAAATTCGCGTTGGACAATTTGCCGAAGGAGATGGCGAAAGCCGAAGCGGAGATCGCCAAACGCGAACAGGCGATG
GCTGATCCCAACCTTTTTACGCGCGATGCGGCTGCCTTCAACCGGCTTGCCAGCGAGATGGAGAAGCTGCGGGCCAGCCT
CACCAAGATGGAAGAGGAGTGGCTGGAGCTCGAAATGCTGCGGGAAGAGCTGGAAGGCTGA

Upstream 100 bases:

>100_bases
CACCATTTCCAATGTCGCGGAAGGCACGGTTCGCTTTTCGCTTCGCAGCGGCCGGGCGATTGTGCTCGCCAGGCCCTATG
ATCTTTCCGGAGTCTGATTT

Downstream 100 bases:

>100_bases
GGCTTTCCAACACTACCCGCCTCACCTTTCCTTGATTGGCCAGTCTGCCGTTGCACGGCATAAGGTGCCGTCCGGCAGAA
AATCCAAGTGTTGCAGCCTC

Product: ABC transporter

Products: NA

Alternate protein names: Protein HfaC [H]

Number of amino acids: Translated: 606; Mature: 605

Protein sequence:

>606_residues
MAPPILKLDDIFLSFGGAPLLAGASLQIEPGDKICLVGRNGSGKSTLLKIAAGLVEAQSGEVFRHPSSTVRYLEQAPDFA
GFNTVQAYAEAGLGPGDDPYRVTYLLSHLGLTGEEDPSTLSGGESRRAALARVLAPEPDILLLDEPTNHLDLPTIEWLEG
ELQKTRSALVLISHDRRFLEKVSTATVWLDRGTSRRLDRGFSHFEAWRDQVLEAEELEQHKLGKAIEREEHWLRYGVTAR
RKRNMRRLGELQTMRSQYRGHKGPQGTVQATASDAQESGKLVIEADKITKSFGDRPIVTPFSIRVHRGDCIGLVGPNGAG
KTTLLKMLTGQLLPDSGTIKLGTNLEIATLDQKREDLDPEDTLANYLTDGRGENLLVNGEQRHVTGYMKEFLFQPEQART
PIRSLSGGERARLMLARILSRPANLLILDEPTNDLDIETLDLLQEIVAGFPGTVILVSHDRDFLDRTVTSTIAPAVPDAP
DGRWIEYAGGYSDMLAQRKGAIDERKRAEKAAEKLKIQEAAPSGGGSKSKLSFKQKFALDNLPKEMAKAEAEIAKREQAM
ADPNLFTRDAAAFNRLASEMEKLRASLTKMEEEWLELEMLREELEG

Sequences:

>Translated_606_residues
MAPPILKLDDIFLSFGGAPLLAGASLQIEPGDKICLVGRNGSGKSTLLKIAAGLVEAQSGEVFRHPSSTVRYLEQAPDFA
GFNTVQAYAEAGLGPGDDPYRVTYLLSHLGLTGEEDPSTLSGGESRRAALARVLAPEPDILLLDEPTNHLDLPTIEWLEG
ELQKTRSALVLISHDRRFLEKVSTATVWLDRGTSRRLDRGFSHFEAWRDQVLEAEELEQHKLGKAIEREEHWLRYGVTAR
RKRNMRRLGELQTMRSQYRGHKGPQGTVQATASDAQESGKLVIEADKITKSFGDRPIVTPFSIRVHRGDCIGLVGPNGAG
KTTLLKMLTGQLLPDSGTIKLGTNLEIATLDQKREDLDPEDTLANYLTDGRGENLLVNGEQRHVTGYMKEFLFQPEQART
PIRSLSGGERARLMLARILSRPANLLILDEPTNDLDIETLDLLQEIVAGFPGTVILVSHDRDFLDRTVTSTIAPAVPDAP
DGRWIEYAGGYSDMLAQRKGAIDERKRAEKAAEKLKIQEAAPSGGGSKSKLSFKQKFALDNLPKEMAKAEAEIAKREQAM
ADPNLFTRDAAAFNRLASEMEKLRASLTKMEEEWLELEMLREELEG
>Mature_605_residues
APPILKLDDIFLSFGGAPLLAGASLQIEPGDKICLVGRNGSGKSTLLKIAAGLVEAQSGEVFRHPSSTVRYLEQAPDFAG
FNTVQAYAEAGLGPGDDPYRVTYLLSHLGLTGEEDPSTLSGGESRRAALARVLAPEPDILLLDEPTNHLDLPTIEWLEGE
LQKTRSALVLISHDRRFLEKVSTATVWLDRGTSRRLDRGFSHFEAWRDQVLEAEELEQHKLGKAIEREEHWLRYGVTARR
KRNMRRLGELQTMRSQYRGHKGPQGTVQATASDAQESGKLVIEADKITKSFGDRPIVTPFSIRVHRGDCIGLVGPNGAGK
TTLLKMLTGQLLPDSGTIKLGTNLEIATLDQKREDLDPEDTLANYLTDGRGENLLVNGEQRHVTGYMKEFLFQPEQARTP
IRSLSGGERARLMLARILSRPANLLILDEPTNDLDIETLDLLQEIVAGFPGTVILVSHDRDFLDRTVTSTIAPAVPDAPD
GRWIEYAGGYSDMLAQRKGAIDERKRAEKAAEKLKIQEAAPSGGGSKSKLSFKQKFALDNLPKEMAKAEAEIAKREQAMA
DPNLFTRDAAAFNRLASEMEKLRASLTKMEEEWLELEMLREELEG

Specific function: Involved in attachment of the holdfast to the cell. The holdfast is a structure that allows the bacteria to firmly adhere to surfaces [H]

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=520, Percent_Identity=31.1538461538462, Blast_Score=172, Evalue=9e-43,
Organism=Homo sapiens, GI10947135, Length=511, Percent_Identity=30.7240704500978, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI69354671, Length=511, Percent_Identity=30.7240704500978, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI10947137, Length=493, Percent_Identity=30.6288032454361, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI27881506, Length=493, Percent_Identity=30.6288032454361, Blast_Score=142, Evalue=1e-33,
Organism=Escherichia coli, GI1787182, Length=636, Percent_Identity=38.2075471698113, Blast_Score=393, Evalue=1e-110,
Organism=Escherichia coli, GI2367384, Length=355, Percent_Identity=38.5915492957746, Blast_Score=248, Evalue=1e-66,
Organism=Escherichia coli, GI1787041, Length=535, Percent_Identity=29.1588785046729, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1789751, Length=625, Percent_Identity=29.12, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1790190, Length=528, Percent_Identity=24.4318181818182, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1788225, Length=221, Percent_Identity=28.5067873303167, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788761, Length=230, Percent_Identity=31.304347826087, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1788165, Length=192, Percent_Identity=34.375, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI48994943, Length=481, Percent_Identity=25.1559251559252, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1787029, Length=213, Percent_Identity=28.6384976525822, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1786563, Length=212, Percent_Identity=30.6603773584906, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87081791, Length=198, Percent_Identity=30.3030303030303, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1787712, Length=191, Percent_Identity=29.8429319371728, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1786253, Length=215, Percent_Identity=31.1627906976744, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI87081834, Length=190, Percent_Identity=31.5789473684211, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1788450, Length=207, Percent_Identity=30.9178743961353, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786319, Length=179, Percent_Identity=33.5195530726257, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87081782, Length=203, Percent_Identity=32.0197044334975, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787370, Length=193, Percent_Identity=27.4611398963731, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI145693107, Length=232, Percent_Identity=28.8793103448276, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1790739, Length=199, Percent_Identity=30.1507537688442, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI87081709, Length=208, Percent_Identity=27.8846153846154, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789873, Length=202, Percent_Identity=27.7227722772277, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1786398, Length=197, Percent_Identity=28.4263959390863, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1787758, Length=231, Percent_Identity=27.2727272727273, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1787105, Length=202, Percent_Identity=31.1881188118812, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788210, Length=234, Percent_Identity=27.7777777777778, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI48995001, Length=186, Percent_Identity=32.7956989247312, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786803, Length=169, Percent_Identity=32.5443786982249, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI48994997, Length=175, Percent_Identity=31.4285714285714, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=571, Percent_Identity=27.1453590192644, Blast_Score=158, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17555318, Length=496, Percent_Identity=28.4274193548387, Blast_Score=155, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI17553372, Length=515, Percent_Identity=30.873786407767, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17555800, Length=503, Percent_Identity=23.6580516898608, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI115533608, Length=200, Percent_Identity=29.5, Blast_Score=69, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6320874, Length=536, Percent_Identity=27.0522388059701, Blast_Score=160, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6321121, Length=384, Percent_Identity=28.3854166666667, Blast_Score=124, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6324314, Length=346, Percent_Identity=29.7687861271676, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6323278, Length=346, Percent_Identity=29.4797687861272, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6325030, Length=201, Percent_Identity=30.8457711442786, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24642252, Length=557, Percent_Identity=28.3662477558348, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI18859989, Length=557, Percent_Identity=28.3662477558348, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24641342, Length=521, Percent_Identity=29.5585412667946, Blast_Score=173, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24666836, Length=506, Percent_Identity=30.2371541501976, Blast_Score=164, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR007406 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 66946; Mature: 66815

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPPILKLDDIFLSFGGAPLLAGASLQIEPGDKICLVGRNGSGKSTLLKIAAGLVEAQSG
CCCCCCCHHHHHHHCCCCCEEECCEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHCCCC
EVFRHPSSTVRYLEQAPDFAGFNTVQAYAEAGLGPGDDPYRVTYLLSHLGLTGEEDPSTL
CEEECCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
SGGESRRAALARVLAPEPDILLLDEPTNHLDLPTIEWLEGELQKTRSALVLISHDRRFLE
CCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEEECCHHHHH
KVSTATVWLDRGTSRRLDRGFSHFEAWRDQVLEAEELEQHKLGKAIEREEHWLRYGVTAR
HHHHHEEEEECCCHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHH
RKRNMRRLGELQTMRSQYRGHKGPQGTVQATASDAQESGKLVIEADKITKSFGDRPIVTP
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHHCCCEEEEHHHHHHHHCCCCCCCC
FSIRVHRGDCIGLVGPNGAGKTTLLKMLTGQLLPDSGTIKLGTNLEIATLDQKREDLDPE
EEEEEECCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEECCCEEEEECCCHHHCCCHH
DTLANYLTDGRGENLLVNGEQRHVTGYMKEFLFQPEQARTPIRSLSGGERARLMLARILS
HHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCHHHCCCHHHCCCCHHHHHHHHHHHC
RPANLLILDEPTNDLDIETLDLLQEIVAGFPGTVILVSHDRDFLDRTVTSTIAPAVPDAP
CCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCC
DGRWIEYAGGYSDMLAQRKGAIDERKRAEKAAEKLKIQEAAPSGGGSKSKLSFKQKFALD
CCCEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
NLPKEMAKAEAEIAKREQAMADPNLFTRDAAAFNRLASEMEKLRASLTKMEEEWLELEML
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REELEG
HHHHCC
>Mature Secondary Structure 
APPILKLDDIFLSFGGAPLLAGASLQIEPGDKICLVGRNGSGKSTLLKIAAGLVEAQSG
CCCCCCHHHHHHHCCCCCEEECCEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHCCCC
EVFRHPSSTVRYLEQAPDFAGFNTVQAYAEAGLGPGDDPYRVTYLLSHLGLTGEEDPSTL
CEEECCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
SGGESRRAALARVLAPEPDILLLDEPTNHLDLPTIEWLEGELQKTRSALVLISHDRRFLE
CCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEEECCHHHHH
KVSTATVWLDRGTSRRLDRGFSHFEAWRDQVLEAEELEQHKLGKAIEREEHWLRYGVTAR
HHHHHEEEEECCCHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHH
RKRNMRRLGELQTMRSQYRGHKGPQGTVQATASDAQESGKLVIEADKITKSFGDRPIVTP
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHHCCCEEEEHHHHHHHHCCCCCCCC
FSIRVHRGDCIGLVGPNGAGKTTLLKMLTGQLLPDSGTIKLGTNLEIATLDQKREDLDPE
EEEEEECCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEECCCEEEEECCCHHHCCCHH
DTLANYLTDGRGENLLVNGEQRHVTGYMKEFLFQPEQARTPIRSLSGGERARLMLARILS
HHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCHHHCCCHHHCCCCHHHHHHHHHHHC
RPANLLILDEPTNDLDIETLDLLQEIVAGFPGTVILVSHDRDFLDRTVTSTIAPAVPDAP
CCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCC
DGRWIEYAGGYSDMLAQRKGAIDERKRAEKAAEKLKIQEAAPSGGGSKSKLSFKQKFALD
CCCEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
NLPKEMAKAEAEIAKREQAMADPNLFTRDAAAFNRLASEMEKLRASLTKMEEEWLELEML
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REELEG
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11259647; 8150261 [H]