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The map label for this gene is yleA [C]

Identifier: 209551318

GI number: 209551318

Start: 3873088

End: 3874362

Strand: Reverse

Name: yleA [C]

Synonym: Rleg2_3747

Alternate gene names: 209551318

Gene position: 3874362-3873088 (Counterclockwise)

Preceding gene: 209551319

Following gene: 209551317

Centisome position: 85.38

GC content: 64.24

Gene sequence:

>1275_bases
GTGAGCGGCGTCGACGTCATTACCTTCGGCTGCCGCCTCAACACCTATGAATCCGAAGTGATGAAGGCGCAGGCCGAGAA
GGCCGGGCTCAACAATGCCATCCTGATCAACACCTGTGCGGTGACCGGCGAGGCCGTGCGTCAGGCGCGCCAGGCGATCC
GTCGGGCACGCCGCGACAATCCGCATGCCCGCATCATCGTCACCGGCTGCGCCGCACAGACGGAAAAGGAAACCTTCGCT
GAAATGGCGGAGGTCGATGCCGTGCTCGGCAACGAGGAGAAGCTTGCGAGCGCCTCCTATCGCAGCCTGCCGGATTTCGG
CGTTTCGACTGAGGAGAAGCTCCGCGTCAACGATATCATGAGCGTCAAGGCGACGGCGCCGCAGATGGTCAGGCATATCG
ACGGGCATGTGCGCGCCTTCATCCAGGTGCAGAACGGCTGCGACCATCGCTGCACCTTCTGCATCATCCCCTATGGCCGC
GGCAATTCCCGCTCGGTGCCGATGGGCGCGGTCGTCGACCAGGCCCGCAAGCTCGCCGACAGCGGCTACCGCGAAATCGT
GCTGACCGGGGTCGACGCCACAAGTTATGGCGGCGACCTGCCGGGTGCGCCGACGCTCGGGCTTCTGGCGAAGACGCTGT
TGAAGCAGCTCCCCGATATCAGCCGCCTCAGGCTTTCCTCGATCGACAGTATCGAGGCCGATGCCCATCTGATGGATCTC
ATCGCCGACGAGCCGCGTTTCATGCCGCATCTGCATCTGTCGCTGCAGCATGGCGACGACATGATCCTGAAGCGGATGAA
GCGCCGGCATTCCCGCGCCGATGCGCTGCGTTTCATCGAGGACGTACGCCGGCTTCGCCCCGAGATGAGCTTCGGCGCCG
ATATGATCGCCGGCTTCCCGACGGAGACGGAAGAGATGTTCGGCAATGCGGTGCGGCTTGCCGAAGAGGCCGGCATCGCA
CATCTGCATGTCTTTCCCTACAGCCCGCGTCCGGGCACGCCGGCCGCCCGCATGCCGCAGCTCGACCGGTCTCTGGTCAA
GGATCGCGCTGCCAGGCTGCGCGCCACTGGACACAGGCTGCATCAGTCCCATCTCGACGGCATGGTCGGAACCCGGCAAT
GGCTGCTTGTCGAAAACAACGGCCTGGCGCATACGGAAAACTTCGCGCTGGTGGCAGCACCCGGCCTTCGTCCCGGTGAA
CTTGTGCCGGCCACGATCACCGGCCACAATGGCAAACATCTTGACATGCAATTGACGGCCGCAGCCGCGGCCTGA

Upstream 100 bases:

>100_bases
ACGTGATCATGACCGGCCCGGCCGAATGGGAATGGTCGGGCAGTCTCGATCCCTCGACTGGCCTCTGGTCGCGCGACGGT
ACCCAAGAGGCGGGGGCGCG

Downstream 100 bases:

>100_bases
CTTTCACGGAATCCCCATGGCGCTCAGTTTCATCAAAAAGGTCTTCACCTTCGGCAAGGACAAGCCGGCGGAAGAGCCCG
TGCCTGAAGCCGTGGCAAGG

Product: MiaB-like tRNA modifying protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MSGVDVITFGCRLNTYESEVMKAQAEKAGLNNAILINTCAVTGEAVRQARQAIRRARRDNPHARIIVTGCAAQTEKETFA
EMAEVDAVLGNEEKLASASYRSLPDFGVSTEEKLRVNDIMSVKATAPQMVRHIDGHVRAFIQVQNGCDHRCTFCIIPYGR
GNSRSVPMGAVVDQARKLADSGYREIVLTGVDATSYGGDLPGAPTLGLLAKTLLKQLPDISRLRLSSIDSIEADAHLMDL
IADEPRFMPHLHLSLQHGDDMILKRMKRRHSRADALRFIEDVRRLRPEMSFGADMIAGFPTETEEMFGNAVRLAEEAGIA
HLHVFPYSPRPGTPAARMPQLDRSLVKDRAARLRATGHRLHQSHLDGMVGTRQWLLVENNGLAHTENFALVAAPGLRPGE
LVPATITGHNGKHLDMQLTAAAAA

Sequences:

>Translated_424_residues
MSGVDVITFGCRLNTYESEVMKAQAEKAGLNNAILINTCAVTGEAVRQARQAIRRARRDNPHARIIVTGCAAQTEKETFA
EMAEVDAVLGNEEKLASASYRSLPDFGVSTEEKLRVNDIMSVKATAPQMVRHIDGHVRAFIQVQNGCDHRCTFCIIPYGR
GNSRSVPMGAVVDQARKLADSGYREIVLTGVDATSYGGDLPGAPTLGLLAKTLLKQLPDISRLRLSSIDSIEADAHLMDL
IADEPRFMPHLHLSLQHGDDMILKRMKRRHSRADALRFIEDVRRLRPEMSFGADMIAGFPTETEEMFGNAVRLAEEAGIA
HLHVFPYSPRPGTPAARMPQLDRSLVKDRAARLRATGHRLHQSHLDGMVGTRQWLLVENNGLAHTENFALVAAPGLRPGE
LVPATITGHNGKHLDMQLTAAAAA
>Mature_423_residues
SGVDVITFGCRLNTYESEVMKAQAEKAGLNNAILINTCAVTGEAVRQARQAIRRARRDNPHARIIVTGCAAQTEKETFAE
MAEVDAVLGNEEKLASASYRSLPDFGVSTEEKLRVNDIMSVKATAPQMVRHIDGHVRAFIQVQNGCDHRCTFCIIPYGRG
NSRSVPMGAVVDQARKLADSGYREIVLTGVDATSYGGDLPGAPTLGLLAKTLLKQLPDISRLRLSSIDSIEADAHLMDLI
ADEPRFMPHLHLSLQHGDDMILKRMKRRHSRADALRFIEDVRRLRPEMSFGADMIAGFPTETEEMFGNAVRLAEEAGIAH
LHVFPYSPRPGTPAARMPQLDRSLVKDRAARLRATGHRLHQSHLDGMVGTRQWLLVENNGLAHTENFALVAAPGLRPGEL
VPATITGHNGKHLDMQLTAAAAA

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MTTase N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=434, Percent_Identity=28.5714285714286, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI28872782, Length=368, Percent_Identity=25.5434782608696, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI28872784, Length=368, Percent_Identity=25.5434782608696, Blast_Score=123, Evalue=3e-28,
Organism=Escherichia coli, GI1786882, Length=448, Percent_Identity=28.125, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1787057, Length=397, Percent_Identity=27.455919395466, Blast_Score=149, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI17553146, Length=478, Percent_Identity=28.0334728033473, Blast_Score=165, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI71996771, Length=330, Percent_Identity=27.5757575757576, Blast_Score=118, Evalue=5e-27,
Organism=Drosophila melanogaster, GI21356207, Length=425, Percent_Identity=27.2941176470588, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI19922432, Length=367, Percent_Identity=28.6103542234332, Blast_Score=142, Evalue=6e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 46408; Mature: 46277

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGVDVITFGCRLNTYESEVMKAQAEKAGLNNAILINTCAVTGEAVRQARQAIRRARRDN
CCCCEEEEEEEEECCHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCC
PHARIIVTGCAAQTEKETFAEMAEVDAVLGNEEKLASASYRSLPDFGVSTEEKLRVNDIM
CCEEEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHEEHHHHH
SVKATAPQMVRHIDGHVRAFIQVQNGCDHRCTFCIIPYGRGNSRSVPMGAVVDQARKLAD
HHHHHHHHHHHHHCCHHEEEEEECCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHH
SGYREIVLTGVDATSYGGDLPGAPTLGLLAKTLLKQLPDISRLRLSSIDSIEADAHLMDL
CCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHH
IADEPRFMPHLHLSLQHGDDMILKRMKRRHSRADALRFIEDVRRLRPEMSFGADMIAGFP
HHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHCCCC
TETEEMFGNAVRLAEEAGIAHLHVFPYSPRPGTPAARMPQLDRSLVKDRAARLRATGHRL
CCHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
HQSHLDGMVGTRQWLLVENNGLAHTENFALVAAPGLRPGELVPATITGHNGKHLDMQLTA
HHHHHCCCCCCCEEEEEECCCCCEECCEEEEECCCCCCCCEEEEEEECCCCCEEEEEEEE
AAAA
ECCC
>Mature Secondary Structure 
SGVDVITFGCRLNTYESEVMKAQAEKAGLNNAILINTCAVTGEAVRQARQAIRRARRDN
CCCEEEEEEEEECCHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCC
PHARIIVTGCAAQTEKETFAEMAEVDAVLGNEEKLASASYRSLPDFGVSTEEKLRVNDIM
CCEEEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHEEHHHHH
SVKATAPQMVRHIDGHVRAFIQVQNGCDHRCTFCIIPYGRGNSRSVPMGAVVDQARKLAD
HHHHHHHHHHHHHCCHHEEEEEECCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHH
SGYREIVLTGVDATSYGGDLPGAPTLGLLAKTLLKQLPDISRLRLSSIDSIEADAHLMDL
CCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHH
IADEPRFMPHLHLSLQHGDDMILKRMKRRHSRADALRFIEDVRRLRPEMSFGADMIAGFP
HHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHCCCC
TETEEMFGNAVRLAEEAGIAHLHVFPYSPRPGTPAARMPQLDRSLVKDRAARLRATGHRL
CCHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
HQSHLDGMVGTRQWLLVENNGLAHTENFALVAAPGLRPGELVPATITGHNGKHLDMQLTA
HHHHHCCCCCCCEEEEEECCCCCEECCEEEEECCCCCCCCEEEEEEECCCCCEEEEEEEE
AAAA
ECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]