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The map label for this gene is sdhB [H]

Identifier: 209551260

GI number: 209551260

Start: 3818801

End: 3819580

Strand: Reverse

Name: sdhB [H]

Synonym: Rleg2_3688

Alternate gene names: 209551260

Gene position: 3819580-3818801 (Counterclockwise)

Preceding gene: 209551261

Following gene: 209551259

Centisome position: 84.17

GC content: 61.03

Gene sequence:

>780_bases
ATGGTTGAACTCGCTCTTCCCAAAAACTCGCAGATGCGCGAAGGCAAGGTCTGGCCGAAGCCGGCGGGTGCGACGAACAC
CCGCGAATTCCGCGTCTACCGCTGGAGCCCGGATGACGGGCAGAACCCGTCGATCGATATCTTCTACATCGATGTCGACG
ATTGCGGCCCGATGGTGCTCGACGGCCTGCTCTATATCAAGAACAAGATCGACCCGACGCTGACGCTGCGCCGGTCCTGT
CGCGAGGGCATCTGCGGTTCCTGCGCGATGAATATCGACGGCACGAACACGCTCGCCTGCACCAAGGGTCTCGACGATAT
CACCGGCGCAGTGAAGATCTATCCGCTGCCGCATTTGCCCGTCGTCAAGGATCTGGTGCCGGATCTCACCAACTTCTACG
CCCAGCATCGTTCGATTGAGCCCTGGCTGAAGACGGTGTCGCCGGCGCCCGCCAAGGAATGGAAGCAGAGCCATGAGGAC
CGGCAGAAGCTCGACGGCCTTTACGAATGCATCCTCTGCGCCTGCTGCTCGACCTCCTGTCCGAGCTATTGGTGGAACGG
CGACCGCTATCTTGGTCCGGCCGTCCTGCTGCAGGCCTATCGCTGGCTGATCGATTCCAGAGACGAGGCAACCGGCGAAC
GTCTCGACAATCTTGAGGACCCGTTCCGCCTGTATCGCTGCCACACGATCATGAATTGCGCGCAGACCTGCCCGAAGGGC
CTCAACCCGGCCAAGGCAATCGCCGAGATCAAGAAGATGATGGTCGAGCGCCGGGTCTGA

Upstream 100 bases:

>100_bases
TTCTGGTGCAGTGGCCTTCGTTCGTGCCAGCAACGCTGCGTTCGGCGGTTGCAAGGGTTATGTGAAGACAGAATTCCTGT
CGGCAAACTAGGATCTTACT

Downstream 100 bases:

>100_bases
TCAACACATGCATGCCGATGGCGGAATAGACGGCTTCGATCCAGAAGCCGTTTCGCAGGTGAGGTCGGGCGGCGCGCGTT
GAAGCGGTATTCTCAGACAT

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MVELALPKNSQMREGKVWPKPAGATNTREFRVYRWSPDDGQNPSIDIFYIDVDDCGPMVLDGLLYIKNKIDPTLTLRRSC
REGICGSCAMNIDGTNTLACTKGLDDITGAVKIYPLPHLPVVKDLVPDLTNFYAQHRSIEPWLKTVSPAPAKEWKQSHED
RQKLDGLYECILCACCSTSCPSYWWNGDRYLGPAVLLQAYRWLIDSRDEATGERLDNLEDPFRLYRCHTIMNCAQTCPKG
LNPAKAIAEIKKMMVERRV

Sequences:

>Translated_259_residues
MVELALPKNSQMREGKVWPKPAGATNTREFRVYRWSPDDGQNPSIDIFYIDVDDCGPMVLDGLLYIKNKIDPTLTLRRSC
REGICGSCAMNIDGTNTLACTKGLDDITGAVKIYPLPHLPVVKDLVPDLTNFYAQHRSIEPWLKTVSPAPAKEWKQSHED
RQKLDGLYECILCACCSTSCPSYWWNGDRYLGPAVLLQAYRWLIDSRDEATGERLDNLEDPFRLYRCHTIMNCAQTCPKG
LNPAKAIAEIKKMMVERRV
>Mature_259_residues
MVELALPKNSQMREGKVWPKPAGATNTREFRVYRWSPDDGQNPSIDIFYIDVDDCGPMVLDGLLYIKNKIDPTLTLRRSC
REGICGSCAMNIDGTNTLACTKGLDDITGAVKIYPLPHLPVVKDLVPDLTNFYAQHRSIEPWLKTVSPAPAKEWKQSHED
RQKLDGLYECILCACCSTSCPSYWWNGDRYLGPAVLLQAYRWLIDSRDEATGERLDNLEDPFRLYRCHTIMNCAQTCPKG
LNPAKAIAEIKKMMVERRV

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=238, Percent_Identity=67.2268907563025, Blast_Score=343, Evalue=6e-95,
Organism=Escherichia coli, GI1786943, Length=234, Percent_Identity=52.5641025641026, Blast_Score=253, Evalue=6e-69,
Organism=Escherichia coli, GI1790596, Length=224, Percent_Identity=33.4821428571429, Blast_Score=128, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17533915, Length=232, Percent_Identity=61.2068965517241, Blast_Score=311, Evalue=3e-85,
Organism=Saccharomyces cerevisiae, GI6322987, Length=231, Percent_Identity=65.3679653679654, Blast_Score=313, Evalue=1e-86,
Organism=Drosophila melanogaster, GI17137106, Length=256, Percent_Identity=61.328125, Blast_Score=345, Evalue=2e-95,
Organism=Drosophila melanogaster, GI24643156, Length=232, Percent_Identity=62.0689655172414, Blast_Score=313, Evalue=6e-86,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 29373; Mature: 29373

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVELALPKNSQMREGKVWPKPAGATNTREFRVYRWSPDDGQNPSIDIFYIDVDDCGPMVL
CEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEEEECCCCCHHHH
DGLLYIKNKIDPTLTLRRSCREGICGSCAMNIDGTNTLACTKGLDDITGAVKIYPLPHLP
HHHHHHHHCCCHHHHHHHHHHCCCCCCEEECCCCCCCEEECCCCHHHCCCEEEEECCCCC
VVKDLVPDLTNFYAQHRSIEPWLKTVSPAPAKEWKQSHEDRQKLDGLYECILCACCSTSC
HHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PSYWWNGDRYLGPAVLLQAYRWLIDSRDEATGERLDNLEDPFRLYRCHTIMNCAQTCPKG
CCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
LNPAKAIAEIKKMMVERRV
CCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVELALPKNSQMREGKVWPKPAGATNTREFRVYRWSPDDGQNPSIDIFYIDVDDCGPMVL
CEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEEEECCCCCHHHH
DGLLYIKNKIDPTLTLRRSCREGICGSCAMNIDGTNTLACTKGLDDITGAVKIYPLPHLP
HHHHHHHHCCCHHHHHHHHHHCCCCCCEEECCCCCCCEEECCCCHHHCCCEEEEECCCCC
VVKDLVPDLTNFYAQHRSIEPWLKTVSPAPAKEWKQSHEDRQKLDGLYECILCACCSTSC
HHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PSYWWNGDRYLGPAVLLQAYRWLIDSRDEATGERLDNLEDPFRLYRCHTIMNCAQTCPKG
CCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
LNPAKAIAEIKKMMVERRV
CCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA