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The map label for this gene is xerC [H]

Identifier: 209551233

GI number: 209551233

Start: 3789929

End: 3790864

Strand: Direct

Name: xerC [H]

Synonym: Rleg2_3661

Alternate gene names: 209551233

Gene position: 3789929-3790864 (Clockwise)

Preceding gene: 209551230

Following gene: 209551234

Centisome position: 83.52

GC content: 66.56

Gene sequence:

>936_bases
GTGAACGAACTGCTTGTAATCGCCGATCCGCGCCTGATGGCGGAACGGGCCGCATGGCTCGAAAATCTCGCCCGAGAGCG
TCGTCTTTCCGAGCATACACTCGATGCCTATGAGCGCGACACCCGCCAGTTCCTGACCTTCCTGACCGGCCATCTCGCCG
GCCCGGCGACGCTCGGCGATATCAGGGAGCTGCGTCCCGCCGATTTCCGTGCCTTCCTGGCCGCCCGGCGCAAGCAAGGC
TCCGGCGCCCGCTCGCTCGGCCGCAATCTCGCCGGCCTTCGTTCGCTGCTGCGCTATCTCGAAAAGAAGGGCCTGGTCAA
TGCTGCCGGCGCGGGCGCGATCCGCTCGCCGAAACAGCCGAAATCGCTGCCGAAGCCGCTGTCGGACACGCAGGCGATCA
CCGTCGTCAGCAACGAGGCCCAGCTTCACGACGAACCTTGGATCGCCGCCCGCGATGCGGCTGTCATGACGCTGCTTTAC
GGCTGCGGCCTGCGCATCTCCGAAGCGCTGGATCTCATTCCCTCAGACCTGAAGAAGGGCGCCACAACGCTGCGCATTAC
CGGCAAGGGCAACAAGACACGGCTGGTACCGCTGCTGTCCGTGGTGTTCGACGCGGTCGAGAAATACCGCACGCTCTGCC
CCTACGATCTCGAGCCCGGCGAGCCGCTGTTTCGCGGCGCCCGCGGCGGCAAGCTGCAGGCGGCGATCATCCAGCGCGCC
ATGCAGAAGCTGCGCAGCGCCTTTGGCCTGCCGGAGACGGCAACGCCCCATGCGCTGCGCCATTCCTTCGCCACCCACCT
GCTTGCCGGCGGCGGCGATCTGCGCACCATCCAGGAGCTGCTCGGCCATGCCAGCCTGTCCACGACACAGGTCTATACCG
GCGTCGATGCGTCGCGGCTGCTTGAGGTGTATGATCGCGCTCATCCGCGCGCGTAG

Upstream 100 bases:

>100_bases
ATATGATCTAAGGATGACAAAGGCTTGGCGGGCATTAGCAATTCCATAACCGTTCCTGTTTCAAATTGGCGGACTTGAAG
GCAAATTCAAGGCCAGCGAC

Downstream 100 bases:

>100_bases
AGCCTTTTCCGGTCGGATCGAAACATTCTGCCGGAGCGAGAAAGACTCTAAGCTTTCGTTAACGCATTCTCTTAAAGGAT
TATGCGCAAGCCGGGCGTAG

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MNELLVIADPRLMAERAAWLENLARERRLSEHTLDAYERDTRQFLTFLTGHLAGPATLGDIRELRPADFRAFLAARRKQG
SGARSLGRNLAGLRSLLRYLEKKGLVNAAGAGAIRSPKQPKSLPKPLSDTQAITVVSNEAQLHDEPWIAARDAAVMTLLY
GCGLRISEALDLIPSDLKKGATTLRITGKGNKTRLVPLLSVVFDAVEKYRTLCPYDLEPGEPLFRGARGGKLQAAIIQRA
MQKLRSAFGLPETATPHALRHSFATHLLAGGGDLRTIQELLGHASLSTTQVYTGVDASRLLEVYDRAHPRA

Sequences:

>Translated_311_residues
MNELLVIADPRLMAERAAWLENLARERRLSEHTLDAYERDTRQFLTFLTGHLAGPATLGDIRELRPADFRAFLAARRKQG
SGARSLGRNLAGLRSLLRYLEKKGLVNAAGAGAIRSPKQPKSLPKPLSDTQAITVVSNEAQLHDEPWIAARDAAVMTLLY
GCGLRISEALDLIPSDLKKGATTLRITGKGNKTRLVPLLSVVFDAVEKYRTLCPYDLEPGEPLFRGARGGKLQAAIIQRA
MQKLRSAFGLPETATPHALRHSFATHLLAGGGDLRTIQELLGHASLSTTQVYTGVDASRLLEVYDRAHPRA
>Mature_311_residues
MNELLVIADPRLMAERAAWLENLARERRLSEHTLDAYERDTRQFLTFLTGHLAGPATLGDIRELRPADFRAFLAARRKQG
SGARSLGRNLAGLRSLLRYLEKKGLVNAAGAGAIRSPKQPKSLPKPLSDTQAITVVSNEAQLHDEPWIAARDAAVMTLLY
GCGLRISEALDLIPSDLKKGATTLRITGKGNKTRLVPLLSVVFDAVEKYRTLCPYDLEPGEPLFRGARGGKLQAAIIQRA
MQKLRSAFGLPETATPHALRHSFATHLLAGGGDLRTIQELLGHASLSTTQVYTGVDASRLLEVYDRAHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=312, Percent_Identity=37.8205128205128, Blast_Score=164, Evalue=9e-42,
Organism=Escherichia coli, GI1790244, Length=295, Percent_Identity=35.5932203389831, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI1790768, Length=161, Percent_Identity=31.055900621118, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34039; Mature: 34039

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNELLVIADPRLMAERAAWLENLARERRLSEHTLDAYERDTRQFLTFLTGHLAGPATLGD
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
IRELRPADFRAFLAARRKQGSGARSLGRNLAGLRSLLRYLEKKGLVNAAGAGAIRSPKQP
HHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
KSLPKPLSDTQAITVVSNEAQLHDEPWIAARDAAVMTLLYGCGLRISEALDLIPSDLKKG
CCCCCCCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
ATTLRITGKGNKTRLVPLLSVVFDAVEKYRTLCPYDLEPGEPLFRGARGGKLQAAIIQRA
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCHHHHHHHHH
MQKLRSAFGLPETATPHALRHSFATHLLAGGGDLRTIQELLGHASLSTTQVYTGVDASRL
HHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHCCCCCHHHH
LEVYDRAHPRA
HHHHHHCCCCC
>Mature Secondary Structure
MNELLVIADPRLMAERAAWLENLARERRLSEHTLDAYERDTRQFLTFLTGHLAGPATLGD
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
IRELRPADFRAFLAARRKQGSGARSLGRNLAGLRSLLRYLEKKGLVNAAGAGAIRSPKQP
HHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
KSLPKPLSDTQAITVVSNEAQLHDEPWIAARDAAVMTLLYGCGLRISEALDLIPSDLKKG
CCCCCCCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
ATTLRITGKGNKTRLVPLLSVVFDAVEKYRTLCPYDLEPGEPLFRGARGGKLQAAIIQRA
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCHHHHHHHHH
MQKLRSAFGLPETATPHALRHSFATHLLAGGGDLRTIQELLGHASLSTTQVYTGVDASRL
HHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHCCCCCHHHH
LEVYDRAHPRA
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]