| Definition | Rhizobium leguminosarum bv. trifolii WSM2304 chromosome, complete genome. |
|---|---|
| Accession | NC_011369 |
| Length | 4,537,948 |
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The map label for this gene is fabG [C]
Identifier: 209551215
GI number: 209551215
Start: 3772201
End: 3772971
Strand: Reverse
Name: fabG [C]
Synonym: Rleg2_3641
Alternate gene names: 209551215
Gene position: 3772971-3772201 (Counterclockwise)
Preceding gene: 209551216
Following gene: 209551214
Centisome position: 83.14
GC content: 62.65
Gene sequence:
>771_bases GTGTTTCATCCCAGACTGTTCGAAAATCGCAATGTCGTCGTCACCGGCGCCGGCCGCGGCATCGGCCTCGAAGTCGCTCG GCAGTTTCTGGATTGCGGCGCCAAGGTGATCGTCCATACCGGGCGCAAGCCGGGGCGGGACCTGCCGGATTTCCTGCTGA CGGCTGAATCCGAAAGACGGGCGCTGCTGTTGCATGCCGATTTCTCCGCCGCCGGCGGTGCGGCGCAATTTGCCGACGAT GTTCTCGCTTTCTTCGACAGGGTGCATGTGCTCGTCAACAATGCCGGCACCATGCTCGGCCGTTTTCCCGCTGCGACGCT GACCGATGCCGAATATGAGGCGGTCATACGGTTGAACCAGACCTCGGTGGTGGCGCTGACGCGCGCATTGCTGCCGGCAT TGAAGGCGGCCGAGGGTGCCGCCGTCGTCAACACCGTTTCGATCTCGGCGCTCACCGGCGGCAGCCCCGGCTCCTCGATC TATTCGGCCTCGAAAGCCTTCGTTGCGACCTATTCCAAGGCGCTTGCCCGCGAACTTGCCCCGGATGGCATCCGCGTCAA CTGCGTCTCGCCGGGAACGATCGAGACGGATTTTCACGAGCGCTACTCCTCCAGAGAAAAGCTGGAGCAGACCCGGAAAT CCATCCCCCTGCAGCGGCTCGGCACGGCCGAGGATTGTGCTCCCGCCTATCTGTTCCTGGCGGCTCCCTTACTCTCGGGA TACATTACCGGCCAGGTGATCGAGATCAATGGCGGACAGCTTATCTGCTGA
Upstream 100 bases:
>100_bases TTTAGCCCTGGCTTTCCCCGGAAAGATCGATGCCTGCCTTTCTTTCGGTCGGTGTGCTCATATGTTAAGGGCAAGTGACG CAACCGAGGAGGACGGCTTC
Downstream 100 bases:
>100_bases TTTACTTGGACCTTTTTTGGCATTTCATCACTATTGACCAATTCGTTTGTGCGAATATGCTATTGTGCTGATCTACCAAA TCGCCTCCCTTCCGAGATAT
Product: short-chain dehydrogenase/reductase SDR
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 256; Mature: 256
Protein sequence:
>256_residues MFHPRLFENRNVVVTGAGRGIGLEVARQFLDCGAKVIVHTGRKPGRDLPDFLLTAESERRALLLHADFSAAGGAAQFADD VLAFFDRVHVLVNNAGTMLGRFPAATLTDAEYEAVIRLNQTSVVALTRALLPALKAAEGAAVVNTVSISALTGGSPGSSI YSASKAFVATYSKALARELAPDGIRVNCVSPGTIETDFHERYSSREKLEQTRKSIPLQRLGTAEDCAPAYLFLAAPLLSG YITGQVIEINGGQLIC
Sequences:
>Translated_256_residues MFHPRLFENRNVVVTGAGRGIGLEVARQFLDCGAKVIVHTGRKPGRDLPDFLLTAESERRALLLHADFSAAGGAAQFADD VLAFFDRVHVLVNNAGTMLGRFPAATLTDAEYEAVIRLNQTSVVALTRALLPALKAAEGAAVVNTVSISALTGGSPGSSI YSASKAFVATYSKALARELAPDGIRVNCVSPGTIETDFHERYSSREKLEQTRKSIPLQRLGTAEDCAPAYLFLAAPLLSG YITGQVIEINGGQLIC >Mature_256_residues MFHPRLFENRNVVVTGAGRGIGLEVARQFLDCGAKVIVHTGRKPGRDLPDFLLTAESERRALLLHADFSAAGGAAQFADD VLAFFDRVHVLVNNAGTMLGRFPAATLTDAEYEAVIRLNQTSVVALTRALLPALKAAEGAAVVNTVSISALTGGSPGSSI YSASKAFVATYSKALARELAPDGIRVNCVSPGTIETDFHERYSSREKLEQTRKSIPLQRLGTAEDCAPAYLFLAAPLLSG YITGQVIEINGGQLIC
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=31.2, Blast_Score=105, Evalue=4e-23, Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=28.1853281853282, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI5031737, Length=251, Percent_Identity=31.0756972111554, Blast_Score=99, Evalue=4e-21, Organism=Homo sapiens, GI10190704, Length=267, Percent_Identity=29.9625468164794, Blast_Score=98, Evalue=7e-21, Organism=Homo sapiens, GI40254992, Length=170, Percent_Identity=38.2352941176471, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI66933014, Length=194, Percent_Identity=31.4432989690722, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI126723750, Length=251, Percent_Identity=26.6932270916335, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI59889578, Length=238, Percent_Identity=27.3109243697479, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI15277342, Length=249, Percent_Identity=31.3253012048193, Blast_Score=80, Evalue=3e-15, Organism=Homo sapiens, GI20149619, Length=201, Percent_Identity=32.8358208955224, Blast_Score=75, Evalue=8e-14, Organism=Homo sapiens, GI33667109, Length=199, Percent_Identity=30.1507537688442, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=26.2096774193548, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI4557649, Length=185, Percent_Identity=27.5675675675676, Blast_Score=66, Evalue=4e-11, Organism=Homo sapiens, GI4504505, Length=197, Percent_Identity=28.9340101522843, Blast_Score=64, Evalue=1e-10, Organism=Escherichia coli, GI1787335, Length=255, Percent_Identity=34.1176470588235, Blast_Score=114, Evalue=6e-27, Organism=Escherichia coli, GI2367175, Length=252, Percent_Identity=32.1428571428571, Blast_Score=100, Evalue=8e-23, Organism=Escherichia coli, GI1789378, Length=249, Percent_Identity=29.718875502008, Blast_Score=95, Evalue=4e-21, Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=32.1705426356589, Blast_Score=92, Evalue=4e-20, Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=30.7086614173228, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1789208, Length=250, Percent_Identity=29.2, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=28.1124497991968, Blast_Score=82, Evalue=5e-17, Organism=Escherichia coli, GI87082160, Length=253, Percent_Identity=25.296442687747, Blast_Score=81, Evalue=7e-17, Organism=Escherichia coli, GI1787820, Length=235, Percent_Identity=30.2127659574468, Blast_Score=81, Evalue=8e-17, Organism=Escherichia coli, GI1790717, Length=258, Percent_Identity=25.968992248062, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1786701, Length=217, Percent_Identity=30.4147465437788, Blast_Score=71, Evalue=7e-14, Organism=Escherichia coli, GI1788459, Length=248, Percent_Identity=26.6129032258064, Blast_Score=71, Evalue=8e-14, Organism=Escherichia coli, GI1787891, Length=244, Percent_Identity=26.6393442622951, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI2367365, Length=247, Percent_Identity=27.9352226720648, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI1787526, Length=251, Percent_Identity=27.8884462151394, Blast_Score=62, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=34.8484848484849, Blast_Score=117, Evalue=6e-27, Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=33.3333333333333, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=32.4427480916031, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17560676, Length=254, Percent_Identity=32.2834645669291, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=29.3650793650794, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17538480, Length=261, Percent_Identity=32.9501915708812, Blast_Score=103, Evalue=6e-23, Organism=Caenorhabditis elegans, GI17562908, Length=260, Percent_Identity=32.3076923076923, Blast_Score=103, Evalue=7e-23, Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=31.1538461538462, Blast_Score=103, Evalue=8e-23, Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=33.587786259542, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17562990, Length=258, Percent_Identity=32.5581395348837, Blast_Score=100, Evalue=6e-22, Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=32.5581395348837, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17531453, Length=271, Percent_Identity=30.6273062730627, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI72000259, Length=259, Percent_Identity=30.5019305019305, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=30.9803921568627, Blast_Score=97, Evalue=8e-21, Organism=Caenorhabditis elegans, GI17565030, Length=269, Percent_Identity=32.3420074349442, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=30.4347826086957, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17555706, Length=254, Percent_Identity=29.1338582677165, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17538486, Length=269, Percent_Identity=29.7397769516729, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17562910, Length=266, Percent_Identity=30.4511278195489, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI25147288, Length=260, Percent_Identity=30, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17544670, Length=278, Percent_Identity=27.6978417266187, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=29.5019157088123, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=29.277566539924, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17563726, Length=260, Percent_Identity=28.8461538461538, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI17558990, Length=209, Percent_Identity=29.1866028708134, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17536651, Length=254, Percent_Identity=27.9527559055118, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI72001658, Length=233, Percent_Identity=28.3261802575107, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI115534694, Length=249, Percent_Identity=26.5060240963855, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17536025, Length=253, Percent_Identity=27.2727272727273, Blast_Score=64, Evalue=7e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=231, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=7e-17, Organism=Saccharomyces cerevisiae, GI6324126, Length=166, Percent_Identity=31.9277108433735, Blast_Score=78, Evalue=2e-15, Organism=Saccharomyces cerevisiae, GI6322861, Length=198, Percent_Identity=31.3131313131313, Blast_Score=75, Evalue=1e-14, Organism=Drosophila melanogaster, GI23397609, Length=258, Percent_Identity=34.1085271317829, Blast_Score=111, Evalue=6e-25, Organism=Drosophila melanogaster, GI28571526, Length=256, Percent_Identity=32.8125, Blast_Score=102, Evalue=2e-22, Organism=Drosophila melanogaster, GI21355319, Length=251, Percent_Identity=30.2788844621514, Blast_Score=99, Evalue=3e-21, Organism=Drosophila melanogaster, GI21357041, Length=260, Percent_Identity=31.1538461538462, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI24644339, Length=260, Percent_Identity=29.2307692307692, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI24643142, Length=242, Percent_Identity=33.0578512396694, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI24639444, Length=245, Percent_Identity=33.469387755102, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI21358495, Length=209, Percent_Identity=30.622009569378, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI24644337, Length=179, Percent_Identity=36.3128491620112, Blast_Score=77, Evalue=8e-15, Organism=Drosophila melanogaster, GI24584744, Length=194, Percent_Identity=31.4432989690722, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI28574402, Length=194, Percent_Identity=31.4432989690722, Blast_Score=73, Evalue=1e-13, Organism=Drosophila melanogaster, GI24665243, Length=205, Percent_Identity=25.3658536585366, Blast_Score=65, Evalue=6e-11, Organism=Drosophila melanogaster, GI221331218, Length=205, Percent_Identity=25.3658536585366, Blast_Score=65, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 27231; Mature: 27231
Theoretical pI: Translated: 7.50; Mature: 7.50
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 0.8 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 0.8 %Met (Mature Protein) 2.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MFHPRLFENRNVVVTGAGRGIGLEVARQFLDCGAKVIVHTGRKPGRDLPDFLLTAESERR CCCCCEECCCCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCHHHEECCCCCC ALLLHADFSAAGGAAQFADDVLAFFDRVHVLVNNAGTMLGRFPAATLTDAEYEAVIRLNQ EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEECCCCEEEEEEECC TSVVALTRALLPALKAAEGAAVVNTVSISALTGGSPGSSIYSASKAFVATYSKALARELA HHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHC PDGIRVNCVSPGTIETDFHERYSSREKLEQTRKSIPLQRLGTAEDCAPAYLFLAAPLLSG CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHH YITGQVIEINGGQLIC HHCCEEEEECCCEEEC >Mature Secondary Structure MFHPRLFENRNVVVTGAGRGIGLEVARQFLDCGAKVIVHTGRKPGRDLPDFLLTAESERR CCCCCEECCCCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCHHHEECCCCCC ALLLHADFSAAGGAAQFADDVLAFFDRVHVLVNNAGTMLGRFPAATLTDAEYEAVIRLNQ EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEECCCCEEEEEEECC TSVVALTRALLPALKAAEGAAVVNTVSISALTGGSPGSSIYSASKAFVATYSKALARELA HHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHC PDGIRVNCVSPGTIETDFHERYSSREKLEQTRKSIPLQRLGTAEDCAPAYLFLAAPLLSG CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHH YITGQVIEINGGQLIC HHCCEEEEECCCEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9163424 [H]