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The map label for this gene is oxyR [H]

Identifier: 209551213

GI number: 209551213

Start: 3770772

End: 3771665

Strand: Reverse

Name: oxyR [H]

Synonym: Rleg2_3639

Alternate gene names: 209551213

Gene position: 3771665-3770772 (Counterclockwise)

Preceding gene: 209551214

Following gene: 209551212

Centisome position: 83.11

GC content: 62.3

Gene sequence:

>894_bases
ATGATCGACAAGCTGGAATTCTTCATCGCCCTTGCCAATGAGAAGCATTTCGGCCGCGCTGCGGAGGAGTGCGGGATTTC
GCAGCCGACGCTTTCGGCCGCGATCCGCCAGCTCGAGGATCAGCTCGGGGTCATGCTGGTGCAGCGCGGTTCGCGTTTTC
AAGGGTTGACGCCGGAGGGGCAGCGCGTGCTCGAATGGGCCCGGCGCATCGTCGGCGACGCCCGCACCATGCGCGAGGAG
ATGCGCGCCGCCCGCCGCGGCCTTTCAGGCCACATTCGCCTTGCCGCCATTCCGACGGCGCTCGCCATGCTTTCGCGCAT
TACCACGCCTTTCCAGGAGCGGCATCCCGGCGTCACCTTCTCGATCGTCTCGCGCAATTCGCTGCAGGTGCTGAGCATGC
TCGAAAACCTCGAAATCGATGCCGGCATCACCTATCTCGAAAACGAGCCGCTCGGCCGTGTCACCAGCGTTCCGCTCTAT
GCCGAGCGCTATCATCTGATCACGGCAGCAGGCAGCCCGCTTTCCGATCGCGACAATGTGACCTGGAAGGAAGTCGGCGA
TCTTCGGCTTTGTCTATTGACCGCCGACATGCAGAACCGCCGAATCATCAACCGGCACCTGACCGAAGCCGGCGCCACGG
TGCATCCGACGCTCGAATCCAACTCGATGATCGTGCTGTTTTCGCATGTTCGAACCGGCCGCTGGGCGAGTATCATGCCG
CGCAATGTCGCCAAATCTTTTGGTTTTCCGGTGGAAATCCGGATGATTCCGATCGTCGAGCCGGAGGCGCATCACCTGGT
CGGGCTTGTGGCACCCTATCGTGAGCCCTTCACGCCGCTGGTCTCGGCCTTGCTGCACGAGGCCAGAGTGCTCGTGCAGG
ACGAGGAACTCTGA

Upstream 100 bases:

>100_bases
AAACTGTTAAAGCGCGTCGCCTTAACTTGATTCATTCCCTTGCGGAGCACGGTTGCTGTGTCGAAGATGAGGCCGGACGC
GAAATGTCGCGGGAGACCGG

Downstream 100 bases:

>100_bases
TAGAAAAAACCTATCAACCGACGTGATAGCTTTATTGATCGCCGGCGGCTTCCTTGAGATGCTGTCGGCGGAATAGCACT
CGGGCTGGAGGAGGCCGCCA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Morphology and auto-aggregation control protein [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MIDKLEFFIALANEKHFGRAAEECGISQPTLSAAIRQLEDQLGVMLVQRGSRFQGLTPEGQRVLEWARRIVGDARTMREE
MRAARRGLSGHIRLAAIPTALAMLSRITTPFQERHPGVTFSIVSRNSLQVLSMLENLEIDAGITYLENEPLGRVTSVPLY
AERYHLITAAGSPLSDRDNVTWKEVGDLRLCLLTADMQNRRIINRHLTEAGATVHPTLESNSMIVLFSHVRTGRWASIMP
RNVAKSFGFPVEIRMIPIVEPEAHHLVGLVAPYREPFTPLVSALLHEARVLVQDEEL

Sequences:

>Translated_297_residues
MIDKLEFFIALANEKHFGRAAEECGISQPTLSAAIRQLEDQLGVMLVQRGSRFQGLTPEGQRVLEWARRIVGDARTMREE
MRAARRGLSGHIRLAAIPTALAMLSRITTPFQERHPGVTFSIVSRNSLQVLSMLENLEIDAGITYLENEPLGRVTSVPLY
AERYHLITAAGSPLSDRDNVTWKEVGDLRLCLLTADMQNRRIINRHLTEAGATVHPTLESNSMIVLFSHVRTGRWASIMP
RNVAKSFGFPVEIRMIPIVEPEAHHLVGLVAPYREPFTPLVSALLHEARVLVQDEEL
>Mature_297_residues
MIDKLEFFIALANEKHFGRAAEECGISQPTLSAAIRQLEDQLGVMLVQRGSRFQGLTPEGQRVLEWARRIVGDARTMREE
MRAARRGLSGHIRLAAIPTALAMLSRITTPFQERHPGVTFSIVSRNSLQVLSMLENLEIDAGITYLENEPLGRVTSVPLY
AERYHLITAAGSPLSDRDNVTWKEVGDLRLCLLTADMQNRRIINRHLTEAGATVHPTLESNSMIVLFSHVRTGRWASIMP
RNVAKSFGFPVEIRMIPIVEPEAHHLVGLVAPYREPFTPLVSALLHEARVLVQDEEL

Specific function: Hydrogen peroxide sensor. Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA. OxyR expression is negatively autoregulated by binding to a 43 bp region upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=287, Percent_Identity=29.616724738676, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI157672245, Length=262, Percent_Identity=27.4809160305344, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788748, Length=266, Percent_Identity=27.8195488721804, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI2367136, Length=179, Percent_Identity=33.5195530726257, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI145693105, Length=270, Percent_Identity=25.1851851851852, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786401, Length=173, Percent_Identity=31.7919075144509, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87081904, Length=184, Percent_Identity=29.8913043478261, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787879, Length=193, Percent_Identity=31.0880829015544, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788296, Length=211, Percent_Identity=26.0663507109005, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788887, Length=181, Percent_Identity=32.5966850828729, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87081978, Length=94, Percent_Identity=35.1063829787234, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33283; Mature: 33283

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDKLEFFIALANEKHFGRAAEECGISQPTLSAAIRQLEDQLGVMLVQRGSRFQGLTPEG
CCCCEEEEEEECCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCH
QRVLEWARRIVGDARTMREEMRAARRGLSGHIRLAAIPTALAMLSRITTPFQERHPGVTF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHCCCHHHHCCCEEE
SIVSRNSLQVLSMLENLEIDAGITYLENEPLGRVTSVPLYAERYHLITAAGSPLSDRDNV
EEECCCHHHHHHHHHHCCCCCCEEEECCCCCCCEECCCEEHHHEEEEEECCCCCCCCCCC
TWKEVGDLRLCLLTADMQNRRIINRHLTEAGATVHPTLESNSMIVLFSHVRTGRWASIMP
CHHHHCCEEEEEEECCCCCCHHHHHHHHHCCCEEECCCCCCCEEEEEECCCCCCCHHHCC
RNVAKSFGFPVEIRMIPIVEPEAHHLVGLVAPYREPFTPLVSALLHEARVLVQDEEL
HHHHHHCCCCEEEEEEEEECCCHHHHEEECCCCCCCHHHHHHHHHHHHHHHEECCCC
>Mature Secondary Structure
MIDKLEFFIALANEKHFGRAAEECGISQPTLSAAIRQLEDQLGVMLVQRGSRFQGLTPEG
CCCCEEEEEEECCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCH
QRVLEWARRIVGDARTMREEMRAARRGLSGHIRLAAIPTALAMLSRITTPFQERHPGVTF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHCCCHHHHCCCEEE
SIVSRNSLQVLSMLENLEIDAGITYLENEPLGRVTSVPLYAERYHLITAAGSPLSDRDNV
EEECCCHHHHHHHHHHCCCCCCEEEECCCCCCCEECCCEEHHHEEEEEECCCCCCCCCCC
TWKEVGDLRLCLLTADMQNRRIINRHLTEAGATVHPTLESNSMIVLFSHVRTGRWASIMP
CHHHHCCEEEEEEECCCCCCHHHHHHHHHCCCEEECCCCCCCEEEEEECCCCCCCHHHCC
RNVAKSFGFPVEIRMIPIVEPEAHHLVGLVAPYREPFTPLVSALLHEARVLVQDEEL
HHHHHHCCCCEEEEEEEEECCCHHHHEEECCCCCCCHHHHHHHHHHHHHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]