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The map label for this gene is mcpA [H]

Identifier: 209551206

GI number: 209551206

Start: 3760765

End: 3762543

Strand: Direct

Name: mcpA [H]

Synonym: Rleg2_3632

Alternate gene names: 209551206

Gene position: 3760765-3762543 (Clockwise)

Preceding gene: 209551205

Following gene: 209551217

Centisome position: 82.87

GC content: 61.66

Gene sequence:

>1779_bases
ATGTTTGGTCTAGCCTCCGATTCGAAATACATTCTTGACGCCATCTCCAAATCGCAGGCGATCATCGAATTCGATCTCAA
CGGCAATATTCTCACGGCGAACGAGAATTTCTGCAACGCCCTGGGTTATCGCCTCAACGAGATCGTCGGCAAGCATCACA
GCATGTTCTGCGAACCGGCCTACACGGCGACGCCCGAATATCGCGCCTTCTGGGCGCGGCTCGGACGCGGCGAATATGAT
GCCGGCGCCTATAAGCGTCTTGCCAAGGGCAACAGGGAGATATGGATCCAGGCGTCCTATAATCCCGTTTCCAAAGGCGG
AAAGCCGTTCAAGGTGGTGAAATTCGCCGCCGACATCACAGCGGCGAAAAAGCAGGCGGTCGAAGATTCCGGCAAACTGG
AAGCGATCTCGCGCTCGCAGGCAGTGATCGAATTCACCCCGAAGGGCGACATCCTGACTGCGAACGAGAATTTCTGCCAG
GCCATGGGATATTCGCTGGCCGAAATCGCCGGCAAACATCACAGCATCTTCTGCGACCCGGCCCATACCCGCACCGAGGA
ATACAGCAGCTTCTGGCGGCGTCTTGCCAATGGCGAATTCATCGCCAACGAATTCGTCCGCTTCGGCAAGGGCGGCCGCG
AAATCTGGATCCAGGCAGCTTATAACCCGATCGTCGATGCCGACGGCAAAGTCTATAAAGTCGTGAAGTTCGCGACCGAC
GTCACCCAGCGGATGAGCGCGATTTCCCAGCTCGGCGGCGCGCTGCGCCAGCTTTCCGAAGGTGATCTGACGATGACGGT
GGACACGCCCTTCGTCCCCTCGATGGAGCAGCTGCGCCACGACTTCAACACTGCGGTCAAAGGTCTTGCCGATACGATGA
AGACCATCGGCGAGAATGCCGTTGCGATCGCCGCCGGGTCGAGCGAGATCGGTACATCGGCGGACTCCTTTTCCAAGCGG
ACGGAACAGCAGGCCGCGTCGATCGAAGAAACCGCAGCCGCGCTGGAGGAGATCACCACCACCGTCAACGATTCCAGTCG
CCGCGCCGATGAGGCGGGCCGCCTTGTCGCCGTGACCAAGCAGGGCGCCGAGCAATCGGGCGTCGTGGTCCGCAACGCCG
TCGCCGCCATGGACCAGATCGAGCAGTCCTCGCGCGAAATCACCAATATCATCGGCGTCATCGACGATATCGCCTTCCAG
ACCAATCTCCTGGCGCTGAATGCCGGCGTCGAAGCCGCCCGCGCCGGCGAAGCCGGCAAGGGTTTCGCTGTGGTGGCCCA
GGAAGTCCGCGAGCTCGCCCAGCGCTCCGCCAAGGCGGCCAAGGAGATCAAGGCGCTGATCAATACGTCGAGCGAGCTCG
TCAAAAACGGCGTCGGCCTCGTCGGCCAGACCGGCAAGGCGCTCGAGGAGATCGTCACCCAGGTTGGCGATATCAACGGC
AACGTCGTCGCCATCGTCGAAGCCTCACGGGAACAGGCAACCGGCCTCAAGGAAATCAACCAGGCGGTCAATTCGCTCGA
CCAGGCAACCCAGCAGAATGCCGCCATGGTCGAGGAGAGCACCGCCGCCAGCCATAGCCTGGCAAAGGAAGCCGAAACGC
TGCGGGTCCTGCTGGCACGGTTCCGCCTGCCCGGTCAGACCCGCACCCAGGCCGGGCCTCAGACCGCCGGCAGGCTGGAA
ACAAGACAGACAGGCTCGCCGGCACTGCATCTCGTTTCCCGCGTCGGCAAGGCGTACGGCGCTGCCGCTGCAACGGCGCA
GAGCTGGGAAGAGTTCTGA

Upstream 100 bases:

>100_bases
GATAACCGGAGACCGGTTGTCCCCTGCACCGGCATACCTCGCCAGCCCCTTCGCTTCTCCAGCCGAAACAGCGCAAGCTG
TGCATCTCAAAGGGACAAGA

Downstream 100 bases:

>100_bases
GCCACGCCCCATAGCTCGCGATTGTTTCTGCGTAGCGAGGAAGAAGCGCGCCGCATGAGGCCCATGCGGCGCGCTTTGAT
ATCTCACCCGAACAGCGCGA

Product: methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
MFGLASDSKYILDAISKSQAIIEFDLNGNILTANENFCNALGYRLNEIVGKHHSMFCEPAYTATPEYRAFWARLGRGEYD
AGAYKRLAKGNREIWIQASYNPVSKGGKPFKVVKFAADITAAKKQAVEDSGKLEAISRSQAVIEFTPKGDILTANENFCQ
AMGYSLAEIAGKHHSIFCDPAHTRTEEYSSFWRRLANGEFIANEFVRFGKGGREIWIQAAYNPIVDADGKVYKVVKFATD
VTQRMSAISQLGGALRQLSEGDLTMTVDTPFVPSMEQLRHDFNTAVKGLADTMKTIGENAVAIAAGSSEIGTSADSFSKR
TEQQAASIEETAAALEEITTTVNDSSRRADEAGRLVAVTKQGAEQSGVVVRNAVAAMDQIEQSSREITNIIGVIDDIAFQ
TNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRSAKAAKEIKALINTSSELVKNGVGLVGQTGKALEEIVTQVGDING
NVVAIVEASREQATGLKEINQAVNSLDQATQQNAAMVEESTAASHSLAKEAETLRVLLARFRLPGQTRTQAGPQTAGRLE
TRQTGSPALHLVSRVGKAYGAAAATAQSWEEF

Sequences:

>Translated_592_residues
MFGLASDSKYILDAISKSQAIIEFDLNGNILTANENFCNALGYRLNEIVGKHHSMFCEPAYTATPEYRAFWARLGRGEYD
AGAYKRLAKGNREIWIQASYNPVSKGGKPFKVVKFAADITAAKKQAVEDSGKLEAISRSQAVIEFTPKGDILTANENFCQ
AMGYSLAEIAGKHHSIFCDPAHTRTEEYSSFWRRLANGEFIANEFVRFGKGGREIWIQAAYNPIVDADGKVYKVVKFATD
VTQRMSAISQLGGALRQLSEGDLTMTVDTPFVPSMEQLRHDFNTAVKGLADTMKTIGENAVAIAAGSSEIGTSADSFSKR
TEQQAASIEETAAALEEITTTVNDSSRRADEAGRLVAVTKQGAEQSGVVVRNAVAAMDQIEQSSREITNIIGVIDDIAFQ
TNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRSAKAAKEIKALINTSSELVKNGVGLVGQTGKALEEIVTQVGDING
NVVAIVEASREQATGLKEINQAVNSLDQATQQNAAMVEESTAASHSLAKEAETLRVLLARFRLPGQTRTQAGPQTAGRLE
TRQTGSPALHLVSRVGKAYGAAAATAQSWEEF
>Mature_592_residues
MFGLASDSKYILDAISKSQAIIEFDLNGNILTANENFCNALGYRLNEIVGKHHSMFCEPAYTATPEYRAFWARLGRGEYD
AGAYKRLAKGNREIWIQASYNPVSKGGKPFKVVKFAADITAAKKQAVEDSGKLEAISRSQAVIEFTPKGDILTANENFCQ
AMGYSLAEIAGKHHSIFCDPAHTRTEEYSSFWRRLANGEFIANEFVRFGKGGREIWIQAAYNPIVDADGKVYKVVKFATD
VTQRMSAISQLGGALRQLSEGDLTMTVDTPFVPSMEQLRHDFNTAVKGLADTMKTIGENAVAIAAGSSEIGTSADSFSKR
TEQQAASIEETAAALEEITTTVNDSSRRADEAGRLVAVTKQGAEQSGVVVRNAVAAMDQIEQSSREITNIIGVIDDIAFQ
TNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRSAKAAKEIKALINTSSELVKNGVGLVGQTGKALEEIVTQVGDING
NVVAIVEASREQATGLKEINQAVNSLDQATQQNAAMVEESTAASHSLAKEAETLRVLLARFRLPGQTRTQAGPQTAGRLE
TRQTGSPALHLVSRVGKAYGAAAATAQSWEEF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=331, Percent_Identity=41.9939577039275, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI2367378, Length=358, Percent_Identity=42.4581005586592, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1787690, Length=311, Percent_Identity=41.4790996784566, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1788194, Length=265, Percent_Identity=45.2830188679245, Blast_Score=189, Evalue=4e-49,
Organism=Escherichia coli, GI1789453, Length=229, Percent_Identity=40.6113537117904, Blast_Score=161, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 63570; Mature: 63570

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGLASDSKYILDAISKSQAIIEFDLNGNILTANENFCNALGYRLNEIVGKHHSMFCEPA
CCCCCCCCHHHHHHHCCCCEEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHEEECCC
YTATPEYRAFWARLGRGEYDAGAYKRLAKGNREIWIQASYNPVSKGGKPFKVVKFAADIT
CCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEECCCHHCCCCCCEEEEHHHHHHH
AAKKQAVEDSGKLEAISRSQAVIEFTPKGDILTANENFCQAMGYSLAEIAGKHHSIFCDP
HHHHHHHHCCCCCHHCCCCCEEEEECCCCCEEECCHHHHHHHCCHHHHHCCCCCEEEECC
AHTRTEEYSSFWRRLANGEFIANEFVRFGKGGREIWIQAAYNPIVDADGKVYKVVKFATD
CCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEHHHHHHHH
VTQRMSAISQLGGALRQLSEGDLTMTVDTPFVPSMEQLRHDFNTAVKGLADTMKTIGENA
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
VAIAAGSSEIGTSADSFSKRTEQQAASIEETAAALEEITTTVNDSSRRADEAGRLVAVTK
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEEEEC
QGAEQSGVVVRNAVAAMDQIEQSSREITNIIGVIDDIAFQTNLLALNAGVEAARAGEAGK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHCCCCCC
GFAVVAQEVRELAQRSAKAAKEIKALINTSSELVKNGVGLVGQTGKALEEIVTQVGDING
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCC
NVVAIVEASREQATGLKEINQAVNSLDQATQQNAAMVEESTAASHSLAKEAETLRVLLAR
CEEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRLPGQTRTQAGPQTAGRLETRQTGSPALHLVSRVGKAYGAAAATAQSWEEF
HCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFGLASDSKYILDAISKSQAIIEFDLNGNILTANENFCNALGYRLNEIVGKHHSMFCEPA
CCCCCCCCHHHHHHHCCCCEEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHEEECCC
YTATPEYRAFWARLGRGEYDAGAYKRLAKGNREIWIQASYNPVSKGGKPFKVVKFAADIT
CCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEECCCHHCCCCCCEEEEHHHHHHH
AAKKQAVEDSGKLEAISRSQAVIEFTPKGDILTANENFCQAMGYSLAEIAGKHHSIFCDP
HHHHHHHHCCCCCHHCCCCCEEEEECCCCCEEECCHHHHHHHCCHHHHHCCCCCEEEECC
AHTRTEEYSSFWRRLANGEFIANEFVRFGKGGREIWIQAAYNPIVDADGKVYKVVKFATD
CCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEHHHHHHHH
VTQRMSAISQLGGALRQLSEGDLTMTVDTPFVPSMEQLRHDFNTAVKGLADTMKTIGENA
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
VAIAAGSSEIGTSADSFSKRTEQQAASIEETAAALEEITTTVNDSSRRADEAGRLVAVTK
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEEEEC
QGAEQSGVVVRNAVAAMDQIEQSSREITNIIGVIDDIAFQTNLLALNAGVEAARAGEAGK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHCCCCCC
GFAVVAQEVRELAQRSAKAAKEIKALINTSSELVKNGVGLVGQTGKALEEIVTQVGDING
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCC
NVVAIVEASREQATGLKEINQAVNSLDQATQQNAAMVEESTAASHSLAKEAETLRVLLAR
CEEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRLPGQTRTQAGPQTAGRLETRQTGSPALHLVSRVGKAYGAAAATAQSWEEF
HCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]