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The map label for this gene is rocD [H]

Identifier: 209551204

GI number: 209551204

Start: 3758598

End: 3759797

Strand: Direct

Name: rocD [H]

Synonym: Rleg2_3630

Alternate gene names: 209551204

Gene position: 3758598-3759797 (Clockwise)

Preceding gene: 209551203

Following gene: 209551205

Centisome position: 82.83

GC content: 62.67

Gene sequence:

>1200_bases
ATGAACACTTCGGAAAAACTGATCGCCACCGAACAGCGTCTCGGCGCCCACAATTACAAGCCGCTCGACGTGGTGCTGAC
CCGCGGCGAAGGTGTTCATGTCTGGGATACCGACGGCAATCGTTACCTCGATTGCCTCTCGGCCTATTCCGCCGTCAACC
AGGGCCATTGTCACCCGAAAATCCTCGCCGCCATGGTCGAGCAGGCGGGAAGATTGACGCTGACCTCCCGCGCCTTCCGC
AACGATCAGCTCGCTTATCTCTATGAAGAGCTCGCGGCGTTGACCGGATCGCACAAGATCCTGCCGATGAACTCAGGCGC
CGAAGCGGTGGAGACCGCCATCAAGGCGGTGCGCAAATGGGGATACGAGGTCAAAGGTGTACCGGAAGGCCAGGCCGAGA
TCATCGTCTGCGCCGATAATTTCCATGGCCGGACGCTGAGCATCATCAGTTTCTCCACCGATCCCGACGCCCGCACCGGC
TTCGGCCCCTACACCTCGGGCTTCCGCACCATTCCCTTCGGCGATGCCGAAGCCTTCGAGGCCGCCATCAACGGCAATAC
GGTCGCCGCCCTGATCGAGCCGATCCAGGGGGAAGCCGGCGTCATCATCCCGCCGGCCGGATACTTCACCCGCATCCGCG
AGCTCTGCACCGATAACAACGTCACTCTCATCCTCGACGAGATCCAGACCGGCCTCGGCCGCACCGGCAAGCTCTTGGCG
GAGGAACATGAAGGCATCGAGGCCGATGTGACGCTGATCGGCAAGGCGCTGTCCGGCGGCTTCTATCCCGTCTCGGCGGT
GCTTTCCAATTCCGCGGTACTGGGGGTGCTGAAGCCCGGCCAGCATGGCTCCACTTTCGGCGGCAATCCGCTCGCCTGCG
CAGTGGCGCGCGCCGCGCTGAAGGTGCTGACGGAAGAGGGCATGATCGAGAACGCCGCTGATATGGGCGACTATTTCCTC
GAAGGCCTCAGGTCGATCCGCTCGAACATCGTCAGGGACGTGCGCGGCCGCGGCCTGATGATGGCTGTCGAACTGGAACC
CGAGGCCGGCGGCGCGCGGCAATATTGTCATGCGCTGAAGGAACGCGGCCTGCTCGCCAAGGATACGCATGACCATACGA
TTCGCCTCGCTCCGCCGCTGGTCATCACCAGGGAGCAGGTCGATTGGGCGGTCTCGCAGATCGAAAAGACCATAAGCTGA

Upstream 100 bases:

>100_bases
ACGGCAAGCCTCTTCGGCCGCCGCATCTTCGATCGCCCAACCCGCGCCGCATAGTAGGCGCGCCCGCCTATCGGCATCAT
GATCTAGAGGGGGAAGAACC

Downstream 100 bases:

>100_bases
GGTCAATCGAGGACGAAACCTTCGCAAATCCGGTTCCCGATTTAGATTTGGGCAACACTCTTCCGCTAATGTCGTCGATA
ACCGTAACGATGCTGGGCCG

Product: ornithine--oxo-acid transaminase

Products: NA

Alternate protein names: OAT; Ornithine--oxo-acid aminotransferase [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MNTSEKLIATEQRLGAHNYKPLDVVLTRGEGVHVWDTDGNRYLDCLSAYSAVNQGHCHPKILAAMVEQAGRLTLTSRAFR
NDQLAYLYEELAALTGSHKILPMNSGAEAVETAIKAVRKWGYEVKGVPEGQAEIIVCADNFHGRTLSIISFSTDPDARTG
FGPYTSGFRTIPFGDAEAFEAAINGNTVAALIEPIQGEAGVIIPPAGYFTRIRELCTDNNVTLILDEIQTGLGRTGKLLA
EEHEGIEADVTLIGKALSGGFYPVSAVLSNSAVLGVLKPGQHGSTFGGNPLACAVARAALKVLTEEGMIENAADMGDYFL
EGLRSIRSNIVRDVRGRGLMMAVELEPEAGGARQYCHALKERGLLAKDTHDHTIRLAPPLVITREQVDWAVSQIEKTIS

Sequences:

>Translated_399_residues
MNTSEKLIATEQRLGAHNYKPLDVVLTRGEGVHVWDTDGNRYLDCLSAYSAVNQGHCHPKILAAMVEQAGRLTLTSRAFR
NDQLAYLYEELAALTGSHKILPMNSGAEAVETAIKAVRKWGYEVKGVPEGQAEIIVCADNFHGRTLSIISFSTDPDARTG
FGPYTSGFRTIPFGDAEAFEAAINGNTVAALIEPIQGEAGVIIPPAGYFTRIRELCTDNNVTLILDEIQTGLGRTGKLLA
EEHEGIEADVTLIGKALSGGFYPVSAVLSNSAVLGVLKPGQHGSTFGGNPLACAVARAALKVLTEEGMIENAADMGDYFL
EGLRSIRSNIVRDVRGRGLMMAVELEPEAGGARQYCHALKERGLLAKDTHDHTIRLAPPLVITREQVDWAVSQIEKTIS
>Mature_399_residues
MNTSEKLIATEQRLGAHNYKPLDVVLTRGEGVHVWDTDGNRYLDCLSAYSAVNQGHCHPKILAAMVEQAGRLTLTSRAFR
NDQLAYLYEELAALTGSHKILPMNSGAEAVETAIKAVRKWGYEVKGVPEGQAEIIVCADNFHGRTLSIISFSTDPDARTG
FGPYTSGFRTIPFGDAEAFEAAINGNTVAALIEPIQGEAGVIIPPAGYFTRIRELCTDNNVTLILDEIQTGLGRTGKLLA
EEHEGIEADVTLIGKALSGGFYPVSAVLSNSAVLGVLKPGQHGSTFGGNPLACAVARAALKVLTEEGMIENAADMGDYFL
EGLRSIRSNIVRDVRGRGLMMAVELEPEAGGARQYCHALKERGLLAKDTHDHTIRLAPPLVITREQVDWAVSQIEKTIS

Specific function: Catalyzes the interconversion of ornithine to glutamate semialdehyde [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=398, Percent_Identity=52.0100502512563, Blast_Score=416, Evalue=1e-116,
Organism=Homo sapiens, GI284507298, Length=298, Percent_Identity=51.6778523489933, Blast_Score=299, Evalue=3e-81,
Organism=Homo sapiens, GI13994255, Length=437, Percent_Identity=29.9771167048055, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI37574042, Length=418, Percent_Identity=27.0334928229665, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI24119277, Length=440, Percent_Identity=27.9545454545455, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI226442709, Length=384, Percent_Identity=26.8229166666667, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI226442705, Length=418, Percent_Identity=26.0765550239234, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI188536080, Length=408, Percent_Identity=24.7549019607843, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI38679950, Length=408, Percent_Identity=24.7549019607843, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI38679946, Length=408, Percent_Identity=24.7549019607843, Blast_Score=96, Evalue=9e-20,
Organism=Escherichia coli, GI145693181, Length=378, Percent_Identity=38.3597883597884, Blast_Score=255, Evalue=3e-69,
Organism=Escherichia coli, GI1789759, Length=384, Percent_Identity=34.8958333333333, Blast_Score=248, Evalue=3e-67,
Organism=Escherichia coli, GI1788044, Length=372, Percent_Identity=35.2150537634409, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI1789016, Length=436, Percent_Identity=30.2752293577982, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI1787560, Length=400, Percent_Identity=31.25, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1786991, Length=425, Percent_Identity=31.0588235294118, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1786349, Length=312, Percent_Identity=26.2820512820513, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI25144271, Length=398, Percent_Identity=51.5075376884422, Blast_Score=435, Evalue=1e-122,
Organism=Caenorhabditis elegans, GI25144274, Length=288, Percent_Identity=48.6111111111111, Blast_Score=284, Evalue=6e-77,
Organism=Caenorhabditis elegans, GI71981843, Length=173, Percent_Identity=50.8670520231214, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI32564660, Length=432, Percent_Identity=30.5555555555556, Blast_Score=177, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI71992977, Length=422, Percent_Identity=27.2511848341232, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17541228, Length=424, Percent_Identity=24.5283018867925, Blast_Score=98, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6323470, Length=415, Percent_Identity=49.1566265060241, Blast_Score=390, Evalue=1e-109,
Organism=Saccharomyces cerevisiae, GI6324432, Length=397, Percent_Identity=31.4861460957179, Blast_Score=192, Evalue=8e-50,
Organism=Saccharomyces cerevisiae, GI6321456, Length=428, Percent_Identity=24.0654205607477, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324386, Length=427, Percent_Identity=23.4192037470726, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI21357415, Length=396, Percent_Identity=53.7878787878788, Blast_Score=426, Evalue=1e-119,
Organism=Drosophila melanogaster, GI161085790, Length=461, Percent_Identity=30.1518438177874, Blast_Score=161, Evalue=6e-40,
Organism=Drosophila melanogaster, GI28574759, Length=461, Percent_Identity=30.3687635574837, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI21356575, Length=413, Percent_Identity=28.8135593220339, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI281366494, Length=423, Percent_Identity=25.7683215130024, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24667139, Length=423, Percent_Identity=25.7683215130024, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24667143, Length=423, Percent_Identity=25.7683215130024, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR010164
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.13 [H]

Molecular weight: Translated: 42968; Mature: 42968

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTSEKLIATEQRLGAHNYKPLDVVLTRGEGVHVWDTDGNRYLDCLSAYSAVNQGHCHPK
CCCCHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEECCCCHHHHHHHHHHHHCCCCCCHH
ILAAMVEQAGRLTLTSRAFRNDQLAYLYEELAALTGSHKILPMNSGAEAVETAIKAVRKW
HHHHHHHHCCCEEEEHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHC
GYEVKGVPEGQAEIIVCADNFHGRTLSIISFSTDPDARTGFGPYTSGFRTIPFGDAEAFE
CCEECCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCEECCCCCHHHHH
AAINGNTVAALIEPIQGEAGVIIPPAGYFTRIRELCTDNNVTLILDEIQTGLGRTGKLLA
HHCCCCEEEEEEECCCCCCCEEECCCHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCHHH
EEHEGIEADVTLIGKALSGGFYPVSAVLSNSAVLGVLKPGQHGSTFGGNPLACAVARAAL
HHCCCCEEHHHHHHHHHCCCCCHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHH
KVLTEEGMIENAADMGDYFLEGLRSIRSNIVRDVRGRGLMMAVELEPEAGGARQYCHALK
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHH
ERGLLAKDTHDHTIRLAPPLVITREQVDWAVSQIEKTIS
HCCCEEECCCCCEEEECCCEEEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNTSEKLIATEQRLGAHNYKPLDVVLTRGEGVHVWDTDGNRYLDCLSAYSAVNQGHCHPK
CCCCHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEECCCCHHHHHHHHHHHHCCCCCCHH
ILAAMVEQAGRLTLTSRAFRNDQLAYLYEELAALTGSHKILPMNSGAEAVETAIKAVRKW
HHHHHHHHCCCEEEEHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHC
GYEVKGVPEGQAEIIVCADNFHGRTLSIISFSTDPDARTGFGPYTSGFRTIPFGDAEAFE
CCEECCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCEECCCCCHHHHH
AAINGNTVAALIEPIQGEAGVIIPPAGYFTRIRELCTDNNVTLILDEIQTGLGRTGKLLA
HHCCCCEEEEEEECCCCCCCEEECCCHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCHHH
EEHEGIEADVTLIGKALSGGFYPVSAVLSNSAVLGVLKPGQHGSTFGGNPLACAVARAAL
HHCCCCEEHHHHHHHHHCCCCCHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHH
KVLTEEGMIENAADMGDYFLEGLRSIRSNIVRDVRGRGLMMAVELEPEAGGARQYCHALK
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHH
ERGLLAKDTHDHTIRLAPPLVITREQVDWAVSQIEKTIS
HCCCEEECCCCCEEEECCCEEEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]