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The map label for this gene is dacC [H]

Identifier: 209551182

GI number: 209551182

Start: 3731594

End: 3732727

Strand: Reverse

Name: dacC [H]

Synonym: Rleg2_3608

Alternate gene names: 209551182

Gene position: 3732727-3731594 (Counterclockwise)

Preceding gene: 209551186

Following gene: 209551181

Centisome position: 82.26

GC content: 63.58

Gene sequence:

>1134_bases
GTGTCGACGAGCCACTTCCGTTTGTTTGCCGCCTTGCGGCCGCTGAGTTTCGCGGCCGCCGCGACGGCTGGTTTTCTTGC
CTCGGTTCCGCTCGCCGCGGCCAATCCGCATATTCTCGTCGATGTGCAGACCGGCCGTGTGCTCGAGCATGAAGAAGCTT
TCCGCAAATGGTATCCGGCCTCGCTGACCAAGCTGATGACCGTCTATACCGTGTTCGATGCGATCCGGGCCGGGCAGATC
AGCCTCGATACGCCTGTCGTCATGAGCAAGCGCGCCGCCGCGCAGCCGGCCGCCAAGATGTATTTCAAGCCGGGCCAGAA
GCTGACGCTCGACAGCGCGCTGAAGATCCTGATGGTGAAATCGGCCAATGACATCGCCGTTGCTGTCGCCGAAGCCATTG
GCGGCACGCAGGAAGGCTTCGTGACGCGGATGAACGGCGAGGCGCTGAAGCTCGGCATGACGGATTCGCATTTCGTCAAC
CCGAACGGCCTGCCGGGCAAGGGGCAGTATACGACGGCGCGCGATCTTGCGGTGCTGACCGTGGCGCTGCGCCGCGATTT
TCCGCAATATGCCTCTTATTTCGCGCTTGAGGGTTTCACCAACGGCCAGCAGAACGTGCCGAGCCTCAACATGCTGATCG
GCCGCTTCGCCGGTGCCGACGGCATGAAGACCGGCTTCATCTGCGCCTCGGGCTTCAACCAGATCGGTTCGGCGACACGC
AACGGCCGCACCATAGTCTCGGTCGTGCTCGGCACCGACAGCCTTGCGGCGCGCGCCGATGCGACGGCGAACCTTTTGCA
GAAGGGTTTCACCACCCAGTTTCCCGGCAATGAAACGCTGGGTTCGCTGCGGCCCTACGGGCAGGGACAGGACCAGGTGA
CCGACATCTCCGCCGATATCTGCAGCGCCAAGGGCGCCAAGATACGCAGCGAAACGCGCGACGAAGTCGGCCGCATGCGG
GTGCAATCGCCCTATATCCTGGAAATGGATCACGATCCGCGCTTCGTCTTTGCCGGCCTCATTCCCGGTCAGGATCCGCA
GCCGGCGGCACAGCCGGAAAAGGTGGCGACCGGCGATACGGCGGGCGGCATCGCCAACGTGCCGGTGCCGATGCCGCGCC
CGACATCTTTCTAA

Upstream 100 bases:

>100_bases
CCTGTGGAAATTACTTAGTCAATGACCTTTGCCATGTCATAGCCATATAGGCTAAATAGGGGAAGGTTTCGAGATTTTCC
TGATATCCGAAGGACAAAGC

Downstream 100 bases:

>100_bases
GATAAGTTTCAAGGTCAAACGACATGAGCGCGCTCAACGACAGGATTCCGGTCACCATCCTGACCGGCTTTCTCGGCGCC
GGCAAATCGACGCTGCTCAA

Product: serine-type D-Ala-D-Ala carboxypeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MSTSHFRLFAALRPLSFAAAATAGFLASVPLAAANPHILVDVQTGRVLEHEEAFRKWYPASLTKLMTVYTVFDAIRAGQI
SLDTPVVMSKRAAAQPAAKMYFKPGQKLTLDSALKILMVKSANDIAVAVAEAIGGTQEGFVTRMNGEALKLGMTDSHFVN
PNGLPGKGQYTTARDLAVLTVALRRDFPQYASYFALEGFTNGQQNVPSLNMLIGRFAGADGMKTGFICASGFNQIGSATR
NGRTIVSVVLGTDSLAARADATANLLQKGFTTQFPGNETLGSLRPYGQGQDQVTDISADICSAKGAKIRSETRDEVGRMR
VQSPYILEMDHDPRFVFAGLIPGQDPQPAAQPEKVATGDTAGGIANVPVPMPRPTSF

Sequences:

>Translated_377_residues
MSTSHFRLFAALRPLSFAAAATAGFLASVPLAAANPHILVDVQTGRVLEHEEAFRKWYPASLTKLMTVYTVFDAIRAGQI
SLDTPVVMSKRAAAQPAAKMYFKPGQKLTLDSALKILMVKSANDIAVAVAEAIGGTQEGFVTRMNGEALKLGMTDSHFVN
PNGLPGKGQYTTARDLAVLTVALRRDFPQYASYFALEGFTNGQQNVPSLNMLIGRFAGADGMKTGFICASGFNQIGSATR
NGRTIVSVVLGTDSLAARADATANLLQKGFTTQFPGNETLGSLRPYGQGQDQVTDISADICSAKGAKIRSETRDEVGRMR
VQSPYILEMDHDPRFVFAGLIPGQDPQPAAQPEKVATGDTAGGIANVPVPMPRPTSF
>Mature_376_residues
STSHFRLFAALRPLSFAAAATAGFLASVPLAAANPHILVDVQTGRVLEHEEAFRKWYPASLTKLMTVYTVFDAIRAGQIS
LDTPVVMSKRAAAQPAAKMYFKPGQKLTLDSALKILMVKSANDIAVAVAEAIGGTQEGFVTRMNGEALKLGMTDSHFVNP
NGLPGKGQYTTARDLAVLTVALRRDFPQYASYFALEGFTNGQQNVPSLNMLIGRFAGADGMKTGFICASGFNQIGSATRN
GRTIVSVVLGTDSLAARADATANLLQKGFTTQFPGNETLGSLRPYGQGQDQVTDISADICSAKGAKIRSETRDEVGRMRV
QSPYILEMDHDPRFVFAGLIPGQDPQPAAQPEKVATGDTAGGIANVPVPMPRPTSF

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=270, Percent_Identity=37.4074074074074, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI87082022, Length=275, Percent_Identity=35.6363636363636, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1786851, Length=249, Percent_Identity=34.136546184739, Blast_Score=138, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 40146; Mature: 40015

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSHFRLFAALRPLSFAAAATAGFLASVPLAAANPHILVDVQTGRVLEHEEAFRKWYPA
CCCCCEEHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCH
SLTKLMTVYTVFDAIRAGQISLDTPVVMSKRAAAQPAAKMYFKPGQKLTLDSALKILMVK
HHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHCCCHHHHHCCCCCEEEHHHHEEEEEEE
SANDIAVAVAEAIGGTQEGFVTRMNGEALKLGMTDSHFVNPNGLPGKGQYTTARDLAVLT
CCCCHHHHHHHHHCCCCCCEEEEECCCEEEECCCCCCEECCCCCCCCCCCCCHHHHHHHH
VALRRDFPQYASYFALEGFTNGQQNVPSLNMLIGRFAGADGMKTGFICASGFNQIGSATR
HHHHHCCHHHHHHEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEECCHHHHCCCCC
NGRTIVSVVLGTDSLAARADATANLLQKGFTTQFPGNETLGSLRPYGQGQDQVTDISADI
CCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
CSAKGAKIRSETRDEVGRMRVQSPYILEMDHDPRFVFAGLIPGQDPQPAAQPEKVATGDT
HCCCCCCHHHHHHHHHHHEECCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCC
AGGIANVPVPMPRPTSF
CCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
STSHFRLFAALRPLSFAAAATAGFLASVPLAAANPHILVDVQTGRVLEHEEAFRKWYPA
CCCCEEHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCH
SLTKLMTVYTVFDAIRAGQISLDTPVVMSKRAAAQPAAKMYFKPGQKLTLDSALKILMVK
HHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHCCCHHHHHCCCCCEEEHHHHEEEEEEE
SANDIAVAVAEAIGGTQEGFVTRMNGEALKLGMTDSHFVNPNGLPGKGQYTTARDLAVLT
CCCCHHHHHHHHHCCCCCCEEEEECCCEEEECCCCCCEECCCCCCCCCCCCCHHHHHHHH
VALRRDFPQYASYFALEGFTNGQQNVPSLNMLIGRFAGADGMKTGFICASGFNQIGSATR
HHHHHCCHHHHHHEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEECCHHHHCCCCC
NGRTIVSVVLGTDSLAARADATANLLQKGFTTQFPGNETLGSLRPYGQGQDQVTDISADI
CCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
CSAKGAKIRSETRDEVGRMRVQSPYILEMDHDPRFVFAGLIPGQDPQPAAQPEKVATGDT
HCCCCCCHHHHHHHHHHHEECCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCC
AGGIANVPVPMPRPTSF
CCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]