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The map label for this gene is yajO [H]

Identifier: 209551120

GI number: 209551120

Start: 3674869

End: 3675849

Strand: Direct

Name: yajO [H]

Synonym: Rleg2_3544

Alternate gene names: 209551120

Gene position: 3674869-3675849 (Clockwise)

Preceding gene: 209551118

Following gene: 209551122

Centisome position: 80.98

GC content: 61.37

Gene sequence:

>981_bases
ATGGAATATGCAAAATTTGGGAAGACCGGCCTCGAAGTCTCGAAAATCTGCCTCGGCTGCATGACTTTCGGCGATCCCGG
CCGCGGCAATCATACCTGGAGCCTGCGGGAAGAAGAAAGCCGGGCGATGATTAGGCAAGCGATCGACCTCGGCATCAATT
TCCTCGACACCGCCAACACCTATTCCAACGGCTCCTCGGAGGAGATCGTCGGCCGCGCCATAAAAGATTTCGCCAAGCGC
GAAGACATCGTGCTGGCAACGAAGGTGTTCAACCGCATGCGGCCGGGCCCGAATGGCGCCGGCCTGTCGCGCAAGGCGAT
CTTCGACGAAATCGACAACAGCCTGCGCCGCCTCGGCACCGACTATGTCGACCTCTACCAGATCCACCGTTTCGACTATA
CGACGCCGATCGAGGAAACGCTTGAGGCGCTGCACGACGTCGTCAAATCGGGCAAGGCGCGTTATATCGGCGCCTCCTCC
ATGTATGCTTGGCAATTTGCCAAGGCGCTCTACGTTTCCAGGCTGAACGGCTGGACAGAATTCGTCAGCATGCAGGACCA
TCTGAACCTGCTTTACCGCGAGGAAGAGCGCGAAATGCTGCCGCTCTGCGAGGATCAGAAGATCGCCGTCATCCCCTGGA
GCCCGCTTGCCCGCGGCCGCCTGACCCGCGACTGGGACGAGGCGACGGCGCGCAGCGAAACCGACGAATTCGGCAAGACG
CTTTACACCCAGTCCGTCGACGCCGACCGCAGAATAGTCGAGGCGGTGGCCGATATCGCCAAGGCCCGCGGCATCTCCCG
CGCCCAGGTCGCAACCGCTTGGATCCTGCAGAAGAGCGCCGTGACCGCCCCGATCATCGGCGCTTCCAAGCCGAACCACC
TGACCGACGCCGTTGCCTCGCTCTCGGTCAAGCTCACCACCGAAGAAGTCGCCGCATTGCAAGCACCCTATATCCCGCAC
GCCGTCGCCGGATTCAAGTAG

Upstream 100 bases:

>100_bases
CGCCGGGCGCCCTGCGACTTTGCCGGTTTCCGCACTAGATCATGGAAGGCGGTCCAGGGGCATCGGATTTGGATCAGAAA
ATTCATCGCGGAGGTATTTC

Downstream 100 bases:

>100_bases
CCTGGCCCCCAGGCATGGGCGAGGCTCTTCCTCTTTGAGCAGCGAGGGAGAGCGACACATTGTCTTTCCAGATAAAAAGC
TACTGTCGGCTGCCAGGATC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MEYAKFGKTGLEVSKICLGCMTFGDPGRGNHTWSLREEESRAMIRQAIDLGINFLDTANTYSNGSSEEIVGRAIKDFAKR
EDIVLATKVFNRMRPGPNGAGLSRKAIFDEIDNSLRRLGTDYVDLYQIHRFDYTTPIEETLEALHDVVKSGKARYIGASS
MYAWQFAKALYVSRLNGWTEFVSMQDHLNLLYREEEREMLPLCEDQKIAVIPWSPLARGRLTRDWDEATARSETDEFGKT
LYTQSVDADRRIVEAVADIAKARGISRAQVATAWILQKSAVTAPIIGASKPNHLTDAVASLSVKLTTEEVAALQAPYIPH
AVAGFK

Sequences:

>Translated_326_residues
MEYAKFGKTGLEVSKICLGCMTFGDPGRGNHTWSLREEESRAMIRQAIDLGINFLDTANTYSNGSSEEIVGRAIKDFAKR
EDIVLATKVFNRMRPGPNGAGLSRKAIFDEIDNSLRRLGTDYVDLYQIHRFDYTTPIEETLEALHDVVKSGKARYIGASS
MYAWQFAKALYVSRLNGWTEFVSMQDHLNLLYREEEREMLPLCEDQKIAVIPWSPLARGRLTRDWDEATARSETDEFGKT
LYTQSVDADRRIVEAVADIAKARGISRAQVATAWILQKSAVTAPIIGASKPNHLTDAVASLSVKLTTEEVAALQAPYIPH
AVAGFK
>Mature_326_residues
MEYAKFGKTGLEVSKICLGCMTFGDPGRGNHTWSLREEESRAMIRQAIDLGINFLDTANTYSNGSSEEIVGRAIKDFAKR
EDIVLATKVFNRMRPGPNGAGLSRKAIFDEIDNSLRRLGTDYVDLYQIHRFDYTTPIEETLEALHDVVKSGKARYIGASS
MYAWQFAKALYVSRLNGWTEFVSMQDHLNLLYREEEREMLPLCEDQKIAVIPWSPLARGRLTRDWDEATARSETDEFGKT
LYTQSVDADRRIVEAVADIAKARGISRAQVATAWILQKSAVTAPIIGASKPNHLTDAVASLSVKLTTEEVAALQAPYIPH
AVAGFK

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=313, Percent_Identity=30.6709265175719, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI4504825, Length=311, Percent_Identity=30.5466237942122, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI27436964, Length=321, Percent_Identity=28.9719626168224, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI27436962, Length=321, Percent_Identity=28.9719626168224, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI27436966, Length=321, Percent_Identity=28.6604361370716, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI27436971, Length=321, Percent_Identity=29.595015576324, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI223718702, Length=184, Percent_Identity=30.4347826086957, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI41152114, Length=184, Percent_Identity=30.9782608695652, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI41327764, Length=175, Percent_Identity=30.8571428571429, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI223718708, Length=144, Percent_Identity=31.25, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI87081735, Length=326, Percent_Identity=61.0429447852761, Blast_Score=423, Evalue=1e-120,
Organism=Escherichia coli, GI1789375, Length=326, Percent_Identity=34.6625766871166, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1788070, Length=325, Percent_Identity=31.0769230769231, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1789199, Length=351, Percent_Identity=27.9202279202279, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1788081, Length=298, Percent_Identity=32.5503355704698, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI87082198, Length=261, Percent_Identity=26.8199233716475, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI48994888, Length=314, Percent_Identity=26.4331210191083, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1786400, Length=297, Percent_Identity=24.2424242424242, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17566692, Length=320, Percent_Identity=23.4375, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17550248, Length=213, Percent_Identity=27.6995305164319, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6325169, Length=337, Percent_Identity=36.7952522255193, Blast_Score=235, Evalue=6e-63,
Organism=Saccharomyces cerevisiae, GI6323998, Length=319, Percent_Identity=31.0344827586207, Blast_Score=153, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6319958, Length=305, Percent_Identity=31.8032786885246, Blast_Score=149, Evalue=7e-37,
Organism=Saccharomyces cerevisiae, GI6319951, Length=318, Percent_Identity=28.9308176100629, Blast_Score=137, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6322615, Length=246, Percent_Identity=30.0813008130081, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6321052, Length=156, Percent_Identity=30.7692307692308, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320079, Length=266, Percent_Identity=25.5639097744361, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24646155, Length=280, Percent_Identity=31.7857142857143, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24640980, Length=330, Percent_Identity=25.4545454545455, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI45549126, Length=331, Percent_Identity=26.2839879154079, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24646159, Length=169, Percent_Identity=37.2781065088757, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24663317, Length=316, Percent_Identity=25.6329113924051, Blast_Score=82, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36386; Mature: 36386

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYAKFGKTGLEVSKICLGCMTFGDPGRGNHTWSLREEESRAMIRQAIDLGINFLDTANT
CCCHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHCCCCC
YSNGSSEEIVGRAIKDFAKREDIVLATKVFNRMRPGPNGAGLSRKAIFDEIDNSLRRLGT
CCCCCHHHHHHHHHHHHHHHCCEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCC
DYVDLYQIHRFDYTTPIEETLEALHDVVKSGKARYIGASSMYAWQFAKALYVSRLNGWTE
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHH
FVSMQDHLNLLYREEEREMLPLCEDQKIAVIPWSPLARGRLTRDWDEATARSETDEFGKT
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHCCCHHHHHHH
LYTQSVDADRRIVEAVADIAKARGISRAQVATAWILQKSAVTAPIIGASKPNHLTDAVAS
HHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHH
LSVKLTTEEVAALQAPYIPHAVAGFK
HEEEEEHHHHHHHHCCCCCCHHCCCC
>Mature Secondary Structure
MEYAKFGKTGLEVSKICLGCMTFGDPGRGNHTWSLREEESRAMIRQAIDLGINFLDTANT
CCCHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHCCCCC
YSNGSSEEIVGRAIKDFAKREDIVLATKVFNRMRPGPNGAGLSRKAIFDEIDNSLRRLGT
CCCCCHHHHHHHHHHHHHHHCCEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCC
DYVDLYQIHRFDYTTPIEETLEALHDVVKSGKARYIGASSMYAWQFAKALYVSRLNGWTE
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHH
FVSMQDHLNLLYREEEREMLPLCEDQKIAVIPWSPLARGRLTRDWDEATARSETDEFGKT
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHCCCHHHHHHH
LYTQSVDADRRIVEAVADIAKARGISRAQVATAWILQKSAVTAPIIGASKPNHLTDAVAS
HHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHH
LSVKLTTEEVAALQAPYIPHAVAGFK
HEEEEEHHHHHHHHCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]