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The map label for this gene is clpB [H]

Identifier: 209551097

GI number: 209551097

Start: 3648252

End: 3650852

Strand: Reverse

Name: clpB [H]

Synonym: Rleg2_3521

Alternate gene names: 209551097

Gene position: 3650852-3648252 (Counterclockwise)

Preceding gene: 209551098

Following gene: 209551095

Centisome position: 80.45

GC content: 62.78

Gene sequence:

>2601_bases
ATGAATATCGAGAAATATTCCGAGCGGGTGCGCGGCTTCATCCAGTCGGCGCAGACCTATGCGCTGGCGCAGGGTCATCA
GCAATTTACGCCCGAGCACGTGCTGAAAGTCCTGCTTGACGACGATCAGGGGATGGCGGCGTCGCTGATCGAGCGCGCCG
GCGGCGATGCCAAGGCTGCGCGCCTTGCCAATGACGCGGCGCTGGCCAAACTGCCGAAAATTTCCGGCGGCAACGGCAAC
ATCTATCTGGCCCAGCCGCTCGCCAAAGTGCTTTCAACCGCCGAAGAGGCGGCAAAGAAGGCCGGCGACAGCTTCGTCAC
CGTCGAGCGTCTGCTGCAGGCGCTGGCAATTGAATCCTCGGCCTCGACTTTTTCGACGCTGAAGAATTCAGGCGTGACGG
CCCAGGGTCTGAACCAGGTCATCAACGACATCCGCAAGGGCCGGACTGCGGATTCTTCCAATGCCGAGCAGGGTTTCGAT
TCACTGAAGAAGTTCGCACGCGATCTCACCGCCGAAGCTCGCGAGGGCAAGCTCGACCCGGTGATCGGCCGCGACGACGA
AATCCGCCGTACCATCCAGGTGCTTTCGCGCCGCACCAAGAACAATCCGGTGCTGATCGGCGAGCCTGGTGTGGGCAAGA
CGGCAATCGTCGAGGGGCTGGCGCTGCGCATCGTCAACGGTGACGTGCCGGAATCGCTGAAGGACAAGAAGCTGATGGCG
CTCGACATGGGCGCGCTGATTGCCGGTGCGAAATACCGCGGCGAATTCGAGGAGCGGTTGAAGGCCGTGCTCAATGAGGT
CCAGGCCGAAAACGGTGAGATCATCCTGTTCATCGATGAGATGCACACGCTGGTCGGTGCCGGCAAGGCGGACGGGGCGA
TGGACGCCTCCAATCTTCTGAAGCCCGCCCTTGCCCGCGGCGAGCTGCATTGCGTCGGCGCGACCACGCTCGACGAATAT
CGCAAACATGTCGAAAAGGATCCGGCGCTTGCCCGCCGCTTCCAGCCGGTCGTCGTCGACGAGCCGACGGTCGAGGATAC
GATCTCGATCCTGCGCGGCCTCAAGGAAAAATACGAGCAGCATCACAAGGTGCGCATCGCCGATGCGGCGCTGGTGGCGG
CGGCGACGCTTTCCAACCGCTATATCACCGACCGTTTCCTGCCCGACAAGGCGATCGACCTGATGGACGAGGCGGCGGCG
CGGCTGCGCATGCAGGTGGATTCCAAACCGGAAGAACTCGACGAACTCGATCGCCGCATTATTCAGCTGAAGATCGAGCG
CGAGGCGCTGAAGAAGGAAACCGACGTCGCCTCGGCCGACCGGCTGAAGCGGCTGGACACCGAATTGACCGGCCTCGAAG
AGGAGGCCGATGCGCTGACGGCCCGCTGGCAGGCGGAAAAGCAGAAGCTCGGCCTTGCCGCCGATCTCAAGAAGCAGCTC
GACGATGCCCGCAACGAACTGGCGATCGCCCAGCGCAAGGGTGAATTCCAGCGCGCCGGCGAGCTGACCTATGGCGTCAT
TCCGGATCTGGAAAAGCAGCTGGTCGACGCCGAAAAGCAGGATGGCGAACGCGGCGCGATGGTGCAGGAGGTTGTGATCC
CCGACAACATCGCTCATGTCGTTTCCCGCTGGACCGGTATTCCGGTCGACAGGATGCTGGAAGGCGAACGCGACAAGCTG
CTTCGGATGGAAGACGAGCTGGCGAAATCGGTGATCGGTCAGGGCGATGCGGTTCAGGCCGTGTCGCGGGCGGTGAGGCG
CGCGCGCGCCGGCCTGCAGGATCCGAACCGGCCGATCGGCTCGTTCATTTTCCTCGGCCCGACCGGCGTCGGCAAGACGG
AGCTTACCAAGGCGCTCGCCCGCTTCCTCTTCGACGATGAAACGGCGATGGTGCGCATGGACATGTCGGAATATATGGAG
AAACACTCCGTGGCCCGGCTGATCGGTGCGCCTCCCGGCTATGTCGGTTACGACGAAGGCGGAGCGCTGACGGAAGCCGT
GCGCCGCAGGCCCTATCAGGTCGTGCTGTTCGACGAGATCGAGAAGGCGCATCCTGACGTCTTCAACATCCTGCTGCAGG
TGCTGGACGATGGACGCCTGACGGATGGCCAGGGCCGGACCGTGGATTTCCGCAACACGATGATCATCATGACCTCGAAC
CTCGGCGCCGAATATCTGACGCAGCTCGCCGACGGTGACGACAGCGATACGGTTCGCGAGCAGGTGATGGAGGTCGTGCG
CGGGCATTTCCGGCCGGAATTCCTGAACCGCATCGACGAGATCATCCTCTTCCACCGCCTGAAGCGCGAGGAGATGGGCG
CGATCGTCGATATCCAGCTGAAGCGGCTGGTGGCGCTGCTCTCCGAACGGAAGATCGTCATCGATCTCGACGAGGAAGCC
CGCCACTGGCTGGCGAACAAGGGTTACGATCCGGTCTACGGCGCAAGGCCACTGAAGCGGGTGATCCAGAAATTCGTGCA
GGATCCGCTCGCCGAGCAGATCCTGTCCGGCCAGGTGCCGGACGGATCGACAGTGCGGGTGACGAATGGTTCCGATCGGC
TGCAGTTCAGGACTGGCCAGACGGTGAGCGAAGCGGCATAG

Upstream 100 bases:

>100_bases
CAAATCAGAGACGGGTGAAGCGCGGCCTGCCTCTTCAGGGGGTCGATCTCAATCATCGGTCTGCGCCTCATCAGGGCAGG
GCGATCCATGGAGGTAGAAT

Downstream 100 bases:

>100_bases
GCGGATTTTGCCCGATGAATGAGAAATGGCGGCTTCGGCCGCCATTTTTGTCTGGCGGGGACGAAATTACGCAAAGGTTA
GGGATTATTTGCTCGCCACC

Product: ATP-dependent chaperone ClpB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 866; Mature: 866

Protein sequence:

>866_residues
MNIEKYSERVRGFIQSAQTYALAQGHQQFTPEHVLKVLLDDDQGMAASLIERAGGDAKAARLANDAALAKLPKISGGNGN
IYLAQPLAKVLSTAEEAAKKAGDSFVTVERLLQALAIESSASTFSTLKNSGVTAQGLNQVINDIRKGRTADSSNAEQGFD
SLKKFARDLTAEAREGKLDPVIGRDDEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLALRIVNGDVPESLKDKKLMA
LDMGALIAGAKYRGEFEERLKAVLNEVQAENGEIILFIDEMHTLVGAGKADGAMDASNLLKPALARGELHCVGATTLDEY
RKHVEKDPALARRFQPVVVDEPTVEDTISILRGLKEKYEQHHKVRIADAALVAAATLSNRYITDRFLPDKAIDLMDEAAA
RLRMQVDSKPEELDELDRRIIQLKIEREALKKETDVASADRLKRLDTELTGLEEEADALTARWQAEKQKLGLAADLKKQL
DDARNELAIAQRKGEFQRAGELTYGVIPDLEKQLVDAEKQDGERGAMVQEVVIPDNIAHVVSRWTGIPVDRMLEGERDKL
LRMEDELAKSVIGQGDAVQAVSRAVRRARAGLQDPNRPIGSFIFLGPTGVGKTELTKALARFLFDDETAMVRMDMSEYME
KHSVARLIGAPPGYVGYDEGGALTEAVRRRPYQVVLFDEIEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTMIIMTSN
LGAEYLTQLADGDDSDTVREQVMEVVRGHFRPEFLNRIDEIILFHRLKREEMGAIVDIQLKRLVALLSERKIVIDLDEEA
RHWLANKGYDPVYGARPLKRVIQKFVQDPLAEQILSGQVPDGSTVRVTNGSDRLQFRTGQTVSEAA

Sequences:

>Translated_866_residues
MNIEKYSERVRGFIQSAQTYALAQGHQQFTPEHVLKVLLDDDQGMAASLIERAGGDAKAARLANDAALAKLPKISGGNGN
IYLAQPLAKVLSTAEEAAKKAGDSFVTVERLLQALAIESSASTFSTLKNSGVTAQGLNQVINDIRKGRTADSSNAEQGFD
SLKKFARDLTAEAREGKLDPVIGRDDEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLALRIVNGDVPESLKDKKLMA
LDMGALIAGAKYRGEFEERLKAVLNEVQAENGEIILFIDEMHTLVGAGKADGAMDASNLLKPALARGELHCVGATTLDEY
RKHVEKDPALARRFQPVVVDEPTVEDTISILRGLKEKYEQHHKVRIADAALVAAATLSNRYITDRFLPDKAIDLMDEAAA
RLRMQVDSKPEELDELDRRIIQLKIEREALKKETDVASADRLKRLDTELTGLEEEADALTARWQAEKQKLGLAADLKKQL
DDARNELAIAQRKGEFQRAGELTYGVIPDLEKQLVDAEKQDGERGAMVQEVVIPDNIAHVVSRWTGIPVDRMLEGERDKL
LRMEDELAKSVIGQGDAVQAVSRAVRRARAGLQDPNRPIGSFIFLGPTGVGKTELTKALARFLFDDETAMVRMDMSEYME
KHSVARLIGAPPGYVGYDEGGALTEAVRRRPYQVVLFDEIEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTMIIMTSN
LGAEYLTQLADGDDSDTVREQVMEVVRGHFRPEFLNRIDEIILFHRLKREEMGAIVDIQLKRLVALLSERKIVIDLDEEA
RHWLANKGYDPVYGARPLKRVIQKFVQDPLAEQILSGQVPDGSTVRVTNGSDRLQFRTGQTVSEAA
>Mature_866_residues
MNIEKYSERVRGFIQSAQTYALAQGHQQFTPEHVLKVLLDDDQGMAASLIERAGGDAKAARLANDAALAKLPKISGGNGN
IYLAQPLAKVLSTAEEAAKKAGDSFVTVERLLQALAIESSASTFSTLKNSGVTAQGLNQVINDIRKGRTADSSNAEQGFD
SLKKFARDLTAEAREGKLDPVIGRDDEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLALRIVNGDVPESLKDKKLMA
LDMGALIAGAKYRGEFEERLKAVLNEVQAENGEIILFIDEMHTLVGAGKADGAMDASNLLKPALARGELHCVGATTLDEY
RKHVEKDPALARRFQPVVVDEPTVEDTISILRGLKEKYEQHHKVRIADAALVAAATLSNRYITDRFLPDKAIDLMDEAAA
RLRMQVDSKPEELDELDRRIIQLKIEREALKKETDVASADRLKRLDTELTGLEEEADALTARWQAEKQKLGLAADLKKQL
DDARNELAIAQRKGEFQRAGELTYGVIPDLEKQLVDAEKQDGERGAMVQEVVIPDNIAHVVSRWTGIPVDRMLEGERDKL
LRMEDELAKSVIGQGDAVQAVSRAVRRARAGLQDPNRPIGSFIFLGPTGVGKTELTKALARFLFDDETAMVRMDMSEYME
KHSVARLIGAPPGYVGYDEGGALTEAVRRRPYQVVLFDEIEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTMIIMTSN
LGAEYLTQLADGDDSDTVREQVMEVVRGHFRPEFLNRIDEIILFHRLKREEMGAIVDIQLKRLVALLSERKIVIDLDEEA
RHWLANKGYDPVYGARPLKRVIQKFVQDPLAEQILSGQVPDGSTVRVTNGSDRLQFRTGQTVSEAA

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=449, Percent_Identity=33.630289532294, Blast_Score=219, Evalue=1e-56,
Organism=Escherichia coli, GI1788943, Length=854, Percent_Identity=58.5480093676815, Blast_Score=1003, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=312, Percent_Identity=47.1153846153846, Blast_Score=293, Evalue=4e-80,
Organism=Saccharomyces cerevisiae, GI6320464, Length=692, Percent_Identity=57.8034682080925, Blast_Score=810, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=859, Percent_Identity=44.3538998835856, Blast_Score=696, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 95760; Mature: 95760

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIEKYSERVRGFIQSAQTYALAQGHQQFTPEHVLKVLLDDDQGMAASLIERAGGDAKAA
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCHHHH
RLANDAALAKLPKISGGNGNIYLAQPLAKVLSTAEEAAKKAGDSFVTVERLLQALAIESS
HHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
ASTFSTLKNSGVTAQGLNQVINDIRKGRTADSSNAEQGFDSLKKFARDLTAEAREGKLDP
HHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
VIGRDDEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLALRIVNGDVPESLKDKKLMA
CCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHEEECCCCCCHHHCCHHHH
LDMGALIAGAKYRGEFEERLKAVLNEVQAENGEIILFIDEMHTLVGAGKADGAMDASNLL
HHHHHHHHCCHHCCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHCCCCCCCCCCHHHHH
KPALARGELHCVGATTLDEYRKHVEKDPALARRFQPVVVDEPTVEDTISILRGLKEKYEQ
HHHHHCCCEEEECCCHHHHHHHHHCCCHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHH
HHKVRIADAALVAAATLSNRYITDRFLPDKAIDLMDEAAARLRMQVDSKPEELDELDRRI
HCCEEHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
IQLKIEREALKKETDVASADRLKRLDTELTGLEEEADALTARWQAEKQKLGLAADLKKQL
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHH
DDARNELAIAQRKGEFQRAGELTYGVIPDLEKQLVDAEKQDGERGAMVQEVVIPDNIAHV
HHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHHHHCHHHCCCCCCCHHHHHHCCCHHHHH
VSRWTGIPVDRMLEGERDKLLRMEDELAKSVIGQGDAVQAVSRAVRRARAGLQDPNRPIG
HHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCC
SFIFLGPTGVGKTELTKALARFLFDDETAMVRMDMSEYMEKHSVARLIGAPPGYVGYDEG
CEEEECCCCCCHHHHHHHHHHHHHCCCHHEEEECHHHHHHHHHHHHHHCCCCCCCCCCCC
GALTEAVRRRPYQVVLFDEIEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTMIIMTSN
CHHHHHHHHCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECC
LGAEYLTQLADGDDSDTVREQVMEVVRGHFRPEFLNRIDEIILFHRLKREEMGAIVDIQL
CCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
KRLVALLSERKIVIDLDEEARHWLANKGYDPVYGARPLKRVIQKFVQDPLAEQILSGQVP
HHHHHHHHCCCEEEECCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHCCCCC
DGSTVRVTNGSDRLQFRTGQTVSEAA
CCCEEEEECCCCCEEEECCCCHHHCC
>Mature Secondary Structure
MNIEKYSERVRGFIQSAQTYALAQGHQQFTPEHVLKVLLDDDQGMAASLIERAGGDAKAA
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCHHHH
RLANDAALAKLPKISGGNGNIYLAQPLAKVLSTAEEAAKKAGDSFVTVERLLQALAIESS
HHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
ASTFSTLKNSGVTAQGLNQVINDIRKGRTADSSNAEQGFDSLKKFARDLTAEAREGKLDP
HHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
VIGRDDEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLALRIVNGDVPESLKDKKLMA
CCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHEEECCCCCCHHHCCHHHH
LDMGALIAGAKYRGEFEERLKAVLNEVQAENGEIILFIDEMHTLVGAGKADGAMDASNLL
HHHHHHHHCCHHCCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHCCCCCCCCCCHHHHH
KPALARGELHCVGATTLDEYRKHVEKDPALARRFQPVVVDEPTVEDTISILRGLKEKYEQ
HHHHHCCCEEEECCCHHHHHHHHHCCCHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHH
HHKVRIADAALVAAATLSNRYITDRFLPDKAIDLMDEAAARLRMQVDSKPEELDELDRRI
HCCEEHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
IQLKIEREALKKETDVASADRLKRLDTELTGLEEEADALTARWQAEKQKLGLAADLKKQL
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHH
DDARNELAIAQRKGEFQRAGELTYGVIPDLEKQLVDAEKQDGERGAMVQEVVIPDNIAHV
HHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHHHHCHHHCCCCCCCHHHHHHCCCHHHHH
VSRWTGIPVDRMLEGERDKLLRMEDELAKSVIGQGDAVQAVSRAVRRARAGLQDPNRPIG
HHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCC
SFIFLGPTGVGKTELTKALARFLFDDETAMVRMDMSEYMEKHSVARLIGAPPGYVGYDEG
CEEEECCCCCCHHHHHHHHHHHHHCCCHHEEEECHHHHHHHHHHHHHHCCCCCCCCCCCC
GALTEAVRRRPYQVVLFDEIEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTMIIMTSN
CHHHHHHHHCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECC
LGAEYLTQLADGDDSDTVREQVMEVVRGHFRPEFLNRIDEIILFHRLKREEMGAIVDIQL
CCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
KRLVALLSERKIVIDLDEEARHWLANKGYDPVYGARPLKRVIQKFVQDPLAEQILSGQVP
HHHHHHHHCCCEEEECCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHCCCCC
DGSTVRVTNGSDRLQFRTGQTVSEAA
CCCEEEEECCCCCEEEECCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]