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The map label for this gene is mdtA [H]

Identifier: 209551046

GI number: 209551046

Start: 3585946

End: 3587085

Strand: Reverse

Name: mdtA [H]

Synonym: Rleg2_3470

Alternate gene names: 209551046

Gene position: 3587085-3585946 (Counterclockwise)

Preceding gene: 209551047

Following gene: 209551045

Centisome position: 79.05

GC content: 62.89

Gene sequence:

>1140_bases
ATGTTTTCGCTCAAGACCTTTAGCCGTCGCATGCCGTCCGTTGCCCGCCTCGTGTTTGTCGGCGCCATCGGCATCGGCGT
TTCCGCCTGCTCGGAAGAGAAGGCCGAGGTCAAGCAAGTCATCCGGCCGGTAAAGGTCGTCGAGATCGCCAAGGCCGGCG
ATACCCGCAAGCTCGACTATTCCGGCTCGGTCAAGGCGCGCACGGAGATGAACCTCGGATTTCGCGTTGCCGGCAAGATC
ACCGAGCGCATGGTCGATATCGGCGACCGGGTGACGCCGGGTGATGTTCTCGCCCGTGTCGACGCCACCGATTACCAGCT
GGCGGTCAAGACGGCGGAAGCCAATCTCGCGGCGGCTGAAAGAAGCGTCGAAACCGCCGATCTTGCCAACAAACGCGCCG
AGCAGCTTTTCGACAAGAGCGTCGCTCCGAAATCGCAGCTCGAACAGGCCGCCCTCAGTCACGATCAGGCGATTTCGCAG
CGCGATGCCGCGCTCTCCGCGCTCGATCAGGCGAAGAACCAGGTGAGCTACACCGAGCTCAAGGCCGGCCAGAACGGCAT
CGTCACATCGATCAATGCCGATACCGGTCAGGTCGTCGGTTCCGGTACCGCCGTCGTCACCGTTGCCGTCGACGGCGAGA
AGGAAGTGCAGATCGCCATTCCGGAAAATGACATTGCCGAATTCAAGCCGGGGAAGACCGTCAAGACAAGCTTCTGGGCC
GACAAAAAGCTGCTGCTTGACGGCAAGGTGCGCGAGGTTTCCGGCAGCGCCGACCAGCAGTCGCGCACTTTCGCGGTGCG
CGTGAGCCTGCCGAACGATCCGCGCGTGCTGCTCGGCATGACGGCGACGATCGAGGCCGATGTCAGTACCGGCAACAGCT
ATGTCTCGATCCCGCTCAGCGCACTGGCTGAGAAAGACGGCAAGCAGATGGTCTGGACGGTCGACCGCGATACGGCGACC
GTGCATGGCCGCGACATCAAGGTCGCCGATTTCACCGGCGACGGCGTGCATGTGACCGAAGGCCTCGATACCGGCGATCT
CGTCGTCGCGGCCGGCACGCAGTTCATGAGCGAAAATCTGAAGGTGAAGGTGCCGGACCAGCAGTCGGCGCTCGCCGATA
GCGACCAGGCCGTCCGCTGA

Upstream 100 bases:

>100_bases
CGAGCGTCGACGAACTGATCGACTATGTGATCAGGGCGCTGAAGAAATAATGGACGGCAGCCGCCGTTAAGACCCCCGAA
ACGATCCAGGAGTGCGGAAG

Downstream 100 bases:

>100_bases
TCGCGCGACAAAAGGGAATAAAACCATGGACGCCAACACCACCGAAAAGCGGCCCTTCAATCTGTCGCGTTGGGCGATCG
GCCATCCGAGCATCGCCCGC

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MFSLKTFSRRMPSVARLVFVGAIGIGVSACSEEKAEVKQVIRPVKVVEIAKAGDTRKLDYSGSVKARTEMNLGFRVAGKI
TERMVDIGDRVTPGDVLARVDATDYQLAVKTAEANLAAAERSVETADLANKRAEQLFDKSVAPKSQLEQAALSHDQAISQ
RDAALSALDQAKNQVSYTELKAGQNGIVTSINADTGQVVGSGTAVVTVAVDGEKEVQIAIPENDIAEFKPGKTVKTSFWA
DKKLLLDGKVREVSGSADQQSRTFAVRVSLPNDPRVLLGMTATIEADVSTGNSYVSIPLSALAEKDGKQMVWTVDRDTAT
VHGRDIKVADFTGDGVHVTEGLDTGDLVVAAGTQFMSENLKVKVPDQQSALADSDQAVR

Sequences:

>Translated_379_residues
MFSLKTFSRRMPSVARLVFVGAIGIGVSACSEEKAEVKQVIRPVKVVEIAKAGDTRKLDYSGSVKARTEMNLGFRVAGKI
TERMVDIGDRVTPGDVLARVDATDYQLAVKTAEANLAAAERSVETADLANKRAEQLFDKSVAPKSQLEQAALSHDQAISQ
RDAALSALDQAKNQVSYTELKAGQNGIVTSINADTGQVVGSGTAVVTVAVDGEKEVQIAIPENDIAEFKPGKTVKTSFWA
DKKLLLDGKVREVSGSADQQSRTFAVRVSLPNDPRVLLGMTATIEADVSTGNSYVSIPLSALAEKDGKQMVWTVDRDTAT
VHGRDIKVADFTGDGVHVTEGLDTGDLVVAAGTQFMSENLKVKVPDQQSALADSDQAVR
>Mature_379_residues
MFSLKTFSRRMPSVARLVFVGAIGIGVSACSEEKAEVKQVIRPVKVVEIAKAGDTRKLDYSGSVKARTEMNLGFRVAGKI
TERMVDIGDRVTPGDVLARVDATDYQLAVKTAEANLAAAERSVETADLANKRAEQLFDKSVAPKSQLEQAALSHDQAISQ
RDAALSALDQAKNQVSYTELKAGQNGIVTSINADTGQVVGSGTAVVTVAVDGEKEVQIAIPENDIAEFKPGKTVKTSFWA
DKKLLLDGKVREVSGSADQQSRTFAVRVSLPNDPRVLLGMTATIEADVSTGNSYVSIPLSALAEKDGKQMVWTVDRDTAT
VHGRDIKVADFTGDGVHVTEGLDTGDLVVAAGTQFMSENLKVKVPDQQSALADSDQAVR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=351, Percent_Identity=24.7863247863248, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87081796, Length=322, Percent_Identity=24.8447204968944, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1789929, Length=389, Percent_Identity=22.879177377892, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40378; Mature: 40378

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSLKTFSRRMPSVARLVFVGAIGIGVSACSEEKAEVKQVIRPVKVVEIAKAGDTRKLDY
CCCCHHHHHHCCHHHHHHHHHHHHCCHHHCCHHHHHHHHHHCCHHEEEEECCCCCEEECC
SGSVKARTEMNLGFRVAGKITERMVDIGDRVTPGDVLARVDATDYQLAVKTAEANLAAAE
CCCEEEEEECCCCEEEHHHHHHHHHHCCCCCCCHHHEEEECCCCEEEEEEECCCHHHHHH
RSVETADLANKRAEQLFDKSVAPKSQLEQAALSHDQAISQRDAALSALDQAKNQVSYTEL
HCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
KAGQNGIVTSINADTGQVVGSGTAVVTVAVDGEKEVQIAIPENDIAEFKPGKTVKTSFWA
HCCCCCEEEEECCCCCCEEECCEEEEEEEECCCCEEEEECCCCCHHHCCCCCEEEEEECC
DKKLLLDGKVREVSGSADQQSRTFAVRVSLPNDPRVLLGMTATIEADVSTGNSYVSIPLS
CCEEEECCCEEECCCCCCCCCCEEEEEEECCCCCEEEEEEEEEEEEECCCCCCEEEEEHH
ALAEKDGKQMVWTVDRDTATVHGRDIKVADFTGDGVHVTEGLDTGDLVVAAGTQFMSENL
HHHCCCCCEEEEEEECCCEEECCCEEEEEEECCCCEEEECCCCCCCEEEEECCHHHCCCC
KVKVPDQQSALADSDQAVR
EEECCCCHHHHCCCCCCCC
>Mature Secondary Structure
MFSLKTFSRRMPSVARLVFVGAIGIGVSACSEEKAEVKQVIRPVKVVEIAKAGDTRKLDY
CCCCHHHHHHCCHHHHHHHHHHHHCCHHHCCHHHHHHHHHHCCHHEEEEECCCCCEEECC
SGSVKARTEMNLGFRVAGKITERMVDIGDRVTPGDVLARVDATDYQLAVKTAEANLAAAE
CCCEEEEEECCCCEEEHHHHHHHHHHCCCCCCCHHHEEEECCCCEEEEEEECCCHHHHHH
RSVETADLANKRAEQLFDKSVAPKSQLEQAALSHDQAISQRDAALSALDQAKNQVSYTEL
HCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
KAGQNGIVTSINADTGQVVGSGTAVVTVAVDGEKEVQIAIPENDIAEFKPGKTVKTSFWA
HCCCCCEEEEECCCCCCEEECCEEEEEEEECCCCEEEEECCCCCHHHCCCCCEEEEEECC
DKKLLLDGKVREVSGSADQQSRTFAVRVSLPNDPRVLLGMTATIEADVSTGNSYVSIPLS
CCEEEECCCEEECCCCCCCCCCEEEEEEECCCCCEEEEEEEEEEEEECCCCCCEEEEEHH
ALAEKDGKQMVWTVDRDTATVHGRDIKVADFTGDGVHVTEGLDTGDLVVAAGTQFMSENL
HHHCCCCCEEEEEEECCCEEECCCEEEEEEECCCCEEEECCCCCCCEEEEECCHHHCCCC
KVKVPDQQSALADSDQAVR
EEECCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA