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The map label for this gene is aroE [H]

Identifier: 209551041

GI number: 209551041

Start: 3579822

End: 3580682

Strand: Direct

Name: aroE [H]

Synonym: Rleg2_3465

Alternate gene names: 209551041

Gene position: 3579822-3580682 (Clockwise)

Preceding gene: 209551040

Following gene: 209551042

Centisome position: 78.89

GC content: 59.93

Gene sequence:

>861_bases
ATGGACAATAGGAACTTCCATGTCGGGCTGATCGGCGCAGACATTCAGATGTCGAAGTCGCCGGCTCTCCATGAGACCGA
AGCATACCAGGTTGGACTGGAATATCGGTACGAGCTTCTCGATTTGGCCGAGCGTGATCTTCCTGCATCTGCGCTGCCAG
ACCTTCTCGACGAGATCGAACGCCGGGGCTTTGCGGGAAGCAACATTACGCATCCGTGCAAGCAGACCGTCATAGCTCAC
CTTACCGATCTGTCGGAAGATGCCCAGATGCTCGGCGCAGTCAACACGGTCGTGCTTCGCAACGGGAAGCGGATCGGGCA
CAACACCGATTGGTATGGCTTTTATAAGAATTTCGAGCGCGGATTACCCGATGTCGCCAAAGCACATGCGGTCCTGCTCG
GCGCTGGCGGCGCGGGGGTCGCAGTCGCGCACGCAGCCATCAAGCTCGGGATCGAGATGCTTTCGATCTTCGACCAGGAC
GCAAATCGCGCCGCCACGCTTGCCGATCAGCTCAACCAGCGCTTCTCAAAAAGCTGCGCGCAGCCGATCAGCGATGTCAG
CGCCACGCTCGCTTCGGCCGACGGGCTGATCCATGCCACGCCGACGGGTATGCGAAGCCATCCTGGCATCCCGATCGACC
CGGGATCGCTTCAATCGCGTCACTGGGTCGCTGACATCGTCTACATGCCGCTTGTGACCGAACTTCTGGCTTTGGCGGAG
AAGAAGGGCTGCAGAACGCTGCCCGGTGGTGGAATGACGGTATTCCAGGCCGCCGCCGCGTTCGAATTGTTCACGGGCGT
GCAGCCGGATGCGGAACGCATGTCGCGTCACTTCGAACAACTGTGCCGAGCTGCAGTGTGA

Upstream 100 bases:

>100_bases
GGCTGAGCCCGAGGTTTTCTTCAAGTCTCCTCAGTACGAGCGCACCAGGGCGTTTCTCGGCGAAATACTTGCCCATCACT
GATCCGGTAGAGCTATCAAA

Downstream 100 bases:

>100_bases
TCTGGAGGACATGCGATGCCGCATATCATCATCGACTATAGCCGGGGCGCTGCCGAACGCGTCGTTATCGACGAGCTGAC
CAGAGCGGTGCATCGCCGAG

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MDNRNFHVGLIGADIQMSKSPALHETEAYQVGLEYRYELLDLAERDLPASALPDLLDEIERRGFAGSNITHPCKQTVIAH
LTDLSEDAQMLGAVNTVVLRNGKRIGHNTDWYGFYKNFERGLPDVAKAHAVLLGAGGAGVAVAHAAIKLGIEMLSIFDQD
ANRAATLADQLNQRFSKSCAQPISDVSATLASADGLIHATPTGMRSHPGIPIDPGSLQSRHWVADIVYMPLVTELLALAE
KKGCRTLPGGGMTVFQAAAAFELFTGVQPDAERMSRHFEQLCRAAV

Sequences:

>Translated_286_residues
MDNRNFHVGLIGADIQMSKSPALHETEAYQVGLEYRYELLDLAERDLPASALPDLLDEIERRGFAGSNITHPCKQTVIAH
LTDLSEDAQMLGAVNTVVLRNGKRIGHNTDWYGFYKNFERGLPDVAKAHAVLLGAGGAGVAVAHAAIKLGIEMLSIFDQD
ANRAATLADQLNQRFSKSCAQPISDVSATLASADGLIHATPTGMRSHPGIPIDPGSLQSRHWVADIVYMPLVTELLALAE
KKGCRTLPGGGMTVFQAAAAFELFTGVQPDAERMSRHFEQLCRAAV
>Mature_286_residues
MDNRNFHVGLIGADIQMSKSPALHETEAYQVGLEYRYELLDLAERDLPASALPDLLDEIERRGFAGSNITHPCKQTVIAH
LTDLSEDAQMLGAVNTVVLRNGKRIGHNTDWYGFYKNFERGLPDVAKAHAVLLGAGGAGVAVAHAAIKLGIEMLSIFDQD
ANRAATLADQLNQRFSKSCAQPISDVSATLASADGLIHATPTGMRSHPGIPIDPGSLQSRHWVADIVYMPLVTELLALAE
KKGCRTLPGGGMTVFQAAAAFELFTGVQPDAERMSRHFEQLCRAAV

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=271, Percent_Identity=29.1512915129151, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1789675, Length=275, Percent_Identity=31.6363636363636, Blast_Score=96, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6320332, Length=276, Percent_Identity=25.7246376811594, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 30869; Mature: 30869

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNRNFHVGLIGADIQMSKSPALHETEAYQVGLEYRYELLDLAERDLPASALPDLLDEIE
CCCCCEEEEEEECCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
RRGFAGSNITHPCKQTVIAHLTDLSEDAQMLGAVNTVVLRNGKRIGHNTDWYGFYKNFER
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
GLPDVAKAHAVLLGAGGAGVAVAHAAIKLGIEMLSIFDQDANRAATLADQLNQRFSKSCA
CCHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
QPISDVSATLASADGLIHATPTGMRSHPGIPIDPGSLQSRHWVADIVYMPLVTELLALAE
HHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KKGCRTLPGGGMTVFQAAAAFELFTGVQPDAERMSRHFEQLCRAAV
HCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDNRNFHVGLIGADIQMSKSPALHETEAYQVGLEYRYELLDLAERDLPASALPDLLDEIE
CCCCCEEEEEEECCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
RRGFAGSNITHPCKQTVIAHLTDLSEDAQMLGAVNTVVLRNGKRIGHNTDWYGFYKNFER
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
GLPDVAKAHAVLLGAGGAGVAVAHAAIKLGIEMLSIFDQDANRAATLADQLNQRFSKSCA
CCHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
QPISDVSATLASADGLIHATPTGMRSHPGIPIDPGSLQSRHWVADIVYMPLVTELLALAE
HHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KKGCRTLPGGGMTVFQAAAAFELFTGVQPDAERMSRHFEQLCRAAV
HCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA