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The map label for this gene is exo I [H]

Identifier: 209551030

GI number: 209551030

Start: 3569716

End: 3571626

Strand: Reverse

Name: exo I [H]

Synonym: Rleg2_3454

Alternate gene names: 209551030

Gene position: 3571626-3569716 (Counterclockwise)

Preceding gene: 209551031

Following gene: 209551028

Centisome position: 78.71

GC content: 63.84

Gene sequence:

>1911_bases
ATGGCCGATTATAGTCTTGAGACAAGCTGGCGCCCGGTCGAAGGCAGCTTCGGGCGCTTGACCTTCACGCTCCACAATCT
TTCGGCCGAGCCGCTGTCCGGCTTCTCGCTTGCCTATACATCGGAGACGCGGGTTGCCGACAAGCATGTCTGCGACGGCG
CCAGCCTCAAGCGGCAGGTCGCGCATTTCCATGAGTTCCTGCCGTCCGAGCAATTGACGGTGCCGCCGGGTGGGCGCTGG
CGGTTCACTGTGGAGGGGCTGAGCCGAGAGCCGAAACATGTCACCGCTGGCGTTAAATCCGCCTATCTGACACTTGCCGA
CGGTCGTCACCTTCCCGTCGATTTCGGCGATCTCATGCTCGAAGGCCGGGATGGCGGTGTGTCGCCGCCGCTCTTGCCGC
CGGGGAAAGCCGATGAACCCTATGCGCTGCTCCCCTGGCCGCTGGCGCTCGGGCTGAAGGCGGGTGACTTGCCGGCCACC
CTCTATCCGGCCGAGAGGACGCGGCCTGATGCGATCGAGGCCCTCTCCCAGGTTCTTTCTCTTTACCAGCGCCTCTACCC
AGTCGAAGACGCGCCGTTTTCGCTGAGGGCCGTCGAAGGCGGACGGCGCATTCGTTTCGTCGCCGAATCGTCGATCGCTG
CCTTCGCCTACGAGCTGCGTTTCACCGCGCACGAGATCGTGCTTTCGAGCGCCGATGAAGCGGGGCGGCGCTACGGTCTC
ATCAGCCTGGCGCAGCTGCTGCACGGGGCCCGCGCCGATGGCGAACGATTTAAATTCCCCAATTTCGGCACGATCGCCGA
CCAGCCGCGTTATGACTGGCGCGGCTGCCATCTCGATGTGTCCCGGCAGTTCTATCCGGTCGCCGACATCCTGCGGCTGA
TCGATATTCTTGCCTGGAACAAGCTCAATATCTTTCATTGGCACCTGACCGACGACGAAGCCTGGCGGCTGGAGATCAAG
GCCTATCCAGCGCTGACGGAGATCGGCGCGCGGCGCGGGCCGGACGAGGTCCTCGTGCCACAGCTCGGCGACGGAGCGGA
AACACGCGCCGGCCATTACACGCAGGATGATATCAGGCGGATCGTTGCGCATGCCGCCTCGCTCGGTGTCGAGGTCGTGC
CGGAAATCGACATTCCCGGCCACAGCACCGCAACCTTGCTCTCGCTGCCCGAGCTCGCCGACGGGCAGGAAGCGCCGGAC
AGCTATCGCGCGGTCCAAGGTTATCCCAACAATGCGCTCAACCCTGCGGTCGAATTCACCTATGAATTTCTCGGCAAGGT
GTTCGACGAGATCGTGGCGCTGTTTCCGAGCGAGTATCTCCACATTGGCGGCGACGAGGTGGCAGAGGGCGCTTGGCTAT
CCTCCCCTCTCTGCCAGGCGCTGATGAAGCGGGAGAAGCTTGCCGGCACCGCCGAGCTGCAATCCTATTTCCTGAAACGC
ATCAAGGCGATGCTCTCGGAGCGCGGCAGGAAGCTCGCCGGCTGGAACGAGGTCTCGCATGGCGGCGGCATCGACCCCGA
CGGCACGCTGCTGATGGCCTGGGAAAAGCCCGCCGTCGGCATCGAGCTGGCGCAGCAAGGCTACGACGTGGTGATGACGC
CGGGACAGGCTTATTATCTCGACATGGCGCAGGCCGAAGCCTGGGCGGAGCCCGGTGCAGCATGGGCGGGCTATTCGCCG
CCGGAACATAGCTACACTTACGAGGCCGAGGGTGAGTTGCCGGAGGCGCTGCAGGAGAAGATGCGCGGTATCCAGGCCTG
CATCTGGACTGAAAACTTCATCTCACGCGCCTATTTCAACCGGCTGGTCTTTCCGCGTCTTCCGGCCGTCGCCGAGGCCG
CATGGACACCGTCGGGCCGGAAGGATTGGGACCGGTTCGCCGCGATCGTGCGGATGTGGCCTATGCTTTAG

Upstream 100 bases:

>100_bases
GTTCGCGCCGATTACATTGCTGCCTCGAACAGGATAAGCTGCGAAGGAATGCCGGAGACCAGCCGTGATCCCGGCCGTTC
GTTGACGGGGAGCGCGCGAT

Downstream 100 bases:

>100_bases
GAAGCAATGCTTCGGCTTTCAGCCCGAGCAGCGCTGCGCCGATCAGGCCGGGTTCGATACGGCATTGGCTGCGCACGACC
AGCGGACGGTCGAACTTGCG

Product: beta-N-acetylhexosaminidase

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 636; Mature: 635

Protein sequence:

>636_residues
MADYSLETSWRPVEGSFGRLTFTLHNLSAEPLSGFSLAYTSETRVADKHVCDGASLKRQVAHFHEFLPSEQLTVPPGGRW
RFTVEGLSREPKHVTAGVKSAYLTLADGRHLPVDFGDLMLEGRDGGVSPPLLPPGKADEPYALLPWPLALGLKAGDLPAT
LYPAERTRPDAIEALSQVLSLYQRLYPVEDAPFSLRAVEGGRRIRFVAESSIAAFAYELRFTAHEIVLSSADEAGRRYGL
ISLAQLLHGARADGERFKFPNFGTIADQPRYDWRGCHLDVSRQFYPVADILRLIDILAWNKLNIFHWHLTDDEAWRLEIK
AYPALTEIGARRGPDEVLVPQLGDGAETRAGHYTQDDIRRIVAHAASLGVEVVPEIDIPGHSTATLLSLPELADGQEAPD
SYRAVQGYPNNALNPAVEFTYEFLGKVFDEIVALFPSEYLHIGGDEVAEGAWLSSPLCQALMKREKLAGTAELQSYFLKR
IKAMLSERGRKLAGWNEVSHGGGIDPDGTLLMAWEKPAVGIELAQQGYDVVMTPGQAYYLDMAQAEAWAEPGAAWAGYSP
PEHSYTYEAEGELPEALQEKMRGIQACIWTENFISRAYFNRLVFPRLPAVAEAAWTPSGRKDWDRFAAIVRMWPML

Sequences:

>Translated_636_residues
MADYSLETSWRPVEGSFGRLTFTLHNLSAEPLSGFSLAYTSETRVADKHVCDGASLKRQVAHFHEFLPSEQLTVPPGGRW
RFTVEGLSREPKHVTAGVKSAYLTLADGRHLPVDFGDLMLEGRDGGVSPPLLPPGKADEPYALLPWPLALGLKAGDLPAT
LYPAERTRPDAIEALSQVLSLYQRLYPVEDAPFSLRAVEGGRRIRFVAESSIAAFAYELRFTAHEIVLSSADEAGRRYGL
ISLAQLLHGARADGERFKFPNFGTIADQPRYDWRGCHLDVSRQFYPVADILRLIDILAWNKLNIFHWHLTDDEAWRLEIK
AYPALTEIGARRGPDEVLVPQLGDGAETRAGHYTQDDIRRIVAHAASLGVEVVPEIDIPGHSTATLLSLPELADGQEAPD
SYRAVQGYPNNALNPAVEFTYEFLGKVFDEIVALFPSEYLHIGGDEVAEGAWLSSPLCQALMKREKLAGTAELQSYFLKR
IKAMLSERGRKLAGWNEVSHGGGIDPDGTLLMAWEKPAVGIELAQQGYDVVMTPGQAYYLDMAQAEAWAEPGAAWAGYSP
PEHSYTYEAEGELPEALQEKMRGIQACIWTENFISRAYFNRLVFPRLPAVAEAAWTPSGRKDWDRFAAIVRMWPML
>Mature_635_residues
ADYSLETSWRPVEGSFGRLTFTLHNLSAEPLSGFSLAYTSETRVADKHVCDGASLKRQVAHFHEFLPSEQLTVPPGGRWR
FTVEGLSREPKHVTAGVKSAYLTLADGRHLPVDFGDLMLEGRDGGVSPPLLPPGKADEPYALLPWPLALGLKAGDLPATL
YPAERTRPDAIEALSQVLSLYQRLYPVEDAPFSLRAVEGGRRIRFVAESSIAAFAYELRFTAHEIVLSSADEAGRRYGLI
SLAQLLHGARADGERFKFPNFGTIADQPRYDWRGCHLDVSRQFYPVADILRLIDILAWNKLNIFHWHLTDDEAWRLEIKA
YPALTEIGARRGPDEVLVPQLGDGAETRAGHYTQDDIRRIVAHAASLGVEVVPEIDIPGHSTATLLSLPELADGQEAPDS
YRAVQGYPNNALNPAVEFTYEFLGKVFDEIVALFPSEYLHIGGDEVAEGAWLSSPLCQALMKREKLAGTAELQSYFLKRI
KAMLSERGRKLAGWNEVSHGGGIDPDGTLLMAWEKPAVGIELAQQGYDVVMTPGQAYYLDMAQAEAWAEPGAAWAGYSPP
EHSYTYEAEGELPEALQEKMRGIQACIWTENFISRAYFNRLVFPRLPAVAEAAWTPSGRKDWDRFAAIVRMWPML

Specific function: Hydrolyzes rapidly p-nitrophenyl-N-acetyl-beta-D- glucosaminide (PNP-beta-GlcNAc) and 4-methylumbelliferyl-beta- GlcNAc, and slightly active on p-nitrophenyl-beta-GalNAc. Hydrolyzes aryl-N-acetyl-beta-D-glucosaminide (aryl-beta-GlcNAc), aryl-beta-GalNAc a

COG id: COG3525

COG function: function code G; N-acetyl-beta-hexosaminidase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 20 family [H]

Homologues:

Organism=Homo sapiens, GI4504373, Length=417, Percent_Identity=27.8177458033573, Blast_Score=159, Evalue=1e-38,
Organism=Homo sapiens, GI189181666, Length=418, Percent_Identity=28.7081339712919, Blast_Score=149, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI17569815, Length=425, Percent_Identity=25.4117647058824, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24653074, Length=409, Percent_Identity=27.3838630806846, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI45551090, Length=409, Percent_Identity=27.3838630806846, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI281365639, Length=406, Percent_Identity=26.8472906403941, Blast_Score=132, Evalue=9e-31,
Organism=Drosophila melanogaster, GI24657474, Length=406, Percent_Identity=26.8472906403941, Blast_Score=132, Evalue=9e-31,
Organism=Drosophila melanogaster, GI24657468, Length=406, Percent_Identity=26.8472906403941, Blast_Score=132, Evalue=9e-31,
Organism=Drosophila melanogaster, GI17647501, Length=406, Percent_Identity=26.8472906403941, Blast_Score=132, Evalue=9e-31,
Organism=Drosophila melanogaster, GI17933586, Length=429, Percent_Identity=23.3100233100233, Blast_Score=108, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR001540
- InterPro:   IPR015883
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00728 Glyco_hydro_20; PF02838 Glyco_hydro_20b [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 70547; Mature: 70415

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADYSLETSWRPVEGSFGRLTFTLHNLSAEPLSGFSLAYTSETRVADKHVCDGASLKRQV
CCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCCCHHHHHHCCCCHHHHHHH
AHFHEFLPSEQLTVPPGGRWRFTVEGLSREPKHVTAGVKSAYLTLADGRHLPVDFGDLML
HHHHHHCCCCCEECCCCCCEEEEECCCCCCCCHHHHCHHHEEEEEECCCCCCCCHHHEEE
EGRDGGVSPPLLPPGKADEPYALLPWPLALGLKAGDLPATLYPAERTRPDAIEALSQVLS
ECCCCCCCCCCCCCCCCCCCEEEECCHHHHCCCCCCCCCEECCCCCCCCHHHHHHHHHHH
LYQRLYPVEDAPFSLRAVEGGRRIRFVAESSIAAFAYELRFTAHEIVLSSADEAGRRYGL
HHHHHCCCCCCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
ISLAQLLHGARADGERFKFPNFGTIADQPRYDWRGCHLDVSRQFYPVADILRLIDILAWN
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCC
KLNIFHWHLTDDEAWRLEIKAYPALTEIGARRGPDEVLVPQLGDGAETRAGHYTQDDIRR
CEEEEEEEECCCCEEEEEEEECCCHHHHHCCCCCCCEECCCCCCCCCCCCCCCCHHHHHH
IVAHAASLGVEVVPEIDIPGHSTATLLSLPELADGQEAPDSYRAVQGYPNNALNPAVEFT
HHHHHHHCCCEEEECCCCCCCCCEEEEECCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHH
YEFLGKVFDEIVALFPSEYLHIGGDEVAEGAWLSSPLCQALMKREKLAGTAELQSYFLKR
HHHHHHHHHHHHHHCCHHHEECCCCHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
IKAMLSERGRKLAGWNEVSHGGGIDPDGTLLMAWEKPAVGIELAQQGYDVVMTPGQAYYL
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHCCCCEEECCCCEEEE
DMAQAEAWAEPGAAWAGYSPPEHSYTYEAEGELPEALQEKMRGIQACIWTENFISRAYFN
EHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLVFPRLPAVAEAAWTPSGRKDWDRFAAIVRMWPML
HHHCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ADYSLETSWRPVEGSFGRLTFTLHNLSAEPLSGFSLAYTSETRVADKHVCDGASLKRQV
CCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCCCHHHHHHCCCCHHHHHHH
AHFHEFLPSEQLTVPPGGRWRFTVEGLSREPKHVTAGVKSAYLTLADGRHLPVDFGDLML
HHHHHHCCCCCEECCCCCCEEEEECCCCCCCCHHHHCHHHEEEEEECCCCCCCCHHHEEE
EGRDGGVSPPLLPPGKADEPYALLPWPLALGLKAGDLPATLYPAERTRPDAIEALSQVLS
ECCCCCCCCCCCCCCCCCCCEEEECCHHHHCCCCCCCCCEECCCCCCCCHHHHHHHHHHH
LYQRLYPVEDAPFSLRAVEGGRRIRFVAESSIAAFAYELRFTAHEIVLSSADEAGRRYGL
HHHHHCCCCCCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
ISLAQLLHGARADGERFKFPNFGTIADQPRYDWRGCHLDVSRQFYPVADILRLIDILAWN
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCC
KLNIFHWHLTDDEAWRLEIKAYPALTEIGARRGPDEVLVPQLGDGAETRAGHYTQDDIRR
CEEEEEEEECCCCEEEEEEEECCCHHHHHCCCCCCCEECCCCCCCCCCCCCCCCHHHHHH
IVAHAASLGVEVVPEIDIPGHSTATLLSLPELADGQEAPDSYRAVQGYPNNALNPAVEFT
HHHHHHHCCCEEEECCCCCCCCCEEEEECCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHH
YEFLGKVFDEIVALFPSEYLHIGGDEVAEGAWLSSPLCQALMKREKLAGTAELQSYFLKR
HHHHHHHHHHHHHHCCHHHEECCCCHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
IKAMLSERGRKLAGWNEVSHGGGIDPDGTLLMAWEKPAVGIELAQQGYDVVMTPGQAYYL
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHCCCCEEECCCCEEEE
DMAQAEAWAEPGAAWAGYSPPEHSYTYEAEGELPEALQEKMRGIQACIWTENFISRAYFN
EHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLVFPRLPAVAEAAWTPSGRKDWDRFAAIVRMWPML
HHHCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969205 [H]