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The map label for this gene is cyaB [H]

Identifier: 209550937

GI number: 209550937

Start: 3471660

End: 3473249

Strand: Direct

Name: cyaB [H]

Synonym: Rleg2_3361

Alternate gene names: 209550937

Gene position: 3471660-3473249 (Clockwise)

Preceding gene: 209550935

Following gene: 209550938

Centisome position: 76.5

GC content: 60.44

Gene sequence:

>1590_bases
GTGATTTCCGAAACCGCCGCACGTCGGAGCGGCTACTGGCTGATTGTCGTCGTGCTGGCAATGCTCGCAGGACTGCCGCT
GGCCGTCTGGCTCGATATCAGCGATCTCTCGGGAAATACCCTGCGGCGTCAAGCACGCGACATGAGTTCATTGATATCGA
GCATCCGTTCCTATTATTCCGCCAATGTCGTCGGGCGCGTCCTGGCCGCGCATGCCAGCGGCCTGACCGAAGGCACGGTC
GTCTCCCACAACTACGCGAATATTCCTGGCGCCATCCCGCTGCCGGCGACGCTTTCCCTGGAGCTCGGCGATGTCATTAA
GGAGCAGCAGGCCAACATCACCTACCGCTTCGTCTCCGACCTGCCGTTCAAAAGCCGTGCCTCCCACGAGCTCGACGAAT
TCGAGAGCAAGGCACTCGCCGCGCTGCGCGCCAATCCGCAGCAGACGCTGAACGATCTCACCCGGGTCGGATTGACCGAT
ACCTTGCGCTTCATCACCCCCGTCGTCATGGGCCAGGCTTGTGTTGCCTGCCACAATACCCATCCCGAAAGCCCGAAGAC
CAATTGGAAAGTGGGCGATGTGCGCGGCATTCAGGAAGTCATCATCCGGCAGCCCTATGCGAGCAACGTCTTCGCCTTCA
AATACCTGCTCTGCTATTTTCTGTTCGTTGCCATCATCGGCATCAGCTTCATTCTCCTCCAGCGGCAGCAGGCGCGCGCG
ATCCATAGCGCCAACCAGGATCTGGAAACGGCAAACGAGTTCCTCGCCAGCGTTTCCCTGAAGATTTCGCGCTATCTCTC
GCCGCAGATCTACAAAAGCATCTTCAGCGGGCAGAAGGATGTCGTCGTCCATACCGAGCGCAAGCGCCTGACGATCTTCT
TCTCCGACATCAAGGATTTCACCGCCACCACCGAACGCCTGCAGCCGGAAGCGCTGACGGCGATGCTCAACGAATATCTG
ACTGAGATGTCGAACATTGCCCTGGAACATGGCGGCACGGTGGACAAGTTCATCGGTGACGCCATGCTGGTGTTTTTCGG
TGACCCGGAAACCAGAGGTCCGGAGGAAGACGCCAAAGCCTGTCTGCGCATGGCCGTCGACATGCAGCGCCGTCTCGGTG
AACTCAAGGACAGATGGCGCAGAAACGGCACCGAAGAGCCTTTCGTCGTCCGGATGGGGATCAACAGCGGCTACTGCAAC
GTCGGCAATTTCGGCAGCAGCGACCGCATGGACTATACGATCATCGGAGCGGAGGCCAATCTTGCAGCCCGGCTGCAATC
GATCGCCCAGGGAGGAGAAATCGTCATCAGCTACGAAACCTATGCGCTGGTGAACGAGATCGTCGACGCCCACCCGCTGC
CGCCGATCACCATGAAGGGCATCCAGCGCGAGATCGTTCCCTATGCGGTGGATGGGCTGACACTCGGTGCGGATCACAAG
AGCCGCGTGCTCAGCGAACACCTCGCCGGCCTCGACCTGCATCTGGACATGAGCCGGCTGGAACCGGCCGATCGCCTCCG
GGTCAGGGCGGCTCTCAAGGAGGCGATCGCCGCGCTTGATGAAAGCGCGCCGGAAGCAGCCGGCCGGTGA

Upstream 100 bases:

>100_bases
ACAGGGGTGACAGGCAGCTTCGATCTTGCCGGGCAGCCGGCGAAATGTTCTTGTAGCGATCGAAAATCGAATGCCTTCCA
GAGAAGAACGAGGGGTCGCC

Downstream 100 bases:

>100_bases
CCGGACAGGGGCAAGCGTGATTTTTCCACCCGCTTTCCATATGCATCTGGACTTCCTATACCCGATCTGCTATCCCGCAT
CACCAATCGCAAGGCTGCGG

Product: adenylate/guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 2; Adenylyl cyclase 2; AC2 [H]

Number of amino acids: Translated: 529; Mature: 529

Protein sequence:

>529_residues
MISETAARRSGYWLIVVVLAMLAGLPLAVWLDISDLSGNTLRRQARDMSSLISSIRSYYSANVVGRVLAAHASGLTEGTV
VSHNYANIPGAIPLPATLSLELGDVIKEQQANITYRFVSDLPFKSRASHELDEFESKALAALRANPQQTLNDLTRVGLTD
TLRFITPVVMGQACVACHNTHPESPKTNWKVGDVRGIQEVIIRQPYASNVFAFKYLLCYFLFVAIIGISFILLQRQQARA
IHSANQDLETANEFLASVSLKISRYLSPQIYKSIFSGQKDVVVHTERKRLTIFFSDIKDFTATTERLQPEALTAMLNEYL
TEMSNIALEHGGTVDKFIGDAMLVFFGDPETRGPEEDAKACLRMAVDMQRRLGELKDRWRRNGTEEPFVVRMGINSGYCN
VGNFGSSDRMDYTIIGAEANLAARLQSIAQGGEIVISYETYALVNEIVDAHPLPPITMKGIQREIVPYAVDGLTLGADHK
SRVLSEHLAGLDLHLDMSRLEPADRLRVRAALKEAIAALDESAPEAAGR

Sequences:

>Translated_529_residues
MISETAARRSGYWLIVVVLAMLAGLPLAVWLDISDLSGNTLRRQARDMSSLISSIRSYYSANVVGRVLAAHASGLTEGTV
VSHNYANIPGAIPLPATLSLELGDVIKEQQANITYRFVSDLPFKSRASHELDEFESKALAALRANPQQTLNDLTRVGLTD
TLRFITPVVMGQACVACHNTHPESPKTNWKVGDVRGIQEVIIRQPYASNVFAFKYLLCYFLFVAIIGISFILLQRQQARA
IHSANQDLETANEFLASVSLKISRYLSPQIYKSIFSGQKDVVVHTERKRLTIFFSDIKDFTATTERLQPEALTAMLNEYL
TEMSNIALEHGGTVDKFIGDAMLVFFGDPETRGPEEDAKACLRMAVDMQRRLGELKDRWRRNGTEEPFVVRMGINSGYCN
VGNFGSSDRMDYTIIGAEANLAARLQSIAQGGEIVISYETYALVNEIVDAHPLPPITMKGIQREIVPYAVDGLTLGADHK
SRVLSEHLAGLDLHLDMSRLEPADRLRVRAALKEAIAALDESAPEAAGR
>Mature_529_residues
MISETAARRSGYWLIVVVLAMLAGLPLAVWLDISDLSGNTLRRQARDMSSLISSIRSYYSANVVGRVLAAHASGLTEGTV
VSHNYANIPGAIPLPATLSLELGDVIKEQQANITYRFVSDLPFKSRASHELDEFESKALAALRANPQQTLNDLTRVGLTD
TLRFITPVVMGQACVACHNTHPESPKTNWKVGDVRGIQEVIIRQPYASNVFAFKYLLCYFLFVAIIGISFILLQRQQARA
IHSANQDLETANEFLASVSLKISRYLSPQIYKSIFSGQKDVVVHTERKRLTIFFSDIKDFTATTERLQPEALTAMLNEYL
TEMSNIALEHGGTVDKFIGDAMLVFFGDPETRGPEEDAKACLRMAVDMQRRLGELKDRWRRNGTEEPFVVRMGINSGYCN
VGNFGSSDRMDYTIIGAEANLAARLQSIAQGGEIVISYETYALVNEIVDAHPLPPITMKGIQREIVPYAVDGLTLGADHK
SRVLSEHLAGLDLHLDMSRLEPADRLRVRAALKEAIAALDESAPEAAGR

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Drosophila melanogaster, GI221330468, Length=168, Percent_Identity=30.3571428571429, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI221330470, Length=168, Percent_Identity=30.3571428571429, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00072 Response_reg [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 58430; Mature: 58430

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISETAARRSGYWLIVVVLAMLAGLPLAVWLDISDLSGNTLRRQARDMSSLISSIRSYYS
CCCCHHHHCCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
ANVVGRVLAAHASGLTEGTVVSHNYANIPGAIPLPATLSLELGDVIKEQQANITYRFVSD
HHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCEEEEHHHHHHHHHHCCEEEEEECC
LPFKSRASHELDEFESKALAALRANPQQTLNDLTRVGLTDTLRFITPVVMGQACVACHNT
CCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCC
HPESPKTNWKVGDVRGIQEVIIRQPYASNVFAFKYLLCYFLFVAIIGISFILLQRQQARA
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IHSANQDLETANEFLASVSLKISRYLSPQIYKSIFSGQKDVVVHTERKRLTIFFSDIKDF
HHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEECCCEEEEEEHHHHHH
TATTERLQPEALTAMLNEYLTEMSNIALEHGGTVDKFIGDAMLVFFGDPETRGPEEDAKA
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCEEEEEECCCCCCCCHHHHHH
CLRMAVDMQRRLGELKDRWRRNGTEEPFVVRMGINSGYCNVGNFGSSDRMDYTIIGAEAN
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCH
LAARLQSIAQGGEIVISYETYALVNEIVDAHPLPPITMKGIQREIVPYAVDGLTLGADHK
HHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHCCEEECCEEECCCHH
SRVLSEHLAGLDLHLDMSRLEPADRLRVRAALKEAIAALDESAPEAAGR
HHHHHHHHCCCEEEEEHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MISETAARRSGYWLIVVVLAMLAGLPLAVWLDISDLSGNTLRRQARDMSSLISSIRSYYS
CCCCHHHHCCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
ANVVGRVLAAHASGLTEGTVVSHNYANIPGAIPLPATLSLELGDVIKEQQANITYRFVSD
HHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCEEEEHHHHHHHHHHCCEEEEEECC
LPFKSRASHELDEFESKALAALRANPQQTLNDLTRVGLTDTLRFITPVVMGQACVACHNT
CCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCC
HPESPKTNWKVGDVRGIQEVIIRQPYASNVFAFKYLLCYFLFVAIIGISFILLQRQQARA
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IHSANQDLETANEFLASVSLKISRYLSPQIYKSIFSGQKDVVVHTERKRLTIFFSDIKDF
HHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEECCCEEEEEEHHHHHH
TATTERLQPEALTAMLNEYLTEMSNIALEHGGTVDKFIGDAMLVFFGDPETRGPEEDAKA
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCEEEEEECCCCCCCCHHHHHH
CLRMAVDMQRRLGELKDRWRRNGTEEPFVVRMGINSGYCNVGNFGSSDRMDYTIIGAEAN
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCH
LAARLQSIAQGGEIVISYETYALVNEIVDAHPLPPITMKGIQREIVPYAVDGLTLGADHK
HHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHCCEEECCEEECCCHH
SRVLSEHLAGLDLHLDMSRLEPADRLRVRAALKEAIAALDESAPEAAGR
HHHHHHHHCCCEEEEEHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9523018; 8418825 [H]