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The map label for this gene is cya3 [H]

Identifier: 209550916

GI number: 209550916

Start: 3438177

End: 3440045

Strand: Direct

Name: cya3 [H]

Synonym: Rleg2_3340

Alternate gene names: 209550916

Gene position: 3438177-3440045 (Clockwise)

Preceding gene: 209550913

Following gene: 209550917

Centisome position: 75.77

GC content: 61.05

Gene sequence:

>1869_bases
ATGGAACGACGACTGAGCGCTATTCTCGCTGCGGATGTCGTTGGCTATAGCCGACTGATGGGCATTGATGAGGCCGGCAC
GCTGCAGGCGCTGAACCGCCACCGCTGCGAACTGGTCGATATCAGGATTTCAGACTATAAGGGCCGGATCGTCAAACTCA
CCGGCGACGGCATCCTTGCCGAATTCCAGAGCGTGGTGAACGCGGTTGCCTGCGCCGCCGAAATCCAGCGCAGCATGGCC
GCCCGCAACGAGAACGTGCCCAAGGACGAGCGCGTCGAATTCCGTATCGGCATCAATCTCGGCGACGTCGTGGTCGAGAA
CGGCGATATCTTCGGAGACGGCGTCAATCTTGCCGCCAGGCTTGAGCGTATCGCAGCGCCCGGCGGCATCGCCGTATCGG
CCTCGGTGCGCGATCAGGTCGACGCGCGCCTCAATCTCGGTTTCGAATTCATCGGCGAGCATATGCTGAAGAACATCCGG
CAGCCGGTTCAGGTCTACACCGTCACCCTGGCGCCGCCCTCCTCGGCGAAATTGGTCGCGCAGAACCGCAATACCTGCTT
CATTGCCGTGCTGCCCTTTACCAATATGAGCGGCGATGCCGACCAGGACTATTTCTCCGACGGCATCACCGAAGACATCA
TCACCGATCTCTCCAAGATCTCCAGCCTGCACGTCGTGCCGCGCAATACGATTTTCACCTATAAGGGCATATCGGTGAAG
GTGAAGCGGCTCGCTCAGGAACTTGGCGTGCGCTACGTGCTCGAGGGCAGTGTGCGCATCTTCGGCAATCGTGTGCGCAT
TTCCGGCCAGCTGATCGACACCGCCAATGGCGATCATCTCTGGGCCGAACGTTATGACCGCGACCTGACCGACATCTTCG
CCATCCAGGACGAGATCACCCATGCGATCGTCGGCCAGTTGAAGGTGCGGCTGCTGCCGGAAGAGAAGAAGGCGATCGCC
ACTGAGCCGACCGCCAATGTCGAGGCCTATACCTATTATCTCCGGGGTCGTCAGCTCTCTCACACCTGGACCAAATCCTA
TCTCCAGCTCGCAAGGCGCATGTTCTGCAAGGCGGTCGAGCTCGACCCCGACTATGCCCGCGCCTACGCCGGCATTGCCG
ATTGCGACGCGGCGATCCGCGATTGGGCACCTGACGACGTTCCGCTAAGGCGCATCCTCGAGATGAGCGCCCGCGCGCTT
GCGCTTGATCCAGACCTTCCCGAAGCCCACGCCTCCCACGGTCTTGCCCTGCATCAGAGCGGCTTTGATGACAGGGCAGC
GGCGGCCTTCGAACGGGCCCTGTCGCTCGACCCGAACCTGTTCGAGGCGAATTTCCATTATGCCCGCTTCTTCTTCATGC
ACGGCAACTTCGCTGAATCGGTTCAATATTTTACCCGCGCCGCCGCAATCCGCCCTGACGACTACGTCTCGCCGATCCAT
CTGATGTCCGCCTACCGCTCGCTCGGGCGTGTGTTGGATACGGAAAACTGGGCGCGTCTCGGTCTGCTGCGCGCCGAACG
CGCCCTGAACCTCAATCCGGAAAATTCCGGCCCGGCCCATCGCGGCGCGCTGGCGCTTGCGCATATGGGCGATACCAAGA
GGGCACGCGACTGGGCCGCCCGCGCCATCGCTATCGATCCCGACGACATCGTCGCGCAGTACAATCTCGCCTGCGTCTAT
TCCGTCCTTGGTGATATCGACCAGGCGATCGACCTTCTTGAGAGGCTGCTGCCGCACAGCTCCGTCTATCATATCAAATG
GTTCAACAATGATTCCGATCTCGACAACATCCGCGACGATCCCCGCTTCCGCAGGCTGCTGGCCGCCGCAATGATGCAGC
GCGAACGGATCGAAAGGACCGGGAGTTGA

Upstream 100 bases:

>100_bases
AAACGTCGAATCCGCCCGAATTTCTATTCCGGGGGCGACTCTACGCGACAAAAACTCTATAAAAAGCTGGACTAAACTGG
GAAGATCCATGGGAGGGGTC

Downstream 100 bases:

>100_bases
CACCGGGCTTTTCCTTCACCCAATCTTTAAAATCGCTGTGACATCGCTCCCCCACCTCTGTAATCTCCCTTGGAAAACAG
GGGACATCCGTGCGCATCCT

Product: adenylate/guanylate cyclase with TPR repeats

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 3; Adenylyl cyclase 3 [H]

Number of amino acids: Translated: 622; Mature: 622

Protein sequence:

>622_residues
MERRLSAILAADVVGYSRLMGIDEAGTLQALNRHRCELVDIRISDYKGRIVKLTGDGILAEFQSVVNAVACAAEIQRSMA
ARNENVPKDERVEFRIGINLGDVVVENGDIFGDGVNLAARLERIAAPGGIAVSASVRDQVDARLNLGFEFIGEHMLKNIR
QPVQVYTVTLAPPSSAKLVAQNRNTCFIAVLPFTNMSGDADQDYFSDGITEDIITDLSKISSLHVVPRNTIFTYKGISVK
VKRLAQELGVRYVLEGSVRIFGNRVRISGQLIDTANGDHLWAERYDRDLTDIFAIQDEITHAIVGQLKVRLLPEEKKAIA
TEPTANVEAYTYYLRGRQLSHTWTKSYLQLARRMFCKAVELDPDYARAYAGIADCDAAIRDWAPDDVPLRRILEMSARAL
ALDPDLPEAHASHGLALHQSGFDDRAAAAFERALSLDPNLFEANFHYARFFFMHGNFAESVQYFTRAAAIRPDDYVSPIH
LMSAYRSLGRVLDTENWARLGLLRAERALNLNPENSGPAHRGALALAHMGDTKRARDWAARAIAIDPDDIVAQYNLACVY
SVLGDIDQAIDLLERLLPHSSVYHIKWFNNDSDLDNIRDDPRFRRLLAAAMMQRERIERTGS

Sequences:

>Translated_622_residues
MERRLSAILAADVVGYSRLMGIDEAGTLQALNRHRCELVDIRISDYKGRIVKLTGDGILAEFQSVVNAVACAAEIQRSMA
ARNENVPKDERVEFRIGINLGDVVVENGDIFGDGVNLAARLERIAAPGGIAVSASVRDQVDARLNLGFEFIGEHMLKNIR
QPVQVYTVTLAPPSSAKLVAQNRNTCFIAVLPFTNMSGDADQDYFSDGITEDIITDLSKISSLHVVPRNTIFTYKGISVK
VKRLAQELGVRYVLEGSVRIFGNRVRISGQLIDTANGDHLWAERYDRDLTDIFAIQDEITHAIVGQLKVRLLPEEKKAIA
TEPTANVEAYTYYLRGRQLSHTWTKSYLQLARRMFCKAVELDPDYARAYAGIADCDAAIRDWAPDDVPLRRILEMSARAL
ALDPDLPEAHASHGLALHQSGFDDRAAAAFERALSLDPNLFEANFHYARFFFMHGNFAESVQYFTRAAAIRPDDYVSPIH
LMSAYRSLGRVLDTENWARLGLLRAERALNLNPENSGPAHRGALALAHMGDTKRARDWAARAIAIDPDDIVAQYNLACVY
SVLGDIDQAIDLLERLLPHSSVYHIKWFNNDSDLDNIRDDPRFRRLLAAAMMQRERIERTGS
>Mature_622_residues
MERRLSAILAADVVGYSRLMGIDEAGTLQALNRHRCELVDIRISDYKGRIVKLTGDGILAEFQSVVNAVACAAEIQRSMA
ARNENVPKDERVEFRIGINLGDVVVENGDIFGDGVNLAARLERIAAPGGIAVSASVRDQVDARLNLGFEFIGEHMLKNIR
QPVQVYTVTLAPPSSAKLVAQNRNTCFIAVLPFTNMSGDADQDYFSDGITEDIITDLSKISSLHVVPRNTIFTYKGISVK
VKRLAQELGVRYVLEGSVRIFGNRVRISGQLIDTANGDHLWAERYDRDLTDIFAIQDEITHAIVGQLKVRLLPEEKKAIA
TEPTANVEAYTYYLRGRQLSHTWTKSYLQLARRMFCKAVELDPDYARAYAGIADCDAAIRDWAPDDVPLRRILEMSARAL
ALDPDLPEAHASHGLALHQSGFDDRAAAAFERALSLDPNLFEANFHYARFFFMHGNFAESVQYFTRAAAIRPDDYVSPIH
LMSAYRSLGRVLDTENWARLGLLRAERALNLNPENSGPAHRGALALAHMGDTKRARDWAARAIAIDPDDIVAQYNLACVY
SVLGDIDQAIDLLERLLPHSSVYHIKWFNNDSDLDNIRDDPRFRRLLAAAMMQRERIERTGS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 5 TPR repeats [H]

Homologues:

Organism=Drosophila melanogaster, GI161076610, Length=161, Percent_Identity=33.5403726708075, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI19920486, Length=161, Percent_Identity=33.5403726708075, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00515 TPR_1 [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 69437; Mature: 69437

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION ; PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERRLSAILAADVVGYSRLMGIDEAGTLQALNRHRCELVDIRISDYKGRIVKLTGDGILA
CCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEEEEEECCCCEEEEEECCHHHH
EFQSVVNAVACAAEIQRSMAARNENVPKDERVEFRIGINLGDVVVENGDIFGDGVNLAAR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEECCCEECCCCHHHHH
LERIAAPGGIAVSASVRDQVDARLNLGFEFIGEHMLKNIRQPVQVYTVTLAPPSSAKLVA
HHHHCCCCCEEEECCHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCEEEE
QNRNTCFIAVLPFTNMSGDADQDYFSDGITEDIITDLSKISSLHVVPRNTIFTYKGISVK
ECCCEEEEEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHEEEEECCEEEEECCCHHH
VKRLAQELGVRYVLEGSVRIFGNRVRISGQLIDTANGDHLWAERYDRDLTDIFAIQDEIT
HHHHHHHCCCEEEEECCEEEEECEEEEEEEEEECCCCCCHHHHHHCCCHHHHHHHHHHHH
HAIVGQLKVRLLPEEKKAIATEPTANVEAYTYYLRGRQLSHTWTKSYLQLARRMFCKAVE
HHHHHHHHEEECCCHHHHCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHC
LDPDYARAYAGIADCDAAIRDWAPDDVPLRRILEMSARALALDPDLPEAHASHGLALHQS
CCHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEECCCCCHHHHHCCEEEECC
GFDDRAAAAFERALSLDPNLFEANFHYARFFFMHGNFAESVQYFTRAAAIRPDDYVSPIH
CCCHHHHHHHHHHHCCCCCEEECCCEEEEEEEEECCHHHHHHHHHHHHCCCCCCCCCHHH
LMSAYRSLGRVLDTENWARLGLLRAERALNLNPENSGPAHRGALALAHMGDTKRARDWAA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHCCEEEEECCCCHHHHHHHH
RAIAIDPDDIVAQYNLACVYSVLGDIDQAIDLLERLLPHSSVYHIKWFNNDSDLDNIRDD
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHCCCC
PRFRRLLAAAMMQRERIERTGS
HHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MERRLSAILAADVVGYSRLMGIDEAGTLQALNRHRCELVDIRISDYKGRIVKLTGDGILA
CCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEEEEEECCCCEEEEEECCHHHH
EFQSVVNAVACAAEIQRSMAARNENVPKDERVEFRIGINLGDVVVENGDIFGDGVNLAAR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEECCCEECCCCHHHHH
LERIAAPGGIAVSASVRDQVDARLNLGFEFIGEHMLKNIRQPVQVYTVTLAPPSSAKLVA
HHHHCCCCCEEEECCHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCEEEE
QNRNTCFIAVLPFTNMSGDADQDYFSDGITEDIITDLSKISSLHVVPRNTIFTYKGISVK
ECCCEEEEEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHEEEEECCEEEEECCCHHH
VKRLAQELGVRYVLEGSVRIFGNRVRISGQLIDTANGDHLWAERYDRDLTDIFAIQDEIT
HHHHHHHCCCEEEEECCEEEEECEEEEEEEEEECCCCCCHHHHHHCCCHHHHHHHHHHHH
HAIVGQLKVRLLPEEKKAIATEPTANVEAYTYYLRGRQLSHTWTKSYLQLARRMFCKAVE
HHHHHHHHEEECCCHHHHCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHC
LDPDYARAYAGIADCDAAIRDWAPDDVPLRRILEMSARALALDPDLPEAHASHGLALHQS
CCHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEECCCCCHHHHHCCEEEECC
GFDDRAAAAFERALSLDPNLFEANFHYARFFFMHGNFAESVQYFTRAAAIRPDDYVSPIH
CCCHHHHHHHHHHHCCCCCEEECCCEEEEEEEEECCHHHHHHHHHHHHCCCCCCCCCHHH
LMSAYRSLGRVLDTENWARLGLLRAERALNLNPENSGPAHRGALALAHMGDTKRARDWAA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHCCEEEEECCCCHHHHHHHH
RAIAIDPDDIVAQYNLACVYSVLGDIDQAIDLLERLLPHSSVYHIKWFNNDSDLDNIRDD
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHCCCC
PRFRRLLAAAMMQRERIERTGS
HHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10485295; 11481432 [H]