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The map label for this gene is pabB [H]

Identifier: 209550873

GI number: 209550873

Start: 3386360

End: 3387520

Strand: Direct

Name: pabB [H]

Synonym: Rleg2_3297

Alternate gene names: 209550873

Gene position: 3386360-3387520 (Clockwise)

Preceding gene: 209550872

Following gene: 209550874

Centisome position: 74.62

GC content: 61.93

Gene sequence:

>1161_bases
ATGACCATGTCTGACCCCTATATTCTCTTCCGCGACGACACATCAGGCCAGGTGATGCTTTTCGCCGAACCGGCGGAGAT
CATCGTCGCGCGAACGCGCGCCGAATTCTTTGCCGGCCTTGTCAGGATGGAAAAGGCCAAGGCCGAGGGCAAATGGCTCG
CCGGCTATATCGCCTACGAGGCCGGGTATCTGTTCGAGGAGAAACTCGCCTCCTTCGCTCGGGAAGATCGCGAAACCCCG
CTCCTCTCCTTCGGCGTCTTCGATGCTCCACAGCCGGACACGCATCCGCTTGCCCAGCCGAAACAGCGCCTCGAAAACGA
GGAATTCCTCACCGCCCCGAAAGCCGCCTGGGATTTCCCTATATATAAAGAGCGCTTCGACCGCCTGCATGAGCATCTGC
GGCTCGGCGATGCCTATCAGGCAAACCTCACCATGCCGGTCGAGGCCCGCTGGAGGGGCGATCCCCGTGCCGCCTTCTGG
TCGCTGATCGAACGGCAGCCGGTCAAATACGGCGCGCTCGTCGATCTCGGCGGTCCGCTCATCCTGTCGCGGTCGCCGGA
ACTGTTCTTCCGCACCGATGAAGAGGGCTGGATCGAGACCCATCCGATGAAGGGCACGGCGAAACGCGGCGCCACCGCCG
CCGAGGATGCCGAAATCGTCGAGGCCATGCGCCGCGATATCAAGACGCAGGCGGAAAACCGCATGATCGTCGATCTCTTG
CGCAACGATATCTCCCGTATCACCGAAGTCGGCACGCTCGATGTCCCGAAGCTCTTCGACATCGAGACCTATCCGACCGT
CCACCAGATGGTCAGCCATGTGCAGGCCAGACTGCGTCCCGGCCTTTCGATCCGCGACATCTTTGCCGCCCTCTTTCCCT
GCGGTTCGATCACCGGCGCACCGAAGATGCGGGCAATGGAAATCCTCCATACACTCGAGGATGCTCCCCGCGACGCCTAT
TGCGGAGCGATCGGCATGATTTCGCCGAGCGGCGCCATGCGGTTTTCCGTCGCCATCCGCACCATCACGCTTTTTAACGG
CGGCAGGGCCGTCTTCAATGTCGGCGGCGGCATCGTCTTCGATTCCACCGCCGAGGCCGAATATGAGGAATGCCTGCTCA
AGGCCCGCTTCGCCGTCGGCGACCAGTGGATTGCGCGATGA

Upstream 100 bases:

>100_bases
GCGGTCTCGGCCCACCACAGCAAAACCACAAGTTTCGCATCGCCCGGCATCGAAGAAAACAAAACCGTCGCAAGCATCGG
ATAGCCAAGCAAGATGCGGC

Downstream 100 bases:

>100_bases
TCGATTTTTCGCTGATCGAAACGCTGCGCTGGCAGCCCGGCGACGGGTTTATCCGCCTGCGGCTGCATCTTGCCCGGCTT
TCCCGCTCCGCCCGTCGCCT

Product: aminodeoxychorismate synthase

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MTMSDPYILFRDDTSGQVMLFAEPAEIIVARTRAEFFAGLVRMEKAKAEGKWLAGYIAYEAGYLFEEKLASFAREDRETP
LLSFGVFDAPQPDTHPLAQPKQRLENEEFLTAPKAAWDFPIYKERFDRLHEHLRLGDAYQANLTMPVEARWRGDPRAAFW
SLIERQPVKYGALVDLGGPLILSRSPELFFRTDEEGWIETHPMKGTAKRGATAAEDAEIVEAMRRDIKTQAENRMIVDLL
RNDISRITEVGTLDVPKLFDIETYPTVHQMVSHVQARLRPGLSIRDIFAALFPCGSITGAPKMRAMEILHTLEDAPRDAY
CGAIGMISPSGAMRFSVAIRTITLFNGGRAVFNVGGGIVFDSTAEAEYEECLLKARFAVGDQWIAR

Sequences:

>Translated_386_residues
MTMSDPYILFRDDTSGQVMLFAEPAEIIVARTRAEFFAGLVRMEKAKAEGKWLAGYIAYEAGYLFEEKLASFAREDRETP
LLSFGVFDAPQPDTHPLAQPKQRLENEEFLTAPKAAWDFPIYKERFDRLHEHLRLGDAYQANLTMPVEARWRGDPRAAFW
SLIERQPVKYGALVDLGGPLILSRSPELFFRTDEEGWIETHPMKGTAKRGATAAEDAEIVEAMRRDIKTQAENRMIVDLL
RNDISRITEVGTLDVPKLFDIETYPTVHQMVSHVQARLRPGLSIRDIFAALFPCGSITGAPKMRAMEILHTLEDAPRDAY
CGAIGMISPSGAMRFSVAIRTITLFNGGRAVFNVGGGIVFDSTAEAEYEECLLKARFAVGDQWIAR
>Mature_385_residues
TMSDPYILFRDDTSGQVMLFAEPAEIIVARTRAEFFAGLVRMEKAKAEGKWLAGYIAYEAGYLFEEKLASFAREDRETPL
LSFGVFDAPQPDTHPLAQPKQRLENEEFLTAPKAAWDFPIYKERFDRLHEHLRLGDAYQANLTMPVEARWRGDPRAAFWS
LIERQPVKYGALVDLGGPLILSRSPELFFRTDEEGWIETHPMKGTAKRGATAAEDAEIVEAMRRDIKTQAENRMIVDLLR
NDISRITEVGTLDVPKLFDIETYPTVHQMVSHVQARLRPGLSIRDIFAALFPCGSITGAPKMRAMEILHTLEDAPRDAYC
GAIGMISPSGAMRFSVAIRTITLFNGGRAVFNVGGGIVFDSTAEAEYEECLLKARFAVGDQWIAR

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=345, Percent_Identity=37.6811594202899, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1787518, Length=259, Percent_Identity=31.2741312741313, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786809, Length=215, Percent_Identity=25.5813953488372, Blast_Score=63, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320935, Length=254, Percent_Identity=37.4015748031496, Blast_Score=162, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6324361, Length=305, Percent_Identity=28.1967213114754, Blast_Score=99, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 43356; Mature: 43225

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMSDPYILFRDDTSGQVMLFAEPAEIIVARTRAEFFAGLVRMEKAKAEGKWLAGYIAYE
CCCCCCEEEEEECCCCEEEEEECCHHHEEEHHHHHHHHHHHHHHHHHCCCCEEEEEEHHH
AGYLFEEKLASFAREDRETPLLSFGVFDAPQPDTHPLAQPKQRLENEEFLTAPKAAWDFP
HCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCHHHHCCCCHHCCCCCCCCCCC
IYKERFDRLHEHLRLGDAYQANLTMPVEARWRGDPRAAFWSLIERQPVKYGALVDLGGPL
HHHHHHHHHHHHHHCCCCEECCEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEECCCCE
ILSRSPELFFRTDEEGWIETHPMKGTAKRGATAAEDAEIVEAMRRDIKTQAENRMIVDLL
EEECCCCEEEEECCCCCEEECCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHH
RNDISRITEVGTLDVPKLFDIETYPTVHQMVSHVQARLRPGLSIRDIFAALFPCGSITGA
HHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCC
PKMRAMEILHTLEDAPRDAYCGAIGMISPSGAMRFSVAIRTITLFNGGRAVFNVGGGIVF
CHHHHHHHHHHHHCCCCCHHCCEEEEECCCCCEEEEEEEEEEEEECCCEEEEECCCCEEE
DSTAEAEYEECLLKARFAVGDQWIAR
CCCCHHHHHHHHHHHHHHHCHHHHCC
>Mature Secondary Structure 
TMSDPYILFRDDTSGQVMLFAEPAEIIVARTRAEFFAGLVRMEKAKAEGKWLAGYIAYE
CCCCCEEEEEECCCCEEEEEECCHHHEEEHHHHHHHHHHHHHHHHHCCCCEEEEEEHHH
AGYLFEEKLASFAREDRETPLLSFGVFDAPQPDTHPLAQPKQRLENEEFLTAPKAAWDFP
HCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCHHHHCCCCHHCCCCCCCCCCC
IYKERFDRLHEHLRLGDAYQANLTMPVEARWRGDPRAAFWSLIERQPVKYGALVDLGGPL
HHHHHHHHHHHHHHCCCCEECCEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEECCCCE
ILSRSPELFFRTDEEGWIETHPMKGTAKRGATAAEDAEIVEAMRRDIKTQAENRMIVDLL
EEECCCCEEEEECCCCCEEECCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHH
RNDISRITEVGTLDVPKLFDIETYPTVHQMVSHVQARLRPGLSIRDIFAALFPCGSITGA
HHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCC
PKMRAMEILHTLEDAPRDAYCGAIGMISPSGAMRFSVAIRTITLFNGGRAVFNVGGGIVF
CHHHHHHHHHHHHCCCCCHHCCEEEEECCCCCEEEEEEEEEEEEECCCEEEEECCCCEEE
DSTAEAEYEECLLKARFAVGDQWIAR
CCCCHHHHHHHHHHHHHHHCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]