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The map label for this gene is gap [H]

Identifier: 209550813

GI number: 209550813

Start: 3326414

End: 3327424

Strand: Direct

Name: gap [H]

Synonym: Rleg2_3237

Alternate gene names: 209550813

Gene position: 3326414-3327424 (Clockwise)

Preceding gene: 209550812

Following gene: 209550814

Centisome position: 73.3

GC content: 62.51

Gene sequence:

>1011_bases
ATGACAGTCAAGGTTGCCATTAACGGCTTCGGCCGCATCGGCCGCAACGTTCTCCGCGCTATCGTTGAATCCGGCCGCAC
CGACATCGAGGTCGTCGCCATCAACGATCTCGGTCCGGTCGAGACCAACGCCCATCTGCTGCGCTACGACTCGATCCACG
GCCGTTTCCCTGCAACCGTGAAGGTCGAGGGTGACACGATCATCGTCGGCAACGGCAAGCCGATCAAGGTCACCGCGATC
AAGGATCCGGCAACGCTTCCGCACCGCGAACTCGGCGTCGACATCGCGATGGAATGCACCGGCATTTTCACGGCGCGCGA
CAAGGCCGCCGCTCACCTGACGGCCGGCGCCAAGCGCGTCATCGTTTCGGCGCCTGCAGACGGTGCCGACCTGACCGTCG
TTTTCGGCGTCAATCATGACCAGCTCACCAAGGAGCACATGGTCATCTCCAACGCCTCCTGCACCACCAACTGCCTGGTG
CCGGTCGTGAAGGTGCTCGATGACGCCGTCGGCATCGACCACGGCTTCATGACGACCATTCACTCCTACACCGGCGACCA
GCCGACGCTCGACACGATGCACAAGGACCTGTATCGCGCCCGCGCCGCCGCCCTCTCGATGATCCCGACCTCGACCGGCG
CTGCCAAGGCCGTCGGCCTCGTTCTGCCGCATCTGAAGGGCAAGCTCGACGGCACCTCGATCCGCGTTCCGACCCCGAAC
GTTTCGGTCGTCGACTTCAAGTTCGTCGCCAAGAAGGCAACCAGCGTCGGCGAAATCAACGAAGCCATCCAGGCTGCTGC
AAACGGCAAGCTGAAGGGCATCCTCGGCTACACCGACGAGCCGCTCGTCTCGCGTGATTTCAACCACGACAGCCACTCCT
CGATCTTCGCAAGCGATCAGACCAAGGTCATGGAAGGCAATTTCGTGCGCGTCCTGTCCTGGTACGATAACGAGTGGGGC
TTCTCCAGCCGCATGTCCGACACCGCCGTCGCTTTCGCCAAGCTCATCTGA

Upstream 100 bases:

>100_bases
CGCGGAAGCAAAGCTTTAATGAGGGCGCCTTGAGGCGCTCTCCATCTCCTCAATTCCAGGCCCTTTCTATCGGGCTCTAT
TCTATCGGGAGTGAATGAAC

Downstream 100 bases:

>100_bases
GCGCTGTTAAAGCATCGACAGACAAGCGGCCCGGGAAACCGGGCCGTTTTTTGTTGCCATGCCGCAAACGGAATCAGTCT
TCCCTGCACTGATATCTTTT

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MTVKVAINGFGRIGRNVLRAIVESGRTDIEVVAINDLGPVETNAHLLRYDSIHGRFPATVKVEGDTIIVGNGKPIKVTAI
KDPATLPHRELGVDIAMECTGIFTARDKAAAHLTAGAKRVIVSAPADGADLTVVFGVNHDQLTKEHMVISNASCTTNCLV
PVVKVLDDAVGIDHGFMTTIHSYTGDQPTLDTMHKDLYRARAAALSMIPTSTGAAKAVGLVLPHLKGKLDGTSIRVPTPN
VSVVDFKFVAKKATSVGEINEAIQAAANGKLKGILGYTDEPLVSRDFNHDSHSSIFASDQTKVMEGNFVRVLSWYDNEWG
FSSRMSDTAVAFAKLI

Sequences:

>Translated_336_residues
MTVKVAINGFGRIGRNVLRAIVESGRTDIEVVAINDLGPVETNAHLLRYDSIHGRFPATVKVEGDTIIVGNGKPIKVTAI
KDPATLPHRELGVDIAMECTGIFTARDKAAAHLTAGAKRVIVSAPADGADLTVVFGVNHDQLTKEHMVISNASCTTNCLV
PVVKVLDDAVGIDHGFMTTIHSYTGDQPTLDTMHKDLYRARAAALSMIPTSTGAAKAVGLVLPHLKGKLDGTSIRVPTPN
VSVVDFKFVAKKATSVGEINEAIQAAANGKLKGILGYTDEPLVSRDFNHDSHSSIFASDQTKVMEGNFVRVLSWYDNEWG
FSSRMSDTAVAFAKLI
>Mature_335_residues
TVKVAINGFGRIGRNVLRAIVESGRTDIEVVAINDLGPVETNAHLLRYDSIHGRFPATVKVEGDTIIVGNGKPIKVTAIK
DPATLPHRELGVDIAMECTGIFTARDKAAAHLTAGAKRVIVSAPADGADLTVVFGVNHDQLTKEHMVISNASCTTNCLVP
VVKVLDDAVGIDHGFMTTIHSYTGDQPTLDTMHKDLYRARAAALSMIPTSTGAAKAVGLVLPHLKGKLDGTSIRVPTPNV
SVVDFKFVAKKATSVGEINEAIQAAANGKLKGILGYTDEPLVSRDFNHDSHSSIFASDQTKVMEGNFVRVLSWYDNEWGF
SSRMSDTAVAFAKLI

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=327, Percent_Identity=48.0122324159021, Blast_Score=297, Evalue=1e-80,
Organism=Homo sapiens, GI7657116, Length=327, Percent_Identity=45.8715596330275, Blast_Score=280, Evalue=1e-75,
Organism=Escherichia coli, GI1789295, Length=335, Percent_Identity=49.8507462686567, Blast_Score=340, Evalue=8e-95,
Organism=Escherichia coli, GI1788079, Length=328, Percent_Identity=50.3048780487805, Blast_Score=317, Evalue=5e-88,
Organism=Caenorhabditis elegans, GI17534679, Length=331, Percent_Identity=49.8489425981873, Blast_Score=299, Evalue=2e-81,
Organism=Caenorhabditis elegans, GI17534677, Length=331, Percent_Identity=49.5468277945619, Blast_Score=298, Evalue=3e-81,
Organism=Caenorhabditis elegans, GI32566163, Length=331, Percent_Identity=49.5468277945619, Blast_Score=291, Evalue=4e-79,
Organism=Caenorhabditis elegans, GI17568413, Length=331, Percent_Identity=49.5468277945619, Blast_Score=290, Evalue=5e-79,
Organism=Saccharomyces cerevisiae, GI6321631, Length=336, Percent_Identity=49.702380952381, Blast_Score=309, Evalue=5e-85,
Organism=Saccharomyces cerevisiae, GI6322409, Length=336, Percent_Identity=48.2142857142857, Blast_Score=308, Evalue=8e-85,
Organism=Saccharomyces cerevisiae, GI6322468, Length=336, Percent_Identity=48.8095238095238, Blast_Score=305, Evalue=6e-84,
Organism=Drosophila melanogaster, GI17933600, Length=326, Percent_Identity=50.3067484662577, Blast_Score=301, Evalue=6e-82,
Organism=Drosophila melanogaster, GI18110149, Length=326, Percent_Identity=50.3067484662577, Blast_Score=301, Evalue=6e-82,
Organism=Drosophila melanogaster, GI85725000, Length=326, Percent_Identity=48.7730061349693, Blast_Score=295, Evalue=2e-80,
Organism=Drosophila melanogaster, GI22023983, Length=326, Percent_Identity=48.7730061349693, Blast_Score=295, Evalue=2e-80,
Organism=Drosophila melanogaster, GI19922412, Length=336, Percent_Identity=44.6428571428571, Blast_Score=270, Evalue=1e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35913; Mature: 35781

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVKVAINGFGRIGRNVLRAIVESGRTDIEVVAINDLGPVETNAHLLRYDSIHGRFPATV
CEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCCEEE
KVEGDTIIVGNGKPIKVTAIKDPATLPHRELGVDIAMECTGIFTARDKAAAHLTAGAKRV
EECCCEEEEECCCEEEEEEECCCCCCCHHHHCCEEEEEEEEEEEECCCHHHEEECCCEEE
IVSAPADGADLTVVFGVNHDQLTKEHMVISNASCTTNCLVPVVKVLDDAVGIDHGFMTTI
EEECCCCCCCEEEEEECCHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHH
HSYTGDQPTLDTMHKDLYRARAAALSMIPTSTGAAKAVGLVLPHLKGKLDGTSIRVPTPN
HHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCC
VSVVDFKFVAKKATSVGEINEAIQAAANGKLKGILGYTDEPLVSRDFNHDSHSSIFASDQ
CEEEEEEEHHHHHCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCEEEECCC
TKVMEGNFVRVLSWYDNEWGFSSRMSDTAVAFAKLI
CEEECCCEEEEEEEECCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
TVKVAINGFGRIGRNVLRAIVESGRTDIEVVAINDLGPVETNAHLLRYDSIHGRFPATV
EEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCCEEE
KVEGDTIIVGNGKPIKVTAIKDPATLPHRELGVDIAMECTGIFTARDKAAAHLTAGAKRV
EECCCEEEEECCCEEEEEEECCCCCCCHHHHCCEEEEEEEEEEEECCCHHHEEECCCEEE
IVSAPADGADLTVVFGVNHDQLTKEHMVISNASCTTNCLVPVVKVLDDAVGIDHGFMTTI
EEECCCCCCCEEEEEECCHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHH
HSYTGDQPTLDTMHKDLYRARAAALSMIPTSTGAAKAVGLVLPHLKGKLDGTSIRVPTPN
HHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCC
VSVVDFKFVAKKATSVGEINEAIQAAANGKLKGILGYTDEPLVSRDFNHDSHSSIFASDQ
CEEEEEEEHHHHHCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCEEEECCC
TKVMEGNFVRVLSWYDNEWGFSSRMSDTAVAFAKLI
CEEECCCEEEEEEEECCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7928974 [H]