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The map label for this gene is galE [C]

Identifier: 209550784

GI number: 209550784

Start: 3296852

End: 3297769

Strand: Direct

Name: galE [C]

Synonym: Rleg2_3208

Alternate gene names: 209550784

Gene position: 3296852-3297769 (Clockwise)

Preceding gene: 209550783

Following gene: 209550785

Centisome position: 72.65

GC content: 65.36

Gene sequence:

>918_bases
ATGAAGGTATTGGTATCCGGCGGAACGGGTCTCGTCGGCCGCTATGTCGTCGAGGAACTTCTGAGCGCCGGTTATCAGGT
GATCGTCGGCGGGCGCCGTGCGCCGCCACCCCGCCTCTTCTCCCGCCCGGTCGAGTTCGCAGCGCTTTCGCTCGATCCCG
ATAAGGATCAGATCGACATTTTCGACGACGCCTATTTTTTCGTCCACGCCGCCTTCAGCCATATTCCGGGCAAATATCGC
GGCGGCGAAGGCAACGATCCGAAGAGCTTCCACAGGTTGAACCTCGACGGCACCGTCCGGCTTTTCGACGCCGCCAAACG
CGCCGGCACGCGCCGCTGCATCTTCCTCTCCAGCCGCGCCGCCTATGGCGAACATCCTGAGGGAACCGAGCTCGCGGAAA
CGATGCTGGCCAAGGCGGAAACGCTCTACGGCCAGGTGAAGCTGGATGCCGAACGTGCGCTTGCCCACCTCTCCACCCCG
GGTTTTGCCGGCACAAGCCTGAGGTCGACCGGCATCTATGGCGACCTCTCGCCGAACAAATGGGACGGGCTTATCGCCGA
TTACCTCGCCGGCCGGCCGGTGGTTTCGCGCGCAGGAACGGAAGTTCACGGCCGCGACCTCGGGCGTGCGGTACGGCTGA
TGCTGGAGACGGAAAGCACCCGCATCTCCGGCGAGGTCTTCAACGTCTCGGACATATCAGTCGACACGCGCGACATCCTT
TCAGCCATCCGGCGCGAGACCGGCTGTCGGCACGTGCTGCCGCCCCCCGCCAACAGGGCGGCGCTCAATCCCATGAGCAC
GGCGAAAATCCGCGCGCTCGGCTGGATGCCGGGCGGAGCCCCGCTGTTCGAGGAAACGATGCAGCGGCTCGCCGCGGCGC
TGCCGGCGGCCCCGGAACACAGGTCCACGCAAGTCTGA

Upstream 100 bases:

>100_bases
AGGCGGCGCGGCTACAACCTTTGATCGATTTGTGGCACCGTTTCCACGATGGCGGCGATGTGCCTGAGATTGCGGGGCTG
GCCAATCCGGAAGGAGCAGC

Downstream 100 bases:

>100_bases
CGTTGCAGAATGCGCCGAATTGCAATCGGGGACCCGGACTGTCGGGAATTGTCCATGCAGGTCGCAACCGCCTCTGCCTC
CAATATCTTGCGCGGCACGT

Product: NAD-dependent epimerase/dehydratase

Products: UDPglucoseal [C]

Alternate protein names: Sulfolipid Biosynthesis Protein; UDP-Glucose 4-Epimerase; Sulfolipid Biosynthesis Protein SqdC; NAD Dependent Epimerase; NAD Dependent Epimerase/Dehydratase Family

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MKVLVSGGTGLVGRYVVEELLSAGYQVIVGGRRAPPPRLFSRPVEFAALSLDPDKDQIDIFDDAYFFVHAAFSHIPGKYR
GGEGNDPKSFHRLNLDGTVRLFDAAKRAGTRRCIFLSSRAAYGEHPEGTELAETMLAKAETLYGQVKLDAERALAHLSTP
GFAGTSLRSTGIYGDLSPNKWDGLIADYLAGRPVVSRAGTEVHGRDLGRAVRLMLETESTRISGEVFNVSDISVDTRDIL
SAIRRETGCRHVLPPPANRAALNPMSTAKIRALGWMPGGAPLFEETMQRLAAALPAAPEHRSTQV

Sequences:

>Translated_305_residues
MKVLVSGGTGLVGRYVVEELLSAGYQVIVGGRRAPPPRLFSRPVEFAALSLDPDKDQIDIFDDAYFFVHAAFSHIPGKYR
GGEGNDPKSFHRLNLDGTVRLFDAAKRAGTRRCIFLSSRAAYGEHPEGTELAETMLAKAETLYGQVKLDAERALAHLSTP
GFAGTSLRSTGIYGDLSPNKWDGLIADYLAGRPVVSRAGTEVHGRDLGRAVRLMLETESTRISGEVFNVSDISVDTRDIL
SAIRRETGCRHVLPPPANRAALNPMSTAKIRALGWMPGGAPLFEETMQRLAAALPAAPEHRSTQV
>Mature_305_residues
MKVLVSGGTGLVGRYVVEELLSAGYQVIVGGRRAPPPRLFSRPVEFAALSLDPDKDQIDIFDDAYFFVHAAFSHIPGKYR
GGEGNDPKSFHRLNLDGTVRLFDAAKRAGTRRCIFLSSRAAYGEHPEGTELAETMLAKAETLYGQVKLDAERALAHLSTP
GFAGTSLRSTGIYGDLSPNKWDGLIADYLAGRPVVSRAGTEVHGRDLGRAVRLMLETESTRISGEVFNVSDISVDTRDIL
SAIRRETGCRHVLPPPANRAALNPMSTAKIRALGWMPGGAPLFEETMQRLAAALPAAPEHRSTQV

Specific function: Galactose metabolism; third step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 5.1.3.2 [C]

Molecular weight: Translated: 33039; Mature: 33039

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLVSGGTGLVGRYVVEELLSAGYQVIVGGRRAPPPRLFSRPVEFAALSLDPDKDQIDI
CEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHCCCCEEEEECCCCCCCEEE
FDDAYFFVHAAFSHIPGKYRGGEGNDPKSFHRLNLDGTVRLFDAAKRAGTRRCIFLSSRA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCEEEHHHHHHHCCCEEEEEEECCC
AYGEHPEGTELAETMLAKAETLYGQVKLDAERALAHLSTPGFAGTSLRSTGIYGDLSPNK
CCCCCCCCHHHHHHHHHHHHHHHEEEEECHHHHHHHHCCCCCCCCCCCCCCCEECCCCCC
WDGLIADYLAGRPVVSRAGTEVHGRDLGRAVRLMLETESTRISGEVFNVSDISVDTRDIL
HHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCCEECCEEEECCCCCCCHHHHH
SAIRRETGCRHVLPPPANRAALNPMSTAKIRALGWMPGGAPLFEETMQRLAAALPAAPEH
HHHHHHCCCCCCCCCCCCCCCCCCCCHHHEEEEECCCCCCHHHHHHHHHHHHHCCCCCCC
RSTQV
CCCCC
>Mature Secondary Structure
MKVLVSGGTGLVGRYVVEELLSAGYQVIVGGRRAPPPRLFSRPVEFAALSLDPDKDQIDI
CEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHCCCCEEEEECCCCCCCEEE
FDDAYFFVHAAFSHIPGKYRGGEGNDPKSFHRLNLDGTVRLFDAAKRAGTRRCIFLSSRA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCEEEHHHHHHHCCCEEEEEEECCC
AYGEHPEGTELAETMLAKAETLYGQVKLDAERALAHLSTPGFAGTSLRSTGIYGDLSPNK
CCCCCCCCHHHHHHHHHHHHHHHEEEEECHHHHHHHHCCCCCCCCCCCCCCCEECCCCCC
WDGLIADYLAGRPVVSRAGTEVHGRDLGRAVRLMLETESTRISGEVFNVSDISVDTRDIL
HHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCCEECCEEEECCCCCCCHHHHH
SAIRRETGCRHVLPPPANRAALNPMSTAKIRALGWMPGGAPLFEETMQRLAAALPAAPEH
HHHHHHCCCCCCCCCCCCCCCCCCCCHHHEEEEECCCCCCHHHHHHHHHHHHHCCCCCCC
RSTQV
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NAD+ [C]

Metal ions: NA

Kcat value (1/min): 57600 [C]

Specific activity: 233.3

Km value (mM): 0.256 {UDPgalactose}} 0.225 {UDPgalactose}} 0.2 {UDPgalactose}} 0.18 {UDPgalactose}} 0.16 {UDPgalactose}} 0.14 {UDPgalactose}} 0.048 {UDPgalactose}} 0.026 {UDPgalactose}} [C]

Substrates: UDPglucose [C]

Specific reaction: UDPglucose <==> UDPglucoseal [C]

General reaction: Epimerization (specificity for carbon forming a hexosulose) [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA