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The map label for this gene is ampR [H]

Identifier: 209550523

GI number: 209550523

Start: 3003002

End: 3003880

Strand: Reverse

Name: ampR [H]

Synonym: Rleg2_2946

Alternate gene names: 209550523

Gene position: 3003880-3003002 (Counterclockwise)

Preceding gene: 209550532

Following gene: 209550520

Centisome position: 66.19

GC content: 64.73

Gene sequence:

>879_bases
ATGGTTCGGCAATTTCTCCCCTTGAACGGCCTGCGCGCCTTCGAAGCCTCGGCACGGCATCTGAGTTTCACCCGTGCGGC
GATCGAGCTCTGCGTCACCCAGGCGGCGGTCAGCCAGCAGGTCAAAGGCCTGGAGACGCGATTGGGCGTGGCGCTGTTCC
AGCGTCTTCCCCGCGGTTTGAAAATCACCGCGGAAGGCGAAGCTTTGCTGCCGACGGTGACGGCCTCCTTCGACCAGATG
GCGACGACGCTGGACAGGATCGAAGCCGGGCAGGTGCGGGAATTGCTGTTTCTCGGCGTTGTCGGCACATTTGCCGTCGG
CTGGCTGTTGCCGCGGCTTGCGGATTTCCAGCGCCGGCATCCCTTTATCGATCTCCGCATTTCCACCAACAACAATCGGG
TCGATCCGGCCGCCGAGGGGCTGGATTTCGCCATCCGCTTCGGCAGCGGTTCATGGCACGGAACGGAGGCGCAGCGCCTG
TTCGAAGCGCCGCTCTCGCCGCTCTGCATCCCCAAACTGGCGGAGCGTCTGCAGTCGCCTGAAGATCTTGCCGGGGCGGT
GCTGCTGCGCAGTTACCGGACGGATGAATGGAGCAGCTGGTTTCAGGCGGCAGGGGTTCCCCCGGCTGCGCAGGTCAATG
CCGGCATCGTCTTCGATTCCTCCGTCGGCATGATGGAGGCCGCCCTACAGGGGCTCGGCGTCGCGCTCGCGCCGCCATCG
ATGTTCACAAGGCATCTTTCCTCCGGCGCGATCGTCCAGCCCTTCGCCGCCGCCATATCGCTCGGCAGCTATTGGCTGAC
CCGCCTGCAGTCGCGGCCGGTCACGACGGCGATGCAGGCATTTTCGGACTGGATCGGTGCGCAATCGAGCGCTGTATGA

Upstream 100 bases:

>100_bases
AAACAAGCGCAAAAGCGCATGGGTACGACGTTTAACGGCGCTATTTTGCAATCACAAATGATGATATCTCGCAGCAGCCA
CAAGAATTTCTAGGGCTCGA

Downstream 100 bases:

>100_bases
TCATCGGAGCGCCCACGCGAGTGGGCGCTCCGAGCCGCATCATTGTTGGAATGCCGAGGTCACTTCTGAATGCAGGTGTC
GACGGTATCCTTGGTGCATT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MVRQFLPLNGLRAFEASARHLSFTRAAIELCVTQAAVSQQVKGLETRLGVALFQRLPRGLKITAEGEALLPTVTASFDQM
ATTLDRIEAGQVRELLFLGVVGTFAVGWLLPRLADFQRRHPFIDLRISTNNNRVDPAAEGLDFAIRFGSGSWHGTEAQRL
FEAPLSPLCIPKLAERLQSPEDLAGAVLLRSYRTDEWSSWFQAAGVPPAAQVNAGIVFDSSVGMMEAALQGLGVALAPPS
MFTRHLSSGAIVQPFAAAISLGSYWLTRLQSRPVTTAMQAFSDWIGAQSSAV

Sequences:

>Translated_292_residues
MVRQFLPLNGLRAFEASARHLSFTRAAIELCVTQAAVSQQVKGLETRLGVALFQRLPRGLKITAEGEALLPTVTASFDQM
ATTLDRIEAGQVRELLFLGVVGTFAVGWLLPRLADFQRRHPFIDLRISTNNNRVDPAAEGLDFAIRFGSGSWHGTEAQRL
FEAPLSPLCIPKLAERLQSPEDLAGAVLLRSYRTDEWSSWFQAAGVPPAAQVNAGIVFDSSVGMMEAALQGLGVALAPPS
MFTRHLSSGAIVQPFAAAISLGSYWLTRLQSRPVTTAMQAFSDWIGAQSSAV
>Mature_292_residues
MVRQFLPLNGLRAFEASARHLSFTRAAIELCVTQAAVSQQVKGLETRLGVALFQRLPRGLKITAEGEALLPTVTASFDQM
ATTLDRIEAGQVRELLFLGVVGTFAVGWLLPRLADFQRRHPFIDLRISTNNNRVDPAAEGLDFAIRFGSGSWHGTEAQRL
FEAPLSPLCIPKLAERLQSPEDLAGAVLLRSYRTDEWSSWFQAAGVPPAAQVNAGIVFDSSVGMMEAALQGLGVALAPPS
MFTRHLSSGAIVQPFAAAISLGSYWLTRLQSRPVTTAMQAFSDWIGAQSSAV

Specific function: This protein is a positive regulator of gene expression of beta-lactamase (AmpC) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789173, Length=295, Percent_Identity=36.9491525423729, Blast_Score=191, Evalue=5e-50,
Organism=Escherichia coli, GI1786448, Length=283, Percent_Identity=36.3957597173145, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1788706, Length=295, Percent_Identity=31.5254237288136, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1786401, Length=283, Percent_Identity=26.1484098939929, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI145693193, Length=305, Percent_Identity=26.5573770491803, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787128, Length=265, Percent_Identity=25.2830188679245, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1787589, Length=287, Percent_Identity=24.0418118466899, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1790262, Length=250, Percent_Identity=26.8, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI157672245, Length=140, Percent_Identity=34.2857142857143, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87081978, Length=280, Percent_Identity=26.7857142857143, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31608; Mature: 31608

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRQFLPLNGLRAFEASARHLSFTRAAIELCVTQAAVSQQVKGLETRLGVALFQRLPRGL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KITAEGEALLPTVTASFDQMATTLDRIEAGQVRELLFLGVVGTFAVGWLLPRLADFQRRH
EEEECCCEECHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PFIDLRISTNNNRVDPAAEGLDFAIRFGSGSWHGTEAQRLFEAPLSPLCIPKLAERLQSP
CEEEEEEECCCCCCCHHHCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCHHHHHHHHCCH
EDLAGAVLLRSYRTDEWSSWFQAAGVPPAAQVNAGIVFDSSVGMMEAALQGLGVALAPPS
HHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHCCCCEEECCCHHHHHHHHHHCCEEECCHH
MFTRHLSSGAIVQPFAAAISLGSYWLTRLQSRPVTTAMQAFSDWIGAQSSAV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVRQFLPLNGLRAFEASARHLSFTRAAIELCVTQAAVSQQVKGLETRLGVALFQRLPRGL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KITAEGEALLPTVTASFDQMATTLDRIEAGQVRELLFLGVVGTFAVGWLLPRLADFQRRH
EEEECCCEECHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PFIDLRISTNNNRVDPAAEGLDFAIRFGSGSWHGTEAQRLFEAPLSPLCIPKLAERLQSP
CEEEEEEECCCCCCCHHHCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCHHHHHHHHCCH
EDLAGAVLLRSYRTDEWSSWFQAAGVPPAAQVNAGIVFDSSVGMMEAALQGLGVALAPPS
HHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHCCCCEEECCCHHHHHHHHHHCCEEECCHH
MFTRHLSSGAIVQPFAAAISLGSYWLTRLQSRPVTTAMQAFSDWIGAQSSAV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8405939; 10984043; 2125210 [H]