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The map label for this gene is yedX [C]

Identifier: 209550461

GI number: 209550461

Start: 2935313

End: 2935669

Strand: Reverse

Name: yedX [C]

Synonym: Rleg2_2884

Alternate gene names: 209550461

Gene position: 2935669-2935313 (Counterclockwise)

Preceding gene: 209550462

Following gene: 209550460

Centisome position: 64.69

GC content: 61.34

Gene sequence:

>357_bases
ATGACCGGACTGACCACACATGTTCTCGATACCGCCCTGGGCAAGCCGGCCCAACGGCTGAGGATCGATCTTTTCCAGCT
CGACGGCGAGATCCGCAGACATCTGAAGACGGTCGAGACCAATGCCGACGGCCGGGTCGACGGCGGCCCCATCCTTGCCG
GCGAAAATTTTCGGGCCGGCACCTATGAACTGGTCTTCCACGCCGGCGATTATCTGAGGGCTTGCGGCACGCCGCTGCCG
CACCCGGCCTTCCTCGATCTCGTGCCGATCCGCTTCGGCATTGCCGATATCACGGCGCATTACCATGTGCCGCTGCTGAT
CTCACCCTATGGTTATTCCACCTATCGAGGCAGTTAG

Upstream 100 bases:

>100_bases
GTGAGGTCTCCGATTTCCTGGTCGTCGACCGCGACGGGGCAGGCAACAATCTGGAGGAATTCTTCTTCGAAACCCCCTAC
ATCATCAAAGAGCCAGCCCT

Downstream 100 bases:

>100_bases
GGATGCGTTTTGCCGCGATCGCCGACATTCACGGCAACCATCTGGCGCTCGAGGCGGTGCTTGCGGATATTCGCGCTGAA
GGCATCGAGGAGATCGTCAA

Product: hydroxyisourate hydrolase

Products: NA

Alternate protein names: HIU hydrolase 2; HIUHase 2 [H]

Number of amino acids: Translated: 118; Mature: 117

Protein sequence:

>118_residues
MTGLTTHVLDTALGKPAQRLRIDLFQLDGEIRRHLKTVETNADGRVDGGPILAGENFRAGTYELVFHAGDYLRACGTPLP
HPAFLDLVPIRFGIADITAHYHVPLLISPYGYSTYRGS

Sequences:

>Translated_118_residues
MTGLTTHVLDTALGKPAQRLRIDLFQLDGEIRRHLKTVETNADGRVDGGPILAGENFRAGTYELVFHAGDYLRACGTPLP
HPAFLDLVPIRFGIADITAHYHVPLLISPYGYSTYRGS
>Mature_117_residues
TGLTTHVLDTALGKPAQRLRIDLFQLDGEIRRHLKTVETNADGRVDGGPILAGENFRAGTYELVFHAGDYLRACGTPLPH
PAFLDLVPIRFGIADITAHYHVPLLISPYGYSTYRGS

Specific function: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) [H]

COG id: COG2351

COG function: function code R; Transthyretin-like protein

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788281, Length=115, Percent_Identity=36.5217391304348, Blast_Score=81, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI115532922, Length=116, Percent_Identity=36.2068965517241, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115532920, Length=116, Percent_Identity=36.2068965517241, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115534555, Length=116, Percent_Identity=37.0689655172414, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24652571, Length=119, Percent_Identity=40.3361344537815, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014306
- InterPro:   IPR000895 [H]

Pfam domain/function: PF00576 Transthyretin [H]

EC number: =3.5.2.17 [H]

Molecular weight: Translated: 12960; Mature: 12829

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS00768 TRANSTHYRETIN_1 ; PS00769 TRANSTHYRETIN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGLTTHVLDTALGKPAQRLRIDLFQLDGEIRRHLKTVETNADGRVDGGPILAGENFRAG
CCCCHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCC
TYELVFHAGDYLRACGTPLPHPAFLDLVPIRFGIADITAHYHVPLLISPYGYSTYRGS
EEEEEEECCHHHHHCCCCCCCCCHHEEHHHHHCHHHEEEEEECEEEECCCCCCCCCCC
>Mature Secondary Structure 
TGLTTHVLDTALGKPAQRLRIDLFQLDGEIRRHLKTVETNADGRVDGGPILAGENFRAG
CCCHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCC
TYELVFHAGDYLRACGTPLPHPAFLDLVPIRFGIADITAHYHVPLLISPYGYSTYRGS
EEEEEEECCHHHHHCCCCCCCCCHHEEHHHHHCHHHEEEEEECEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]