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The map label for this gene is engA [H]

Identifier: 209550425

GI number: 209550425

Start: 2896289

End: 2897710

Strand: Reverse

Name: engA [H]

Synonym: Rleg2_2846

Alternate gene names: 209550425

Gene position: 2897710-2896289 (Counterclockwise)

Preceding gene: 209550426

Following gene: 209550423

Centisome position: 63.86

GC content: 63.08

Gene sequence:

>1422_bases
ATGAGTTTCACGGTCGCGATCGTCGGTCGTCCGAATGTCGGCAAGTCGACGCTTTTCAACCGCCTGGTGGGAAAGAAGCT
GGCGCTTGTCGACGACACGCCCGGCGTGACCCGCGACCGCCGGCCGGGCGATGCGCGGCTGATGGGCCTGACCTTTACCA
TTATCGACACGGCCGGTCTGGAAGAGGCCGACGAGGAAAGCCTGCAGGGCCGGATGCGCGCTCAGACGGAAGCGGCAATC
GACGAGGCCGATCTTTCGCTTTTCGTCGTCGATGCCAAGAACGGGCTGACGCCCGTCGACACGGCTCTTGCCGAAATGCT
GCGCCGGCGCGGCAAGCCGGTGGTGCTGGTTGCCAATAAATCCGAAGCACGCGGCTCCGACAGCGGCTTCTACGACGCCT
ATACGCTCGGGCTTGGCGAGCCGACGCCGATTTCGGCCGAACACGGCGAGGGCATGCTCGATCTGCGCGACGCGATCGTC
GAGGCGATCGGCAAGGATCGGGCCTATGCCAAGGAGGATGTCGCCGTCACCAACGTCGATATTTCCGAGGCCGCGGGTGA
AGGCGAAGACGAGGACGAAGAGCCCCTCTATGACGACACCAAGCCGCTCAGGGTGGCAATCGTCGGCCGGCCGAATGCCG
GCAAGTCGACGCTGATCAACCGTTTCCTCGGCGAGGACCGGCTTTTGACCGGGCCGGAGGCAGGCATTACCCGCGATTCC
ATTTCGGTCGAATGGGACTGGCGCGGCCGCACCATCAAAATGTTCGATACCGCAGGCATGCGCCGCAAGGCGCGGGTGAC
CGAGAAGCTGGAGAAGCTTTCCGTCGCCGACGCGCTGCGCGCCATCCGTTTTGCCGAAACCGTCGTCATCGTCTTCGATG
CGACGATCCCTTTCGAGAAGCAGGATCTGCAGATCGTCGATCTCGTGCTGCGCGAAGGCCGCGCGGCCGTGCTCGCCTTC
AACAAGTGGGACATGATCGAAGACCGGCAGGCGGTGCTTGCCGATCTTCGCGAAAAGACCGACCGGCTGCTGCCGCAGGC
GCGCGGCATCCGCGCTGTGCCGATCTCCGGCCAGACCGGCTGGGGCCTCGACAAGCTGATGCAGTCGATCATCGACACGG
ACAGGGTCTGGAACAAGCGCATTTCGACGGCAAAGCTTAATCGCTGGCTGGAAACGCAGCAGATCCAGCACCCGCCACCG
GCCGTTTCCGGCCGCCGGATCAAGCTGAAATATATGACGCAGGTGAAGGCCCGTCCGCCGGCCTTCATGATCTCCTGCAC
CCGTTCGGATGCCCTGCCGGAATCCTATACGCGCTATCTGATCAACGGCTTGCGCGCCGATTTCGACATGCCGAGTGTGC
CGATCCGTATTCATTTCCGTTCAGCTGAGAATCCGTTCGAAGGCAAGAAGAGGCGGACGTAG

Upstream 100 bases:

>100_bases
AGCCCGCGAAATGTTACCAATCGCGCTCATATGATGCTTGATCTCATTACCGCATCCGGCAAGGCGCCCGCCGCGCAGGG
CTGAGTTTTAAGGAAAAAGA

Downstream 100 bases:

>100_bases
GGCGCCTGTTGGTGCCTTGAGGAATGTCCGTTTGGGTCGTGCTTGGGTTACCCCCCTCTGGCTTGCCGGGCATCTTCCCC
ACAAGGAGGGAGATCGACTC

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MSFTVAIVGRPNVGKSTLFNRLVGKKLALVDDTPGVTRDRRPGDARLMGLTFTIIDTAGLEEADEESLQGRMRAQTEAAI
DEADLSLFVVDAKNGLTPVDTALAEMLRRRGKPVVLVANKSEARGSDSGFYDAYTLGLGEPTPISAEHGEGMLDLRDAIV
EAIGKDRAYAKEDVAVTNVDISEAAGEGEDEDEEPLYDDTKPLRVAIVGRPNAGKSTLINRFLGEDRLLTGPEAGITRDS
ISVEWDWRGRTIKMFDTAGMRRKARVTEKLEKLSVADALRAIRFAETVVIVFDATIPFEKQDLQIVDLVLREGRAAVLAF
NKWDMIEDRQAVLADLREKTDRLLPQARGIRAVPISGQTGWGLDKLMQSIIDTDRVWNKRISTAKLNRWLETQQIQHPPP
AVSGRRIKLKYMTQVKARPPAFMISCTRSDALPESYTRYLINGLRADFDMPSVPIRIHFRSAENPFEGKKRRT

Sequences:

>Translated_473_residues
MSFTVAIVGRPNVGKSTLFNRLVGKKLALVDDTPGVTRDRRPGDARLMGLTFTIIDTAGLEEADEESLQGRMRAQTEAAI
DEADLSLFVVDAKNGLTPVDTALAEMLRRRGKPVVLVANKSEARGSDSGFYDAYTLGLGEPTPISAEHGEGMLDLRDAIV
EAIGKDRAYAKEDVAVTNVDISEAAGEGEDEDEEPLYDDTKPLRVAIVGRPNAGKSTLINRFLGEDRLLTGPEAGITRDS
ISVEWDWRGRTIKMFDTAGMRRKARVTEKLEKLSVADALRAIRFAETVVIVFDATIPFEKQDLQIVDLVLREGRAAVLAF
NKWDMIEDRQAVLADLREKTDRLLPQARGIRAVPISGQTGWGLDKLMQSIIDTDRVWNKRISTAKLNRWLETQQIQHPPP
AVSGRRIKLKYMTQVKARPPAFMISCTRSDALPESYTRYLINGLRADFDMPSVPIRIHFRSAENPFEGKKRRT
>Mature_472_residues
SFTVAIVGRPNVGKSTLFNRLVGKKLALVDDTPGVTRDRRPGDARLMGLTFTIIDTAGLEEADEESLQGRMRAQTEAAID
EADLSLFVVDAKNGLTPVDTALAEMLRRRGKPVVLVANKSEARGSDSGFYDAYTLGLGEPTPISAEHGEGMLDLRDAIVE
AIGKDRAYAKEDVAVTNVDISEAAGEGEDEDEEPLYDDTKPLRVAIVGRPNAGKSTLINRFLGEDRLLTGPEAGITRDSI
SVEWDWRGRTIKMFDTAGMRRKARVTEKLEKLSVADALRAIRFAETVVIVFDATIPFEKQDLQIVDLVLREGRAAVLAFN
KWDMIEDRQAVLADLREKTDRLLPQARGIRAVPISGQTGWGLDKLMQSIIDTDRVWNKRISTAKLNRWLETQQIQHPPPA
VSGRRIKLKYMTQVKARPPAFMISCTRSDALPESYTRYLINGLRADFDMPSVPIRIHFRSAENPFEGKKRRT

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=477, Percent_Identity=41.0901467505241, Blast_Score=326, Evalue=2e-90,
Organism=Escherichia coli, GI2367268, Length=166, Percent_Identity=37.3493975903614, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1788919, Length=150, Percent_Identity=32, Blast_Score=73, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6323665, Length=162, Percent_Identity=32.7160493827161, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 52603; Mature: 52472

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFTVAIVGRPNVGKSTLFNRLVGKKLALVDDTPGVTRDRRPGDARLMGLTFTIIDTAGL
CCEEEEEEECCCCCHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCEEEEEEEEEEECCCC
EEADEESLQGRMRAQTEAAIDEADLSLFVVDAKNGLTPVDTALAEMLRRRGKPVVLVANK
CCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECC
SEARGSDSGFYDAYTLGLGEPTPISAEHGEGMLDLRDAIVEAIGKDRAYAKEDVAVTNVD
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECC
ISEAAGEGEDEDEEPLYDDTKPLRVAIVGRPNAGKSTLINRFLGEDRLLTGPEAGITRDS
HHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEECCCCCCCCCCC
ISVEWDWRGRTIKMFDTAGMRRKARVTEKLEKLSVADALRAIRFAETVVIVFDATIPFEK
EEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCC
QDLQIVDLVLREGRAAVLAFNKWDMIEDRQAVLADLREKTDRLLPQARGIRAVPISGQTG
CCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
WGLDKLMQSIIDTDRVWNKRISTAKLNRWLETQQIQHPPPAVSGRRIKLKYMTQVKARPP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEHHCCCCC
AFMISCTRSDALPESYTRYLINGLRADFDMPSVPIRIHFRSAENPFEGKKRRT
EEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
SFTVAIVGRPNVGKSTLFNRLVGKKLALVDDTPGVTRDRRPGDARLMGLTFTIIDTAGL
CEEEEEEECCCCCHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCEEEEEEEEEEECCCC
EEADEESLQGRMRAQTEAAIDEADLSLFVVDAKNGLTPVDTALAEMLRRRGKPVVLVANK
CCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECC
SEARGSDSGFYDAYTLGLGEPTPISAEHGEGMLDLRDAIVEAIGKDRAYAKEDVAVTNVD
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECC
ISEAAGEGEDEDEEPLYDDTKPLRVAIVGRPNAGKSTLINRFLGEDRLLTGPEAGITRDS
HHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEECCCCCCCCCCC
ISVEWDWRGRTIKMFDTAGMRRKARVTEKLEKLSVADALRAIRFAETVVIVFDATIPFEK
EEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCC
QDLQIVDLVLREGRAAVLAFNKWDMIEDRQAVLADLREKTDRLLPQARGIRAVPISGQTG
CCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
WGLDKLMQSIIDTDRVWNKRISTAKLNRWLETQQIQHPPPAVSGRRIKLKYMTQVKARPP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEHHCCCCC
AFMISCTRSDALPESYTRYLINGLRADFDMPSVPIRIHFRSAENPFEGKKRRT
EEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA