Click here to switch to the map view.

The map label for this gene is lrp [H]

Identifier: 209550300

GI number: 209550300

Start: 2767810

End: 2768277

Strand: Reverse

Name: lrp [H]

Synonym: Rleg2_2720

Alternate gene names: 209550300

Gene position: 2768277-2767810 (Counterclockwise)

Preceding gene: 209550307

Following gene: 209550297

Centisome position: 61.0

GC content: 61.97

Gene sequence:

>468_bases
GTGGGTCGCGCCGAACTCGACGTCATCGACATAAAGATCCTCCGGGAATTGCAGGCCGACGGCCGCATGACCAATGTGGA
GCTGGCCGACCGCGTCGGCATCTCGGCACCGCCATGCCTGCGCCGGGTGCGCAAGCTCGAGGAAGCGGGCATCATCGAGG
GCTACCATGCGATGCTGAACAGCCCGAGGCTCGGCTTCGACCTCGTCGCTTTCTGCATGGTCGGCCTCAAGCATCAGTCG
GAAGGCAATCTCAAGTCCTTTGCCGCCGCCACCGCCGAATGGCCGCTGGTGCGCCAGGCCTGGATGGTTTCGGGCGACAG
CGATTTCCTGCTGCATTGCGTGGCTGAAAATCTCACCCACTTCCAGGATTTCGTCATCGAGGTGCTGACGGCGAACGAAC
ATGTCGATACCGTGCGCACCATGCTGACGATCCGGCAGGTGAAGAAGCTGGGACTGGTCGAAGTCTGA

Upstream 100 bases:

>100_bases
GGCCGGATGTGCAAGAATCCGTCATCGGCGTGAAACATTCTTGCGTATTCCGCGGCTTTATATAGAAGCTCCCCGCGGAG
AATTAAAGAAAGGCCATGAT

Downstream 100 bases:

>100_bases
AGCTGTCTAAAGCGCGTCGCGATCTTTCACATTCGCTCGTTGCGCTTTAGGTTTTTTACGCATGTCGTTGCCGCAAAACC
GCTGCACACTTTTGCGCGAC

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MGRAELDVIDIKILRELQADGRMTNVELADRVGISAPPCLRRVRKLEEAGIIEGYHAMLNSPRLGFDLVAFCMVGLKHQS
EGNLKSFAAATAEWPLVRQAWMVSGDSDFLLHCVAENLTHFQDFVIEVLTANEHVDTVRTMLTIRQVKKLGLVEV

Sequences:

>Translated_155_residues
MGRAELDVIDIKILRELQADGRMTNVELADRVGISAPPCLRRVRKLEEAGIIEGYHAMLNSPRLGFDLVAFCMVGLKHQS
EGNLKSFAAATAEWPLVRQAWMVSGDSDFLLHCVAENLTHFQDFVIEVLTANEHVDTVRTMLTIRQVKKLGLVEV
>Mature_154_residues
GRAELDVIDIKILRELQADGRMTNVELADRVGISAPPCLRRVRKLEEAGIIEGYHAMLNSPRLGFDLVAFCMVGLKHQSE
GNLKSFAAATAEWPLVRQAWMVSGDSDFLLHCVAENLTHFQDFVIEVLTANEHVDTVRTMLTIRQVKKLGLVEV

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=145, Percent_Identity=37.9310344827586, Blast_Score=105, Evalue=1e-24,
Organism=Escherichia coli, GI87081742, Length=143, Percent_Identity=27.972027972028, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 17328; Mature: 17197

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRAELDVIDIKILRELQADGRMTNVELADRVGISAPPCLRRVRKLEEAGIIEGYHAMLN
CCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHC
SPRLGFDLVAFCMVGLKHQSEGNLKSFAAATAEWPLVRQAWMVSGDSDFLLHCVAENLTH
CCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHH
FQDFVIEVLTANEHVDTVRTMLTIRQVKKLGLVEV
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GRAELDVIDIKILRELQADGRMTNVELADRVGISAPPCLRRVRKLEEAGIIEGYHAMLN
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHC
SPRLGFDLVAFCMVGLKHQSEGNLKSFAAATAEWPLVRQAWMVSGDSDFLLHCVAENLTH
CCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHH
FQDFVIEVLTANEHVDTVRTMLTIRQVKKLGLVEV
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11157937; 11481430 [H]