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The map label for this gene is murB [H]

Identifier: 209550172

GI number: 209550172

Start: 2631400

End: 2632374

Strand: Reverse

Name: murB [H]

Synonym: Rleg2_2592

Alternate gene names: 209550172

Gene position: 2632374-2631400 (Counterclockwise)

Preceding gene: 209550173

Following gene: 209550170

Centisome position: 58.01

GC content: 62.05

Gene sequence:

>975_bases
ATGAAACAGGTGAATGGGGAAAAGCTTCTCGCGTCTCTCGGAGACGGTGTAAAGGATATCCGCGGTCGCATCACGCCGGA
TGCCCCCATGGACCGCGTCACCTGGTTCAGGGCAGGCGGCCTCGCCGAGCTGATGTTCCAGCCGCATGATATCGACGATC
TCGTCGCCTTCCTGAAAATCTTGCCGGAAGAGGTGCCGCTGACGGTGATCGGTGTCGGCTCCAACATCCTGGTGCGCGAC
GGCGGCATTCCCGGCGTCGTGCTGCGCCTGTCCGCCAAGGGCTTCGGCTTCGTCGAGCTTGCCGGCGAAAACCGCATTCT
GGCCGGCAGCATCTGCCCGGATAAACATGTGGCGGCGATGGCGATGGATAACGGCATCGGCGGCTTTCATTTCTTCTACG
GTATTCCGGGCAGCATCGGTGGTGCAGCGCGCATGAATGCCGGGGCCAATGGCGTGGAGACGCGCGAGCGGCTGATCGAG
GTCAACGCGGTCGACCGCAAGGGCAACAAGCACGTGCTGTCCAATGCCGAGATGGGCTATTCCTATCGTCATTCGACCGC
ATCCAGCGAGCTGATCTTCACCTCCGTGCTGTTCGAAGGCTATCCGGAAGAGCGCGCCCAGATCCGCGCCGAGATGGACG
CCGTGCGCAATCATCGCGAGACGGTGCAGCCGGTGCGCGAAAAGACCGGCGGCTCGACCTTCAAGAACCCTGCCGGCCAT
TCGGCCTGGAAACTGATCGACGAGGCAGGCTGCCGCGGTCTCGTCATCGGCGGAGCGCAGATGTCGTCGCTTCACTGCAA
CTTCATGATCAACATGGGGCAGGCGACCGGCTACGATCTCGAATATCTCGGCGAACAGGTGCGCCGCGAAGTCTTCGAGA
AAGAGGGCATCAAGCTCGAATGGGAAATCAAGCGCCTCGGCGTCTTCATGCCCGGCCGCGAAGTGCGCCCATTCCACGGC
GTCACCAGCGAATAG

Upstream 100 bases:

>100_bases
CAAAGCCTGGCGATTTCGTGGTTCTGTTGGGGGCTGGGAGCATCACATCCTGGGCGGCGGCGCTGCCCAAGCAACTGGAA
GGCCTATCGGGAAAGTCCGT

Downstream 100 bases:

>100_bases
CTTTTTACTTCACGGCAAGCTTCAGACCTTCGCGCGGCGTGACGATGGGCGACCAGCCGAGCACGTTGCGGGCGTGGGAT
ATATCGACCTGCAGGGAACC

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MKQVNGEKLLASLGDGVKDIRGRITPDAPMDRVTWFRAGGLAELMFQPHDIDDLVAFLKILPEEVPLTVIGVGSNILVRD
GGIPGVVLRLSAKGFGFVELAGENRILAGSICPDKHVAAMAMDNGIGGFHFFYGIPGSIGGAARMNAGANGVETRERLIE
VNAVDRKGNKHVLSNAEMGYSYRHSTASSELIFTSVLFEGYPEERAQIRAEMDAVRNHRETVQPVREKTGGSTFKNPAGH
SAWKLIDEAGCRGLVIGGAQMSSLHCNFMINMGQATGYDLEYLGEQVRREVFEKEGIKLEWEIKRLGVFMPGREVRPFHG
VTSE

Sequences:

>Translated_324_residues
MKQVNGEKLLASLGDGVKDIRGRITPDAPMDRVTWFRAGGLAELMFQPHDIDDLVAFLKILPEEVPLTVIGVGSNILVRD
GGIPGVVLRLSAKGFGFVELAGENRILAGSICPDKHVAAMAMDNGIGGFHFFYGIPGSIGGAARMNAGANGVETRERLIE
VNAVDRKGNKHVLSNAEMGYSYRHSTASSELIFTSVLFEGYPEERAQIRAEMDAVRNHRETVQPVREKTGGSTFKNPAGH
SAWKLIDEAGCRGLVIGGAQMSSLHCNFMINMGQATGYDLEYLGEQVRREVFEKEGIKLEWEIKRLGVFMPGREVRPFHG
VTSE
>Mature_324_residues
MKQVNGEKLLASLGDGVKDIRGRITPDAPMDRVTWFRAGGLAELMFQPHDIDDLVAFLKILPEEVPLTVIGVGSNILVRD
GGIPGVVLRLSAKGFGFVELAGENRILAGSICPDKHVAAMAMDNGIGGFHFFYGIPGSIGGAARMNAGANGVETRERLIE
VNAVDRKGNKHVLSNAEMGYSYRHSTASSELIFTSVLFEGYPEERAQIRAEMDAVRNHRETVQPVREKTGGSTFKNPAGH
SAWKLIDEAGCRGLVIGGAQMSSLHCNFMINMGQATGYDLEYLGEQVRREVFEKEGIKLEWEIKRLGVFMPGREVRPFHG
VTSE

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 35371; Mature: 35371

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQVNGEKLLASLGDGVKDIRGRITPDAPMDRVTWFRAGGLAELMFQPHDIDDLVAFLKI
CCCCCHHHHHHHHCCCHHHHCCCCCCCCCCCHHHEEECCCHHEEHCCCCCHHHHHHHHHH
LPEEVPLTVIGVGSNILVRDGGIPGVVLRLSAKGFGFVELAGENRILAGSICPDKHVAAM
CCCCCCEEEEECCCEEEEECCCCCEEEEEEECCCCEEEEECCCCEEEECCCCCCCCEEEE
AMDNGIGGFHFFYGIPGSIGGAARMNAGANGVETRERLIEVNAVDRKGNKHVLSNAEMGY
EECCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHEEEEEEECCCCCCEEECCCCCCC
SYRHSTASSELIFTSVLFEGYPEERAQIRAEMDAVRNHRETVQPVREKTGGSTFKNPAGH
EECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
SAWKLIDEAGCRGLVIGGAQMSSLHCNFMINMGQATGYDLEYLGEQVRREVFEKEGIKLE
HHHHHHHHCCCCEEEEECCEECEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEE
WEIKRLGVFMPGREVRPFHGVTSE
EEEEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MKQVNGEKLLASLGDGVKDIRGRITPDAPMDRVTWFRAGGLAELMFQPHDIDDLVAFLKI
CCCCCHHHHHHHHCCCHHHHCCCCCCCCCCCHHHEEECCCHHEEHCCCCCHHHHHHHHHH
LPEEVPLTVIGVGSNILVRDGGIPGVVLRLSAKGFGFVELAGENRILAGSICPDKHVAAM
CCCCCCEEEEECCCEEEEECCCCCEEEEEEECCCCEEEEECCCCEEEECCCCCCCCEEEE
AMDNGIGGFHFFYGIPGSIGGAARMNAGANGVETRERLIEVNAVDRKGNKHVLSNAEMGY
EECCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHEEEEEEECCCCCCEEECCCCCCC
SYRHSTASSELIFTSVLFEGYPEERAQIRAEMDAVRNHRETVQPVREKTGGSTFKNPAGH
EECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
SAWKLIDEAGCRGLVIGGAQMSSLHCNFMINMGQATGYDLEYLGEQVRREVFEKEGIKLE
HHHHHHHHCCCCEEEEECCEECEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEE
WEIKRLGVFMPGREVRPFHGVTSE
EEEEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA