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The map label for this gene is ykcC [H]

Identifier: 209550080

GI number: 209550080

Start: 2529882

End: 2530937

Strand: Reverse

Name: ykcC [H]

Synonym: Rleg2_2497

Alternate gene names: 209550080

Gene position: 2530937-2529882 (Counterclockwise)

Preceding gene: 209550081

Following gene: 209550079

Centisome position: 55.77

GC content: 63.73

Gene sequence:

>1056_bases
ATGACGCAAGCACCGTCTCTTTCCATCGTCGCGCCTTGTCACAACGAGGAAGAGGGGCTGCGCGAGTTCTGCCGCCGCGC
CGCCGCTGCCGCGCAGAGCGTTGCCGGCGACGCCTTTGAGCTCATCCTCGTCGATGACGGATCGTCCGACGGCACCTGGG
AGATCATCTCGGATCTGGCGGAAAAACTGCCGCAGGTGCTCGGCGTTCGTCTCCTGCGCAATCACGGCCACCAACTGGCC
TCGACCGCCGGTCTTTCCGCGTCGCGGGGCGAGCGCGTTCTTTTGATCGACGCCGATCTTCAGGATCCGCCCGAGCTGCT
GTTGATGATGATGCCGATCATGGAGCGCGGCGCCGATGTCGTTTACGGCCAGCGCACGCGCCGCGAAGGCGAAAGCTGGT
TCAAGCTCGCCTCCGCCTCGCTTTTTTATCGTGCGCTTTCCAGGCTCGCTTCCGTGACGATCCCGCGCGATACCGGCGAT
TTCCGGCTGATGCGCCGGCGCGTGGTCGATATTCTGCTGGCGATGCCGGAGCGCGATCGCTTCATTCGCGGCATGGTCAG
CTGGATCGGCGGCAAGCAGGTGGCGCTTCCCTATGAGCGCGACGCCCGTTTTGCCGGCACGACGAAATATCCGCTGCGCA
AGATGATCAATTTCGCGCTCGATGCGATCACCAGTTTTTCCACGACACCACTGCGCATCGCCACATGGCTCGGCATGATC
AGCGCCGGCGTCGCGATGGCGCTGCTCGTCTATACCTTCGTGCGCTGGCTGCAGGGCGAGACGGTCACCGGCTGGTCGTC
GATCATGGCCGCCGTCAGTGCCTTCAGCGCCATCCAGCTGATCTGCATCGGCATCATCGGCGAATATCTCGGCCGTCTCG
TGCAGGAGAGCAAGAGGCGGCCGATGTTCATGATCGAGACCATCCTGCGCGGCGGCGAACATGCCGAGCTGCCGACGGCT
TTTTCGGAGATGAGCGCCGGCGACAAGCGCTCCGCGCTGGATGCAGCCTTTGCATCCGGTGAGCCGCGCTCGCAAAAGAA
CAGCCGGATCGGATGA

Upstream 100 bases:

>100_bases
GCATTCAAGGATGTTCGGCGGCGGCCATCCGGTCATTAAAGGATGTTTGACGTTTCCGGGCTAGGCTGGCGCTATCAATC
AAGCAGGCACCGCCGTCCGC

Downstream 100 bases:

>100_bases
TGGACCGGATTGCCGCGCCTGTTCATTCGGCAGCCAGGCCCGAAGAATTGGTTGCCAGGCAGGATTCCACCATTGCGATC
ATTGCTTTCGTCGCGCTTGC

Product: family 2 glycosyl transferase

Products: GDP; dolichyl D-mannosyl phosphate

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MTQAPSLSIVAPCHNEEEGLREFCRRAAAAAQSVAGDAFELILVDDGSSDGTWEIISDLAEKLPQVLGVRLLRNHGHQLA
STAGLSASRGERVLLIDADLQDPPELLLMMMPIMERGADVVYGQRTRREGESWFKLASASLFYRALSRLASVTIPRDTGD
FRLMRRRVVDILLAMPERDRFIRGMVSWIGGKQVALPYERDARFAGTTKYPLRKMINFALDAITSFSTTPLRIATWLGMI
SAGVAMALLVYTFVRWLQGETVTGWSSIMAAVSAFSAIQLICIGIIGEYLGRLVQESKRRPMFMIETILRGGEHAELPTA
FSEMSAGDKRSALDAAFASGEPRSQKNSRIG

Sequences:

>Translated_351_residues
MTQAPSLSIVAPCHNEEEGLREFCRRAAAAAQSVAGDAFELILVDDGSSDGTWEIISDLAEKLPQVLGVRLLRNHGHQLA
STAGLSASRGERVLLIDADLQDPPELLLMMMPIMERGADVVYGQRTRREGESWFKLASASLFYRALSRLASVTIPRDTGD
FRLMRRRVVDILLAMPERDRFIRGMVSWIGGKQVALPYERDARFAGTTKYPLRKMINFALDAITSFSTTPLRIATWLGMI
SAGVAMALLVYTFVRWLQGETVTGWSSIMAAVSAFSAIQLICIGIIGEYLGRLVQESKRRPMFMIETILRGGEHAELPTA
FSEMSAGDKRSALDAAFASGEPRSQKNSRIG
>Mature_350_residues
TQAPSLSIVAPCHNEEEGLREFCRRAAAAAQSVAGDAFELILVDDGSSDGTWEIISDLAEKLPQVLGVRLLRNHGHQLAS
TAGLSASRGERVLLIDADLQDPPELLLMMMPIMERGADVVYGQRTRREGESWFKLASASLFYRALSRLASVTIPRDTGDF
RLMRRRVVDILLAMPERDRFIRGMVSWIGGKQVALPYERDARFAGTTKYPLRKMINFALDAITSFSTTPLRIATWLGMIS
AGVAMALLVYTFVRWLQGETVTGWSSIMAAVSAFSAIQLICIGIIGEYLGRLVQESKRRPMFMIETILRGGEHAELPTAF
SEMSAGDKRSALDAAFASGEPRSQKNSRIG

Specific function: Involved In O Antigen Modification. Catalyzes The Transfer Of The Glucose Residue From Udp-Glucose To A Lipid Carrier (By Similarity). [C]

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family. GtrB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788692, Length=306, Percent_Identity=36.6013071895425, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI1788588, Length=314, Percent_Identity=31.5286624203822, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1787259, Length=95, Percent_Identity=36.8421052631579, Blast_Score=65, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24585265, Length=244, Percent_Identity=26.2295081967213, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: 2.4.1.83

Molecular weight: Translated: 38674; Mature: 38543

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQAPSLSIVAPCHNEEEGLREFCRRAAAAAQSVAGDAFELILVDDGSSDGTWEIISDLA
CCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHH
EKLPQVLGVRLLRNHGHQLASTAGLSASRGERVLLIDADLQDPPELLLMMMPIMERGADV
HHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCE
VYGQRTRREGESWFKLASASLFYRALSRLASVTIPRDTGDFRLMRRRVVDILLAMPERDR
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHH
FIRGMVSWIGGKQVALPYERDARFAGTTKYPLRKMINFALDAITSFSTTPLRIATWLGMI
HHHHHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
SAGVAMALLVYTFVRWLQGETVTGWSSIMAAVSAFSAIQLICIGIIGEYLGRLVQESKRR
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PMFMIETILRGGEHAELPTAFSEMSAGDKRSALDAAFASGEPRSQKNSRIG
CHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TQAPSLSIVAPCHNEEEGLREFCRRAAAAAQSVAGDAFELILVDDGSSDGTWEIISDLA
CCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHH
EKLPQVLGVRLLRNHGHQLASTAGLSASRGERVLLIDADLQDPPELLLMMMPIMERGADV
HHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCE
VYGQRTRREGESWFKLASASLFYRALSRLASVTIPRDTGDFRLMRRRVVDILLAMPERDR
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHH
FIRGMVSWIGGKQVALPYERDARFAGTTKYPLRKMINFALDAITSFSTTPLRIATWLGMI
HHHHHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
SAGVAMALLVYTFVRWLQGETVTGWSSIMAAVSAFSAIQLICIGIIGEYLGRLVQESKRR
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PMFMIETILRGGEHAELPTAFSEMSAGDKRSALDAAFASGEPRSQKNSRIG
CHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GDPmannose; dolichyl phosphate

Specific reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]