Click here to switch to the map view.

The map label for this gene is 209549980

Identifier: 209549980

GI number: 209549980

Start: 2455496

End: 2456545

Strand: Reverse

Name: 209549980

Synonym: Rleg2_2396

Alternate gene names: NA

Gene position: 2456545-2455496 (Counterclockwise)

Preceding gene: 209549983

Following gene: 209549977

Centisome position: 54.13

GC content: 62.38

Gene sequence:

>1050_bases
ATGACGAAGCCGCCTCGTAAACCCTCACAGCCGCTGCTCGGTAACGTTGACGCACCCATCCGCAGCCGGCCGCGCCGGCG
GCGCGATCCAGCCCAGCCGAACCTTCCCCTCGATCCAATGCCTGCCCGCATCGAGCCTTGTCTAGCGCTCCTCAAGCCGA
AGCCGCCGAAAGGCGCGCAATGGTCGTTTGAGGTGAAATGGGATGGCTATCGCATTGCCGTTCACATCGCACCATCTGGC
GTTCACATCCTGACACGTGGCGGTCATGACTGGACGCACCGCTTCCCGGCGATCGCGGCCGAAGCAGCGCAGCTCGGCGC
GGCGACGGCAATCCTCGATGGCGAAGCTGTGGTGCTGGATGACCAGGGCCGCTCGGATTTCGGCAAGCTGCAGCAGTCGC
TCGGCGGCCGGGGCGGGAAGCTGAATTCCGGCGCATCGGTCCTAATGGCTTTCGATCTTCTATATTTCGACGGCCACGAT
CTGACGAAGACGGAGCTTTCGACGCGACGGCACTTGCTCGAGGGGCTGATCGCACCAGGCCGGGAAAGTTCGATACGGCT
CTCGGAAGACGTCGACGCCGATGGCGAGCAGCTGCTGCGTGTCGCTTGCGAGCACGGGCTCGAAGGTATCATCGCGAAAG
ACCGCAACAGCCCGTATCGCAGCGGCCGCGGCGGCGATTGGCTCAAGATCAAATGCATCCAGAGCGATGGCTTCGCGATC
ATCGGCTACGAGAATTCGACGGCAGCTTTCGGCGGCATCGGCCGGCTGCTGCTTGCCGCGCGCAAAGGAGATGAGCTCGT
CTATGTTGGTGGAGTGGGGACGGGGTTCAACGAGCGTTCCGCGGCCGAGCTCCGAGAGCAGATGGACAAGCTGATCATAC
CCCAGCCGGCCGTCAACACCGGACGCAAGCGCAACGCGGTCTTTATCGAACCGAAGCTTGTCGCCGAGATCGAATATCGA
GGATCGACCAACGACGGGAAGCTCAGGCACGCCTCATATAAGGGGCTGAGGGAGAAGCAGGACAACGCGGCGGTTTATGA
GATTGCTTAA

Upstream 100 bases:

>100_bases
GGCCGTCTCGCCGATGTTCTTATTATGTTCACGCTCGTATCGGAGTCAATAATCATTCTTGGTCAATTGCTTTTTAAGGC
ATTGCTGATGAAGTGCCGGC

Downstream 100 bases:

>100_bases
CGGGTGGCTCGCTCGTATCTCACGTGAGCTTTCAGGACGCCAGCTTCCGCAAGCATTTGGAGGCCACCACCAAATTATAA
GCCGTCACGGCTAATGCCGC

Product: DNA polymerase LigD, ligase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MTKPPRKPSQPLLGNVDAPIRSRPRRRRDPAQPNLPLDPMPARIEPCLALLKPKPPKGAQWSFEVKWDGYRIAVHIAPSG
VHILTRGGHDWTHRFPAIAAEAAQLGAATAILDGEAVVLDDQGRSDFGKLQQSLGGRGGKLNSGASVLMAFDLLYFDGHD
LTKTELSTRRHLLEGLIAPGRESSIRLSEDVDADGEQLLRVACEHGLEGIIAKDRNSPYRSGRGGDWLKIKCIQSDGFAI
IGYENSTAAFGGIGRLLLAARKGDELVYVGGVGTGFNERSAAELREQMDKLIIPQPAVNTGRKRNAVFIEPKLVAEIEYR
GSTNDGKLRHASYKGLREKQDNAAVYEIA

Sequences:

>Translated_349_residues
MTKPPRKPSQPLLGNVDAPIRSRPRRRRDPAQPNLPLDPMPARIEPCLALLKPKPPKGAQWSFEVKWDGYRIAVHIAPSG
VHILTRGGHDWTHRFPAIAAEAAQLGAATAILDGEAVVLDDQGRSDFGKLQQSLGGRGGKLNSGASVLMAFDLLYFDGHD
LTKTELSTRRHLLEGLIAPGRESSIRLSEDVDADGEQLLRVACEHGLEGIIAKDRNSPYRSGRGGDWLKIKCIQSDGFAI
IGYENSTAAFGGIGRLLLAARKGDELVYVGGVGTGFNERSAAELREQMDKLIIPQPAVNTGRKRNAVFIEPKLVAEIEYR
GSTNDGKLRHASYKGLREKQDNAAVYEIA
>Mature_348_residues
TKPPRKPSQPLLGNVDAPIRSRPRRRRDPAQPNLPLDPMPARIEPCLALLKPKPPKGAQWSFEVKWDGYRIAVHIAPSGV
HILTRGGHDWTHRFPAIAAEAAQLGAATAILDGEAVVLDDQGRSDFGKLQQSLGGRGGKLNSGASVLMAFDLLYFDGHDL
TKTELSTRRHLLEGLIAPGRESSIRLSEDVDADGEQLLRVACEHGLEGIIAKDRNSPYRSGRGGDWLKIKCIQSDGFAII
GYENSTAAFGGIGRLLLAARKGDELVYVGGVGTGFNERSAAELREQMDKLIIPQPAVNTGRKRNAVFIEPKLVAEIEYRG
STNDGKLRHASYKGLREKQDNAAVYEIA

Specific function: Unknown

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

Organism=Homo sapiens, GI4557719, Length=295, Percent_Identity=30.1694915254237, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI85815841, Length=272, Percent_Identity=27.5735294117647, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR014146
- InterPro:   IPR002755
- InterPro:   IPR014144
- InterPro:   IPR014145
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF01896 DNA_primase_S [H]

EC number: NA

Molecular weight: Translated: 38034; Mature: 37903

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPPRKPSQPLLGNVDAPIRSRPRRRRDPAQPNLPLDPMPARIEPCLALLKPKPPKGAQ
CCCCCCCCCCCCCCCCCCCHHCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCC
WSFEVKWDGYRIAVHIAPSGVHILTRGGHDWTHRFPAIAAEAAQLGAATAILDGEAVVLD
EEEEEEECCEEEEEEECCCCEEEEEECCCCHHHHCHHHHHHHHHHCCEEEEECCCEEEEE
DQGRSDFGKLQQSLGGRGGKLNSGASVLMAFDLLYFDGHDLTKTELSTRRHLLEGLIAPG
CCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEEHEECCCCCCHHHHHHHHHHHHHHCCCC
RESSIRLSEDVDADGEQLLRVACEHGLEGIIAKDRNSPYRSGRGGDWLKIKCIQSDGFAI
CCCCEEECCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCEEEEEEEECCCEEE
IGYENSTAAFGGIGRLLLAARKGDELVYVGGVGTGFNERSAAELREQMDKLIIPQPAVNT
EEECCCCCHHHHHHHHHHEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
GRKRNAVFIEPKLVAEIEYRGSTNDGKLRHASYKGLREKQDNAAVYEIA
CCCCCEEEECCEEEEEEEECCCCCCCCEEEHHHHCHHHCCCCCEEEEEC
>Mature Secondary Structure 
TKPPRKPSQPLLGNVDAPIRSRPRRRRDPAQPNLPLDPMPARIEPCLALLKPKPPKGAQ
CCCCCCCCCCCCCCCCCCHHCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCC
WSFEVKWDGYRIAVHIAPSGVHILTRGGHDWTHRFPAIAAEAAQLGAATAILDGEAVVLD
EEEEEEECCEEEEEEECCCCEEEEEECCCCHHHHCHHHHHHHHHHCCEEEEECCCEEEEE
DQGRSDFGKLQQSLGGRGGKLNSGASVLMAFDLLYFDGHDLTKTELSTRRHLLEGLIAPG
CCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEEHEECCCCCCHHHHHHHHHHHHHHCCCC
RESSIRLSEDVDADGEQLLRVACEHGLEGIIAKDRNSPYRSGRGGDWLKIKCIQSDGFAI
CCCCEEECCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCEEEEEEEECCCEEE
IGYENSTAAFGGIGRLLLAARKGDELVYVGGVGTGFNERSAAELREQMDKLIIPQPAVNT
EEECCCCCHHHHHHHHHHEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
GRKRNAVFIEPKLVAEIEYRGSTNDGKLRHASYKGLREKQDNAAVYEIA
CCCCCEEEECCEEEEEEEECCCCCCCCEEEHHHHCHHHCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]